The Matsumoto lab, within the Structural Biology Department at Genentech, is seeking an innovative postdoctoral fellow to pursue engineering and structural characterization of immunoglobulins and their interactions with various cellular receptors and antigens. The postdoc will use protein engineering paired with X-ray crystallography and/or cryo-electron microscopy (cryo-EM) to explore various immunoglobulin formats for technology development and potential therapeutic applications. He/she will structurally characterize complexes of immunoglobulins with their receptors to elucidate the molecular mechanisms of recognition and understand structure-function relationships. The successful candidate will spearhead all aspects of his/her projects including antibody engineering, protein purification, biophysical characterization, and structure determination. Our department has state-of-the-art crystallography and cryo-EM facilities along with directed evolution platforms for protein engineering. This is a unique postdoc opportunity to pursue cutting-edge technology development and publication-oriented basic research in a highly collaborative, industrial setting.

Who you are:

The successful candidate will be a highly motivated and detail-oriented researcher, driven to solve complex scientific problems, and able to work both independently and in a collaborative environment. Strong oral and written communication skills are required. Candidates must have a PhD. in structural biology, biochemistry, molecular biology, or a related field. Expertise in protein purification, biophysical characterization, and structure determination by X-ray crystallography and/or single-particle cryo-EM is required, as evidenced by a strong record of first-author publications in top peer-reviewed journals. Experience in protein engineering and directed evolution techniques, such as phage display, along with biophysical characterization methods for protein-protein interactions, such as surface-plasmon resonance (SPR) or bio-layer interferometry (BLI), are a plus.

More information on the Matsumoto Lab:

www.gene.com/scientists/our-scientists/marissa-matsumoto

More information about the Genentech Postdoctoral Program:

www.gene.com/careers/academic-programs/postdocs

Relevant publications:

Kumar N. et al. (2020) Structure of the Secretory Immunoglobulin A Core. Science 367(6481):1008-1014. DOI: 10.1126/science.aaz5807

Kumar N. et al. (2020) Structure of the Human Secretory Immunoglobulin M Core. bioRxiv DOI: 10.1101/2020.09.10.291138

Lombana T.N. et al. (2019) Production, Characterization, and in vivo Half-Life Extension of Polymeric IgA Molecules in Mice. MAbs 11(6):1122-1138. DOI: 10.1080/19420862.2019.1622940

Yau R.G. et al. (2017) Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control. Cell 171(4):918-933.e20. DOI: 10.1016/j.cell.2017.09.040

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#postdoc

Seeking an independent researcher for a Postdoctoral training position in the Dixit lab to study the biochemical basis of  innate immunity.

Candidate should possess a doctoral degree and have a strong background in either biochemistry, structural biology or molecular immunology. Qualified candidates must have at least one first author paper published or accepted in a peer-reviewed journal.

More information about the Genentech Postdoctoral Program: 

www.gene.com/careers/academic-programs/postdocs

More information about the Dixit Lab:

www.gene.com/scientists/our-scientists/vishva-dixit

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#postdoc

Location: South San Francisco

Start Date: Fall 2020

Term: 1 year

Hours: 40 hours/week

Job Description:

Genentech’s Clinical Development organization is structured by therapeutic area and is responsible for developing and executing the late development (Phase Ib – III) clinical strategies and plans that deliver medically-differentiated therapies that provide meaningful improvement to patients. 

Delivering superior clinical research requires close collaboration between academic and industry professionals.  The Genentech Clinical Research Fellowship program entails a collaboration between academic institutions and Roche-Genentech, offering experienced MD fellows interested in a career in clinical research, a one-year experience in this area. 

Roche, a world leader in clinical research, has generated large clinical databases from multiple randomized clinical trials and registries. Your own exceptional talents can help take us further, building on this data while giving you the opportunities you're seeking to propel your career.

Diverse candidates are encouraged to apply. 

Responsibilities:

These would mainly consist of, but are not limited to:

 Clinical Development Team  - Ophthalmology 

• Analyzes and interprets data from clinical studies

• Is a member of the relevant Clinical Science Team (CST)

• Participates as an ad hoc member in sub-teams (e.g., Study Management Teams) relevant to assigned molecule(s)/indication(s) and supports the CST lead and overall team 

• Participates in strategic meetings (at study or project level) in order to gain a deeper understanding of the complexities and challenges of drug development

• Maintains the highest standards and levels of scientific and clinical knowledge in the specific therapeutic area(s) of assignment, providing clinical expertise in the disease area for cross functional teams

• Collaborates with a variety of internal and external partners and stakeholders, such as clinical investigators, clinicians, scientists and Therapeutic Area Experts (TAEs), as well as multidisciplinary internal groups, including other groups in PD or gRED, research, biomarkers development, regulatory, business development, commercial operations, legal, etc. providing clinical support across all relevant studies and programs 

• Consistently complies with all governing laws, regulations, Roche Standard Operating Procedures (SOPs) and other guidelines

Clinical Fellowship Project 

• Secures a mentor from their academic institution (if applicable)

• Designs clinical research projects in his/her area of interest 

• Partners with Biostatistics and Programming in order to generate the necessary analyses plans for the research projects

• Is responsible for generation of abstracts or manuscripts for publication derived from the clinical research findings and presents the research findings at key conferences and other specialty meetings

• Participates in relevant internal and external Genentech meetings related to the projects

• Completes the research projects within the one-year program

• On an ongoing basis and at the conclusion of their one-year fellowship, presents his/her data to an internal peer review group

Education and Training

• With support of the Genentech mentor, develops an educational project plan to improve his/her knowledge base on Drug Development

• Participates in regular therapeutic area meetings on a variety of clinical topics

• Participates in additional relevant Roche-Genentech training opportunities that arise throughout the year

• Completes the Genentech/Roche Standard Operating Procedure training modules

SELECTION CRITERIA:

Candidates for this position should hold the following qualifications, have the following experience, and be able to demonstrate the following abilities to be considered as a suitable applicant. Please note that except where specified as “preferred,” or as a “plus,” all points listed below are considered minimum requirements.

QUALIFICATIONS & EXPERIENCE:

• Experienced MD fellows, in their fellowship stage of medical subspecialty training, in major academic institutions

• Exceptional senior residents might also be considered as fellowship candidates

• Experience in generating publications and manuscripts‒ own publications track record is a plus

• Teaching background is a plus

• Fellows and their academic institutions must agree to uphold Roche-Genentech confidentiality and intellectual property contracts

• Fellows must be able to work at Genentech headquarters in South San Francisco (SSF) or be able to attend remote working calls during SSF hours. 

