Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

950 results

Science, 2016, ISSN: 0036-8075
Yadav, Mahesh; Delamarre, Lélia
Analytical chemistry, 2016, ISSN: 0003-2700
Hosken, Brian D; Li, Charlene; Mullappally, Berny; Co, Carl; Zhang, Boyan
Drug Metabolism and Disposition, 2016,
Almond, Lisa M.; Mukadam, Sophie; Gardner, Iain; Okialda, Krystle; Wong, Susan; Hatley, Oliver; Tay, Suzanne; Rowland-Yeo, Karen; Jamei, Masoud; Rostami-Hodjegan, Amin; Kenny, Jane R.
Nature, 2016, ISSN: 0028-0836
Vande Walle, Lieselotte; Jiménez Fernández, Daniel; Demon, Dieter; Van Laethem, Naomi; Van Hauwermeiren, Filip; Van Gorp, Hanne; Van Opdenbosch, Nina; Kayagaki, Nobuhiko; Lamkanfi, Mohamed
Nature chemical biology, 2016, ISSN: 1552-4450
Vinogradova, Maia; Gehling, Victor S; Gustafson, Amy; Arora, Shilpi; Tindell, Charles A; Wilson, Catherine; Williamson, Kaylyn E; Guler, Gulfem D; Gangurde, Pranoti; Manieri, Wanda; Busby, Jennifer; Flynn, E Megan; Lan, Fei; Kim, Hyo-Jin; Odate, Shobu; Cochran, Andrea G; Liu, Yichin; Wongchenko, Matthew; Yang, Yibin; Cheung, Tommy K; Maile, Tobias M; Lau, Ted; Costa, Michael; Hegde, Ganapati V; Jackson, Erica; Pitti, Robert; Arnott, David; Bailey, Christopher; Bellon, Steve; Cummings, Richard T; Albrecht, Brian K; Harmange, Jean-Christophe; Kiefer, James R; Trojer, Patrick; Classon, Marie
PloS one, 2016, ISSN: 1932-6203
Goldstein, Leonard D; Cao, Yi; Pau, Gregoire; Lawrence, Michael; Wu, Thomas D; Seshagiri, Somasekar; Gentleman, Robert
Nature, 2016, ISSN: 0028-0836
Haverty, Peter M; Lin, Eva; Tan, Jenille; Yu, Yihong; Lam, Billy; Lianoglou, Steve; Neve, Richard M; Martin, Scott; Settleman, Jeff; Yauch, Robert L; Bourgon, Richard
Blood, 2016, ISSN: 0006-4971
Le Gall, Sylvain M; Szabo, Roman; Lee, Melody; Kirchhofer, Daniel; Craik, Charles S; Bugge, Thomas H; Camerer, Eric
Analytical biochemistry, 2016, ISSN: 0003-2697
Valisheva, Ildana; Harris, Reed J; Zhu-Shimoni, Judith
Chemical research in toxicology, 2016, ISSN: 0893-228X
Dambach, Donna M; Misner, Dinah; Brock, Mathew; Fullerton, Aaron; Proctor, William; Maher, Jonathan; Lee, Dong; Ford, Kevin; Diaz, Dolores
Developmental cell, 2016, ISSN: 1534-5807
Ye, Weilan
Science Translational Medicine, 2016, ISSN: 1946-6234
Romero, Pedro; Banchereau, Jacques; Bhardwaj, Nina; Cockett, Mark; Disis, Mary L; Dranoff, Glenn; Gilboa, Eli; Hammond, Scott A; Hershberg, Robert; Korman, Alan J; Kvistborg, Pia; Melief, Cornelis; Mellman, Ira; Palucka, A Karolina; Redchenko, Irina; Robins, Harlan; Sallusto, Federica; Schenkelberg, Theodore; Schoenberger, Stephen; Sosman, Jeffrey; Türeci, Özlem; Van den Eynde, Benoît; Koff, Wayne; Coukos, George
Cancer cell, 2016, ISSN: 1535-6108
Pusapati, Raju V; Daemen, Anneleen; Wilson, Catherine; Sandoval, Wendy; Gao, Min; Haley, Benjamin; Baudy, Andreas R; Hatzivassiliou, Georgia; Evangelista, Marie; Settleman, Jeff
Current opinion in immunology, 2016, ISSN: 0952-7915
Brezski, Randall J; Georgiou, George
Journal of clinical oncology, 2016, ISSN: 0732-183X
Schmid, Peter; Pinder, Sarah E; Wheatley, Duncan; Macaskill, Jane; Zammit, Charles; Hu, Jennifer; Price, Robert; Bundred, Nigel; Hadad, Sirwan; Shia, Alice; Sarker, Shah-Jalal; Lim, Louise; Gazinska, Patrycja; Woodman, Natalie; Korbie, Darren; Trau, Matt; Mainwaring, Paul; Gendreau, Steven; Lackner, Mark R; Derynck, Mika; Wilson, Timothy R; Butler, Hannah; Earl, Gemma; Parker, Peter; Purushotham, Arnie; Thompson, Alastair
Immunity, 2016, ISSN: 1074-7613
Ebert, Peter J R; Cheung, Jeanne; Yang, Yagai; McNamara, Erin; Hong, Rebecca; Moskalenko, Marina; Gould, Stephen E; Maecker, Heather; Irving, Bryan A; Kim, Jeong M; Belvin, Marcia; Mellman, Ira
Cancer cell, 2016, ISSN: 1535-6108
Foster, Scott A; Whalen, Daniel M; Özen, Ayşegül; Wongchenko, Matthew J; Yin, JianPing; Yen, Ivana; Schaefer, Gabriele; Mayfield, John D; Chmielecki, Juliann; Stephens, Philip J; Albacker, Lee A; Yan, Yibing; Song, Kyung; Hatzivassiliou, Georgia; Eigenbrot, Charles; Yu, Christine; Shaw, Andrey S; Manning, Gerard; Skelton, Nicholas J; Hymowitz, Sarah G; Malek, Shiva
Nature biotechnology, 2016, ISSN: 1087-0156
Budzinski, Kristi L; Koenig, Stefan G; O'Connor, Deborah A; Wu, Tse-Sung
Nature biotechnology, 2016, ISSN: 1087-0156
Amit, Ido; Baker, David; Barker, Roger; Berger, Bonnie; Bertozzi, Carolyn; Bhatia, Sangeeta; Biffi, Alessandra; Demichelis, Francesca; Doudna, Jennifer; Dowdy, Steven F; Endy, Drew; Helmstaedter, Moritz; Junca, Howard; June, Carl; Kamb, Sasha; Khvorova, Anastasia; Kim, Dae-Hyeong; Kim, Jin-Soo; Krishnan, Yamuna; Lakadamyali, Melike; Lappalainen, Tuuli; Lewin, Sharon; Liao, James; Loman, Nick; Lundberg, Emma; Lynd, Lee; Martin, Cathie; Mellman, Ira; Miyawaki, Atsushi; Mummery, Christine; Nelson, Karen; Paz, Jeanne; Peralta-Yahya, Pamela; Picotti, Paola; Polyak, Kornelia; Prather, Kristala; Qin, Jun; Quake, Stephen; Regev, Aviv; Rogers, John A; Shetty, Reshma; Sommer, Morten; Stevens, Molly; Stolovitzky, Gustavo; Takahashi, Masayo; Tang, Fuchou; Teichmann, Sarah; Torres-Padilla, Maria-Elena; Tripathi, Leena; Vemula, Praveen; Verdine, Greg; Vollmer, Frank; Wang, Jun; Ying, Jackie Y; Zhang, Feng; Zhang, Tian
Nature genetics, 2016, ISSN: 1061-4036
Bonilla, Ximena; Parmentier, Laurent; King, Bryan; Bezrukov, Fedor; Kaya, Gürkan; Zoete, Vincent; Seplyarskiy, Vladimir B; Sharpe, Hayley J; McKee, Thomas; Letourneau, Audrey; Ribaux, Pascale G; Popadin, Konstantin; Basset-Seguin, Nicole; Chaabene, Rouaa Ben; Santoni, Federico A; Andrianova, Maria A; Guipponi, Michel; Garieri, Marco; Verdan, Carole; Grosdemange, Kerstin; Sumara, Olga; Eilers, Martin; Aifantis, Iannis; Michielin, Olivier; de Sauvage, Frederic J; Antonarakis, Stylianos E; Nikolaev, Sergey I
Journal of clinical oncology, 2016, ISSN: 0732-183X
Powles, Thomas; Lackner, Mark R; Oudard, Stéphane; Escudier, Bernard; Ralph, Christy; Brown, Janet E; Hawkins, Robert E; Castellano, Daniel; Rini, Brian I; Staehler, Michael D; Ravaud, Alain; Lin, Wei; O'Keeffe, Bridget; Wang, Yulei; Lu, Shan; Spoerke, Jill M; Huw, Ling-Yuh; Byrtek, Michelle; Zhu, Rui; Ware, Joseph A; Motzer, Robert J
Nature genetics, 2016, ISSN: 1061-4036
