Joe Arron - Senior Director and Principal Scientist, Immunology

Joe Arron

Senior Director and Principal Scientist, Immunology

Postdoc Mentor
"We are uniquely positioned to deliver new therapies that help patients with unmet needs to live normal lives."
11
Years at Genentech
49
Publications

After completing a combined MD-PhD degree at Cornell and Rockefeller and postdoctoral studies at Stanford, I joined Genentech in 2006. My laboratory has discovered molecular bases for heterogeneity in asthma and pulmonary fibrosis, enabling the development of biomarkers predictive of clinical benefit for targeted molecular therapies.

In addition to supervising translational research in my laboratory, I am the Director of Immunology Discovery, a department of 10 laboratories responsible for target discovery and preclinical therapeutic development in inflammatory, autoimmune, fibrotic, and ophthalmic diseases.

Postdoctoral Mentor

One privilege of working at Genentech is being a part of a long tradition of top quality basic and translational research. While it is essential to do the rigorous and focused experiments necessary to develop therapeutics, it is just as essential to explore uncharted areas of biology to yield new insights that may pay off further in the future. Our postdoctoral program represents a great opportunity to take a deep dive into fundamental mechanisms of human disease. Postdocs have a lot of latitude to explore new areas and bring to bear the incredible resources and infrastructure available at Genentech. It is the best of both worlds – a postdoc can do great research and gain valuable exposure to the drug development process.

Featured Publication

Th2 and Th17 inflammatory pathways are reciprocally regulated in asthma.

Science Translational Medicine, 7:301ra129 (2015)

Choy DF, Hart KM, Borthwick LA, Shikotra A, Nagarkar DR, Siddiqui S, Jia G, Ohri CM, Doran E, Vannella KM, Butler CA, Hargadon B, Sciurba JC, Gieseck RL, Thompson RW, White S, Abbas AR, Jackman J, Wu LC, Egen JG, Heaney LG, Ramalingam TR, Arron JR*, Wynn TA*, Bradding P*.