|Date||Job Title||Job Level||Location|
|11/20/18||GATCF Forecast and Workforce Planning Lead||Individual contributor||South San Francisco, California|
Genentech Access to Care Foundation (The Foundation)
Purpose: The Lead Forecast & Workforce Planning delivers a complete line of site across The Foundation forecasts through a stand-alone, systemized and analytic methodology. The role is required to develop integrated product and portfolio forecasts and plans to support The Foundation and inform decisions for volume forecasts, workforce planning, SAP, COGS, PACT and donations. The role provides analytics to help in The Foundation strategy development.
This position reports directly to the GATCF Lead.
Problem Solving & Decision Making: The leader manages all financial and workforce planning needs to ensure all stakeholders vested to The Foundation can make well-informed decisions for portfolio inventory management, funds required from the Donor for portfolio shipments to patients, and necessary workforce requirements to manage the demand of service requests for The Foundation in an efficient manner. The Foundation requires this leader to build analytic capabilities in a systemized and standardized fashion to appease all stakeholders with minimal error left to manual manipulation. This is required to make better budgeting decisions for portfolio donations, headcount requirements, and operation requirements, while meeting our reporting requirements for auditing and compliance purposes.
Strategic Responsibility: This role builds and delivers analytic capabilities for The Foundation to manage all financial and headcount requirements by anticipating external market event triggers, such as co-pay accumulators and biosimilars. The role will also anticipate internal triggers like new product launches or changes in The Foundation policy on inclusion criteria. This lead provides business analytics support to the Foundation, while proactively identifying risks and ways to mitigate them.
Interaction with Others: The leader will work with and inform various Genentech Leadership Team members on an ongoing basis including: the Donor, the Board, The Foundation LT, MCCO LT, MA&S, Finance, CO, KDC / HDC and franchise LT. The role will also manage and work with third parties required for the financial management of The Foundation: RxC, Lash, McKesson, MedVantx, AZ Associates, GARA.
Required Skills and Experiences:
|11/20/18||Contract Recruiter - US Medical Affairs||Individual contributor||South San Francisco, California|
As a Recruiter, you will partner with senior management in the recruitment of talent to Genentech - individually managing a portfolio of openings and focusing on meeting or exceeding client's expectations and ensuring a positive candidate experience. In this position, you will primarily support Genentech’s US Medical Affairs team, which is part of the overall Commercial, Medical and Government Affairs (CMG) organization. You will work with employees and managers in Medical Affairs to assure that we have the talent required to meet their business objectives. You will foster a team environment and demonstrate collaborative leadership, and will partner with the Human Resource Managers and Talent Acquisition Management to develop and implement recruiting plans and strategies for Medical Affairs.
Additional responsibilities may include:
Teamwork and Collaboration
Strongly prefer candidates based in the San Francisco Bay Area, but open to remote workers with strong and relevant backgrounds for the role.
|11/20/18||Manufacturing Technician, Aseptic Operations||Individual contributor||Hillsboro, Oregon|
Please note this is a Night Shift position, 6:00pm to 6:30am Sunday through Tuesday (every other Saturday)
Qualifications / Requirements:
Roche is an equal opportunity employer.
|11/20/18||Associate Director - Late Stage Analytical Development||Manager without direct reports||South San Francisco, California|
Member of Leadership Team
|11/20/18||Associate Scientist/Scientist (Bioinformatics), Oncology Biomarker Development, Genentech Research||Individual contributor||South San Francisco, California|
Genentech seeks a talented and highly motivated bioinformatics scientist to pursue translational research in collaboration with the Department of Oncology Biomarker Development. The successful candidate will get the opportunity to pair world-class science with human impact.
The primary focus will be on the translation of complex molecular biomarker data, derived from clinical trial samples, into useful diagnostic tools that can guide our understanding of drug activity in patient tumors, characterize mechanisms of acquired drug resistance, and identify subsets of patients who may benefit from specific therapeutic interventions. The candidate will undertake biomarker analysis efforts primarily for breast and gynecological cancers.
