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Scientific Manager - OMNI Biomarker Development

South San Francisco, California

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The Position

The Position

The department of OMNI Biomarker Development leads biomarker efforts for Phase I through Phase III clinical trials to support novel therapeutics for unmet medical needs. We use relevant pharmacodynamic biomarkers to evaluate target-engagement and mechanism of action as well as diagnostic biomarkers to guide patient selection. Our department is responsible for developing biomarker strategies, designing and implementing biomarker measurements, and interpreting biomarker results. We are seeking a highly motivated Scientific Manager to help support our Ophthalmology projects.


The primary responsibility for this individual will be to manage and help set strategic direction for cross-functional OMNI-BD biomarker subteams, as well as identify, characterize, implement, and analyze biomarkers for use in early and late stage clinical trials for retinal diseases. This individual will also manage and oversee internal and external collaborations involving project biomarker activities.

Success in these responsibilities requires a thorough understanding of disease and drug target biology, strong ability to analyze and interpret data, a pragmatic approach to integrating biomarkers into clinical trials, and ability to plan and deliver results according to timelines.

Effective communication is expected and will include presentations at cross-functional teams, internal review committees, and external conferences. In addition, the individual is expected to contribute to the scientific community by publishing results in high quality journals


• MS or PhD in Biochemistry, Cell Biology, Immunology, Neuroscience, or related discipline with 4+ years of relevant work experience

• A record of high quality research as demonstrated by publications in top tier journals and external presentations is required.

• Excellent communication skills and the ability to work on interdepartmental project teams is required.

• Experience in drug-development and/or familiarity with the cellular/molecular pathways that contribute to retinal disease is a plus.

• Applicants with additional experience are encouraged to apply.


Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

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Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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