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Senior Medical Science Director/Medical Director- Oncology PHC

South San Francisco, California

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The Position

The Senior Medical Science Director/Medical Director for Oncology PHC at Genentech puts patients and science at the center of all actions. He/she drives medical strategy and tactics aimed at maximizing medical progress across all solid tumors for a PHC approach. He/she oversees the cross functional PHC medical team and provides strategic overarching guidance to the individual disease area leads for all solid tumors across our portfolio of medicines. He/she collaborates to drive timely data generation and dissemination as well as chairs the scientific review committee for PHC Oncology projects. He/she is expected to maintain an in-depth understanding of the medical strategy and relevant clinical and payer issues, while ensuring Genentech's partners understand key trends and shifts in the external healthcare landscape. He/she serves as the guardian for high standards of compliance, ethics and safety.  This role is organized within a network of experts, and therefore may at any time be performing a variety of medical activities, as needed. Key Responsibilities for all Medical Science Directors/Medical Directors: In this role the MSD/MD will be required to perform one or more of the following activities depending upon areas of expertise or assignment to specific activities, molecules, or disease/therapeutic areas: Design, execute, and monitor medical strategies, plans and tactics spanning the lifecycle, including but not limited to: clinical data generation design and management, thought leader interactions, sponsored and supported trials and registries, exploratory data analysis, publications, medical content creation and review, scientific exchange/engagement and scientific communications/collaborations, medical education, scientific congress planning and support, evaluate, synthesize, and visualize clinical and economic data and develop written scientific communication, identify access-related medical issues and opportunities.  Actively participate and contribute to relevant communities of practice

Key Accountabilities for all Medical Science Directors/Medical Directors 

Depending upon areas of assignment for specific activities or molecules, disease/therapeutic areas or for the full portfolio, acting as a medical individual for relevant study design and monitoring, data interpretation, medical content development and review, scientific exchange and collaboration, clinical training and insights generation to internal stakeholders and external customers.

  • Accountable for implementing strategy through medical tactics, tapping into the network of relevant expertise and insights

  • Contribute medical expertise to Genentech work products and coach/mentor others as needed

  • Facilitate sharing of information within, across and outside of Medical Affairs to enable medical progress

  • Maintain an in-depth understanding of relevant medical strategy and clinical, patient/caregiver, payer and healthcare/market landscape

  • Act as a guardian for high standards of compliance, ethics and safety; putting patients at the center of all actions

  • Scientific Engagement with Genentech's External Stakeholders: Develop and execute on strategic scientific engagement/collaboration plans and cultivate long-terms strategic partnerships with relevant US-based external experts, academic institutions, professional societies, compendia and guideline entities, and other relevant organizations, including cooperative groups and their foundations, large multi-center research organizations and patient organizations

  • Guide internal teams on relevant external communications and interactions with strategic partners. As needed or otherwise appropriate, help facilitate contact between relevant internal personnel and external strategic partners and provide scientific training to contracted HCP speakers.

Job Requirements Qualification

  • Advanced Clinical/Science Degree Required (e.g. PharmD, PhD, MD, etc.)

  • Required Experience: 3-10 years of pharmaceutical/biotechnology relevant industry experience preferred - preferably in Medical Affairs or product development or is a recognized expert in the field or therapeutic area (with a minimum of 2 years’ clinical experience) 

  • Strong academic/teaching background preferred Understanding of and/or previous experience with Phase I - III and/or Phase IV drug development 

  • Considerable experience in the principles and techniques of data analysis, interpretation and clinical relevance, and medical writing

  • Proven record in developing strong relationships with external constituents (therapeutic area experts, external organizations, etc.) preferred

  • Proven track record of meeting or exceeding objectives and goals Proven cross functional leadership experience and track record of successful leadership without direct authority

  • Proven clinical trial experience


  • Strong customer orientation/focus

  • Ability to flex and thrive in an ambiguous environment undergoing transformational change

  • Works well within teams and is effective in collaborating with others internally and externally Analytical and problem-solving capabilities and skills. Has demonstrated the ability to anticipate and solve problems of moderate complexity and scope e.g. evaluate, interpret and present highly complex data

  • Communication and presentation skills; highly effective at summarizing and presenting key considerations and decision-points

  • Strong business acumen: knows the industry, key competitors, marketplace factors/dynamics

  • Ability to effectively and efficiently manage multiple priorities

  • Excellent interpersonal and influencing skills; can effectively and quickly establish rapport with all key internal/external partners and stakeholders and influence without authority 

  • Excellent negotiation skills: can drive discussions and decisions towards desired results ● Understanding of legal and regulatory considerations impacting pharma/biotech industry and ability and judgement to apply principles to daily activities

  • Strong attention-to-detail

  • Willingness to learn

  • Proven perseverance in changing business landscape

  • Business travel, by air or car, is required for regular internal and external business meetings

Roche is an equal opportunity employer.

CMG Operating Principles

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I put the patient first, always.

I am tenacious in meeting customer needs.

I act on behalf of the whole company, not just my team.

I am inclusive.

I build a culture of trust.

I grow my capabilities to increase my impact.

I have a bias for action.

I am accountable.

I use time and resources to create the most impact.

I act with integrity.

Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

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Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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