Focus on Bioinformatics

At Genentech, we take pride in our publications. Genentech scientists have a strong track record of publishing research results in open-access peer-reviewed journals. Here are programs, data file and web applications that supplement publications.

Code and Data Files

Recent Publications

Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors
Proceedings of the National Academy of Sciences of the United States of America, August 2015
A comprehensive transcriptional portrait of human cancer cell lines
Nature Biotechnology, March 2015
Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer
Nature Communications, March 2014
A resource for cell line authentication, annotation and quality control
Nature, April 2015
Regulation of Neuronal Gene Expression and Survival by Basal NMDA Receptor Activity: A Role for Histone Deacetylase 4
Journal of Neuroscience, November 2014
Activity-Induced Nr4a1 Regulates Spine Density and Distribution Pattern of Excitatory Synapses in Pyramidal Neurons
Neuron, July 2014
Dissecting gene expression at the blood-brain barrier
Frontiers in Neuroscience, November 2014
Glucagon Couples Hepatic Amino Acid Catabolism to mTOR-Dependent Regulation of ╬▒-Cell Mass
Cell Reports, November 2015
Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/╬▓Klotho Complex
EBioMedicine, May 2015
The Immunoreceptor TIGIT Regulates Antitumor and Antiviral CD8(+) T Cell Effector Function
Cancer Cell, December 2014