• Experience working with the principles and techniques of data analysis, interpretation and clinical relevance 

ABILITIES:

• Has impeccable ethics.  Demonstrates, or proven abilities to demonstrate, Roche Values

• Outstanding attention-to-detail

• Excellent project management skills: can prioritize multiple tasks and goals and ensure the timely, on-target and within-budget accomplishment of such

• Good interpersonal, verbal communication and influencing skills; can influence without authority

• Strong written communication skills

• Good presentation skills; is comfortable and effective when presenting to others, internally or externally

• Good judgment and decision-making skills; knows how to make trade-off decisions while balancing ethics and efficacy

• Works well within teams and is effective in collaborating with others internally and externally

Job Purpose:

Portfolio Safety Scientists (PCS-Sci) provide safety science and pharmacovigilance support to molecules across the Roche portfolio. As a group, they are responsible for all aspects of safety science/pharmacovigilance, with accountability being held by PCS leadership or SSLs (Safety Strategy Program Leaders) depending on the deliverable/activity.

The Portfolio Safety Scientists (PCS-Sci) supports early and late phase development activities as a member of the safety team, providing essential safety oversight and input into all aspects of study management across the entire development and marketed portfolio. In the post-market setting this may include signal evaluation, safety related activities associated with new drug applications/regulatory filings, benefit-risk assessment and safety risk management.

A PCS-Scientist (level 4) is recognized to have strong expertise in drug safety and will be expected to work with minimal oversight and apply strong self-leadership. They will bring safety expertise to interactions with internal stakeholders, Regulatory Authorities and Data Monitoring Committees and must have the ability to interact effectively in a multifunctional and multicultural team setting. The job holder will be expected to identify areas of development and complete the required training.

They may be assigned the role of “Safety Program Strategy Leader (SSL)” for one or more molecules. The SSL is the lead safety accountable for the molecule safety strategy.

Job Responsibilities:

Under the matrix leadership of the SSL and/or in collaboration with PCS colleagues

● Develop and maintain an expert understanding of the safety profile of the assigned product(s) as well as understanding of the relevant strategic context (e.g., disease under study, safety profile of competitors, mechanism of action)

● Responsible for signal detection and management activities including, but not limited to STAR maintenance, ISMP maintenance.Contribute to the review of safety assessments and drug safety reports for signals or issues (inc, product quality) or in response to Regulatory Authority requests

● Provide expert contribution to the development of the product safety strategy

● Take independent responsibility for risk management activities including preparation and maintenance of CCDS, labeling document maintenance (including IB), risk communications, RMP, REMS

● Review of clinical protocols, study reports, Investigator's Brochure (IB), informed consent form (ICF) and other related documents to ensure alignment with the safety strategy and ensure the appropriateness of risk management strategies and risk communication

● Take responsibility for safety science contributions to regulatory authority submissions (Investigational New Drug/IND applications, New Drug Applications/NDAs, Marketing Authorization Applications/MAAs, Variations, Renewals, etc.)

● Responsible for the preparation and maintenance of safety sections of the Company Core Data Sheet and/or Reference Safety Information in the IB

● Participate in and provide input for Drug Monitoring Committees (iDMC) or internal monitoring committee (IMC) meetings, as applicable

● In partnership with the SSL, support presentation of important safety issues to the Drug Safety Committee (DSC), Development Review Committee (DRC) and other internal and external review and governance committees as needed.

● May be expected to support non-molecule projects, due diligence evaluations and other projects as needed.

● Perform specialized roles with PCS. These may include, but are not limited to; functional business process owner, subject matter expert, safety committee member.

● Responsible for coordination and collaboration with vendors servicing Safety Science

Additional responsibilities, under the delegated accountability of the SSL:

● Contribute and/or lead the development of the safety components of the Target Product Profile (TPP), key claims and other lifecycle strategic planning documents (e.g., IDCP, CDP)

● Accountable for the safety components of study reports, aggregate reports and high level regulatory documents

● Acquire and contribute knowledge of relevant drug class and/or competitor safety issues. Lead development of the safety surveillance strategy, identify potential clinical safety issues and recommend appropriate safety monitoring measures

● Lead the development of scientific publications (abstracts, posters, papers) for scientific meetings/journals and approve the submissions from a safety perspective

● Enable/facilitate the transition of appropriate drug candidates from EMS to LMMS Behaviors and responsibilities

● Demonstrates behaviors consistent with Roche values and engenders confidence from senior management

● Actively emulate and role model the Roche values, culture (mindset and behavior), Roche core competencies and PD/PDS strategy and drive for similar performance across relevant team

● Understands how safety activities contribute to company development and commercialization goals and takes measures to maximize safety value to the organization

● Demonstrates independence and high competence in the conduct of all safety science responsibilities

● Establish and maintain collaborative working relationships with all key stakeholders, and internal and external customers and ensure the same across relevant teams

● Consistently comply with all governing laws, regulations, QMS, Roche standard operating procedures (SOPs) and other guidelines

● Develop and maintain knowledge of the pharmaceutical industry and drug development, including a comprehensive knowledge of pharmacovigilance activities and requirements

● Acts independently and with minimal supervision to manage safety responsibilities on study teams and in activities supporting safety science

● Trains and mentors more junior PCS scientists

● Proactively takes on responsibility for complex deliverables

● Takes on team leadership responsibility in order to manage and complete medium and high priority projects

● Seen by peers and cross-functional colleagues as an expert in many safety science activities

● Contributes to embedding the agreed organizational models, and the necessary mindsets

● Leading self and others, often influencing without authority, to deliver outcomes.

● Brings critical, systematic thinking to shape current issues and opportunities into meaningful, deliverable actions.

● Willing to challenge embedded behaviors/mindsets, in order to bring new and agile approaches to ways of working, and/or to improve quality and efficiency.

● Holds themselves and peers accountable for their behaviors and actions

Education, Skills and Experience:

Minimum Qualifications: Qualified healthcare professional or Life Sciences graduate.

Preferred Qualifications: A relevant postgraduate qualification (e.g. PHD/MSc in a Life sciences discipline; PharmD or other post-graduate health professional qualifications) would be advantageous

● Safety Director: 6 or more years of drug development experience in the pharmaceutical or related industry including at least 3 years in drug safety

● The ability to demonstrate a broad understanding of the scientific aspects of safety, PV and clinical/patient risk management (e.g. via demonstrable knowledge of the application of GVP, GCP & CTR requirements) is essential.

