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Dennis Hu - Senior Scientist, Discovery Chemistry

Dennis Hu

Senior Scientist, Discovery Chemistry

"It’s inspiring to be surrounded by world-class Genentech colleagues on every project – I’ve learned something new from everyone here."
Years at Genentech
Publications at Genentech
Awards & Honors

I joined Genentech in 2019 after a few years working at a biotech startup. I have been a chemistry team leader or project leader for multiple small-molecule discovery programs since joining the industry, with a focus in the areas of oncology and immunology. The ability to do research with teams of world-class colleagues and drug hunters is a privilege.

I did my doctoral studies in organic chemistry at Stanford University as an NSF Fellow, MPhil by research at Cambridge on a Churchill Scholarship, and undergraduate studies at Northwestern as a Goldwater Scholar.

Featured Publication

Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.

J. Med. Chem., 2020, 63, 5398-5420.

Paul R. Leger, Dennis X. Hu, Berenger Biannic, Minna Bui, Xinping Han, Emily Karbarz, Jack Maung, Akinori Okano, Maksim Osipov, Grant M. Shibuya, Kyle Young, Christopher Higgs, Betty Abraham, Delia Bradford, Cynthia Cho, Christophe Colas, Scott Jacobson, Yamini M. Ohol, Deepa Pookot, Payal Rana, Jerick Sanchez, Niket Shah, Michael Sun, Steve Wong, Dirk G. Brockstedt, Paul D. Kassner, Jacob B. Schwarz, and David J. Wustrow*