"Only with scientific rigor, a creative mind and immense dedication can we drive innovation and come up with new and better treatments."
I joined Genentech as a postdoctoral fellow in 1997 and in 1999 as a scientist in the Immunology Department. I was extremely motivated to join Genentech since it is one of the few places where high quality discovery research and drug development are directly connected.
What makes Genentech so special is the strong emphasis on science. In the process of discovering new immune-pathways and developing potential new therapies based on these discoveries, I learned to appreciate the many aspects that are unique to Genentech culture, including the collaborative and creative spirit among the scientists. I'm proud of being a part of this culture.
The collaborative and creative spirit at Genentech creates an ideal environment for post-docs to live their dream of making game-changing scientific discoveries. Genentech provides the opportunity to pursue important scientific questions in an environment rich in resources. Mentoring post-docs and preparing them for a future as independent investigators has been extremely gratifying.
Nature. 2014 Feb 27;506(7489):456-62.
My lab is dedicated to two main areas of biology. First, we are exploring various immune-related pathways in pursuit of new therapeutics for Age-related Macular Degeneration (AMD) and diabetic retinopathy, major blinding diseases caused by neovascularization, inflammation and neuronal degeneration. Second, we are identifying and validating new targets to treat chronic inflammatory and autoimmune diseases. In both research areas, we are using the power of human genetics to better understand which pathways are important drivers or modulators of the human disease.