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Associate Scientist / Scientist, Bioanalytical Chemist

South San Francisco, California


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The Position

We have an opening for a talented Associate Scientist / Scientist to join our Biochemical and Cellular Pharmacology Department. The candidate will function as part of various multi-disciplinary teams covering large molecules from all therapeutic areas spanning early stage research to final IND candidate. The successful candidate will have broad research responsibilities involving bioanalytical chemistry tools for characterizing and quantitating protein therapeutics. Responsibilities include developing and implementing high-throughput functional screening and pharmacokinetic/pharmacodynamics assays including biodistribution and biotransformation. For pharmacokinetic studies, defining strategies for incorporating in vitro assays that translate to in vivo systems will be critical. The role will involve identifying, conceiving and working with advanced analytical technologies as well as routinely innovating and pushing technological limits to support the evolving portfolio. In addition, building and enhancing the infrastructure through automating instrumentation, data analysis and informatic workflows will be key to success. The individual will be expected to provide strategic input representing department function in lead finding/optimization and bioanalytical efforts for advancing therapeutic candidates. The role will involve working extensively with contract research organizations, external collaborators and may also involve managing researchers.
Who You Are:
  • Ph.D. in Analytical Chemistry, Pharmacology, Biochemistry or a related field with 4+ years postdoctoral or industry experience (0+ years for Associate Scientist).
  • Experience with bioanalytical chemistry tools involving mass spectrometry, microfluidics, immunoaffinity,  chromatography, and/or spectroscopy is required.
  • Experience with protein quantitation and characterization would be advantageous.  
  • Proven track record of success and high profile publications is required.
  • Practical experience in the design, development, validation and execution of bioanalytical chemistry tools for characterization and quantitation of biomolecules is required.
  • Familiar with multi-disciplinary activities of large molecule drug discovery research involving functional screening, pharmacokinetics and biotransformation.
  • Experience with automating instrumentation and data processing would be advantageous.
  • Strong communication and interpersonal skills is required.
  • Drive for conceiving and implementing highly innovative analytical tools would be advantageous.
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Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

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Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.


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