Bueno, Raphael; Stawiski, Eric W; Goldstein, Leonard D; Durinck, Steffen; De Rienzo, Assunta; Modrusan, Zora; Gnad, Florian; Nguyen, Thong T; Jaiswal, Bijay S; Chirieac, Lucian R; Sciaranghella, Daniele; Dao, Nhien; Gustafson, Corinne E; Munir, Kiara J; Hackney, Jason A; Chaudhuri, Amitabha; Gupta, Ravi; Guillory, Joseph; Toy, Karen; Ha, Connie; Chen, Ying-Jiun; Stinson, Jeremy; Chaudhuri, Subhra; Zhang, Na; Wu, Thomas D; Sugarbaker, David J; de Sauvage, Frederic J; Richards, William G; Seshagiri, Somasekar
Pharmaceutical Research, 2016, ISSN: 0724-8741
Mao, Jialin; Tay, Suzanne; Khojasteh, Cyrus S; Chen, Yuan; Hop, Cornelis E C A; Kenny, Jane R
Neuron, 2016, ISSN: 0896-6273
Hackos, David H; Lupardus, Patrick J; Grand, Teddy; Chen, Yelin; Wang, Tzu-Ming; Reynen, Paul; Gustafson, Amy; Wallweber, Heidi J A; Volgraf, Matthew; Sellers, Benjamin D; Schwarz, Jacob B; Paoletti, Pierre; Sheng, Morgan; Zhou, Qiang; Hanson, Jesse E
Cell stem cell, 2016,
Tetteh, Paul W; Basak, Onur; Farin, Henner F; Wiebrands, Kay; Kretzschmar, Kai; Begthel, Harry; van den Born, Maaike; Korving, Jeroen; de Sauvage, Frederic; van Es, Johan H; van Oudenaarden, Alexander; Clevers, Hans
Nature chemical biology, 2016, ISSN: 1552-4450
Nile, Aaron H; Hannoush, Rami N
Cell, 2016, ISSN: 0092-8674
Yang, Chiao-Wen; Hojer, Caroline D; Zhou, Meijuan; Wu, Xiumin; Wuster, Arthur; Lee, Wyne P; Yaspan, Brian L; Chan, Andrew C
PloS one, 2016, ISSN: 1932-6203
Wedemeyer, Heiner; Forns, Xavier; Hézode, Christophe; Lee, Samuel S; Scalori, Astrid; Voulgari, Athina; Le Pogam, Sophie; Nájera, Isabel; Thommes, James A
Nature, 2016, ISSN: 0028-0836
Storm, Elaine E; Durinck, Steffen; de Sousa e Melo, Felipe; Tremayne, Jarrod; Kljavin, Noelyn; Tan, Christine; Ye, Xiaofen; Chiu, Cecilia; Pham, Thinh; Hongo, Jo-Anne; Bainbridge, Travis; Firestein, Ron; Blackwood, Elizabeth; Metcalfe, Ciara; Stawiski, Eric W; Yauch, Robert L; Wu, Yan; de Sauvage, Frederic J
Journal of experimental medicine, 2015, ISSN: 0022-1007
Heaton, Steven M; Borg, Natalie A; Dixit, Vishva M
PloS one, 2015, ISSN: 1932-6203
Sriram, N; Mills, Jennifer; Lang, Edward; Dickson, Holli K; Hamann, Heidi A; Nosek, Brian A; Schiller, Joan H
Science, 2015, ISSN: 0036-8075
Ahuja, Shivani; Mukund, Susmith; Deng, Lunbin; Khakh, Kuldip; Chang, Elaine; Ho, Hoangdung; Shriver, Stephanie; Young, Clint; Lin, Sophia; Johnson, J P, Jr; Wu, Ping; Li, Jun; Coons, Mary; Tam, Christine; Brillantes, Bobby; Sampang, Honorio; Mortara, Kyle; Bowman, Krista K; Clark, Kevin R; Estevez, Alberto; Xie, Zhiwei; Verschoof, Henry; Grimwood, Michael; Dehnhardt, Christoph; Andrez, Jean-Christophe; Focken, Thilo; Sutherlin, Daniel P; Safina, Brian S; Starovasnik, Melissa A; Ortwine, Daniel F; Franke, Yvonne; Cohen, Charles J; Hackos, David H; Koth, Christopher M; Payandeh, Jian
Nature, 2015, ISSN: 0028-0836
Wertz, Ingrid E; Newton, Kim; Seshasayee, Dhaya; Kusam, Saritha; Lam, Cynthia; Zhang, Juan; Popovych, Nataliya; Helgason, Elizabeth; Schoeffler, Allyn; Jeet, Surinder; Ramamoorthi, Nandhini; Kategaya, Lorna; Newman, Robert J; Horikawa, Keisuke; Dugger, Debra; Sandoval, Wendy; Mukund, Susmith; Zindal, Anuradha; Martin, Flavius; Quan, Clifford; Tom, Jeffrey; Fairbrother, Wayne J; Townsend, Michael; Warming, Søren; DeVoss, Jason; Liu, Jinfeng; Dueber, Erin; Caplazi, Patrick; Lee, Wyne P; Goodnow, Christopher C; Balazs, Mercedesz; Yu, Kebing; Kolumam, Ganesh; Dixit, Vishva M
Immunity, 2015, ISSN: 1074-7613
Pikor, Natalia B; Astarita, Jillian L; Summers-Deluca, Leslie; Galicia, Georgina; Qu, Joy; Ward, Lesley A; Armstrong, Susan; Dominguez, Claudia X; Malhotra, Deepali; Heiden, Brendan; Kay, Robert; Castanov, Valera; Touil, Hanane; Boon, Louis; O'Connor, Paul; Bar-Or, Amit; Prat, Alexandre; Ramaglia, Valeria; Ludwin, Samuel; Turley, Shannon J; Gommerman, Jennifer L
Neuron, 2015,
Y. Joy Yu Zuchero; Xiaocheng Chen; Nga Bien-Ly; Daniela Bumbaca; Raymond K. Tong; Xiaoying Gao; Shuo Zhang; Kwame Hoyte; Wilman Luk; Melanie A. Huntley; Lilian Phu; Christine Tan; Dara Kallop; Robby M. Weimer; Yanmei Lu; Donald S. Kirkpatrick; James A. Ernst; Ben Chih; Mark S. Dennis; Ryan J. Watts
Nature genetics, 2015, ISSN: 1061-4036
Zhou, Qing; Wang, Hongying; Schwartz, Daniella M; Stoffels, Monique; Park, Yong Hwan; Zhang, Yuan; Yang, Dan; Demirkaya, Erkan; Takeuchi, Masaki; Tsai, Wanxia Li; Layons, Jonathan J; Yu, Xiaomin; Ouyang, Claudia; Chen, Celeste; Chin, David T; Zaal, Kristien; Chandrasekharappa, Settara C; P Hanson, Eric; Yu, Zhen; Mullikin, James C; Hasni, Sarfaraz A; Wertz, Ingrid E; Ombrello, Amanda K; Stone, Deborah L; Hoffmann, Patrycja; Jones, Anne; Barham, Beverly K; Leavis, Helen L; van Royen-Kerkof, Annet; Sibley, Cailin; Batu, Ezgi D; Gül, Ahmet; Siegel, Richard M; Boehm, Manfred; Milner, Joshua D; Ozen, Seza; Gadina, Massimo; Chae, JaeJin; Laxer, Ronald M; Kastner, Daniel L; Aksentijevich, Ivona
Cell, 2015, ISSN: 0092-8674
Suriben, Rowena; Kaihara, Kelly A.; Paolino, Magdalena; Reichelt, Mike; Kummerfeld, Sarah K.; Modrusan, Zora; Dugger, Debra L.; Newton, Kim; Sagolla, Meredith; Webster, Joshua; Liu , Jinfeng; Hebrok, Matthias; Dixit, Vishva M.
Primary results of the health-related quality of life assessment from the phase III gadolin study of obinutuzumab plus bendamustine compared with bendamustine alone in patients with rituximab-refractory, indolent non-hodgkin lymphoma
Blood, 2015, ISSN: 0006-4971
Cheson, Bruce D.; Trask, Peter C.; Gribben, John; Dimier, Natalie; Kimby, Eva; Lugtenburg, Pieternella J.; Thieblemont, Catherine; Fritsch, Elisabeth Wassner; Sehn, Laurie H.; Cheson, B.D.
Science signaling, 2015,
Sun, Yonglian; Peng, Ivan; Webster, Joshua D; Suto, Eric; Lesch, Justin; Wu, Xiumin; Senger, Kate; Francis, George; Barrett, Kathy; Collier, Jenna L; Burch, Jason D; Zhou, Meijuan; Chen, Yuan; Chan, Connie; Eastham-Anderson, Jeff; Ngu, Hai; Li, Olga; Staton, Tracy; Havnar, Charles; Jaochico, Allan; Jackman, Janet; Jeet, Surinder; Riol-Blanco, Lorena; Wu, Lawren C; Choy, David F; Arron, Joseph R; McKenzie, Brent S; Ghilardi, Nico; Ismaili, Moulay Hicham Alaoui; Pei, Zhonghua; DeVoss, Jason; Austin, Cary D; Lee, Wyne P; Zarrin, Ali A
Journal of Clinical Investigation, 2015,
Hitchcock, Jessica R.; Cook, Charlotte N.; Bobat, Saeeda; Ross, Ewan A.; Flores-Langarica, Adriana; Lowe, Kate L.; Khan, Mahmood; Coral Dominguez-Medina, C.; Lax, Sian; Carvalho-Gaspar, Manuela; Hubscher, Stefan; Ed Rainger, G.; Cobbold, Mark; Buckley, Christopher D.; Mitchell, Tim J.; Mitchell, Andrea; Jones, Nick D.; Van Rooijen, N.; Kirchhofer, Daniel; Henderson, Ian R.; Adams, David H.; Watson, Steve P.; Cunningham, Adam F.