We are looking to add a new member to our team with outstanding computational skills, experience with the analysis of large-scale data, and an understanding of cancer biology. A successful candidate will work with interdisciplinary teams (including biomarker, clinical, research and biostatistics scientists), will pursue creative solutions to complex problems via the analysis, integration and interpretation of a variety of data, and apply (or develop) best-in-class methods that address the motivating biological and clinical questions. Regular publication of scientific or methodological results is strongly encouraged. Besides technical expertise, we are looking for someone who is passionate about applying their skills to advance our understanding and treatment of cancer, and who is able to effectively present complex results in a clear and concise manner that is accessible to a diverse audience of quantitative, experimental, and clinical scientists.
Who You Are
|11/20/18||Scientist/Senior Scientist, OMNI-Biomarker Development, Development Sciences||Individual contributor||South San Francisco, California|
We are seeking a highly motivated Scientist or Senior Scientist to join the OMNI-Biomarker Development Department within Development Sciences to drive our personalized healthcare efforts in multiple sclerosis. Our department is responsible for defining biomarker and personalized healthcare strategies, designing and implementing biomarker assays, and interpreting biomarker results. Our group uses relevant biomarkers to evaluate disease heterogeneity, target-engagement, mechanism of action, and disease modification, and to guide clinical diagnostic biomarker development. Biomarker team leaders within the department provide scientific leadership for biomarkers in clinical trials ranging from early proof-of-concept through marketed products.
The successful candidate will join our dynamic team and work to identify and assess personalized healthcare strategies in multiple sclerosis. The candidate will support our multiple sclerosis biomarker strategy, leading efforts for data analyses of internal studies and external collaborations relating to understanding clinical aspects of multiple sclerosis through genetic and other biomarker data across clinical data sets, with the opportunity for the successful Scientist to grow into a project biomarker representative/team leader. Success in these responsibilities requires a thorough understanding of disease and drug target biology, creativity and attention to detail, and experience in integrating biomarkers into clinical trials. Candidates familiar with molecular and immunological techniques including immunoassay, qPCR, whole genome sequencing methods and/or genetic analysis algorithms will be given preference. The position requires working in close partnerships across various functions including Research, Bioanalytical Assays, Diagnostics, Clinical Sciences, Biostatistics, Bioinformatics, Regulatory and with external partners. Effective communication is essential and includes presentations at cross-functional teams, internal review committees, and external conferences, and will also involve writing biomarker sections of clinical protocols, reports, regulatory filings and scientific publications.
Who You Are
Candidates must have a PhD or MD in Neurology, Neuroscience and/or Immunology, or a related field with at least 3 to 5 years of post-doctoral or fellowship experience in basic or translational research either in an academic and/or industry setting. The candidate must demonstrate a high level of independence and be able to develop hypotheses and direct analysis plans. Strong writing and communication skills are required, as evidenced by publications, meeting abstracts and/or drug development reports. We are looking for an individual who would be passionate about using their understanding of disease biology to make impactful contributions to clinical drug development. Willingness to collaborate across time zones including our Swiss site is a must. Preferred candidates will have prior experience in multiple sclerosis and a demonstrated ability to function as part of a cross-functional team such as clinical trial project teams.
|11/20/18||(1 year) Intern - Corporate Groups - Global Pharma Procurement, Direct Materials||Entry Level||South San Francisco, California|
The candidate will be part of Direct Procurement Pharma (DPP), a strategic unit supporting the entire organization including manufacturing, process development and research. Together with our Business Partners we will ensure best value and uninterrupted and compliant supply of materials and services from our suppliers to meet current and future business requirements. The project will be focused on Single Use Technology a category of direct material used in Manufacturing production under the supervision of the global category manager within TOP- Direct Material.
This role will provide an opportunity to join Global Procurement and contribute for a whole year to an exciting and fast growing category of direct materials at Roche; Single Use Technology (SUT). With this project, the analyst will be exposed to the core of category management; the ability to source, manage, and assure supply with the right level of quality and a solid risk management program.
