Monday, Dec 15, 2003

Genentech Announces January 14 Webcast Discussion of Earnings and Other Business Results

South San Francisco, Calif. -- December 15, 2003 --

Genentech, Inc. (NYSE: DNA) will announce its 2003 4th quarter and year-end earnings on Wednesday, January 14, 2004, after the markets close.

The announcement will be followed by a live webcast at 2:15 p.m. Pacific Time of a discussion by Genentech management of the earnings and other business results. The webcast can be accessed on Genentech's web site at http://www.gene.com and will be archived and available for replay until 5:00 p.m. Pacific Time on January 28, 2004.

An audio replay of the webcast will be available beginning at 5:15 p.m. Pacific Time on January 14, 2004 through 5:15 p.m. Pacific Time on January 21, 2004. Access numbers for this replay are: 1-800-642-1687 (U.S./Canada) and 1-706-645-9291 (international); Conference ID number is 4512259.

Genentech is a leading biotechnology company that discovers, develops, manufactures and commercializes biotherapeutics for significant unmet medical needs. Sixteen of the currently approved biotechnology products originated from or are based on Genentech science. Genentech manufactures and commercializes 12 biotechnology products in the United States. The company has headquarters in South San Francisco, California and is traded on the New York Stock Exchange under the symbol DNA. For additional information about the company, please visit http://www.gene.com.