Science, 2015,
Alexander Jaworski; Irene Tom; Raymond K. Tong; Holly K. Gildea; Alexander W. Koch; Lino C. Gonzalez; Marc Tessier-Lavigne
Nature, 2015, ISSN: 0028-0836
Lafkas, Daniel; Shelton, Amy; Chiu, Cecilia; de Leon Boenig, Gladys; Chen, Yongmei; Stawicki, Scott S; Siltanen, Christian; Reichelt, Mike; Zhou, Meijuan; Wu, Xiumin; Eastham-Anderson, Jeffrey; Moore, Heather; Roose-Girma, Meron; Chinn, Yvonne; Hang, Julie Q; Warming, Søren; Egen, Jackson; Lee, Wyne P; Austin, Cary; Wu, Yan; Payandeh, Jian; Lowe, John B; Siebel, Christian W
Science translational medicine, 2015, ISSN: 1946-6234
Junttila, Melissa R; Mao, Weiguang; Wang, Xi; Wang, Bu-Er; Pham, Thinh; Flygare, John; Yu, Shang-Fan; Yee, Sharon; Goldenberg, David; Fields, Carter; Eastham-Anderson, Jeffrey; Singh, Mallika; Vij, Rajesh; Hongo, Jo-Anne; Firestein, Ron; Schutten, Melissa; Flagella, Kelly; Polakis, Paul; Polson, Andrew G
PloS one, 2015, ISSN: 1932-6203
Hsu, Jessie J; Finkelstein, Dianne M; Schoenfeld, David A
Cell stem cell, 2015,
Metcalfe, Ciara; Siebel, Christian W
Nature, 2015, ISSN: 0028-0836
Lehar, Sophie M; Pillow, Thomas; Xu, Min; Staben, Leanna; Kajihara, Kimberly K; Vandlen, Richard; DePalatis, Laura; Raab, Helga; Hazenbos, Wouter L; Hiroshi Morisaki, J; Kim, Janice; Park, Summer; Darwish, Martine; Lee, Byoung-Chul; Hernandez, Hilda; Loyet, Kelly M; Lupardus, Patrick; Fong, Rina; Yan, Donghong; Chalouni, Cecile; Luis, Elizabeth; Khalfin, Yana; Plise, Emile; Cheong, Jonathan; Lyssikatos, Joseph P; Strandh, Magnus; Koefoed, Klaus; Andersen, Peter S; Flygare, John A; Wah Tan, Man; Brown, Eric J; Mariathasan, Sanjeev
Nature Genetics, 2015, ISSN: 1061-4036
Bentham, James; Morris, David L; Cunninghame Graham, Deborah S; Pinder, Christopher L; Tombleson, Philip; Behrens, Timothy W; Martín, Javier; Fairfax, Benjamin P; Knight, Julian C; Chen, Lingyan; Replogle, Joseph; Syvänen, Ann-Christine; Rönnblom, Lars; Graham, Robert R; Wither, Joan E; Rioux, John D; Alarcón-Riquelme, Marta E; Vyse, Timothy J
Neuron, 2015, ISSN: 0896-6273
Bien-Ly, Nga; Boswell, C Andrew; Jeet, Surinder; Beach, Thomas G; Hoyte, Kwame; Luk, Wilman; Shihadeh, Vera; Ulufatu, Sheila; Foreman, Oded; Lu, Yanmei; DeVoss, Jason; van der Brug, Marcel; Watts, Ryan J
Analytical chemistry, 2015, ISSN: 0003-2700
Macchi, Frank D; Yang, Feng; Li, Charlene; Wang, Chenchen; Dang, Anh Nguyen; Marhoul, Joseph C; Zhang, Hui-Min; Tully, Timothy; Liu, Hongbin; Yu, X Christopher; Michels, David A
Blood, 2015, ISSN: 0006-4971
Byrd, John C; Flynn, Joseph; Kipps, Thomas J; Boxer, Michael; Kolibaba, Kathryn S; Carlile, David J; Fingerle-Rowson, Guenter; Tyson, Nicola; Hirata, Jamie; Sharman, Jeff P
PloS one, 2015, ISSN: 1932-6203
Morley, Roland; Cardenas, Alison; Hawkins, Peter; Suzuki, Yasuyo; Paton, Virginia; Phan, See-Chun; Merchant, Mark; Hsu, Jessie; Yu, Wei; Xia, Qi; Koralek, Daniel; Luhn, Patricia; Aldairy, Wassim
Journal of clinical pharmacology, 2015, ISSN: 0091-2700
Wei, Xiaohui; Kenny, Jane R; Dickmann, Leslie; Maciuca, Romeo; Looney, Carrie; Tang, Meina T
PloS one, 2015, ISSN: 1932-6203
Coady, Alison; Xu, Min; Phung, Qui; Cheung, Tommy K; Bakalarski, Corey; Alexander, Mary Kate; Lehar, Sophie M; Kim, Janice; Park, Summer; Tan, Man-Wah; Nishiyama, Mireille
Science, 2015, ISSN: 0036-8075
Hung, T; Pratt, G; Sundararaman, B; Townsend, M J; Chaivorapol, C; Bhangale, T; Graham, R R; Ortmann, W; Criswell, L A; Yeo, G; Behrens, T W
Nature, 2015,
Nobuhiko Kayagaki; Irma B. Stowe; Bettina L. Lee; Karen O’Rourke; Keith Anderson; Soren Warming; Trinna Cuellar; Benjamin Haley; Merone Roose-Girma; Qui T. Phung; Peter S. Liu; Jennie R. Lill; Hong Li; Jiansheng Wu; Sarah Kummerfeld; Juan Zhang; Wyne P. Lee; Scott J. Snipas; Guy S. Salvesen; Lucy X. Morris; Linda Fitzgerald; Yafei Zhang; Edward M. Bertram; Christopher C. Goodnow; Vishva M. Dixit
Science translational medicine, 2015, ISSN: 1946-6234
van der Brug, Marcel P; Singleton, Andrew; Gasser, Thomas; Lewis, Patrick A
British journal of clinical pharmacology, 2015, ISSN: 0306-5251
Han, Kelong; Peyret, Thomas; Quartino, Angelica; Gosselin, Nathalie H; Gururangan, Sridharan; Daw, Najat C; Navid, Fariba; Jin, Jin; Allison, David E
Science translational medicine, 2015, ISSN: 1946-6234
Choy, David F; Hart, Kevin M; Borthwick, Lee A; Shikotra, Aarti; Nagarkar, Deepti R; Siddiqui, Salman; Jia, Guiquan; Ohri, Chandra M; Doran, Emma; Vannella, Kevin M; Butler, Claire A; Hargadon, Beverley; Sciurba, Joshua C; Gieseck, Richard L; Thompson, Robert W; White, Sandra; Abbas, Alexander R; Jackman, Janet; Wu, Lawren C; Egen, Jackson G; Heaney, Liam G; Ramalingam, Thirumalai R; Arron, Joseph R; Wynn, Thomas A; Bradding, Peter
Journal of Biological Chemistry, 2015, ISSN: 0021-9258
Comps-Agrar, Laëtitia; Dunshee, Diana Ronai; Eaton, Dan L; Sonoda, Junichiro
PloS one, 2015, ISSN: 1932-6203
Kasperkiewicz, Paulina; Poreba, Marcin; Snipas, Scott J; Lin, S Jack; Kirchhofer, Daniel; Salvesen, Guy S; Drag, Marcin
Journal of clinical oncology, 2015, ISSN: 0732-183X
Casulo, Carla; Byrtek, Michelle; Dawson, Keith L; Zhou, Xiaolei; Farber, Charles M; Flowers, Christopher R; Hainsworth, John D; Maurer, Matthew J; Cerhan, James R; Link, Brian K; Zelenetz, Andrew D; Friedberg, Jonathan W
Journal of clinical oncology, 2015, ISSN: 0732-183X
Sandmann, Thomas; Bourgon, Richard; Garcia, Josep; Li, Congfen; Cloughesy, Timothy; Chinot, Olivier L; Wick, Wolfgang; Nishikawa, Ryo; Mason, Warren; Henriksson, Roger; Saran, Frank; Lai, Albert; Moore, Nicola; Kharbanda, Samir; Peale, Franklin; Hegde, Priti; Abrey, Lauren E; Phillips, Heidi S; Bais, Carlos
Blood, 2015, ISSN: 0006-4971
Wagner-Johnston, Nina D; Link, Brian K; Byrtek, Michelle; Dawson, Keith L; Hainsworth, John; Flowers, Christopher R; Friedberg, Jonathan W; Bartlett, Nancy L
PloS one, 2015, ISSN: 1932-6203
D'Osualdo, Andrea; Anania, Veronica G; Yu, Kebing; Lill, Jennie R; Kaufman, Randal J; Matsuzawa, Shu-Ichi; Reed, John C
Journal of biological chemistry, 2015, ISSN: 0021-9258
Koenig, Patrick; Lee, Chingwei V; Sanowar, Sarah; Wu, Ping; Stinson, Jeremy; Harris, Seth F; Fuh, Germaine
Science signaling, 2015,
Fasci, Domenico; Anania, Veronica G; Lill, Jennie R; Salvesen, Guy S
Current opinion in chemical biology, 2015, ISSN: 1367-5931
Hannoush, Rami N
British journal of clinical pharmacology, 2015, ISSN: 0306-5251
Pillai, Venkateswaran C; Han, Kelong; Beigi, Richard H; Hankins, Gary D; Clark, Shannon; Hebert, Mary F; Easterling, Thomas R; Zajicek, Anne; Ren, Zhaoxia; Caritis, Steve N; Venkataramanan, Raman
Current opinion in pharmacology, 2015, ISSN: 1471-4892
E Templeton, Ian; Musib, Luna
Journal of Medicinal Chemistry, 2015,
Crawford, James J.; Lee, Wendy; Aliagas, Ignacio; Mathieu, Simon; Hoeflich, Klaus P.; Zhou, Wei; Wang, Weiru; Rouge, Lionel; Murray, Lesley; La, Hank; Liu, Ning; Fan, Peter W.; Cheong, Jonathan; Heise, Christopher E.; Ramaswamy, Sreemathy; Mintzer, Robert; Liu, Yanzhou; Chao, Qi; Rudolph, Joachim
Nature methods, 2015, ISSN: 1548-7091
Freedman, Leonard P; Gibson, Mark C; Ethier, Stephen P; Soule, Howard R; Neve, Richard M; Reid, Yvonne A
Journal of clinical pharmacology, 2015, ISSN: 0091-2700
Liu, Lichuan; Bello, Akintunde; Dresser, Mark J; Heald, Donald; Komjathy, Steven Ferenc; O'Mara, Edward; Rogge, Mark; Stoch, S Aubrey; Robertson, Sarah M
Toxicological sciences, 2015, ISSN: 1096-0929
Kaplan, Barbara L F; Li, Jinze; LaPres, John J; Pruett, Stephen B; Karmaus, Peer W F
Journal of clinical pharmacology, 2015, ISSN: 0091-2700
Rogge, Mark C; Dresser, Mark; Fossler, Michael; Heald, Donald; Stoch, S Aubrey; Vanevski, Konstantina M; Bello, Akintunde
Science, 2015, ISSN: 0036-8075
Delamarre, Lélia; Mellman, Ira; Yadav, Mahesh
Science, 2015, ISSN: 0036-8075
Delamarre, Lelia; Mellman, Ira; Yadav, Mahesh
Science translational medicine, 2015, ISSN: 1946-6234
Sun, Liping L; Ellerman, Diego; Mathieu, Mary; Hristopoulos, Maria; Chen, Xiaocheng; Li, Yijin; Yan, Xiaojie; Clark, Robyn; Reyes, Arthur; Stefanich, Eric; Mai, Elaine; Young, Judy; Johnson, Clarissa; Huseni, Mahrukh; Wang, Xinhua; Chen, Yvonne; Wang, Peiyin; Wang, Hong; Dybdal, Noel; Chu, Yu-Waye; Chiorazzi, Nicholas; Scheer, Justin M; Junttila, Teemu; Totpal, Klara; Dennis, Mark S; Ebens, Allen J
Nature medicine, 2015, ISSN: 1078-8956
Gould, Stephen E; Junttila, Melissa R; de Sauvage, Frederic J
Pharmaceutical research, 2015, ISSN: 0724-8741
Heljo, P; Ross, A; Zarraga, I E; Pappenberger, A; Mahler, H-C
Nature, 2015, ISSN: 0028-0836
Yu, Mamie; Selvaraj, Suresh K; Liang-Chu, May M Y; Aghajani, Sahar; Busse, Matthew; Yuan, Jean; Lee, Genee; Peale, Franklin; Klijn, Christiaan; Bourgon, Richard; Kaminker, Joshua S; Neve, Richard M
PloS one, 2015, ISSN: 1932-6203
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Journal of Experimental Medicine, 2013, ISSN: 0022-1007
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Current Opinion in Chemical Biology, 2013, ISSN: 1367-5931
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EMBO Journal, 2013, ISSN: 0261-4189
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Journal of Cell Biology, 2013, ISSN: 0021-9525
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Journal of Medicinal Chemistry, 2013, ISSN: 0022-2623
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Journal of Clinical Pharmacology, 2013, ISSN: 0091-2700
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Journal of Biological Chemistry, 2013, ISSN: 0021-9258
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Journal of Biological Chemistry, 2013, ISSN: 0021-9258
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Nature Immunology, 2013, ISSN: 1529-2908
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Nature Genetics, 2013, ISSN: 1061-4036
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Nature, 2013, ISSN: 0028-0836
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Journal of Biological Chemistry, 2012, ISSN: 0021-9258
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Journal of Medicinal Chemistry, 2012, ISSN: 0022-2623
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Journal of Biological Chemistry, 2012, ISSN: 0021-9258
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Nature Chemical Biology, 2012, ISSN: 1552-4450
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Journal of Pharmacology and Experimental Therapeutics, 2012, ISSN: 0022-3565
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Pharmaceutical Research, 2012, ISSN: 0724-8741
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Journal of Biological Chemistry, 2012, ISSN: 0021-9258
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Molecular Cell, 2012,
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American Journal of Human Genetics, 2012, ISSN: 0002-9297
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Nature Reviews, 2012, ISSN: 1474-1733
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New England Journal of Medicine, 2012, ISSN: 0028-4793
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Proceedings of the National Academy of Sciences, 2012, ISSN: 0027-8424
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Journal of Immunological Methods, 2012, ISSN: 0022-1759
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Nature Genetics, 2012, ISSN: 1061-4036
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The Lancet Oncology, 2012, ISSN: 1470-2045
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Science Translational Medicine, 2012, ISSN: 1946-6234
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Nature, 2012, ISSN: 0028-0836
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Science, 2012, ISSN: 0036-8075
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Clinical Pharmacology and Therapeutics, 2012, ISSN: 0009-9236
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Journal of Medicinal Chemistry, 2012, ISSN: 0022-2623
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PloS ONE, 2010, ISSN: 1932-6203
Gong, Y.; Bourhis, E.; Chiu, C.; Stawicki, S.; DeAlmeida, V.; Liu, B.; Phamluong, K.; Cao, T.; Carano, R.; Ernst, J.; Solloway, M.; Rubinfeld, B.; Hannoush, R.; Wu, Y.; Polakis, P.; Costa, M.
