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Scientist, Preclinical and Translational Pharmacokinetics and Pharmacodynamics

South San Francisco, California

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The Position

The Position

The Preclinical and Translational PKPD (PTPK) department is seeking a scientist who is driven to understand the pharmacokinetics (PK) and pharmacodynamics (PD) of novel drug candidates and delivery systems. The candidate will be responsible for investigating PKPD in preclinical models to guide design, delivery, and development of novel therapeutics, and for translating preclinical PKPD to ensure appropriate dose/regimen decisions using state-of-the-art experimental and quantitative approaches. The candidate will work in a highly collaborative, cross-functional environment, with partnerships across Research, Drug Delivery, Development Sciences, Clinical Sciences, Biostatistics, and Regulatory, to represent PTPK at cross-functional teams, department meetings, review committees, and conferences.

Who you are:

We are looking for individuals who are inspired by our mission and who would fit in well with the collaborative, rigorous, and entrepreneurial spirit of company culture.

  • A Ph.D. in Pharmacokinetics, Pharmaceutical Sciences, Pharmacology, Biomedical Engineering, or related discipline; persons without formal degree who have comparable depth and breadth of training and experience, and who meet job-specific criteria, are eligible for consideration.
  • Minimum of 0+ years (for Associate Scientist), 3+ years (for Scientist), and 7+ years (for Senior Scientist) of relevant PKPD experience and demonstrated impact on drug development and/or the PKPD scientific landscape.

Preferred Qualifications:

  • Strong knowledge and experience in oncology and immunology are highly desirable.
  • Strong knowledge and experience in PKPD of protein and/or RNA therapeutics are highly desirable.
  • Working knowledge of PKPD software (e.g., WinNonlin, R, NONMEM, ADAPT II, SimBiology, etc.) and the ability to analyze and critically assess PKPD data is essential.
  • The candidate should have experience working on cross-functional teams, demonstrate excellent communication skills, and have the ability to work independently and effectively.



Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

The next step is yours. To apply today, click on the "Apply for this job" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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