Junichiro Sonoda - Senior Scientist, Cancer Immunology

Junichiro Sonoda

Senior Scientist, Cancer Immunology

Postdoc Mentor
"Discovering transformative medicines is not an easy task. Being at Genentech gives me courage to believe that my wildest dreams can be realized"
10
Years at Genentech
15
Publications
3
Awards & Honors

I joined Genentech in 2007 with an audacious hope to develop innovative medicines by combining my knowledge in molecular biology and animal physiology with Genentech’s cutting-edge protein engineering technologies. After 9+ years of drug discovery effort for metabolic and fibrotic diseases with some exciting progress, my group is currently studying immune-modulatory mechanisms in adaptive tissue remodeling and cancer pathogenesis.

Working at Genentech for me so far is really like living a dream as a molecular biologist; all the resources are there, and the only limit is my imagination. Genentech is an exciting and unique place where creative and ambitious minds work together to convert wild imaginations into reality.

Postdoctoral Mentor

Being a postdoc mentor expands our ability to dig deep into the mechanistic basis of complex biological systems. Addressing fundamental questions in biology using cutting-edge technologies is itself an exciting pursuit. At the same time, knowledge that spawns from pure basic science projects could give unexpected insights into drug discovery efforts.

Featured Publication

Fibroblast activation protein cleaves and inactivates fibroblast growth factor 21.

J Biol Chem. 2016 Mar 11;291(11):5986-96

Dunshee DR, Bainbridge TW, Kljavin NM, Zavala-Solorio J, Schroeder AC, Chan R, Corpuz R, Wong M, Zhou W, Deshmukh G, Ly J, Sutherlin DP, Ernst JA, Sonoda J.

Amelioration of Type 2 Diabetes by Antibody-Mediated Activation of Fibroblast Growth Factor Receptor 1.

Science Translational Medicine; 3(113)113ra126.

Wu AL, Kolumam G, Stawicki S, Chen Y, Li J, Zavala-Solorio J, Phamluong K, Feng B, Li L, Marsters S, Kates L, van Bruggen N, Leabman M, Wong A, West D, Stern H, Luis E, Kim HS, Yansura D, Peterson AS, Filvaroff E, Wu Y, Sonoda J.