● Demonstrated ability to lead and influence, with and without authority, in a global matrix environment.

● Excellent written and verbal communication skills.

● Proven success in creating and sustaining strong relationships with internal and external business partners across an organization to create positive partnerships.

● Evidence of proactive, structured thinking with the ability to rapidly respond to an evolving and complex environment.

● Apply complex data analysis / statistical methods to evaluate, interpret and present scientific data with clarity

● Strong presentation skills, effective at summarizing and presenting the key considerations and decision points

● Ability to effectively train others on departmental practices and processes

● (For roles in China) Fluent in Mandarin and English

• Participate and thrive in an interactive, purpose driven culture

Who you are

A leader with a strong scientific and clinical background who has a passion for making medical progress for people affected by MS. You are looking for a company where you have the opportunity to positively impact peoples’ health, and where a job title does not define who you are professionally but is the starting point of what you can achieve.

Qualifications, Experience and Skills

• Board Certified physician with clinical experience in Neurology/ MS is preferred

• Minimum 5-10  years of relevant clinical / medical pharmaceutical/biotechnology industry experience

• Experience or relevant knowledge of pre-approval drug development trials and/or post-marketing medical evidence generation, including expertise in controlled and observational study designs, data analysis, and clinical/health economic interpretations

• Understanding of the US health care environment including the payer landscape, evidence-based medicine tools and practices, and health technology assessments

• Ability to navigate complex and challenging situations and flex and thrive in an ambiguous environment. The position is located in South San Francisco but the candidate may be remote but would be required to spend time in the home office. The position may requires up to an additional 35% time traveling.

CMG Operating Principles

I put the patient first, always

I am obsessed with meeting customer needs

I act on behalf of the whole company, not just my team

I am inclusive

I have a growth mindset

I act with urgency

I am accountable

I radically simplify and prioritize for impact

I follow the science

I build our reputation

External Link: https://www.gene.com/careers/commercial-operating-principles

Roche is an equal opportunity employer.

The Cancer Immunology Department is seeking a highly motivated Senior Scientific Researcher to perform discovery research at the interface of human genetics, immunology and cancer. The successful candidate will lead research projects to implement and apply statistical genetics methods and integrate additional data modalities such as RNA-seq or tumor genomes to identify and enhance our understanding of novel therapeutic targets and biomarkers, and will be expected to make intellectual as well as technical contributions to the team.

Responsibilities: 

• Perform disease-oriented research with a focus on reverse translation, utilizing both clinical trial data and external resources (academic collaborations, population biobanks)
• Independently design, execute, analyze and present studies to various forums within the department and across the wider Research organization.
• Collaborate closely with internal as well as academic collaborators

Genentech provides an exceptional research environment composed of internationally recognized leaders as well as state of the art core facilities with cutting edge technologies and computational resources to support all research activities. You will have the opportunity to participate in the discovery and investigation of drug targets, and contribute to a better understanding of individual differences in patients’ responses to cancer immunotherapy. We provide a highly collaborative community, and you will work closely with other researchers in the areas of Cancer Immunology, Human Genetics, Bioinformatics and Statistics.

Qualifications:

The successful applicant will have a PhD in human or statistical genetics or a related field and experience in an academic or industry setting. Candidates must have a documented record of professional achievement in the form of impactful publications, and must be familiar with statistical association (e.g. Plink, SAIGE) and fine-mapping approaches (“variant-to-function”). Expertise in the use of a high-level programming language such as R (preferred) or Python for statistics and computational biology is required, as well as familiarity with UNIX and high-performance computing environments. Experience in differential expression analyses is a plus. Excellent oral/written communication skills, creative problem-solving flexibility, and the ability to integrate detailed analyses into a larger disease-oriented context will be expected.

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Genentech CMG Finance is excited to hire a Senior Director to lead the OMNI Finance team and provide ecosystem support for the Mid-Atlantic (Ecosystem) Region.

The Senior Director reports into the Genentech CFO, is an engaged member of the Genentech Finance Community and a member of OMNI Therapeutic Area (Squad) Leadership. The Senior Director will be a strong financial and strategic thought partner to the OMNI BU SVP and Mid-Atlantic Regional (Ecosystem) VP. The OMNI BU represents 8 Squads, with ~ $14B in net sales and total OpEx of ~$2.3B.



This position is preferably located in South San Francisco, CA, however, we welcome candidates from all US territories as working remotely is a possibility.



Key Position Responsibilities:

• Lead the OMNI Finance Team, set the vision, coach the Squad CFOs in addition to other CMG Finance/business priorities as needed

• Coach and mentor Finance team members across the CMG “Tripod” (Squads (TAs), Functions, and Customer Engagement (Ecosystems))

• Coach and mentor the Medical Finance Team

• Lead the strategic planning, business planning, economic analysis, people development, and overseeing and participating in operational activities

• Dependable in and comfortable with an environment of emergent change

• Act as an economic advisor to stakeholders by providing financial expertise and context to support stakeholders in decision-making, trade-off discussions, business cases, and strategic context

• Provide financial transparency, analytics & insights while working with business partners and Finance

• Assist on various ad hoc financial requests pertaining to CMG Organization (US Leadership Team) as needed

• Enable and drive best practice sharing across areas

• Identify and deliver opportunities to simplify and improve processes and systems

• Capacity and desire to actively operate at all levels - be a player coach - leading by example

• Actively contribute to the Therapeutic areas (Squads) by taking on a leadership role as Squad CFO

• Member of CMG Finance Leadership Team and partner with the gFLT to lead and develop the Genentech Finance Organization

Competencies Required:

• Mindset and behavior that exhibit enterprise thinking and entrepreneurship

• Teamwork & Collaboration - Foster a sense of belonging and community for the team

• Communication & Change Management

• Inspiring and Influencing

• Technical and Business Expertise: in addition to the business and financial acumen, create an integrated and unified strategy to meet business and customer needs while delivering on results

• Strategic Agility

• Early adopter of Agile mindset / behavior consistent with CMG Transformation

Experience Required:

• Bachelors’ degree in business, healthcare management, life sciences, finance or related disciplines; MBA is preferred, CA/CPA or related graduate degree in accounting or finance is a plus