Evaluation of Heterophilic Antibody Blocking Agents in Reducing False Positive Interference in Immunoassays for IL-17AA, IL-17FF, and IL-17AF.
Journal of Immunological Methods, 2010, ISSN: 1872-7905
Deforge, L.; Loyet, K.; Delarosa, D.; Chinn, J.; Zamanian, F.; Chuntharapai, A.; Lee, J.; Hass, P.; Wei, N.; Townsend, M.; Wang, J.; Wong, W.L.
Science Translational Medicine, 2010, ISSN: 1946-6242
Wallin, J.; Guan, J.; Prior, W.-W.; Edgar, K.; Kassees, R.; Sampath, D.; Belvin, M.; Friedman, L.
Neuron, 2010, ISSN: 0896-6273
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Proteolysis-induced N-terminal Ectodomain Shedding of the Integral Membrane Glycoprotein CUB Domain-containing Protein 1 (CDCP1) Is Accompanied by Tyrosine Phosphorylation of Its C-terminal Domain and Recruitment of Src and PKCδ.
Journal of Biological Chemistry, 2010, ISSN: 0021-9258
He, Y.; Wortmann, A.; Burke, L.; Reid, J.; Adams, M.; Abdul-Jabbar, I.; Quigley, J.; Leduc, R.; Kirchhofer, D.; Hooper, J.
Journal of Biological Chemistry, 2010, ISSN: 0021-9258
Fiorillo, E.; Orru, V.; Stanford, S.; Liu, Y.; Salek, M.; Rapini, N.; Schenone, A.; Saccucci, P.; Delogu, L.; Angelini, F.; Bitti, M.L.M.; Schmedt, C.; Chan, A.C.; Acuto, O.; Bottini, N.
Science, 2010, ISSN: 1095-9203
Singh, H.; Demarco, I.
PLoS ONE, 2010, ISSN: 1932-6203
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Journal of Experimental Medicine, 2010, ISSN: 0022-1007
Broz, P.; Newton, K.;Lamkanfi, M.; Mariathasan, S.; Dixit, V.; Monack, D.
Neuron, 2010, ISSN: 0896-6273
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Cell Host & Microbe, 2010, ISSN: 1931-3128
Lamkanfi, M.; Dixit, V.
Science, 2010, ISSN: 1095-9203
Mellman, I.; Clausen, B.
Blood, 2010, ISSN: 1528-0020
Dornan, D.; Spleiss, O.; Yeh, R.; Duchateau-Nguyen, G.; Dufour, A.; Zhi, J.; Robak, T.; Moiseev, S.I.; Dmoszynska, A.; Solal-Celigny, P.; Warzocha, K.; Loscertales, J.; Catalano, J.; Afanasiev, B.; Larratt, L.; Rossiev, V.A.; Bence-Bruckler, I.; Geisler, C.H.; Montillo, M.; Wenger, M.K.; Weisser, M.
Nature, 2010, ISSN: 1476-4687
Kan, Z.; Jaiswal, B.; Stinson, J.; Janakiraman, V.; Bhatt, D.; Stern, H.; Yue, P.; Haverty, P.; Bourgon, R.; Zheng, J.; Moorhead, M.; Chaudhuri, S.; Tomsho, L.; Peters, B.; Pujara, K.; Cordes, S.; Davis, D.; Carlton, V.; Yuan, W.; Li, L.; Wang, W.; Eigenbrot, C.; Kaminker, J.; Eberhard, D.; Waring, P.; Schuster, S.; Modrusan, Z.; Zhang, Z.; Stokoe, D.; de Sauvage, F.; Faham, M.; Seshagiri, S.
Proceedings of the National Academy of Sciences, 2010, ISSN: 1091-6490
Eigenbrot, C.; Ultsch, M.; Dubnovitsky, A.; Abrahmsen, L.; Haerd, T.
Nature Genetics, 2010, ISSN: 1546-1718
Ferreira, R.; Pan-Hammarstroem, Q.; Graham, R.; Gateva, V.; Fontan, G.; Lee, A.; Ortmann, W.; Urcelay, E.; Fernandez-Arquero, M.; Nunez, C.; Jorgensen, G.; Ludviksson, B.; Koskinen, S.; Haimila, K.; Clark, H.; Klareskog, L.; Gregersen, P.; Behrens, T.; Hammarstroem, L.
EMBO Reports, 2010, ISSN: 1469-221X
Reiter, J.; de Sauvage, F.
Nature Immunology, 2010, ISSN: 1529-2908
Hodson, D.; Janas, M.; Galloway, A.; Bell, S.; Andrews, S.; Li, C.; Pannell, R.; Siebel, C.; Mac Donald, H.R.; De Keersmaecker, K.; Ferrando, A.; Grutz, G.; Turner, M.
Molecular Cell, 2010, ISSN: 1097-4164
Matsumoto, M.; Wickliffe, K.; Dong, K.; Yu, C.; Bosanac, I.; Bustos, D.; Phu, L.; Kirkpatrick, D.; Hymowitz, S.; Rape, M.; Kelley, R.; Dixit, V.
Nature Biotechnology, 2010, ISSN: 1087-0156
Domann, P.; Akashi, S.; Barbas, C.; Huang, L.; Lau, W.; Legido-Quigley, C.; McClean, S.; Neusuess, C.; Perrett, D.; Quaglia, M.; Rapp, E.; Smallshaw, L.; Smith, N.; Smyth, W.F.; Taylor, C.
Rituximab versus Cyclophosphamide for ANCA-Associated Vasculitis.
New England Journal of Medicine, 2010, ISSN: 0028-4793
Stone, J.; Merkel, P.; Spiera, R.; Seo, P.; Langford, Carol, A.; Hoffman, G.; Kallenberg, C.; St. Clair, E.W.; Turkiewicz, A.; Tchao, N.; Webber, L.; Ding, L.; Sejismundo, L.; Mieras, K.; Weitzenkamp, D.; Ikle, D.; Seyfert-Margolis, V.; Mueller, M.; Brunetta, P.; Allen, N.; Fervenza, F.; Geetha, D.; Keogh, K.; Kissin, E.; Monach, P.; Peikert, T.; Stegeman, C.; Ytterberg, S.; Specks, U.
Journal of Clinical Investigation, 2010, ISSN: 0021-9738
Cao, S.; Yaqoob, U.; Das, A.; Shergill, U.; Jagavelu, K.; Huebert, R.; Routray, C.; Abdelmoneim, S.; Vasdev, M.; Leof, E.; Charlton, M.; Watts, R.; Mukhopadhyay, D.; Shah, V.
Nature, 2010, ISSN: 0028-0836
Surolia, I.; Pirnie, S.; Chellappa, V.; Taylor, K.; Cariappa, A.; Moya, J.; Liu, H.; Bell, D.; Driscoll, D.; Diederichs, S.; Haider, K.; Netravali, I.; Le, S.; Elia, R.; Dow, E.; Lee, A.; Freudenberg, J.; De Jager, P.; Chretien, Y.; Varki, A.; MacDonald, M.; Gillis, T.; Behrens, T.; Bloch, D.; Collier, D.; Korzenik, J.; Podolsky, D.; Hafler, D.; Murali, M.; Sands, B.; Stone, J.; Gregersen, P.; Pi
Developmental Cell, 2010, ISSN: 1534-5807
Hao, J.; Adler, C.; Mebane, L.; Gertler, F.; Bargmann, C.; Tessier-Lavigne, M.
Cell, 2010, ISSN: 0092-8674
Jin, H.; White, S.R.; Shida, T.; Schulz, S.; Aguiar, M.; Gygi, S.P.; Bazan, J.F.; Nachury, M.V.
Nature Immunology, 2010, ISSN: 1529-2908
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Pharmaceutical Research, 2010, ISSN: 1573-904X
Chang, J.; Xiao, N.; Zhu, M.; Zhang, J.; Hoff, E.; Russell, S.; Katta, V.; Shire, S.
Role of Myeloid and Other Stromal Cell Types in Tumor Angiogenesis.
Blood, 2009, ISSN: 0006-4971
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FC-Gamma Receptor (FCGR) 2A and 3A Polymorphisms Do Not Influence the Outcome of Relapsed or Refractory CLL Patients Treated with Rituximab, Fludarabine, and Cyclophosphamide (R-FC) or Fludarabine, and Cyclophosphamide (FC) Alone.
Blood, 2009, ISSN: 0006-4971
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The PI3K Inhibitor GDC-0941 Induces Growth Arrest and Apoptosis of Acute Myeloid Leukemia Cells.
Blood, 2009, ISSN: 0006-4971
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Blood, 2009, ISSN: 0006-4971
Li, J.; Zhi, J.; Wenger, M.K.; Valente, N.; Visich, J.
The PI3K Inhibitor GDC-0941 Synergizes with Standard of Care Therapies to Induce Growth Inhibition and Apoptosis of Multiple Myeloma Cells.
Blood, 2009, ISSN: 0006-4971
Munugalavadla, V.; Berry, L.; Du, C.; Mariathasan, S.; Slaga, D.; Sun, L.; Chesi, M.; Bergsagel, P.L.; Ebens, A.J.
American Journal of Pathology, 2010, ISSN: 0002-9440
Yan, Q.; Yao, D.; Wei, L.; Huang, Y.; Myers, J.; Zhang, L.; Xin, W.; Shim, J.; Man, Y.; Petryniak, B.; Gerson, S.; Lowe, J.; Zhou, L.
Nature Biotechnology, 2010, ISSN: 1546-1696
Tang, T.; Li, L.; Tang, J.; Li, Y.; Lin, W.Y.; Martin, F.; Grant, D.; Solloway, M.; Parker, L.; Ye, W.; Forrest, W.; Ghilardi, N.; Oravecz, T.; Platt, K.; Rice, D.; Hansen, G.; Abuin, A.; Eberhart, D.; Godowski, P.; Holt, K.; Peterson, A.; Zambrowicz, B.; de Sauvage, F.
Cell, 2010, ISSN: 0092-8674
Li, Z.; Jo, J.; Jia, J.M.; Lo, S.C.; Whitcomb, D.J.; Jiao, S.; Cho, K.; Sheng, M.
