"Cells are talking; we need the right ears to listen."
Throughout my career, I have been fascinated by the complexity of information conveyed by seemingly simple protein interactions. At Genentech, my lab focuses on discovering the receptor-ligand interactions that underlie human disease by combining an engineer’s eye for technological innovation with a drive to answer scientific questions. Here, I collaborate closely with Genentech’s leading experts in immunology, oncology, neuroscience and infectious diseases to fuel therapeutic discoveries with strong foundations in basic science.
Mol. Biol. Cell. mbc.E17-10-0596. * indicates co-first authorship.
PNAS. 108(39). Pp. 16271-6.
The experimental obstinance of receptor proteins creates opportunities for new strategies to reveal undiscovered cellular crosstalk that is uniquely accessible to large-molecule interventions. My lab develops and implements proteomic and cell-based technologies specifically designed to map receptor-ligand interaction networks.