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Marissa Matsumoto - Scientist, Structural Biology

Marissa Matsumoto

Scientist, Structural Biology

Postdoc Mentor
"I am honored to be able to work with the best and the brightest scientists in the industry and have the opportunity to make contributions to the development of novel therapeutics with the potential to treat significant unmet medical needs."
7
Years at Genentech
13
Publications
1
Awards & Honors

I came to Genentech as a Postdoctoral Fellow in the Antibody Engineering department. It was fascinating to have an insider’s view into the drug discovery process and witness groundbreaking basic research being performed at the forefront of the biotechnology industry. Thus, when I was offered the opportunity to become a Scientist at Genentech I was thrilled. I initially joined the Protein Chemistry department where my group focused on large molecule drug discovery efforts through protein engineering, purification, and characterization of challenging antigens and therapeutic antibodies. I later joined the Structural Biology department and the focus of my group expanded to include protein structure determination to support both small and large molecule drug discovery. We utilize a combination of protein engineering, X-ray crystallography, and single-particle cryo-electron microscopy (cryo-EM) to enable structure-based drug design for unmet medical needs across oncology, immunology, and neurobiology.

Postdoctoral Mentor

The Genentech Postdoctoral Program offers a unique opportunity to carry out cutting-edge basic research in an industry setting. You are surrounded by leading experts in the field and have access to the latest technology and instrumentation. The discoveries made by Postdoctoral Fellows often are the spark for new therapeutic targets or technology developments. As a former Genentech Postdoctoral Fellow, I have first-hand experience of how transformative the program can be for developing scientists and am excited to now be a mentor involved in training of the next generation of scientists.

Featured Publication

Structure of the Secretory Immunoglobulin A Core

Science. 2020;367(6481):1008-1014. DOI: 10.1126/science.aaz5807

Kumar N, Arthur CP, Ciferri C, Matsumoto ML