Nature Chemical Biology, 2010, ISSN: 1552-4469
Hannoush, R,; Sun, J.
Blood, 2010, ISSN: 1528-0020
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Journal of Clinical Investigation, 2010, ISSN: 1558-8238
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Journal of Immunological Methods, 2010, ISSN: 0022-1759
McCutcheon, K.; Quarmby, V.; Song, A.
Journal of Clinical Oncology, 2010, ISSN: 0732-183X
Russell, S.; Blackwell, K.; Lawrence, J.; Pippen, J. E. Jr.; Roe, M.; Wood, F.; Paton, V.; Holmgren, E; Mahaffey, K.
Proceedings of the National Academy of Sciences, 2010, ISSN: 0027-8424
Jones, J.; Kayagaki, N.; Broz, P.; Henry, T.; Newton, K. O'Rourke, K.; Chan, S.; Dong, J.; Qu, Y.; Roose-Girma, M.; Dixit, V.; Monack, D.
Drug Metabolism and Disposition, 2010, ISSN: 1521-009X
Salphati, L.; Wong, H.; Belvin, M.; Bradford, D.; Edgar, K.; Prior, W.; Sampath, D.; Wallin, J.
Cancer Cell, 2010, ISSN: 1535-6108
Noushmehr, H.; Weisenberger, D.J.; Diefes, K.; Phillips, H.S.; Pujara, K.; Berman, B.P.; Pan, F.; Pelloski, C.E.; Sulman, E.P.; Bhat, K.P.; Verhaak, R.G.W.; Hoadley, K.A.; Hayes, D.N.; Perou, C.M.; Schmidt, H.K.; Ding, L.; Wilson, R.K.; Van Den Berg, D.; Shen, H.; Bengtsson, H.; Neuvial, P.; Cope, L.M.; Buckley, J.; Herman, J.G.; Baylin, S.B.; Laird, P.W.; Aldape, K.
Nature, 2010, ISSN: 1476-4687
Lee, W.; Jiang, Z.; Liu, J.; Haverty, P.; Guan, Y.; Stinson, J.; Yue, P.; Zhang, Y.; Pant, K.; Bhatt, D.; Ha, C.; Johnson, S.; Kennemer ,M.; Mohan, S.; Nazarenko, I.; Watanabe, C.; Sparks, A.; Shames, D.; Gentleman, R.; de Sauvage, F.; Stern, H.; Pandita, A.; Ballinger, D.; Drmanac, R.; Modrusan, Z.; Seshagiri, S.; Zhang, Z.
Journal of Biological Chemistry, 2010, ISSN: 1083-351X
Maun, H.R.; Wen, X.; Lingel, A.; de Sauvage, F.J.; Lazarus, R.A.; Scales, S.J.; Hymowitz, S.G.
Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis.
Nature, 2010, ISSN: 0028-0836
Baranzini, S.; Mudge, J.; van Velkinburgh, J.; Khankhanian, P.; Khrebtukova, I.; Miller, N.; Zhang, L.; Farmer, A.; Bell, C.; Kim, R.; May, G.; Woodward, J.; Caillier, S.; McElroy, J.; Gomez, R.; Pando, M.; Clendenen, L.; Ganusova, E.; Schilkey, F.; Ramaraj, T.; Khan, O.; Huntley, J.; Luo, S.; Kwok, P.; Wu, T.; Schroth, G.; Oksenberg, J.; Hauser, S.; Kingsmore, S.
Nature Cell Biology, 2010, ISSN: 1476-4679
Dixit, V.
PLoS Pathogens, 2010, ISSN: 1553-7374
Carlsson, F.; Kim, J.; Dumitru, C.; Barck, K.; Carano, R.; Sun, M.; Diehl, L.; Brown, E.
Journal of Clinical Oncology, 2010, ISSN: 1527-7755
Herbst, R.; Eckhardt, S.; Kurzrock, R.; Ebbinghaus, S.; O'Dwyer, P.; Gordon, M.; Novotny, W.; Goldwasser, M.; Tohnya, T.; Lum, B.; Ashkenazi, A. Jubb, A.; Mendelson, D.
Nature Biotechnology, 2010, ISSN: 1546-1696
Singh, M.; Lima, A.; Molina, R.; Hamilton, P.; Clermont, A.; Devasthali, V.; Thompson, J.; Cheng, J.H.; Bou-Reslan, H.; Ho, C.C.K.; Cao, T., Lee, C., Nannini, M.; Fuh, G.; Carano, R.; Koeppen, H.; Yu, R.; Forrest, W.; Plowman, G.; Johnson, Leisa
Journal of Clinical Oncology, 2010, ISSN: 1527-7755
Krop, I.; Beeram, M.; Modi, S.; Jones, S.; Holden, S.; Yu, W.; Girish, S.; Tibbitts, J.; Yi, J.-H.; Sliwkowski, M.; Jacobson, F.; Lutzker, S.; Burris, H.
Journal of Clinical Oncology, 2010, ISSN: 0732-183X
Friedman, H.; Prados, M.; Wen, P.; Mikkelsen, T.; Schiff, D.; Abrey, L.; Yung, W.; Paleologos, N.; Nicholas, M.; Jensen, R.; Vredenburgh, J.; Huang, J.; Zheng, M.; Cloughesy, T.
Journal of Biological Chemistry, 2010, ISSN: 0021-9258
Jackman, J.; Chen, Y.; Huang, A.; Moffat, B.; Scheer, J.; Leong, S.; Lee, W.; Zhang, J.; Sharma, N.; Lu, Y.; Iyer, S.; Shields, R.; Chiang, N.; Bauer, M.; Waley, D.; Roose-Girma, M.; Vandlen, R.; Yansura, D.; Wu, Y.; Wu, L.
American Journal of Pathology, 2010, ISSN: 0002-9440
Mura, M.; Binnie, M.; Han, B.; Li, C; Andrade, C.; Shiozaki, A.; Zhang, Y.; Ferrara, N.; Hwang, D.; Waddell, T.; Keshavjee, S.; Liu, M.
PLoS Biology, 2010, ISSN: 1544-9173
Renier, N.; Schonewille, M.; Giraudet, F.; Badura, A.; Tessier-Lavigne, M.; Avan, P.; de Zeeuw, C.; Chedotal, A.
Drug Metabolism and Disposition, 2010, ISSN: 0090-9556
Wong, H.; Theil, F.-P; Cui, Y; Marsters, J.; Khojasteh S.C.; Vernillet, L.; La, H.; Song, X.; Wang, H.; Morinello, E.; Deng, Y.; Hop, C.
Cancer Therapy Reform
Science, 2010, ISSN: 0036-8075
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Journal of Clinical Oncology, 2010, ISSN: 1527-7755
Pollyea, D.A.; Brown, J.M.Y.; Horning, S.J.
Science Signaling, 2009, ISSN: 1937-9145
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Cancer Cell, 2010, ISSN: 1878-3686
Chen, R.; Nishimura, M.C.; Bumbaca, S.M.; Kharbanda, S.; Forrest, W.F.; Kasman, I.M.; Greve, J.M.; Soriano, R.H.; Gilmour, L.L.; Rivers, C.S.; Modrusan, Z.; Nacu, S.; Guerrero, S.; Edgar, K.A.; Wallin, J.J.; Lamszus, K.; Westphal, M.; Heim, S.; James, C.D.; VandenBerg, S.R.; Costello, J.F.; Moorefield, S.; Cowdrey, C.J.; Prados, M.; Phillips, H.S.
Journal of Clinical Oncology, 2010, ISSN: 0732-183X
Robak, T.; Dmoszynska, A.; Solal-Celigny, P.; Warzocha, K.; Loscertales, J.; Catalano, J.; Afanasiev, B.V.; Larratt, L.; Geisler, C.H.; Montillo, M.; Zyuzgin, I.; Ganly, P.S.; Dartigeas, C.; Rosta, A.; Maurer, J.; Mendila, M.; Saville, M.W.; Valente, N.; Wenger, M.K.; Moiseev, S.I.
Nature Cell Biology, 2010, ISSN: 1465-7392
Pereg, Y.; Liu, B.; O'Rourke, K.; Sagolla, M.; Dey, A.; Komuves, L.; French, D.; Dixit, V.
Chemical Research in Toxicology, 2010, ISSN: 1520-5010
Driscoll, J.P.; Aliagas, I.; Harris, J.J.; Halladay, J.S.; Khatib-Shahidi, S.; Deese, A.; Segraves, N.; Khojasteh-Bakht, S.C.
Proceedings of the National Academy of Sciences, 2010, ISSN: 1091-6490
Wong, K.; Valdez, P.; Tan, C.; Yeh, S.; Hongo, J.; Ouyang, W.
Nature, 2010, ISSN: 1476-4687
Wu, Y.; Cain-Hom, C.; Choy, L.; Hagenbeek, T.J.; de Leon, G.P.; Chen, Y.; Finkle, D.; Venook, R.; Wu, X.; Ridgway, J.; Schahin-Reed, D.; Dow, G.J.; Shelton, A.; Stawicki, S.; Watts, R.J.; Zhang, J.; Choy, R.; Howard, P.; Kadyk, L.; Yan, M.; Zha, J.; Callahan, C.A.; Hymowitz, S.G.; Siebel, C.W.
Biochemistry, 2010, ISSN: 1520-4995
Lovitt, B.; Vanderporten, E.C.; Sheng, Z.; Zhu, H.; Drummond, J.; Liu, Y.
Cell, 2010, ISSN: 1097-4172
Bais, C.; Wu, X.; Yao, J.; Yang, S.; Crawford, Y.; McCutcheon, K.; Tan, C.; Kolumam, G.; Vernes, J.M.; Eastham-Anderson, J.; Haughney, P.; Kowanetz, M.; Hagenbeek, T.; Kasman, I.; Reslan, H.B.; Ross, J.; Van Bruggen, N.; Carano, R.A.; Meng, Y.J.; Hongo, J.A.; Stephan, J.P.; Shibuya, M.; Ferrara, N.
Current Opinion in Structural Biology, 2010, ISSN: 1879-033X
Tesar, D.B.; Bjorkman, P.J.
PLoS Pathogens, 2010, ISSN: 1553-7366
Stoddart, C.A.; Keir, M.E.; McCune, J.M.
Nature, 2010, ISSN: 1476-4687
Chung, I.; Akita, R.; Vandlen, R.; Toomre, D.; Schlessinger, J.; Mellman, I.
Pharmaceutical Research, 2010, ISSN: 0724-8741
Ji, J.Y.A.; Liu, J.; Shire, S.J.; Kamerzell, T.J.; Hong, S.; Billeci, K.; Shen, Y.; Wang, Y.J.
