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Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 1 - 50 OF 12441 RESULTS

Practical Early Development Synthesis of Nav17 Inhibitor GDC-0310
Synthesis (Germany), ISSN: 00397881
Andy Stumpf; Frederic St-Jean; David Lao; Zhiyong (Jay) Cheng; Remy Angelaud; Francis Gosselin
Using differential scanning calorimetry for the development of non-reduced capillary electrophoresis sodium dodecyl sulfate methods for monoclonal antibodies
Analytical Biochemistry, ISSN: 00032697
Patricia Molina; Arthur J. Schick; Leslie Welch; Thomas Niedringhaus; Gabriella del Hierro; Galahad Deperalta; Aaron Hieb
Improving Prediction of Free Fatty Acid Particle Formation in Biopharmaceutical Drug Products: Incorporating Ester Distribution during Polysorbate 20 Degradation
Molecular Pharmaceutics,
Nidhi Doshi; Joelle Martin; Anthony Tomlinson
Eye, ISSN: 14765454 0950222X
Anthony Adamis; Christopher Brittain; Atul Dandekar; Jill Hopkins
Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti-Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
Drug Metabolism and Disposition,
Hao Cai; Victor Yip; Violet Lee; Sylvia Wong; Ola Saad; Shuguang Ma; Nina Ljumanovic; S Cyrus Khojasteh; Amrita Kamath; Ben-Quan Shen
Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
Frances Humby; Myles J. Lewis; Michael Townsend; Costantino Pitzalis
AAPS Journal, ISSN: 15507416
Arian Emami Riedmaier; Kevin DeMent; James Huckle; Phil Bransford; Cordula Stillhart; Richard Lloyd; Ravindra Alluri; Sumit Basu; Yuan Chen; Varsha Dhamankar; Stephanie Dodd; Priyanka Kulkarni; Andrés Olivares-Morales; Chi-Chi Peng; Xavier Pepin; Xiaojun Ren; Thuy Tran; Christophe Tistaert; Tycho Heimbach; Filippos Kesisoglou; Christian Wagner; Neil Parrott
Impact of Silicone Oil on Free Fatty Acid Particle Formation due to Polysorbate 20 Degradation
Pharmaceutical Research, ISSN: 07248741
Raphael Fish; Jasper Lin; Nidhi Doshi
Water related impact of energy: Cost and carbon footprint analysis of water for biopharmaceuticals from tap to waste
Chemical Engineering Science: X,
Alessandro Luigi Cataldo; Bernhard Sissolak; Karl Metzger; Kristi Budzinski; Osamu Shirokizawa; Markus Luchner; Alois Jungbauer; Peter Satzer
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Keira Garland; Homer Pantua; Marie-Gabrielle Braun; Dan Burdick; Georgette Castanedo; Yi-Chen Chen; Yun-Xing Cheng; Jonathan Cheong; Blake Daniels; Gauri Deshmukh; Yuhong Fu; Paul Gibbons; Susan Gloor; Rongbao Hua; Sharada Labadie; Xiongcai Liu; Rich Pastor; Craig Stivala; Min Xu; Yiming Xu; Hao Zheng; Sharookh Kapadia; Emily Hanan
Inter-individual and inter-regional variations in enteric drug metabolizing enzyme activities: Results with cryopreserved human intestinal mucosal epithelia (CHIM) from the small intestines of 14 donors
Pharmacology Research and Perspectives,
Albert P. Li; Ming-Chih D Ho; Novera Alam; Walter Mitchell; Susan Wong; Zhengyin Yan; Jane Kenny; Cornelis E C A Hop
Autoimmunity linked protein phosphatase PTPN22 as a target for cancer immunotherapy
Journal for ImmunoTherapy of Cancer,
Rafael Cubas; Zia Khan; Qian Gong; Marina Moskalenko; Huizhong Xiong; Qinglin Ou; Christine Pai; Ryan Rodriguez; Jeanne Cheung; Andrew A. Chan
Bioanalysis, ISSN: 17576199 17576180
Gizette Sperinde; Meire Bremer; Henry Maun; Amos Baruch; Bob Lazarus; JT Koerber; Rajesh Vij; Tangsheng Yi; Sally Fischer; Tracy Staton
Bioanalysis, ISSN: 17576199
Sally Fischer; Kathi Williams; Ian Harmon; Bryan Bothwell; Hua Xu; Emmanuel Capio; Mikhail Briman
Pulmonary Pharmacology and Therapeutics, ISSN: 15229629 10945539
John Busby; Cecile Holweg; Akiko Chai; Peter Bradding; Rekha Chaudhuri; Adel Mansur; John Matthews; Andrew Menzies-Gow; James Lordan; Robert Niven; Liam G. Heaney
Atezolizumab for first-line treatment of PD-L1–selected patients with NSCLC
New England Journal of Medicine, ISSN: 00284793
Roy S. Herbst; Giuseppe Giaccone; Filippo De Marinis; Niels Reinmuth; Alain Vergnenegre; Carlos H. Barrios; Masahiro Morise; Enriqueta Felip; Zoran Andric; Sarayut Geater; Mustafa Özgüroğlu; Wei Zou; Alan Sandler; Ida Enquist; Kimberly Komatsubara; Deng; Hiroshi Kuriki; Wen; Mark McCleland; Simonetta Mocci; Jacek Jassem; David Spigel