1) Essential to enable a robust supply chain to the GMP network, the analyst will perform a portfolio analysis, through which he/she will develop a solid understanding of where and how SUT materials are used across the DS network and the risk that each material carries. The candidate will need to work well participating in and leading cross functional teams, often globally with stakeholders both internally across PT and externally with Roche key suppliers.
2) In support of single use implementation, the candidate will participate in the development of a standard catalog to drive standardization within the network and support the sourcing of future single use technology.
3) The candidate will participate and assist the global category manager in category management activities, supplier relationship management and sourcing activities. This will include activities like updating databases, refreshing global guide and updating website content as well as participating in executive meeting and managing agenda, minutes and action items.
This position will require strategic thinking, project management, collaboration, communication, some technical/operational skills, influencing abilities, and data management skills.
|11/20/18||Intern- Pharam Technical Operations- PD Engineering||Entry Level||South San Francisco, California|
The Supply Chain Organization connects the different parts of Roche to ensure reliable supply of our innovative medicines to customers and patients. We ensure worldwide reliable supply to patients connecting their needs to the Roche Pharma Global Supply Network. This network consists of Roche manufacturing sites, contract manufacturers and external suppliers. We partner across Pharma to develop and execute agile product lifecycle and network strategies and we design and optimize end-to-end Supply Chains from raw materials to final product throughout the whole product life-cycle.
The intern will model mathematically a multivariate supply planning process, analyze historical data, and apply novel stochastic optimization tools to determine optimum supply plans under uncertainty.QualificationsPreferred degrees Master's level or Ph.D level. Expert in Systems Engineering and Stochastic Optimization.
|11/19/18||Reputation and Issues Management Lead, APAC / Senior Communications Manager||Individual contributor||Basel, Basel-City|
Reputation and Issues Management Lead APAC / Senior Communications Manager
Reporting to the Global Head of Reputation and Issues Management, the Reputation and Issues Management Lead APAC is responsible for shaping both the external environment and Roche’s reputation in order to build a competitive edge and further the company’s business strategy.
S/he is the trusted advisor of the Global Head of Reputation and Issues Management and other senior leaders, and will set, define and oversee the implementation of the overall strategy, objectives and goals for the function in APAC.
S/he is the primary communications contact for APAC, acting as an enabler of the new more networked communications model and providing strategic counsel to the Heads of Corporate Affairs and their respective leadership teams where needed. In this capacity s/he is responsible for ensuring team members maintain a high level of engagement and performance.
S/he is expected to play a leadership role at the global level and will be required to build and lead at least one global community of practice (e.g. Crisis Management, Insight and Reputation Strategy, or a key business topic etc), both enabling and guiding the development of cross-country solutions to find common opportunities and mitigate challenges.
S/he will take the lead on establishing and maintaining issue preparedness - as well as issues management - activities in APAC. In doing so s/he will establish robust governance practices, provide training to leadership teams, identify risks and will subsequently lead cross functional teams through the development and implementation of issues management strategies which tackle business critical topics or key challenges.
The position can be located in any country in the corresponding area.
In this position, you will be primarily accountable for:
|11/19/18||Associate Director, Human Resources||Manager with direct reports||Hillsboro, Oregon|
Associate Director, HR Business Partner, PT (Hillsboro)
In PTG we are working as one integrated Drug Product manufacturing network – across Basel, Clarecastle, Hillsboro, Kaiseraugst, Mannheim, Rio de Janeiro, South San Francisco, Shanghai, and our DP external manufacturing network – to provide a variety of medicines to more patients around the world.
Our mission is clear: across our network and together with our Roche colleagues, we need to work together each day to reliably deliver our pipeline and ensure uninterrupted supply of quality products everywhere and in all forms.
In this role you will lead an HR Organization and you will be accountable to develop and drive business strategy and ensure organizational effectiveness by applying broad functional knowledge, skills and solid judgment and influence the overall objectives and long range goals of the Hillsboro campus.
You will be a member of two client facing leadership teams, Hillsboro Drug Product Manufacturing and PCV Manufacturing leadership teams and accountable to deliver strategic business results, drive employee strategies that will have a deep impact across the PTG network.