Journal of Clinical Investigation, 2010, ISSN: 0021-9738
O'Toole, J.F.; Liu, Y.J.; Davis, E.E.; Westlake, C.J.; Attanasio, M.; Otto, E.A.; Seelow, D.; Nurnberg, G.; Becker, C.; Nuutinen, M.; Karppa, M.; Ignatius, J.; Uusimaa, J.; Pakanen, S.; Jaakkola, E.; van den Heuvel, L.P.; Fehrenbach, H.; Wiggins, R.; Goyal, M.; Zhou, W.B.; Wolf, M.T.F.; Wise, E.; Helou, J.; Allen, S.J.; Murga-Zamalloa, C.A.; Hildebrandt, F.; et al.
Nature, 2010, ISSN: 1476-4687
Hatzivassiliou, G.; Song, K.; Yen, I.; Brandhuber, B.J.; Anderson, D.J.; Alvarado, R.; Ludlam, M.J.; Stokoe, D.; Gloor, S.L.; Vigers, G.; Morales, T.; Aliagas, I.; Liu, B.; Sideris, S.; Hoeflich, K.P.; Jaiswal, B.S.; Seshagiri, S.; Koeppen, H.; Belvin, M.; Friedman, L.S.; Malek, S.
Nature Structural & Molecular Biology, 2010, ISSN: 1545-9985
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Proceedings of the National Academy of Sciences, 2010, ISSN: 0027-8424
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Blood, 2010, ISSN: 0006-4971
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Journal of Experimental Medicine, 2009, ISSN: 0022-1007
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Journal of Cell Biology, 2010, ISSN: 0021-9525
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Journal of Experimental Medicine, 2010, ISSN: 1540-9538
Xi, H.; Katschke, K.J. Jr.; Helmy, K.Y.; Wark, P.A.; Kljavin, N.; Clark, H.; Eastham-Anderson, J.; Shek, T.; Roose-Girma, M.; Ghilardi, N.; van Lookeren Campagne, M.
PLoS ONE, 2010, ISSN: 1932-6203
Liu, B.Y.; Soloviev, I.; Chang, P.; Lee, J.; Huang, X.; Zhong, C.; Ferrara, N.; Polakis, P.; Sakanaka, C.
Cell, 2010, ISSN: 0092-8674
Lichtenberger, B.M.; Tan, P.K.; Niederleithner, H.; Ferrara, N.; Petzelbauer, P.; Sibilia, M.
Developmental Cell, 2010, ISSN: 1534-5807
Camerer, E.; Barker, A.; Duong, D.N.; Ganesan, R.; Kataoka, H.; Cornelissen, I.; Darragh, M.R.; Hussain, A.; Zheng, Y.W.; Srinivasan, Y.; Brown, C.; Xu, S.M.; Regard, J.B.; Lin, C.Y.; Craik, C.S.; Kirchhofer, D.; Coughlin, S.R.
Journal of Medicinal Chemistry, 2010, ISSN: 1520-4804
Sutherlin, D.P.; Sampath, D.; Berry, M.; Castanedo, G.; Chang, Z.; Chuckowree, I.; Dotson, J.; Folkes, A.; Friedman, L.; Goldsmith, R.; Heffron, T.; Lee, L.; Lesnick, J.; Lewis, C.; Mathieu, S.; Nonomiya, J.; Olivero, A.; Pang, J.; Prior, W.W.; Salphati, L.; Sideris. S.; Tian, Q.; Tsui, V.; Wan, N.C.; Wang, S.; Wiesmann, C.; Wong, S.; Zhu, B.Y.
Nature, 2010, ISSN: 1476-4687
Yan, M.; Callahan, C.A.; Beyer, J.C.; Allamneni, K.P.; Zhang, G.; Ridgway, J.B.; Niessen, K.; Plowman, G.D.
PLoS ONE, 2010, ISSN: 1932-6203
Esue, O.; Rupprecht, L.; Sun, S.X.; Wirtz, D.
Journal of Experimental Medicine, 2010, ISSN: 1540-9538
Crellin, N.K.; Trifari, S.; Kaplan, C.D.; Cupedo, T.; Spits, H.
Journal of Biological Chemistry, 2010, ISSN: 1083-351X
Bourhis, E.; Tam, C.; Franke, Y.; Bazan, J.F.; Ernst, J.; Hwang, J.; Costa, M.; Cochran, A.G.; Hannoush, R.N.
Arthritis & Rheumatism, 2009, ISSN: 0004-3591
Bauer, J.W.; Petri, M.; Batliwalla, F.M.; Koeuth, T.; Wilson, J.; Slattery, C.; Panoskaltsis-Mortari, A.; Gregersen, P.K.; Behrens, T.W.; Baechler EC
Journal of Biological Chemistry, 2009, ISSN: 0021-9258
Li, B.; Xi, H.K.; Diehl, L.; Lee, W.P.; Sturgeon, L.; Chinn, J.; DeForge, L.; Kelley, R.F.; Wiesmann, C.; Campagne, M.V.; Sidhu, S.S.
Characterization of oligosaccharides in recombinant tissue plasminogen activator produced in Chinese Hamster Ovary Cells: two decades of analytical technology development.
Analytical Chemistry, 2009, ISSN: 0003-2700
Borisov, O.V.; Field, M.; Ling, V.T.; Harris, R.J.
Cancer Cell, 2009, ISSN: 1878-3686
Jaiswal, B.S.; Janakiraman, V.; Kljavin, N.M.; Chaudhuri, S.; Stern, H.M.; Wang, W.; Kan, Z.; Dbouk, H.A.; Peters, B.A.; Waring, P.; Dela Vega, T.; Kenski, D.M.; Bowman, K.K.; Lorenzo, M.; Li, H.; Wu, J.; Modrusan, Z.; Stinson, J.; Eby, M.; Yue, P.; Kaminker, J.S.; de Sauvage, F.J.; Backer, J.M.; Seshagiri, S.
Plos Biology, 2009, ISSN: 1544-9173
Tonikian, R.; Xin, X.F.; Toret, C.P.; Gfeller, D.; Landgraf, C.; Panni, S.; Paoluzi, S.; Castagnoli, L.; Currell, B.; Seshagiri, S.; Yu, H.Y.; Winsor, B.; Vidal, M.; Gerstein, M.B.; Bader, G.D.; Volkmer, R.; Cesareni, G.; Drubin, D.G.; Kim, P.M.; Sidhu, S.S.; Boone, C.
PLoS Genetics, 2009, ISSN: 1553-7390
Barcellos, L.F.; May, S.L.; Ramsay, P.P.; Quach, H.L.; Lane, J.A.; Nititham, J.; Noble, J.A.; Taylor, K.E.; Quach, D.L.; Chung, S.A.; Kelly, J.A.; Moser, K.L.; Behrens, T.W.; Seldin, M.F.; Thomson, G.; Harley, J.B.; Gaffney, P.M.; Criswell, L.A.
Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors: insight into heterotrimeric IL-1 signaling complexes.
Structure, 2009, ISSN: 1878-4186
Lingel, A.; Weiss, T.M.; Niebuhr, M.; Pan, B.; Appleton, B.A.; Wiesmann, C.; Bazan, J.F.; Fairbrother, W.J.
Multivariate analysis of the sequence dependence of asparagine deamidation rates in peptides.
Pharmaceutical Research, 2009, ISSN: 0724-8741
Kosky, A.A.; Dharmavaram, V.; Ratnaswamy, G.; Manning, M.C.
Multiproduct high-resolution monoclonal antibody charge variant separations by pH gradient ion-exchange chromatography.
Analytical Chemistry, 2009, ISSN: 1520-6882
Farnan, D.; Moreno, G.T.
Carboxylate-dependent gelation of a monoclonal antibody.
Pharmaceutical Research, 2009, ISSN: 0724-8741
Esue, O.; Kanai, S.; Liu, J.; Patapoff, T.W.; Shire, S.J.
Smoothened mutation confers resistance to a hedgehog pathway inhibitor in medulloblastoma.
Science, 2009, ISSN: 0036-8075
Yauch, R.L.; Dijkgraaf, G.J.P.; Alicke, B.; Januario,T.; Ahn, C.P.; Holcomb, T.; Pujara, K.; Stinson, J.; Callahan, C.A.; Tang, T.; Bazan, J.F.; Kan, Z.; Seshagiri, S.; Hann, C.L.; Gould, S.E.; Low, J.A.; Rudin, C.M.; de Sauvage, F.J.
Masking MALT1: the paracaspase's potential for cancer therapy.
Journal of Experimental Medicine, 2009, ISSN: 1540-9538
Vucic, D.; Dixit, V.M.
Formulation and manufacturability of biologics.
Current Opinion in Biotechnology, 2009, ISSN: 1879-0429
Shire, S.J.
Retinoic acid from the meninges regulates cortical neuron generation.
Cell, 2009, ISSN: 0092-8674
Siegenthaler, J.A.; Ashique, A.M.; Zarbalis, K.; Patterson, K.P.; Hecht, J.H.; Kane, M.A.; Folias, A.E.; Choe, Y.; May, S.R.; Kume, T.; Napoli, J.L.; Peterson, A.S.; Pleasure, S.J.
X chromosome-linked inhibitor of apoptosis regulates cell death induction by proapoptotic receptor agonists.
Journal of Biological Chemistry, 2009, ISSN: 1083-351X
Varfolomeev, E.; Alicke, B.; Elliott, J.M.; Zobel, K.; West, K.; Wong, H.; Scheer, J.M.; Ashkenazi, A.; Gould, S.E.; Fairbrother, W.J.; Vucic, D.
Role of sensitivity analyses in assessing progression-free survival in late-stage oncology trials.
Journal of Clinical Oncology, 2009, ISSN: 1527-7755
Bhattacharya, S.; Fyfe, G.; Gray, R.J.; Sargent, D.J.
Regulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110 alpha and are disrupted in oncogenic p85 mutants.
Proceedings of the National Academy of Sciences, 2009, ISSN: 0027-8424
Wu, H.Y.; Shekar, S.C.; Flinn, R.J.; El-Sibai, M.; Jaiswal, B.S.; Sen, K.I.; Janakiraman, V.; Seshagiri, S.; Gerfen, G.J.; Girvin, M.E.; Backer, J.M.
Identification of codon-specific serine to asparagine mistranslation in recombinant monoclonal antibodies by high-resolution mass spectrometry.
Analytical Chemistry, 2009, ISSN: 1520-6882
Yu, X.C.; Borisov, O.V.; Alvarez, M.; Michels, D.A.; Wang, Y.J.; Ling, V.
Novel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins.
Journal of Biological Chemistry, 2009, ISSN: 0021-9258
Lee, E.F.; Fedorova, A.; Zobel, K.; Boyle, M.J.; Yang, H.; Perugini, M.A.; Colman, P.M.; Huang, D.C.S.; Deshayes, K.; Fairlie, W.D.
Safety of bevacizumab in patients with non-small-cell lung cancer and brain metastases.
Journal of Clinical Oncology, 2009, ISSN: 0732-183X
Socinski, M.A.; Langer, C.J.; Huang, J.E.; Kolb, M.M.; Compton, P.; Wang, L.; Akerley, W.
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.
