Chris  Siebel - Distinguished Scientist, Discovery Oncology

Chris Siebel

Distinguished Scientist, Discovery Oncology

Postdoc Mentor
"It’s a privilege to pursue compelling scientific questions within the Genentech Research community, motivated by the opportunity to enable groundbreaking therapeutics."
Years at Genentech
Publications at Genentech
Awards & Honors

Following academic training with a research focus on RNA biochemistry, I made the big decision to decline academic opportunities, switch fields, and begin a career in biotech. After negotiating the ups and downs at a couple of early-stage companies, I embraced the chance in 2005 to join Genentech and lead a collaborative effort to target the Notch signaling pathway. Contributing to a research community that combines the philosophy of “following the science” with a stellar track record of converting discoveries into medicines has proven extremely motivating. Genentech continues to feel like an exciting, rewarding and collaborative professional home.

Postdoctoral Mentor

Many factors combine to make Genentech a fantastic place to pursue postdoctoral research. The postdoc program is central to the intellectual vitality of Genentech Research, providing license to pursue compelling basic research questions and actively engage at the cutting edge of the larger scientific community. The program can boast of a longstanding tradition of top-notch science supported by close-knit connections and a collaborative culture. I feel grateful to be a postdoc mentor, knowing that the mentor-trainee interaction not only leads to scientific breakthroughs but also brings fresh enthusiasm to my research group and challenges me to grow as a scientist.

Featured Publication

Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung.

Nature, 2015, ISSN: 0028-0836

Lafkas D, Shelton A, Chiu C, de Leon Boenig G, Chen Y, Stawicki SS, Siltanen C, Reichelt M, Zhou M, Wu X, Eastham-Anderson J, Moore H, Roose-Girma M, Chinn Y, Hang JQ, Warming S, Egen J, Lee WP, Austin C, Wu Y, Payandeh J, Lowe JB, Siebel CW.