This person will possess a full range of proficiency and experience in the following areas of: Workforce Planning, Recruitment, Performance Management, Compensation, Organizational Development, Coaching/Consultation, Talent Management, Succession Planning, Change Management, Project/Program Management and leadership for a team of direct reports.
The AD will apply strong technical expertise, knowledge of the business and environment, and situation specific analysis to develop and implement new concepts, techniques, and standards to address organizational and people-related challenges across the Hillsboro Campus.
Qualifications and Experience:
You are a solid coach and creative problem solver able to analyze strategic choices and business opportunities and you bring the following qualification:
|11/19/18||Companion Diagnostics Project Leader/Sr. Companion Diagnostics Project Leader - Oncology||Individual contributor||South San Francisco, California|
The CDx PL/Sr. CDx PL will guide the strategy and implementation of companion diagnostics in support of projects within Genentech’s extensive Early and Late Development portfolios. The CDx PL/Sr. CDx PL will play a critical role in enabling personalized healthcare for Roche/Genentech therapeutic programs.
The CDx Project Leader will be responsible for the following:
Who You Are
The ideal candidate for the CDx Project Leader/Sr. CDx Project Leader will meet the following qualifications:
|11/19/18||Digital Transformation Leader, PTDS||Individual contributor||South San Francisco, California|
The Digital Transformation Leader will be responsible for setting the strategic vision for digital enhancements in clinical supply, will oversee a portfolio of digital capabilities and may lead various projects to roll out new digital capabilities. The incumbent will act as the liaison between Clinical Operations and the Clinical Supply organization related to digital offerings by Clinical Supply across the clinical trial space. He/she will lead assessments of new technologies and as appropriate will lead the roll out of new capabilities. The successful candidate will be responsible for leading transformation that contributes significantly to the goals and objectives of PTD(S).
|11/19/18||Scientific Researcher / Senior Scientific Researcher, Drug Metabolism and Pharmacokinetics||Individual contributor||South San Francisco, California|
The Position / Responsibilities
We are seeking a highly motivated individual for a Scientific Researcher/Senior Scientific Researcher position in Drug Metabolism and Pharmacokinetics (DMPK) department at Genentech. In the Drug Permeability/Transport lab researchers investigate the cellular permeability of novel small molecules, in particular peptides, and the roles of membrane transporters in the disposition of these drug candidates.
Key responsibilities for this position include hands-on experimentation using cell biology and biochemical techniques to characterize the interactions of peptides (<3000 Da) with cell membranes and drug transporters, thereby elucidating the mechanisms affecting in vivo and cellular permeability/transport and providing project teams with relevant information for the optimization and identification of lead compounds. These data will also be used to explain or enhance the cellular pharmacological response. The qualified candidate must be able to work in a team environment, collaborate with multidisciplinary researchers on various aspects of projects, and meet timelines efficiently and productively.
Qualified candidates will possess the following skills and experience.
Drug Metabolism and Pharmacokinetics (DMPK)
|11/19/18||Senior Scientific Researcher, Biotransformation/drug metabolism||Individual contributor||South San Francisco, California|
The DMPK biotransformation group at Genentech is seeking a highly motivated individual to support development drug metabolism. Primary responsibilities include:
The level of the position is Senior Scientific Researcher (SSR). Qualified candidates will meet the following requirements:
The Drug Metabolism and Pharmacokinetics (DMPK) group at Genentech is dedicated to enabling the discovery, development and commercialization of safe and effective medicines by elucidating the absorption, distribution, metabolism, excretion and pharmacokinetic properties of small molecule drug candidates. We accomplish this through the application of state-of-the-art technologies and sciences of bioanalysis, drug metabolism, drug transport and pharmacokinetics. The DMPK group works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize leads, select clinical candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.
|11/19/18||Associate Scientist/Scientist – Drug Metabolism||Individual contributor||South San Francisco, California|
The Drug Metabolism and Pharmacokinetics (DMPK) group at Genentech is dedicated to enabling the discovery, development and commercialization of safe and effective medicines by elucidating the absorption, distribution, metabolism, excretion and pharmacokinetic properties of small molecule drug candidates. We accomplish this through the application of state of the art technologies and sciences of bioanalysis, drug metabolism, drug transport and pharmacokinetics. The DMPK group works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize leads, select clinical candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.