Nature Genetics, 2009, ISSN: 1061-4036
Gateva, V.; Sandling, J.K.; Hom, G.; Taylor, K.E.; Chung, S.A.; Sun, X.; Ortmann, W.; Kosoy, R.; Ferreira, R.C.; Nordmark, G.; Gunnarsson, I.; Svenungsson, E.; Padyukov, L.; Sturfelt, G.; Jonsen, A.; Bengtsson, A.A.; Rantapaa-Dahlqvist, S.; Baechler, E.C.; Brown, E.E.; Alarcon, G.S.; Edberg, J.C.; Ramsey-Goldman, R.; McGwin, G.; Reveille, J.D.; Vila, L.M.; Graham, R.R.; et al.
PLoS ONE, 2009, ISSN: 1932-6203
Lee, W.; Zhang, Y.; Mukhyala, K.; Lazarus, R.A.; Zhang, Z.
Structure, 2009, ISSN: 1878-4186
Ganesan, R.; Eigenbrot, C.; Wu, Y.; Liang, W.C.; Shia, S.; Lipari, M.T.; Kirchhofer, D.
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome.
Journal of Cell Biology, 2009, ISSN: 1540-8140
Lamkanfi, M.; Mueller, J.L.; Vitari, A.C.; Misaghi, S.; Fedorova. A.; Deshayes, K.; Lee, W.P.; Hoffman, H.M.; Dixit, V.M.
Antigen choice in adoptive T-cell therapy of cancer.
Current Opinion in Immunology, 2009, ISSN: 0952-7915
Offringa, R.
Local guidance of emerging vessel sprouts requires soluble Flt-1
Developmental Cell, 2009, ISSN: 1534-5807
Chappell, J.C.; Taylor, S.M.; Ferrara, N.; Bautch, V.L.
A modular platform for the rapid site-specific radiolabeling of proteins with 18F exemplified by quantitative positron emission tomography of human epidermal growth factor receptor 2.
Journal of Medicinal Chemistry, 2009, ISSN: 1520-4804
Gill, H.S.; Tinianow, J.N.; Ogasawara, A.; Flores, J.E.; Vanderbilt, A.N.; Raab, H.; Scheer, J.M.; Vandlen, R.; Williams, S.P.; Marik, J.
Techniques for time-efficient isolation of human skin dendritic cell subsets and assessment of their antigen uptake capacity.
Journal of Immunological Methods, 2009, ISSN: 0022-1759
Bond, E.; Adams, W.C.; Smed-Sorensen, A.; Sandgren, K.J.; Perbeck, L.; Hofmann, A.; Andersson, J.; Lore, K.
Inhibition of the hedgehog pathway in advanced basal-cell carcinoma.
New England Journal of Medicine, 2009, ISSN: 0028-4793
Von Hoff, D.D.; LoRusso, P.M.; Rudin, C.M.; Reddy, J.C.; Yauch, R.L.; Tibes, R.; Weiss, G.J.; Borad, M.J.; Hann, C.L.; Brahmer, J.R.; Mackey, H.M.; Lum, B.L.; Darbonne, W.C.; Marsters, J.C.; de Sauvage, F.J.; Low J.A.
Brief Report: treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449.
New England Journal of Medicine, 2009, ISSN: 0028-4793
Rudin, C.M.; Hann, C.L.; Laterra, J.; Yauch, R.L.; Callahan, C.A.; Fu, L.; Holcomb, T.; Stinson, J.; Gould, S.E.; Coleman, B.; LoRusso, P.M.; Von Hoff, D.D.; de Sauvage, F.J.; Low, J.A.
Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity.
PLoS ONE, 2009,
Blum, G.; Weimer, R.M.; Edgington, L.E.; Adams, W.; Bogyo, M.
Therapeutic potential of an anti-CD79b antibody-drug conjugate, anti-CD79b-vc-MMAE, for the treatment of non-Hodgkin's lymphoma.
Blood, 2009, ISSN: 1528-0020
Dornan, D.; Bennett, F.; Chen, Y.; Dennis, M.; Eaton D.; Elkins, K.; French, D.; Go, M.A.T.; Jack, A.; Junutula, J.R.; Koeppen, H.; Lau, J.; McBride, J.; Rawstron, A.; Shi, X.; Yu, N.; Yu, S.-F.; Yue, P.; Zheng, B.; Ebens, A.; Polson, A.G.
Structural ties between cholesterol transport and morphogen signaling.
Cell, 2009, ISSN: 1097-4172
Bazan, J.F.; de Sauvage, F.J.
A highly annotated whole-genome sequence of a Korean individual.
Nature, 2009, ISSN: 0028-0836
Kim, J.I.; Ju, Y.S.; Park, H.; Kim, S.; Lee, S.; Yi, J.H.; Mudge, J.; Miller, N.A.; Hong, D.; Bell, C.J.; Kim, H.S.; Chung, I.S.; Lee, W.C.; Lee, J.S.; Seo, S.H.; Yun, J.Y.; Woo, H.N.; Lee, H.; Suh, D.; Lee, S.; Kim, H.J.; Yavartanoo, M.; Kwak, M.; Zheng, Y.; Lee, M.K.; Park, H.; Kim, J.Y.; ... Wu, T.D.; Kim, H.; Yang, K.-S.; ...Kingsmore, S.F.; Seo, J.-S.
European population substructure is associated with mucocutaneous manifestations and autoantibody production in systemic lupus erythematosus.
Arthritis & Rheumatism, 2009, ISSN: 0004-3591
Chung, S.A.; Tian, C.; Taylor, K.E.; Lee, A.T.; Ortmann, W.A.; Hom, G.; Graham, R.R.; Nititham, J.; Kelly, J.A.; Morrisey, J.; Wu, H.; Yin, H.; Alarcon-Riquelme, M.E.; Tsao, B.P.; Harley, J.B.; Gaffney, P.M.; Moser, K.L.; Manzi, S.; Petri, M.; Gregersen, P.K.; Langefeld, C.D.; Behrens, T.W.; Seldin, M.F.; Criswell, L.A.
Investigation of sample preparation artifacts formed during the enzymatic release of N-Linked glycans prior to analysis by capillary electrophoresis.
Analytical Chemistry, 2009, ISSN: 0003-2700
Liu, Y.; Salas-Solano, O.; Gennaro, L.A.
Membrane proteins follow multiple pathways to the basolateral cell surface in polarized epithelial cells.
Journal of Cell Biology, 2009, ISSN: 0021-9525
Farr, G.A.; Hull, M.; Mellman, I.; Caplan, M.J.
FAM29A promotes microtubule amplification via recruitment of the NEDD1-γ-tubulin complex to the mitotic spindle.
Journal of Cell Biology, 2008,
Zhu, H.; Coppinger, J.A.; Jang, C.Y.; Yates J.R.III; Fang, G.
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
Journal of Clinical Oncology, 2009, ISSN: 0732-183X
Zheng, M.; Huang, J.E.; Friedman, H.S.; Prados, M.; Wen, P.Y.; Mikkelsen, T.; Schiff, D.; Abrey, L.E.; Yung, W.K.; Paleologos, N.; Nicholas, M.K.; Jensen, R.; Vrdenburgh, J.; Cloughesy, T.
The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development.
Current Biology, 2009, ISSN: 1879-0445
Endoh-Yamagami, S.; Evangelista, M.; Wilson, D.; Wen, X.; Theunissen, J.-W.; Phamluong, K.; Davis, M.; Scales, S.J.; Solloway, M.J.; de Sauvage, F.J.; Peterson, A.S.
Prostate-specific Klf6 inactivation impairs anterior prostate branching morphogenesis through increased activation of the Shh pathway.
Journal of Biological Chemistry, 2009, ISSN: 0021-9258
Leow, C.C.; Wang, B.; Ross, J.; Chan, S.M.; Zha, J.; Carano, R.A.D.; Frantz, G.; Shen, M.M.; deSauvage, F.J.; Gao, W.-Q.
Breaking into bone biology
Nature Medicine, 2009,
Choi, Y.; Walsh, M.C.; Arron, J.R.
Navigating the deubiquitinating proteome with a CompPASS.[comment].
Cell, 2009, ISSN: 1097-4172
Jackson, P.K.
Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells.
Nature Immunology, 2009, ISSN: 1529-2916
Trifari, S.; Kaplan, C.D.; Tran, E.H.; Crellin, N.K.; Spits, H.
Phosphorylation of a borealin dimerization domain is required for proper chromosome segregation.
Biochemistry, 2009, ISSN: 1520-4995
Bourhis, E.; Lingel, A.; Phung, Q.; Fairbrother, W.J.; Cochran, A.G.
Scalable total synthesis and biological evaluation of haouamine A and its atropisomer.
Journal of the American Chemical Society, 2009, ISSN: 0002-7863
Burns, N.Z.; Krylova, I.N.; Hannoush, R.N.; Baran, P.S.
STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing.
Journal of Experimental Medicine, 2009, ISSN: 0022-1007
Pickert, G.; Neufert, C.; Leppkes, M.; Zheng, Y.; Wittkopf, N.; Warntjen, M.; Lehr, H.A.; Hirth, S.; Weigmann, B.; Wirtz, S.; Ouyang, W.; Neurath, M.F.; Becker, C.
CAPS activity in priming vesicle exocytosis requires CK2 phosphorylation.
Journal of Biological Chemistry, 2009, ISSN: 0021-9258
Nojiri, M.; Loyet, K.M.; Klenchin, V.A.; Kabachinski, G.; Martin, T.F.J.
IL-33 raises alarm.
Immunity, 2009, ISSN: 1097-4180
Lamkanfi, M.; Dixit, V.M.
TSPAN12 regulates retinal vascular development by promoting Norrin but not Wnt-induced FZD4/β-catenin signaling.
Cell, 2009, ISSN: 1097-4172
Junge, H.J.; Yang, S.; Burton, J.B.; Paes, K.; Shu, X.; French, D.M.; Costa, M.; Rice, D.S.; Ye, W.
Journal of Immunological Methods, 2009, ISSN: 1872-7905
Loyet, K.M.; Deng, R.; Liang, W.C.; Wu, Y.; Lowman, H.B.; DeForge, L.E.
Nature Structural & Molecular Biology, 2009, ISSN: 1545-9985
Bosanac, I.; Maun, H.R.; Scales, S.J.; Wen, X.; Lingel, A.; Bazan, J.F.; de Sauvage, F.J.; Hymowitz, S.G.; Lazarus, R.A.
Phase I study of the effect of gastric acid pH modulators on the bioavailability of oral dasatinib in healthy subjects.
Journal of Clinical Pharmacology, 2009, ISSN: 0091-2700
Eley, T.; Luo, F.R.; Agrawal, S.; Sanil, A.; Manning, J.; Li, T.; Blackwood-Chirchir, A.; Bertz, R.
Follicular lymphoma in the United States: First report of the National LymphoCare Study.
Journal of Clinical Oncology, 2009, ISSN: 0732-183X
Friedberg, J.W.; Taylor, M.D.; Cerhan, J.R.; Flowers, C.R.; Dillon, H.; Farber, C.M.; Rogers, E.S.; Hainsworth, J.D.; Wong, E.K.; Vose, J.M.; Zelenetz, A.D.; Link, B.K.