• Minimum 15+ years of relevant financial experience; ideally some exposure to U.S. Commercial healthcare market

• Excellent communication and presentation skills with extensive experience interacting with senior-level management

• Track record of outstanding partnership and proactivity in consulting to senior management

• Experience in partnering with business functions, with a strong affinity and drive for connecting at different levels of the organization

• Strong analytical skills, structured thinking and focus on results as well as ability to deliver high quality within tight timelines

• Proven process management skills with experience leading a complex, cross-functional processes

• Proactive approach, open-minded and flexible attitude

• Excellent influencing skills to integrate various stakeholders’ needs while ensuring alignment with overall Finance processes and guidelines

Main Purpose of the Position:   

The Environment, Health and Safety (EHS) Strategy & Business Operations leader will head several business critical areas that are core to the effective performance of the EHS department, including:  

• Financial and operational management

• EHS management system and IT systems

• Communications and training

• Process improvement, auditing and governance

• Portfolio management

This critical position reports directly to the Senior Director of EHS and serves as a member of the EHS leadership team. Directly reporting to this position will be a small team. 

This leadership position will be accountable for partnering with the Senior Director of EHS and EHS leadership team to develop, align and implement EHS multi-year strategies and goals that reflect EHS’ role as steward for the Genentech culture. This position will also be pivotal in ensuring EHS creates and realizes an operating model that makes the customer experience easier and increases the influence and impact of EHS as a strategic partner to the business in their risk decisions and in creating a safety culture throughout Genentech.  

This role will be a member of the Site Services Business Manager Forum and will work closely with the Site Services Director of Strategy and Business Operations as well as other Site Services leaders in functions responsible for protecting our right to operate and ensuring business continuity.

This individual will also need to build strong relationships with internal Roche functions and external regulatory agencies, including those who do audits of Genentech’s business.

The ideal candidate will be a passionate advocate for a safe, healthy and sustainable work environment and bring strategic consulting experience in leading change in complex, highly regulated businesses that are shifting to more agile ways of working.

Job Duties/Responsibilities: 

• Drives the rhythm of the business, business planning, operations management, metrics dashboard and communications, including leading the process with an enterprise-wide mindset and being a strong voice on the EHS leadership team in developing high impact multi-year strategies and goals that align to the Site Services and Genentech strategies, goals and business needs.  Plans and directs all financial and operational activities for the Senior Director of EHS.  

• Develops and/or mentors EHS LT members to develop business cases for investment decisions, new Roche Safety, Health & Environment (SHE) requirements, and changes to programs. Leads the transformation of providing timely, accurate and relevant EHS data to enable business decisions. 

• Develops and manages, as a portfolio, the EHS pipeline of projects with a focus on interdependencies to ensure awareness of critical paths, alignment of resources, and alignment to the EHS business strategy.

• Lead EHS LT budget reviews and long range forecasts, including ownership and decision making on their department budget. Oversee EHS Internal Business Review data collection and presentation development, including content for reviews with the EHS LT/ELT and with Site Services Leadership as appropriate.

• Lead and coordinate EHS readiness for Roche Corporate SHE audits and actively manage the closure of corrective actions and preventive actions (CAPAs).

• Serve as a thought partner and strategic advisor to the Senior Director of EHS on critical business, client and/or program issues, as well as evolving the EHS culture.  

• Drive necessary changes within EHS to ensure the client experience is simple and delivers high value to the business--and support the Senior Director of EHS and EHS LT peers in ensuring the EHS operating model is effective. Be a visible and dynamic champion of EHS and contribute to EHS having greater impact and influence as a strategic partner to the business in their risk decisions. 

• Lead the development and realization of the EHS technology and informatics/IT systems strategy. Serves as a single accountable decision maker for these strategies. 

• Ensure effective utilization of data analytics and dashboards to enable business decisions both within and outside of EHS. 

• Own, as the single accountable decision maker, and evolve the EHS management system to ensure better and consistent control of major business processes, regulation of successful working practices, increased customer satisfaction, and reduction of risk.  Evolve the EHS compliance assurance program to ensure our programs and processes are monitored for compliance/conformance to regulations and company requirements while adding value to the business.  

• Create high impact communications strategy for the Senior Director of EHS for internal and external audiences, particularly for executive updates and decisions.  Partners with Site Services SBO Communications when a broader Genentech audience needs to be reached.

• Lead the development and prioritization of the EHS training portfolio, working in collaboration with the Site Services Learning & Development team.  Single accountable decision maker for EHS training strategy.

• Develop a team of professionals who deliver expertise and practical solutions to EHS and our clients.  Ensure EHS has the capabilities in people, processes and technologies to meet emerging and current client business needs.  Serve as mentor and coach for their team and the EHS organization and help create an environment that enables people to grow and succeed. 

• Provide leadership within the Site Services Business Manager Forum and represent EHS priorities while wearing a Site Services leader hat and enterprise mindset.  Partner with other Business Managers and Site Services leaders on key initiatives.

• Leverage and champion relevant best practices and maintain connectivity and build relationships, particularly with other business operations professionals internally and externally. 

• May be required to serve as a Safety Officer during disaster/emergency response and recovery efforts.  May be required to serve as an EHS advisor (technical expert) for the emergency response team during company emergencies. 

Competencies Identified for Success: 

• Experience facilitating the development and realization of strategies, ideally with a focus on services and programs that have led to significant improvements in performance. Balances risk with practical business needs for speed and simplicity.

• Proficient developing business cases/ROIs, managing budgets (of at least $10M) and operational services.  Brings the business and financial acumen to facilitate investment decisions. Skilled at analyzing data and translating into high-impact recommendations on how to reduce risk and improve sustainability. 

• Broad experience managing efficient operations, including ensuring effective business process and metrics-driven alignment to achieve goals. Excellent planning and prioritization skills with the ability to multitask and adapt in a dynamic environment. Proactive orientation.  

• Highly effective team player and collaborator. Track record of partnering with and engaging others to realize change. Strong comfort working in a matrix environment, leveraging expertise across functions and building local and global networks.  

• Proven ability to successfully coach, develop, and lead a team of professionals, including experience directly managing employees, consultants and contractors. Able to inspire and motivate teams. Strong emotional intelligence and a collaborative approach is critical. Passion for developing talent and building strategic consulting capabilities.

• Strong executive presence and resonant communication skills.  Ability to clearly articulate services and programs in a way that resonate with key stakeholders. Ability to frame and deliver presentations/communications at executive level, including effective use of insights from data to influence and inspire people to care.  Experience leveraging a variety of communication channels, including social media and apps.