The DMPK group is seeking a highly motivated individual to apply drug metabolism in drug design. Primary responsibilities include:
The level of the position (Associate Scientist or Scientist) will depend on the qualifications of the selected candidate.
Qualified candidates will meet the following requirements:
|11/19/18||Associate Scientist/Scientist, Drug Metabolism and Pharmacokinetics, Genentech Research||Individual contributor||South San Francisco, California|
We are seeking an exceptional individual for an Associate Scientist/Scientist position in Drug Metabolism and Pharmacokinetics (DMPK) department at Genentech. This position will support our continued efforts to apply physiologically based pharmacokinetic (PBPK) modeling to support discovery and development projects. Meanwhile, the individual will also expected to represent DMPK function in a project setting.
Requirements: A PhD degree specializing in pharmacokinetics and/or drug metabolism or other relevant fields. A strong understanding of PK and ADME concepts, and practical experience in in vitro and in vivo extrapolation in at least one of the following areas: absorption, distribution, enzyme metabolism, transporter and excretion. Hands-on experience in PBPK modelling (eg. Simcyp, Gastroplus or customized models).
Desirable: Good organizational, collaboration, communication skills and flexibility are important assets. 0 – 4 year previous DMPK pharmaceutical industry experience. Familiarity with PK/PD basic methodology and relevant modeling and simulation tools (e.g. WinNonlin, ADAPT, SAAMII ).
|11/19/18||Associate Scientist, Drug Metabolism and Pharmacokinetics - Bioanalysis (DMPK-BA)||Individual contributor||South San Francisco, California|
The DMPK department is dedicated to enabling the discovery, development and commercialization of safe and effective medicines by elucidating the mechanisms of absorption, distribution, metabolism, and excretion of small molecule drug candidates. We accomplish our goals through the application of state-of-the-art technologies for bioanalysis, drug metabolism, drug transport and pharmacokinetics. The DMPK department works in close partnership with disciplines such as medicinal chemistry, in vivo pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize lead compounds, select clinical candidates, conduct preclinical studies, support clinical development and contribute to IND and NDA filings.
The DMPK-BA function is primarily responsible for overseeing regulated bioanalytical activities conducted at contract research laboratories (CROs), and ensuring overall compliance with GLP/GCP regulations to support the preclinical and clinical development of Genentech’s small molecule programs. Responsibilities include, but are not limited to: technical monitoring during bioanalytical method development, validation, and sample analysis; overseeing method transfer between CROs; reviewing validation reports and experimental documentation; and archiving relevant study documents. The individuals in this function also conduct CRO evaluation and selection, review CRO SOPs, determine additional bioanalytical requirements if needed, and perform regular site visits and inspection.
Internally, the individuals are responsible for developing highly sensitive and specific bioanalytical methods for quantitative analysis of new chemical entities, metabolites, and biomarkers in a variety of biological matrices, reproducing CRO-developed methods, and performing non-regulated quantitative bioanalysis. The individuals serve as bioanalytical representatives on inter-disciplinary project teams. In addition, the individuals may supervise and train junior staff to successfully perform all the above-mentioned responsibilities.
