Mark S. Wilson
Distinguished Scientist, Immunology
"Set your scientific GPS coordinates, expect the unexpected, get moving and make it happen."
After very enjoyable graduate school training with Rick Maizels in Edinburgh, UK and a postdoctoral fellowship with Tom Wynn at the National Institutes of Health (NIH), Bethesda, USA, I established my own research group at The National Institute for Medical Research (NIMR) in Mill Hill, London, in 2010. As my lab grew and NIMR transitioned to The Francis Crick Institute in April 2015, my ‘scientific GPS coordinates’ were slightly adjusted to focus on human disease. The opportunity to move my lab to Genentech in May 2016 satisfied every aspect of my new coordinates: world-class scientists using cutting-edge approaches to tackle the most important scientific questions, with the aim of improving human health.
Postdoctoral Mentor
The postdoctoral program at Genentech combines the best of many worlds. Surrounded by state-of-the-art intellectual and infrastructural resources, postdoctoral researchers at Genentech can tackle the biggest and most important unanswered questions in science. Genentech offers both a nurturing and scientifically challenging environment where postdocs can sharpen their skills in a highly collaborative environment, laying down the foundations for a future in science.
Featured Publication
Type 2 immunity in tissue repair and fibrosis.
Nat Rev Immunol. 2018 2018 Jan;18(1):62-76
Gieseck RL 3rd, Wilson MS, Wynn TA.
Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens.
Science. 2019 Nov 1;366(6465):599-606.
Mina MJ, Kula T, Leng Y, Li M, de Vries RD, Knip M, Siljander H, Rewers M, Choy DF, Wilson MS, Larman HB, Nelson AN, Griffin DE, de Swart RL, Elledge SJ.
ncRNAs in Type-2 Immunity.
Noncoding RNA. 2020 Mar 6;6(1):10.
Guidi R, Wedeles CJ, Wilson MS.
We investigate the cellular and molecular pathways that contribute to inflammatory diseases. Focusing on mucosal immunity, we use a variety of in-vivo, in-vitro and in-silico approaches to ask fundamental questions. Currently, we are asking:
- What are the genetic determinants of inflammatory diseases? How do they influence inflammatory pathways and can we manipulate them to curb inflammation and disease progression?
- Can transcriptional data sets be analyzed in more creative ways to identify gene networks and pathways that contribute to disease?
- How do local changes in tissue architecture affect immunological principles?
- What role do regulatory RNAs play in inflammatory pathways?
- University of Edinburgh, Ph. D – 2004
- Kings College London, B. Sc. – 2000
- European Research Council Consolidator Award – 2015
- MRC Centenary award – 2012
- Medical Research Council (MRC) Tenure Track – 2010
- Lady TATA Memorial Trust Award – 2010
- Wellcome Trust Prize PhD Studentship – 2001
- Wellcome Trust Summer Studentship – 1999
- Fellows Award for Research Excellence (FARE). NIH – '07,'09,'10