• Exceptional strategic consulting skills balanced with a drive for execution: deeply listens, thinks with an enterprise-wide mindset.  Demonstrates strong judgment in decision making and quickly gains trust.  Able to consider the best solution/outcome for  Genentech.  Responds with agility in navigating complex business and organizational dynamics.

• Skilled at seeing opportunities from challenges.  Track record of being resilient and adaptable in navigating organizational resistance and influencing others to adopt new behaviors and approaches.  Visible and dynamic champion for EHS.

Qualifications: Education, Experience, Knowledge and Skills:

(Minimum requirements)

• Education:  BS in business, finance, engineering, life sciences/health or related field; MBA preferred

• 12+ years business/operations experience preferably in increasingly more responsible roles. 8+ years working on/with leadership teams in managerial/leadership roles in commercial, manufacturing or lab-based functions.

• Minimum of 4 years large scale project/program management and expertise improving business processes.  Practical experience with Lean/Six Sigma business process improvement methodology, including a belt certification, is strongly preferred. Experience with agile methodology is desirable. A certification as a project management professional (PMP) is desired.

• At least 5 years leading multi-disciplinary teams and directly managing people. Experience leading employees, contractors and third party service providers is a must. 

• Experience managing a significant budget, meeting financial targets, and driving cost savings. Demonstrated success meeting or exceeding performance metrics. 

• Familiarity with OSHA, EPA, DOT, NIOSH, FDA and other regulatory requirements applicable to cGMP and non-GMP environments.  Experience in pharmaceutical, biotech, medical device or high tech industries is desired.

• This position is not eligible for relocation

Genentech seeks a talented and highly motivated computational biologist/bioinformatics scientist to pursue reverse translational data-driven projects in close collaboration with our Oncology Biomarker Development and Cancer Immunology Departments.

Recently, exciting developments at Genentech and elsewhere have demonstrated the potential of leveraging the human immune system for effective and durable control of cancer. Our extensive high-dimensional molecular characterization of samples from cancer immunotherapy clinical trials provide an outstanding opportunity for rapidly taking clinical insights back into the laboratory.

The primary focus of this position is on deep exploration of high dimensional clinical trial datasets, with the goal of translating findings into testable hypotheses about the variability in human immunotherapy response. This high-impact work informs new investigational immune-based cancer therapies and combinations.

Applicants should be able to work comfortably on an interdisciplinary team, have a strong desire to carry out data analysis and integration across various domains (High-throughput Transcriptomic, Genomic, Proteomic, Epigenomic data), and apply best-in-class algorithms — or develop new algorithms — that directly address the motivating biological and clinical questions. Regular publication of scientific results is strongly encouraged. Finally, applicants should be able to effectively present complex results in a clear and concise manner that is accessible to a diverse audience of quantitative, experimental, and clinical scientists.

Who you are

• You have a PhD in Computational Biology, Biostatistics, Bioinformatics or similar, with a strong publication record. Alternately, you have a PhD in Immunology, Molecular Biology, etc. combined with a very strong record of high-throughput data analysis, supported by publication in this area.

• You have a solid understanding of the relevant concepts in cancer biology and genetics, or in immunology. You also have enthusiasm for learning more.

• You have postdoctoral experience in basic or translational research either in an academic or industry setting with a record of publication in lead positions.

• You have a broad experience with data generated by one or more high-throughput molecular assays: Next-generation sequencing, flow cytometry, etc. If you have additional experience with single-cell assays (e.g., single-cell RNA-seq or CyTOF) it is a significant plus.

• You understand the statistical principles behind current best practices in high-throughput molecular data analysis.

• You have a strong experience in the use of a high-level programming language such as R or Python for complex data analysis.

• You have exceptionally strong communication, data presentation and visualization skills.

• You enjoy working both independently and collaboratively, and feel comfortable to handle several concurrent, fast-paced projects.

What to expect from us

• A highly collaborative and dynamic research environment where we aim to translate our understanding of cancer biology and immunology to develop personalized therapies and diagnostics to transform clinical practice to benefit patient health.

• Access to clinical data sets and samples.

• Access to state-of-the-art technologies and pioneering research.

• Participation in seminar series featuring academic and industry scientists.

• Campus-like lifestyle with a healthy work-life balance.

• Mentored opportunities to further develop professional skills.

#LI-GL1

#bioinformatics

#computationalbiology

Genentech seeks a talented and highly motivated computational biology / Bioinformatics scientist to pursue reverse translational data-driven projects in close collaboration with our Cancer Immunology and Oncology Biomarker Development Departments.

Recently, exciting developments at Genentech and elsewhere have demonstrated the potential of leveraging the human immune system for effective and durable control of cancer. Our extensive bulk and single-cell RNA-seq characterization of samples from cancer immunotherapy clinical trials provide an outstanding opportunity for rapidly taking clinical insights back into the laboratory.

The primary focus of this position is the identification of signals in single-cell and bulk RNA-seq data that are associated with the variability in human immunotherapy treatment response. This will form the basis to further investigate the mechanistic basis for the clinical observations.

Applicants should be able to work comfortably on an interdisciplinary team, have a strong desire to carry out data analysis and integration across various domains (High-throughput Transcriptomic, Proteomic, Epigenomic data), and apply best-in-class algorithms — or develop new algorithms — that directly address the motivating biological and clinical questions. Regular publication of scientific results is strongly encouraged. Finally, applicants should be able to effectively present complex results in a clear and concise manner that is accessible to a diverse audience of quantitative, experimental, and clinical scientists.

Who you are

• You have a PhD in Computational Biology, Biostatistics, Bioinformatics or similar, with a strong publication record. Alternately, you have a PhD in Immunology, Molecular Biology, etc. combined with a very strong record of high-throughput data analysis, supported by publication in this area.

• You have a solid understanding of the relevant concepts in cancer biology and genetics, or in immunology. You also have enthusiasm for learning more.

• You have postdoctoral experience in basic or translational research either in an academic or industry setting with a record of publication in lead positions.

• You have a broad experience with data generated by one or more high-throughput molecular assays: Next-generation sequencing, flow cytometry, etc. If you have additional experience with single-cell assays (e.g., single-cell RNA-seq or CyTOF) it is a significant plus.

• You understand the statistical principles behind current best practices in high-throughput molecular data analysis.

