My lab’s mission is to develop in collaboration with various groups across our research organization transformative drug delivery technologies through innovations in bioconjugation. We have active projects aimed at the development of novel conjugation methods to generate more homogeneous antibody-drug conjugates (ADCs), linker technologies to more controllably and selectively release bioactive small molecules in diseased tissues, polymer scaffolds to maximize the number of drug “payloads” that can be loaded onto an antibody, and chemical probes for understanding ADC mechanism of action.