We have an exciting position for a Bioconjugation Chemist, Protein Chemist, or Protein Engineer at the scientific researcher/senior scientific researcher level to join the Protein Chemistry department. This position will involve research in the area of bioconjugation methods, polymer synthesis for covalent protein arrays, and the preparation of protein-polymer conjugates, as it relates to the development of hybrid protein therapeutics for the treatment of a variety of diseases. Depending on the candidate’s expertise, responsibilities will include developing new bioconjugation strategies, polymer synthesis, protein-polymer conjugation and protein purification. The individual will also be responsible for rigorous analytical characterization of polymers, proteins, and conjugates. The individual will be expected to work independently in the lab but collaborate with colleagues across various functional areas at Genentech. The candidate will provide synthesis and characterization of complex bioconjugates to programs from basic research through early development, and they are expected to generate and communicate results that meaningfully impact project decisions. The successful candidate will also be expected to contribute to high-impact publications related to the job responsibilities and present at scientific conferences.
A MS or PhD in chemical biology, biology, protein chemistry, biochemistry, biophysics or a related discipline. A candidate with an MS requires 6+ years of experience in related work. A PhD needs 2+ years of technical experience in these or related areas. Candidates should have demonstrated expertise in bioconjugation to proteins and/or polymers, with a proven track record of publications that are relevant to production of complex protein arrays. The work will involve the design and application of polymer synthesis and/or protein-polymer bioconjugation It will also involve analytical methods including those used for polymer synthesis (NMR, preparative RP, LC/MS, GC/MS, etc.) and/or bioconjugation (HPLC/UHPLC, LC/MS, FPLC, affinity purification, gel filtration, SEC-MALLS, ion exchange chromatography, etc). Expertise with standard text, graphic, and presentation software is required. Excellent communication and interpersonal skills are essential and will be heavily evaluated during the interview process. The ideal candidate will be motivated, and have strong problem-solving, troubleshooting, communication, and organizational skills.
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
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