• You have a strong experience in the use of a high-level programming language such as R or Python for complex data analysis.

• You have exceptionally strong communication, data presentation and visualization skills.

• You enjoy working both independently and collaboratively, and feel comfortable to handle several concurrent, fast-paced projects.

What to expect from us

• A highly collaborative and dynamic research environment where we aim to translate our understanding of cancer biology and immunology to develop personalized therapies and diagnostics to transform clinical practice to benefit patient health.

• Access to clinical data sets and samples.

• Access to state-of-the-art technologies and pioneering research.

• Participation in seminar series featuring academic and industry scientists.

• Campus-like lifestyle with a healthy work-life balance.

• Mentored opportunities to further develop professional skills.

#LI-GL1

#bioinformatics

#computationalbiology

Who We Are

At Roche, 80,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity, and diversity, and on seeing each other’s differences as an advantage. To innovate healthcare, Roche has ambitious plans to keep learning and growing – and is seeking people who have the same goals for themselves.

That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

The Basel Branch Roche Diagnostics International, Diabetes Care employs over 100 people and is the headquarter of the business unit Diabetes Care. As a world-leading supplier of system solutions for patients with Diabetes, the products provide health information to medical decision-makers pivotal for early identification, diagnosis & monitoring.

• Participate and thrive in an interactive, purpose driven culture

Who you are

A leader with a strong scientific and clinical background who has a passion for making medical progress for people affected by NMO and MS. You are looking for a company where you have the opportunity to positively impact peoples’ health, and where a job title does not define who you are professionally but is the starting point of what you can achieve.

Qualifications, Experience and Skills

• Board Certified physician with clinical experience in Neurology/ MS is preferred (other non-MD experienced candidates also considered)

• Minimum 5-10 years of relevant clinical / medical pharmaceutical/biotechnology industry experience

• Experience or relevant knowledge of pre-approval drug development trials and/or post-marketing medical evidence generation, including expertise in controlled and observational study designs, data analysis, and clinical/health economic interpretations

• Understanding of the US health care environment including the payer landscape, evidence-based medicine tools and practices, and health technology assessments

• Ability to navigate complex and challenging situations and flex and thrive in an ambiguous environment. The position is located in South San Francisco but the candidate may be remote but would be required to spend time in the home office. The position may require up to an additional 35% time traveling.

CMG Operating Principles

I put the patient first, always

I am obsessed with meeting customer needs

I act on behalf of the whole company, not just my team

I am inclusive

I have a growth mindset

I act with urgency

I am accountable

I radically simplify and prioritize for impact

I follow the science

I build our reputation

External Link: https://www.gene.com/careers/commercial-operating-principles

Roche is an equal opportunity employer.

Provide technical leadership to an onsite team of employees in aligning goals and ensuring targets are met. Ensure efficient and effective delivery of operational plans based on agreed IT processes, standards and tools.

Communication – communicates functional vision/roadmap and departmental goals and work to assure employee buy- in and acceptance.

Data Centers Americas provided power, rack space, cooling, and physical network cabling to Genentech’s IT Infrastructure in Hillsboro and other sites. The role of Data Center Manager is to provide technical ability to all onsite data centers to complete support and work requests (Allocate/install rack space, hardware  installs, network cross connects and hand off’s, rack power installation, out of band console support, remote smart hands/eyes, access & environmental support), ensuring efficient and effective delivery of operational plans based on agreed IT processes, standards and tools. This role will work in conjunction with the rest of the Compute, Storage, and Cloud Services team to ensure hosted systems deliver the expected uptime and performance requirements to our global user base.

Data Analytics – Use Data Analytics best practices to review Incident Management, Data Center Information Management (DCIM) and Managed Services data to discover trends and opportunities for service improvement. 

DCIM Administration – Function as an expert user in use of and implementation of DCIM tools. Accountable for proper functioning and upgradeability of the tool.

Operational Support – Responsible for the day to day operations and maintenance of data center infrastructure. Responsible for driving the completion of service requests, incident, and problem tickets. Supports an environment of teamwork within our area and across the wider IT area. Brings concerns to the Data Centers Americas Team Lead. Drives efficiency by utilizing globally defined best practice processes for IT operations. Follows defined working processes and standards in the execution of daily duties and job functions. Understands and follows local Finance rules to support a balanced budget for the local site. Reviews trends of IT and data center infrastructure equipment, evaluates impact and potential requirements for data centers. Ensures that Data Center capacities are used in the most economical and ecological way.

DC Strategy – supports the definition and implementation of Data Center strategies and plans. Supports projects related to data centers, data center consolidation and operations.

Data Center Security and Safety – ensures that Data Centers are operated in a controlled manner based on clearly defined, agreed and monitored security and safety standards.

Data Center Facilities and Infrastructure Management – supports Data Center facilities and infrastructure by considering all relevant capacity, security, safety, environmental and financial aspects to ensure they are operated in an economical and ecological way.

Manual Operational Support for IT Infrastructure – actively supports the reduction of manual interventions on IT infrastructure by analyzing current situations and documenting impact. Challenges relevant organizations and projects to eliminate technologies which require frequent manual intervention. Plans and performs manual interventions on IT infrastructure as defined and agreed.

Change Management – coordinates and schedules change requirements between IT, facilities and business requirements. Proactively assesses impact on data center and proactively discusses IT infrastructure plans/projects which might influence DC space and energy consumption with all relevant parties.

Quality – ensure permanent inspection readiness of Data Centers. Responsible for maintaining and continuously improving the quality system and achieving quality objectives through daily actions.

KNOWLEDGE/ SKILLS/ATTRIBUTES: The minimum education, knowledge, experience, skills and attributes required to perform the essential functions of this position.

