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Don Kirkpatrick - Associate Director and Staff Scientist, Microchemistry, Proteomics & Lipidomics (MPL)

Don Kirkpatrick

Associate Director and Staff Scientist, Microchemistry, Proteomics & Lipidomics (MPL)

Postdoc Mentor
Staff Scientist
"All roads lead to ubiquitin."
13
Years at Genentech
63
Publications
5
Awards & Honors

I joined Genentech in 2007 after completing a postdoc at Harvard Medical School in the area of mass spectrometry proteomics. Throughout my research career time, I’ve maintained a fascination with the biochemical and cellular functions of ubiquitin and its involvement in health and disease. My role as a group leader in Discovery Proteomics is to implement new technologies for studying how proteins and post-translational modifications control biological processes.

Postdoctoral Mentor

Postdoctoral fellows in my group have the opportunity to pursue independent research projects which meld mass spectrometry technologies with mechanistic biology. The majority of projects center on the biochemical functions of ubiquitin system and their regulatory roles on cellular processes.

Featured Publication

PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network.

Mol Cell. 2020 Mar 5;77(5):1092-1106

Reichermeier KM, Straube R, Reitsma JM, Sweredoski MJ, Rose CM, Moradian A, den Besten W, Hinkle T, Verschueren E, Petzold G, Thomä NH, Wertz IE, Deshaies RJ, Kirkpatrick DS.