The ideal candidate for the DMPK-BA Associate Scientist position typically has a doctoral degree in analytical chemistry, biochemistry, or equivalent with relevant industry experience of 1 to 3 years. The candidate needs to possess a demonstrated ability to work independently in a fast-paced environment, as well as in a team setting. The candidate should have in-depth bioanalytical knowledge and extensive experience with modern analytical instrument platforms, particularly with LC-MS/MS. The candidate is expected to have hands-on experience in developing and validating LC-MS bioanalytical methods using various techniques (SLE, LLE, SPE, and PP), and have strong multi-tasking ability to manage multiple studies simultaneously and be able to assist in troubleshooting when instrument or assay problems arise. The candidate should have a good understanding of GLP/GCP regulations, and possess excellent oral and written communication skills. Prior working experience at or with CROs is preferred.
|11/19/18||Associate Scientist /Scientist, DMPK||Individual contributor||South San Francisco, California|
The Drug Metabolism and Pharmacokinetics (DMPK) department at Genentech is seeking a highly motivated individual who will be involved in the in vitro to in vivo translation of data in the non-clinical space. This position will support our continued efforts to address gaps in in vitro – in vivo correlation and extrapolation (IVIVC and IVIVE). A significant portion (? 50 %) of the time of this position is expected to be spent hands-on in the lab. The expectation is that the individual will be involved in:
Requirements: A PhD degree specializing in pharmacokinetics and/or drug metabolism or other relevant fields. Direct experience with common in vitro ADME systems. A strong understanding of in vitro and in vivo DMPK principles.
Desirable Good organizational, collaboration, communication skills and flexibility are important assets. 0 – 4 years previous pharmaceutical industry experience with experience in drug discovery and candidate selection. Familiarity with PK/PD and PBPK basic methodology and principles. Familiarity with commonly encountered modeling and simulation packages (e.g. WinNonlin, Simcyp, Gastroplus, ADAPT, SAAMII ). In addition, familiarity with software packages such as MATLAB, SIMBIOLOGY, Python, R or other similar programs is highly desirable.
|11/19/18||Associate Scientist-DMPK Bioanalytical/Mass Spectrometry||Individual contributor||South San Francisco, California|
We are seeking an exceptional individual for an Associate Scientist position within the small molecule bioanalytical group of DMPK Department at Genentech. The successful candidate will have strong background in Bioanalytical Mass spectrometry (LC-MS/MS and LC-HRMS) with hands on experience and proven ability to independently design, develop and routinely employ bioanalytical methods for the quantitative and qualitative analysis of endogenous small molecule metabolites (biomarkers), new chemical entities and their metabolites in various biological matrices. Candidates should also have a very good understanding of various small molecule metabolomics workflows, instrumentation and experiment design. This role also requires a good understanding of preclinical and clinical ADME, endogenous metabolic pathways to work collaboratively with teams from research to drug discovery and development. The candidate will work as a member of the metabolomics/bioanalytical group and will be responsible for method development, sample preparation (LLE, SPE, and PP) and data acquisition on various platforms such as QTRAPs, triple-quadrupole instruments, high-resolution mass spectrometers (QTOF, Orbitrap QE series), and data processing using Xcalibur, Compound Discoverer, Tracefinder, Analyst/Multiquant, and XCMS+. The candidate should be able to assist in troubleshooting when instrument or assay problems arise. Other responsibilities will include metabolomics data visualization and statistical analysis, electronic laboratory notebook keeping and communication of results to project teams.
Requirements: Ideal candidate is preferred to have a PhD in chemistry, biochemistry, or other equivalent degree with relevant experience of 0-2 years. Experience with metabolomics workflows is preferred. Candidate should also possess excellent oral and written communication skills.
|11/19/18||Senior Global Project Manager||Individual contributor||South San Francisco, California|
Considering local candidates only.
The Global Project Manager (GPM) is a core member on the Lifecycle Team that sets strategy and delivers transformative medicines to patients faster and more effectively. The GPM is a strategic partner with their team leaders and plays a critical role in proactive planning, execution and optimizing timelines/resources through excellence in project management.
This position reports directly into a Group Leader/Associate Director in the PPS-PM group.
Successful candidates will have a minimum of 10 years of relevant experience, including a minimum of 7 years supporting cross-functional teams in a scientific environment required. They can anticipate the needs of the project/business and proactively drive teams with portfolio context in mind. They have the ability to operate effectively in situations of ambiguity and guide teams through challenges, simplifying/distilling complex issues and influencing change in a skillful and mindful way.
Bachelor's degree required; advanced degree preferred.
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