• Bachelor’s degree in Engineering or business field or equivalent work experience

• 10+ years proven track record of running high performing environments in multiple technical or business domains

• Technically lead local teams

• Customer, quality, and delivery focused

• Excellent coordination and organizational skills

• Responsible and reliable

• Strong communication skills

• Inspiring and empowering leadership style

• Energy and drive to deliver through team and managed services

• International mindset with clear goal orientation

• Excellent understanding and experience concerning Data Center infrastructure

• Very good general understanding of IT technologies, support and operations

• Excellent understanding of all Data Center security and safety related aspects

• Project management experience a plus

• As required, on call outside office hours

• Flexible working hours, in case of major incidents

• Ability to travel frequently- both domestic and global

The Alliance and Partnerships Leader is responsible for managing strategic relationships with key clinical research sites and other external clinical trial access points that support early phase clinical trials. Leveraging strong alliance management capabilities, the role develops and delivers effective relationship strategies in collaboration with internal and external stakeholders. The scope of the role includes the following:

• Define and execute alliance management strategies and proactively manage activities that support the Alliance and Partnership group’s goals

• Coordinate and support cross-functional and pan-organizational committees Create and implement team strategies across Alliance and Partnerships group and other internal / external stakeholders

• Proactively manage relationship and escalation pathway for existing Alliance and Partnership group relationships

• Set and measure specific performance objectives, standards, and accountabilities for each assigned Alliance and Partnership group relationship

• Proactively and autonomously identify and manage risks and opportunities, and resolve issues that arise with Alliance and Partnership group relationships

• Identify and implement opportunities to continuously improve performance of sites Ensure Alliance and Partnership group relationships are implemented and managed according to ethical, regulatory and legal requirements

• Partner across the Alliance and Partnership group to identify opportunities and build business cases for additional collaborations

• Stay abreast of current and future industry trends

The Sr. Alliance and Partnerships Leader leverages advanced knowledge of the drug development process, advanced relationship management skills, and strong understanding of current and future industry trends to develop, drive and lead these activities.

Qualifications

The right candidate for this role will possess the following qualifications:

• Bachelor’s Degree or equivalent, preferably in a scientific or healthcare discipline 5+ years of relevant experience with knowledge of clinical operations and drug development with a focus on early development; 7+ years of experience with advanced knowledge of clinical operations and drug development is required for the senior level

• 2+ years of alliance or relationship management experience preferred

• Strong relationship management skills, including a customer centric and innovative

• approach to partnering with internal and external partners

• Understanding of the complexities within a leading biopharma portfolio

• Adept at weighing short- and long-term impact of decisions

• Demonstrated organizational management and coordination

• Demonstrated ability to operate effectively within a constantly evolving environment and willingness to embrace change

• Ability to drive and deliver on goals to achieve desired organizational results Ability to quickly learn complex organizations and create effective partnerships both within and outside of Clinical Operations

• Ability to balance the needs of multiple stakeholders with business goals          

A flexible work arrangement and remote work from a US-based location will be considered.

#LI-JM1

#LI-remote

Genentech seeks a talented and highly motivated candidate for a computational biology position in discovery oncology research. We are looking for a computational scientist who is excited about collaborating with world-class scientists with diverse backgrounds to move science and drug development forward with the goal of making a true difference for patients. 

The Discovery oncology group is focused on developing therapies targeting major pathways involved in cancer.  Our research efforts are rooted in a deep understanding of cancer genomics spanning patient data (i.e. TCGA and other data sources), internal clinical data to pre-clinical models of cancer (i.e. PDX, GEMMs, tumor cell lines). Through experimental and computational approaches, our goal is to understand the mechanistic basis of therapeutic response and resistance as well as to discover novel targets/pathways in tumors.  Additionally, we are actively looking for biomarkers that can help match our drugs to the patients that would benefit most from treatment. In our research we apply a wide variety of high-throughput data technologies and utilize many big genomic data sets from both internal and public sources to guide our studies. 

Therefore, we are looking for a candidate who is exceptionally competent with computational tools and their application to a diverse set of large-scale data but also has the biological knowledge to be able to ask the right questions and place the results in the appropriate context to effectively move research forward. 

A successful candidate will act as the bioinformatics lead on interdisciplinary teams that contribute to drug development. She/he will lead a research agenda involving the design of experiments, analysis of a wide variety of high-dimensional data and integration of results with current biological knowledge. Further, the successful candidate should be able to effectively present complex results in a clear and concise manner — to other computational scientists as well as to audiences with other scientific backgrounds. Regular publication of scientific and methodological results is highly encouraged.

Qualifications 

• PhD plus Postdoctoral training in bioinformatics, biostatistics, computational biology or similar, with a strong publication record. Alternately, a PhD plus Postdoctoral training in molecular biology, oncology, etc. combined with a very strong record of high-throughput data analysis, supported by publications in this area. 

• For Senior Scientist: Previous leadership experience in an independent position such as industrial scientist or professor, in a role that resulted in impactful insights and publications

• A very strong understanding of the relevant concepts in cancer biology and molecular biology.

• Extensive experience with data generated by high-throughput molecular assays such as next-generation sequencing, single cell sequencing, epigenomics technologies such as ChIP-Seq or ATAC-Seq, and/or high-throughput screening data such as pharmacological screening or CRISPR screening.

• An understanding of the statistical principles behind current best practices in high-throughput molecular data analysis.

• Strong experience in the use of a high-level programming language such as R (preferred), Python or Perl for complex data analysis. 

• Exceptionally strong data presentation, visualization and communication skills with computational and non-computational audiences.

• Ability to work both independently and collaboratively, and to handle several concurrent, fast-paced projects.

#LI-GL1

#bioinformatics

#computationalbiology

The Genentech Bioinformatics department seeks a highly motivated Reverse Translation Scientist/Senior Scientist to leverage computational biology to study the molecular pathways that contribute to acute respiratory distress syndrome (ARDS), including those associated with COVID-19. The successful candidate will work with colleagues in the Translational Genomics and Immunology departments to pursue the development of novel therapeutics and biomarkers related to ARDS. The successful candidate will work as a member of a highly collaborative team to design experiments, interpret data, and develop computational solutions to address underlying biological questions. The successful candidate will lead a computationally-driven research program focused on leveraging high-dimensional data from patient-derived tissue and biofluids to develop a better understanding of the molecular mechanisms driving ARDS.

Qualifications:

• You have a PhD and Postdoctoral training in Computational Biology, Biostatistics, Human Genetics, and some experience in Immunology.

• You have evidence of scientific achievements through first or corresponding author publications in peer-reviewed scientific journals.

• You are comfortable writing code in languages such as R, or Matlab, Python, etc. and have familiarity with UNIX and high-performance computing environments.

• You are able to define and lead a computational research program involving the creative analysis and integration of high dimensional datasets (e.g. single cell sequence assays, genotype or WGS data, proteomics data and CRISPR screen analysis).

• You are intensely curious about the biology of disease and eager to contribute to scientific efforts focused on understanding the molecular mechanisms underlying disease biology.

• You have basic expertise in molecular and cellular biology.