Retrospective evaluation of the clinical and radiographic risk factors associated with severe pulmonary hemorrhage in first-line advanced, unresectable non-small-cell lung cancer treated with carboplatin and paclitaxel plus bevacizumab.
Journal of Clinical Oncology, 2009, ISSN: 0732-183X
Sandler, A.B.; Schiller, J.H.; Gray, R.; Dimery, I.; Brahmer, J.; Samant, M.; Wang, L.I.; Johnson, D.H.
The PRL-1149 G/T polymorphism and rheumatoid arthritis susceptibility.
Arthritis & Rheumatism, 2009, ISSN: 0004-3591
Lee, Y.C.; Raychaudhuri, S.; Cui, J.; De Vivo, I.; Ding, B.; Alfredsson, L.; Padyukov, L.; Costenbader, K.H.; Selelstad, M.; Graham, R.R.; Klareskog, L.; Gregersen, P.K.; Plenge, R.M.; Karlson, E.W.
Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis.
Cell Stem Cell, 2009, ISSN: 1934-5909
Hofmann, I.; Stover, E.H.; Cullen, D.E.; Mao, J.; Morgan, K.J.; Lee, B.H.; Kharas, M.G.; Miller, P.G.; Cornejo, M.G.; Okabe, R.; Armstrong, S.A.; Ghilardi, N.; Gould, S.; de Sauvage, F.J.; McMahon, A.P.; Ghilliland, D.G.
Nature Medicine, 2009, ISSN: 1078-8956
Chiang, E.Y.; Kolumam, G.A.; Yu, X.; Francesco, M.; Ivelja, S.; Peng, I.; Gribling, P.; Shu, J.; Lee, W.P.; Refino, C.J.; Balazs, M.; Paler-Martinez, A.; Nguyen, A.; Young, J.; Barck, K.H.; Carano, R.A.D.; Ferrando, R.; Diehl, L.; Chatterjea, D.; Grogan, J.L.
A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.
Journal of Medicinal Chemistry, 2009, ISSN: 1520-4804
Aliagas-Martin, I.; Burdick, D.; Corson, L.; Dotson, J.; Drummond, J.; Fields, C.; Huang, O.W.; Hunsaker. T.; Kleinheinz, T.; Krueger, E.; Liang, J.; Moffat, J.; Phillips, G.; Pulk, R.; Rawson, T.E.; Ultsch, M.; Walker, L.; Wiesmann, C.; Zhang, B.; Zhu, B.Y.; Cochran, A.G.
Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling.
Cell, 2009, ISSN: 1097-4172
Jin, Z.; Li, Y.; Pitti, R.; Lawrence, D.; Pham, V.C.; Lill, J.R.; Ashkenazi, A.
Combined targeting of BRAF and CRAF or BRAF and P13K effector pathways is required for efficacy in NRAS mutant tumors.
PloS ONE, 2009, ISSN: 1932-6203
Jaiswal, B.S.; Janakiraman, V.; Klavin, N.M.; Eastham-Anderson, J.; Cupp, J.E.; Liang, Y.; Davis, D.P.; Hoeflich, K.P.; Seshagiri, S.
Atg5-independent sequestration of ubiquitinated mycobacteria.
PLoS Pathogens, 2009, ISSN: 1553-7374
Collins, C.A.; De Maziere, A.; van Dijk, S.; Carlsson, F.; Klumperman, J.; Brown, E.J.
Human CD4+ T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function.
Journal of Experimental Medicine, 2009, ISSN: 0022-1007
Haines, C.J.; Giffon, T.D.; Lu, L.-S.; Lu, X.; Tessier-Lavigne, M.; Ross, D.T.; Lewis, D.B.
Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941.
Cancer Cell, 2009, ISSN: 1535-6108
Junttila, T.T.; Akita, R.W.; Parsons, K.; Fields, C.; Lewis Phillips, G.D.; Friedman, L.S.; Sampath, D.; Sliwkowski, M.X.
An analytical system for the characterization of highly heterogeneous mixtures of N-linked oligosaccharides.
Analytical Biochemistry, 2009, ISSN: 1096-0309
Briggs, J.B.; Keck, R.G.; Ma, S.; Lau, W.; Jones, A.J.
How can we improve the translational landscape for a faster cure of type 1 diabetes?
Journal of Clinical Investigation, 2009, ISSN: 0021-9738
vonHerrath, M.; Chan, A.C.
Journal of Clinical Investigation, 2009, ISSN: 1558-8238
Qing, J.; Du, X.; Chen, Y.M.; Chan, P.; Li, H.; Wu, P.; Marsters, S.; Stawicki, S.; Tien, J.; Totpal, K.; Ross, S.; Stinson, S.; Dornan, D.; French, D.; Wang, Q.; Stephan, J.P.; Wu, Y.; Wiesmann, C.; Ashkenazi, A.
The forming limb skeleton serves as a signaling center for limb vasculature patterning via regulation of Vegf.
Development, 2009, ISSN: 0950-1991
Eshkar-Oren, I.; Viukov, S.V.; Salameh, S.; Krief, S.; Oh, C.D.; Akiyama, H.; Gerber, H.P.; Ferrara, N.; Zelzer, E.
The art of making an exit.
Science, 2009, ISSN: 1095-9203
Carlsson, F.; Brown, E.J.
Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as a first-line treatment of metastatic colorectal cancer: results of the TREE study
Journal of Clinical Oncology, 2008, ISSN: 0732-183X
Hochster, H.S.; Hart, L.L.; Ramanathan, R.K.; Childs, B.H.; Hainsworth, J.D.; Cohn, A.L.; Wong, L.; Fehrenbacher, L.; Abubakr, Y.; Saif, M.W.; Schwartzberg, L.; Hedrick, E.
Role of P-glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents.
Drug Metabolism and Disposition, 2008, ISSN: 0090-9556
Garner, C.E.; Solon, E.; Lai, C.-M.; Lin, J.; Luo, G.; Jones, K.; Duan, J.; Decicco, C.P.; Maduskuie, T.; Mercer, S.E.; Gan, L.-S.; Qian, M.; Prakash, S.; Shen, H.-S.; Lee, F.W.
Inhibition of Wnt signaling by Dishevelled PDZ peptides.
Nature Chemical Biology, 2009, ISSN: 1552-4469
Zhang, Y.; Appleton, B.A.; Wiesmann, C.; Lau, T.; Costa, M.; Hannoush, R.N.; Sidhu, S.S.
Death receptor signal transducers: nodes of coordination in immune signaling networks
Nature Immunology, 2009, ISSN: 1529-2916
Wilson, N.S.; Dixit, V.; Ashkenazi, A.
Essential and unique roles of PIP5K-γ and -α in Fcγ receptor-mediated phagocytosis
Journal of Cell Biology, 2009, ISSN: 0021-9525
Mao, Y.S.; Yamaga, M.; Zhu, X.; Wei, Y.J.; Sun, H.Q.; Wang, J.; Yun, M.; Wang, Y.F.; Di Paolo, G.; Bennett, M.; Mellman, I.; Abrams, C.S.; De Camilli, P.; Lu, C.Y.; Yin, H.L.
Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus in a Japanese population
Arthritis & Rheumatism, 2009, ISSN: 0004-3591
Ito, I.; Kawasaki, A.; Ito, S.; Hayashi, T.; Goto, D.; Matsumoto, I.; Tsutsumi, A.; Hom, G.; Graham, R.R.; Takasaki, Y.; Hashimoto, H.; Ohashi, J.; Behrens, T.W.; Sumida, T.;Tsuchiya, N.
Genetic deletion of JAM-C reveals a role in myeloid progenitor generation.
Blood, 2009, ISSN: 1528-0020
Praetor, A,; McBride, J.M,; Chiu, H.; Rangell, L.; Cabote, L.; Lee, W.P.; Cupp, J.; Danilenko, D.M.; Fong, S.
A therapeutic antibody and its antigen form different complexes in serum than in phosphate-buffered saline: a study by analytical ultracentrifugation
Analytical Biochemistry, 2009, ISSN: 1096-0309
Demeule, B.; Shire, S.; Liu, J.
Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site
Science, 2009, ISSN: 0036-8075
Bostrom, J.; Yu, S.-F.; Kan, D.; Appleton, B.A.; Lee, C.V.; Billeci, K.; Man, W.; Peale, F.; Ross, S.; Wiesmann, C.; Fuh, G.
Fatal hepatitis mediated by tumor necrosis factor TNFα requires caspase-8 and involves the BH3-only proteins Bid and Bim.
Immunity, 2009, ISSN: 1074-7613
Kaufmann, T.; Jost, P.J.; Pellegrini, M.; Puthalakath, H.; Gugasyan, R.; Gerondakis, S.; Cretney, E.; Smyth, M.J.; Silke, J.; Hakem, R.; Bouillet, P.; Mak, T.W.; Dixit, V.M.; Strasser A.
APP binds DR6 to trigger axon pruning and neuron death via distinct caspases.
Nature, 2009, ISSN: 0028-0836
Nikolaev, A.; McLaughlin, T.; O'Leary, D.D.M.; Tessier-Lavigne, M.
GPS navigation of the protein-stability landscape.
Nature Biotechnology, 2009, ISSN: 1087-0156
Kirkpatrick, D.S.; Dixit, V.M.
Polar localization of virulence-related Esx-1 secretion in mycobacteria.
PLoS Pathogens, 2009, ISSN: 1553-7374
Carlsson, F.; Joshi, S.A.; Rangell, L.; Brown, E.J.
Journal of Biological Chemistry, 2009, ISSN: 0021-9258
Katschke, K.J., Jr.; Stawicki, S.; Yin, J.; Steffek, M.; Xi, H.; Sturgeon, L.; Hass, P.E.; Loyet, K.; DeForge, L.; Wu, Y.; van Lookeren Campagne, M.; Wiesmann, C.
Addition of bevacizumab to fluorouracil-based first-line treatment of metastatic colorectal cancer: pooled analysis of cohorts of older patients from two randomized clinical trials
Journal of Clinical Oncology, 2009, ISSN: 0732-183X
Kabbinavar, F.F.; Hurwitz, H.I.; Yi, J.; Sarkar, S.; Rosen, O.
Distinct thresholds govern Myc's biological output In Vivo
Cancer Cell, 2008, ISSN: 1535-6108
Murphy, D.J.; Junttila, M.R.; Pouyet, L.; Karnezis, A.; Shchors, K.; Bui, D.A.; Brown-Swigart, L.; Johnson, Leisa.; Evan, G.I.
Trace level analysis of leached Protein A in bioprocess samples without interference from the large excess of rhMAb IgG
Journal of Immunological Methods, 2009, ISSN: 0022-1759
Zhu-Shimoni, J.; Gunawan, F.; Thomas, A.; Vanderlaan M.; Stults, J.
Crystal structure of procaspase-1 zymogen domain reveals insight into inflammatory caspase autoactivation.
Journal of Biological Chemistry, 2009, ISSN: 0021-9258
Elliott, J.M.; Rouge, L.; Wiesmann, C.; Scheer, J.M.
Automated de novo sequencing of monoclonal antibodies
Nature Biotechnology, 2008, ISSN: 1087-0156