/ Medical Professionals


Rigorous and groundbreaking science has always been at the core of what we do at Genentech. Our R&D activities are focused on applying excellent science to discover and develop potential new medicines with the goal of becoming first-in-class or best-in-class therapeutics.

  • Oncology
  • Immunology
  • Neuroscience
  • Metabolism
  • Infectious Disease
  • Ophthalmology
Managed by Roche
Molecule Indication Phase
Alectinib ALK+ metastatic non-small cell lung cancer *
Anti-CD20/CD3 MAb Hematologic malignancies
Anti-OX40 MAb Solid tumors
Anti-TIGIT MAb Solid tumors
Antibody drug conjugate Pancreatic and ovarian cancers
Antibody drug conjugate Non-Hodgkin's lymphoma
Atezolizumab Solid tumors *
Metastatic melanoma *

1st line glioblastoma multiforme


1st line metastatic ovarian cancer


Adjuvant breast cancer, HER2-negative


Adjuvant breast cancer, HER2-positive


Adjuvant non-small cell lung cancer


High-risk carcinoid

ChK1 Inhibitor (GDC-0575)

Solid tumors

Cobimetinib Solid tumors *
Metastatic melanoma *

1st line metastatic non-small cell lung cancer, EGFR mutation positive

IDO Inhibitor (GDC-0919) Solid tumors
Ipatasertib Solid tumors *
Gastric cancer *
Triple negative breast cancer *
Prostate cancer *

Diffuse large B-cell lymphoma


Front-line indolent non-Hodgkin's lymphoma


Refractory indolent Non Hodgkin's lymphoma


Front-line chronic lymphocytic leukemia


Early HER2-positive breast cancer


HER2-positive gastric cancer


2nd line HER2-positive metastatic breast cancer

PI3K Inhibitor (GDC-0077) Solid tumors and ER+ HER2-negative breast cancer
Polatuzumab vedotin Non-Hodgkin's lymphoma and diffuse large B-cell lymphoma *
SERD (GDC-0810) ER+ HER2-negative breast cancer
SERD (GDC-0927) ER+ HER2-negative breast cancer
Taselisib HER2-negative metastatic breast cancer *
Solid tumors and HR+ breast cancer *
Trastuzumab emtansine

1st line HER2-positive metastatic breast cancer


3rd line HER2-positive metastatic breast cancer


Adjuvant metastatic melanoma, BRAF mutation positive


Papillary thyroid cancer, BRAF mutation positive


Metastatic melanoma, BRAF mutation positive


Chronic lymphocytic leukemia and non-Hodgkin's lymphoma


Operable basal cell carcinoma

Anti-ST2 MAb Asthma
BTK Inhibitor (GDC-0853) Rheumatoid arthritis and lupus
Etrolizumab Ulcerative colitis *
GDC-3280 Interstitial lung disease
IL22-Fc Inflammatory diseases

Severe asthma

New Molecular Entity Asthma
Obinutuzumab Lupus Nephritis
Rituximab Pemphigus Vulgaris
Sodium Hyaluronate


Tocilizumab Early rheumatoid arthritis *
Systemic sclerosis *
Giant Cell Arteritis *
Anti-Tau Alzheimer’s Disease
Crenezumab Alzheimer's Disease *
Gantenerumab Alzheimer's Disease *
GDC-0134 Amyotrophic lateral sclerosis
Nav1.7 Inhibitor (GDC-0310) Pain

Primary progressive multiple sclerosis


Relapsing multiple sclerosis

Anti-FGFR1/KLB MAb Type 2 diabetes
Anti-Influenza A MAb Severe influenza
Anti-S. aureus TAC Staphylococcus aureus
Lampalizumab Geographic atrophy associated with advanced age-related macular degeneration *

Sustained delivery age-related macular degeneration

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Partner with Us

Approximately 50% of our pipeline and marketed products involve some kind of collaboration.