• You are able to work successfully as the computational lead in cross-functional teams that contribute to drug and biomarker development.

• You have excellent scientific communication skills: verbally and in writing; with computational and non-computational audiences; in informal 1-1 settings, team meetings, and formal seminars.

#LI-GL1

#bioinformatics

#immunology

#computationalbiology

The Immunology Bioinformatics group is seeking a highly motivated computational Scientist to engage in therapeutic and biomarker discovery efforts within our airway disease and fibrosis programs. The successful applicant will collaborate with an interdisciplinary team of research scientists to understand the molecular mechanisms involved in diseases such as asthma, chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), idiopathic pulmonary fibrosis (IPF), and cirrhosis. The ability to collaborate with a diverse group of scientists, drive an independent research program, and publish scientific/methodological papers on a regular basis are important components of this position.

Qualifications:

• Postdoctoral training or exceptional PhD experience in bioinformatics, biostatistics, computational biology, or a similar field.

• Strong scientific publication record.

• Excellent communication and data presentation skills, including the ability to present complex scientific results to a diverse audience.

• Ability to work successfully as the bioinformatics lead in an interdisciplinary team.

• Intense curiosity about the biology of disease and an eagerness to contribute to scientific efforts focused on understanding the molecular mechanisms underlying disease etiology.

• Relevant biological knowledge in immunology, airway biology, wound repair, and/or fibrotic processes.

• Deep understanding of computational techniques for analyzing high-throughput genomic and transcriptomic datasets and an interest in applying novel approaches to explore and integrate such data (whole exome sequencing, single-cell RNA-seq, ATAC-seq, etc).

• Demonstrated competence in a programming language such as R or python, experience with version control systems, and familiarity with high-performance computing environments.

#LI-GL1

#bioinformatics

#computationalbiology

Genentech seeks a motivated Bioinformatics scientist or Computational Biologist to collaborate in the development of novel therapeutics and biomarkers to be used in cellular reprogramming and regeneration, for the treatment of immunological and ocular diseases such as inflammatory bowel disease, age-related macular degeneration, and idiopathic pulmonary fibrosis. The successful candidate will work in a collaborative environment, teaming with discovery scientists to design experiments, analyze results, and prototype bioinformatics solutions to answer underlying biological questions.

Who you are:

• You have a PhD or Postdoctoral training, preferably in Bioinformatics, Computational Biology, Human Genetics, Biostatistics, or similar fields.

• First author publications in peer-reviewed scientific journals.

• You have expertise in molecular and cellular biology, preferably in the area of reprogramming or regeneration.

• You have experience working with large scale genomic data (e.g. RNA-seq, scRNA-seq, ATAC-seq, CRISPR screens, etc.).

• You are comfortable writing code in languages such as R, or, Python, MATLAB, etc. Familiarity with UNIX and high-performance computing environments.

• You are intensely curious about the biology of disease and eager to contribute to scientific efforts focused on understanding the molecular mechanisms underlying disease biology.

As a scientist you will:

• Work as the bioinformatics lead on an interdisciplinary team that contributes to drug and biomarker development.

• Use creative informatics approaches and datasets to bring insights to biological problems.

• Work closely with bench scientists to develop those insights and ideas experimentally.

• Present complex results, both verbally and in writing, to management, bioinformatics, and non-bioinformatics audiences.

• Support and drive publications in scientific, technical or medical journals.

#LI-GL1

#bioinformatics

#computationalbiology

#genomics

The Genentech Bioinformatics department seeks a highly motivated Reverse Translation Scientist to study the molecular pathways that contribute to neurological diseases including Alzheimer’s Disease and Multiple Sclerosis. Applicant will work with colleagues in Translational Genomics and Neuroscience departments to pursue novel therapeutics and biomarkers for disease areas of focus in the Neuroscience department. The applicant will lead a data-driven research program generating and leveraging high-dimensional ‘omic data from both in vitro human cell models and patient-derived tissue and biofluids.

Qualifications

• Postdoctoral training, or exceptional PhD experience, in Bioinformatics, Biostatistics, Computational Biology or similar field, including familiarity and a strong desire to work in the field of Neuroscience.

• Strong scientific publication record

• Ability to creatively analyze and integrate high dimensional datasets (e.g. single cell sequence assays, genotype or WGS data, proteomics data, CRISPR screen analysis, etc.) to generate new biological insights, and then work closely with bench scientists to develop those ideas experimentally.

• Demonstrated competence in languages such as R or Python for bioinformatics analyses.

• Experience thinking about the biology of neurological disease and eagerness to contribute to scientific efforts focused on understanding the molecular mechanisms underlying disease etiology.

• Ability to work successfully as the bioinformatics lead in cross-functional teams that contribute to drug and biomarker development.

• Excellent scientific communication skills: verbally and in writing; with computational and non-computational audiences; in informal 1-1 settings, team meetings, and formal seminars

#LI-GL1

#bioinformatics

#Neuroscience

#computationalbiology

The Genentech Bioinformatics department seeks a highly motivated Reverse Translation Senior Scientist to study the molecular pathways that contribute to neurological diseases including Alzheimer’s Disease and Multiple Sclerosis. The applicant will work with colleagues in Translational Genomics and Neuroscience departments to pursue novel therapeutics and biomarkers for disease areas of focus in the Neuroscience department. The applicant will lead a data-driven research program generating and leveraging high-dimensional ‘omic data from both in vitro human cell models and patient-derived tissue and biofluids.

Qualifications

• Desired background:

  • PhD plus Postdoctoral training in Computational Biology, Molecular Biology, Neuroscience or related field; or equivalent

  • Previous leadership experience in an independent position such as industrial scientist or professor, in a computational biology role that resulted in impactful scientific insights and publications

• Ability to define and lead a research agenda involving the creative analysis and integration of high dimensional datasets (e.g. single cell sequence assays, genotype or WGS data, proteomics data and CRISPR screen analysis), and, in close collaboration with bench scientists, the experimental development of resulting ideas.

• Experience studying the biology of neurological disease and eagerness to contribute to scientific efforts focused on understanding the molecular mechanisms underlying disease etiology.

• Ability to work successfully as the bioinformatics lead in cross-functional teams that contribute to drug and biomarker development.

• Excellent scientific communication skills: verbally and in writing; with computational and non-computational audiences; in informal 1-1 settings, team meetings, and formal seminars

#LI-GL1

#bioinformatics

#Neuroscience

#computationalbiology