Single-cell transcriptome profiling of the kidney glomerulus identifies key cell types and reactions to injury
Journal of the American Society of Nephrology, ISSN: 10466673
Jun-Jae Chung; Leonard Goldstein; Jasmine Chen; Jiyeon Lee; Webster; Meron Roose-Girma; Sharad C. Paudyal; Zora Modrusan; Anwesha Dey; Andrey Shaw
JCI insight, ISSN: 23793708
Kasia Owczarczyk; Matthew Cascino; Cecile Holweg; Wei Tew; Ward Ortmann; Timothy Behrens; Thomas Schindler; Langford; E. William St. Clair; Merkel; Spiera; Seo; Cees Gm Kallenberg; Specks; Noha Lim; John H. Stone; Paul Brunetta; Marco Prunotto
Conjugation Site Influences Antibody-Conjugated Drug PK Assays: Case Studies for Disulfide-Linked, Self-Immolating Next-Generation Antibody Drug Conjugates
Analytical Chemistry, ISSN: 00032700
Violet Lee; Surinder Kaur; Ola Saad
Systematic Variation of Pyrrolobenzodiazepine (PBD)-Dimer Payload Physicochemical Properties Impacts Efficacy and Tolerability of the Corresponding Antibody-Drug Conjugates
Journal of Medicinal Chemistry,
Leanna Staben; Jinhua Chen; Josefa Dela Cruz-Chuh; Geoff Del Rosario; Mary Ann Go; Jun Guo; S Cyrus Khojasteh; Kathy Kozak; Ginny Li; Carl Ng; Gail D. Lewis Phillips; Thomas Pillow; Rebecca K. Rowntree; John Wai; Binqing Wei; Keyang Xu; Zijin Xu; Shang-Fan Yu; Donglu Zhang; Peter Dragovich
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Bingchuan Wei; Weitao Jia; Yi Yang; Mansour Jazayri; David Fulchiron; Justin Jeong; Qian Cai; Charlene Li; John Briggs; Milady Ninonuevo; Hongbin Liu; Zane Liu; Yonghua Taylor Zhang
Ectoine and Hydroxyectoine Stabilize Antibodies in Spray-Dried Formulations at Elevated Temperature and during a Freeze/Thaw Process
Molecular Pharmaceutics,
Purnendu K. Nayak; Meghan Goode; Debby Chang; Karthik Rajagopal
Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPβ in Microglia
Cell, ISSN: 00928674
Ada Ndoja; Rohit Reja; Seung-Hye Lee; Webster; Hai Ngu; Christopher M. Rose; Don Kirkpatrick; Zora Modrusan; Ying-Jiun Jasmine Chen; Debbie Dugger; Vineela Gandham; Luke Xie; Kim Newton; Vishva Dixit
Journal of the American Society of Nephrology, ISSN: 15333450 10466673
Suzie Scales; Nidhi Gupta; Ann De Mazière; George Posthuma; Cecilia P. Chiu; Andrew A. Pierce; Kathy Hotzel; Jianhua Tao; Oded Foreman; Georgios Koukos; Francesca Oltrabella; Judith Klumperman; WeiYu Lin; Andy Peterson
Journal of the American Society of Nephrology, ISSN: 15333450 10466673
Nidhi Gupta; Grace Wang; Xiaohui Wen; Paul Moran; Maciej Paluch; Phil Hass; Amy Heidersbach; Benjamin Haley; Daniel Kirchhofer; Randall Brezski; Andy Peterson; Suzie Scales
Haematologica, ISSN: 15928721 03906078
Chris Bolen; Magdalena Klanova; Marek Trneny; Laurie H. Sehn; Jie He; Jing Tong; Joseph N. Paulson; Eugene Kim; Umberto Vitolo; Alice Di Rocco; Guenter Fingerle-Rowson; Tina Nielsen; Lenz; Mikkel Z. Oestergaard
Suppressing neutrophil-dependent angiogenesis abrogates resistance to anti-VEGF antibody in a genetic model of colorectal cancer
Proceedings of the National Academy of Sciences of the United States of America,
Yoshiro Itatani; Takamasa Yamamoto; Cuiling Zhong; Alfredo A. Molinolo; Jane Ruppel; Priti Hegde; M Mark Taketo; Napoleone Ferrara
Unstable mechanisms of resistance to inhibitors of escherichia coli lipoprotein signal peptidase
mBio, ISSN: 21612129
Homer Pantua; Elizabeth Skippington; Marie-Gabrielle Braun; Cameron Noland; Jingyu Diao; Yutian Peng; Susan Gloor; Donghong Yan; Jing Kang; Anand Kumar Katakam; Janina Reeder; Georgette Castanedo; Keira Garland; László Kömüves; Meredith Sagolla; Cary Austin; Jeremy Murray; Yiming Xu; Zora Modrusan; Min Xu; Emily Hanan; Sharookh Kapadia
A Physiologically Based Pharmacokinetic Model of Vismodegib: Deconvoluting the Impact of Saturable Plasma Protein Binding, pH-Dependent Solubility and Nonsink Permeation
AAPS Journal,
Michael J. Dolton; Po-Chang Chiang; Fang Ma; Jin Y. Jin; Yuan Chen
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Teresa Mulder; Sudheer Bobba; Kevin Johnson; Jessica M. Grandner; Wei Wang; Chenghong Zhang; Jingwei Cai; Edna F. Choo; Cyrus Khojasteh; Donglu Zhang
Fenebrutinib Versus Placebo or Adalimumab in Rheumatoid Arthritis: A Randomized, Double-Blind, Phase II Trial
Arthritis and Rheumatology, ISSN: 23265191
Stanley B. Cohen; Katie Tuckwell; Tamiko R. Katsumoto; Rui Zhao; Joshua Galanter; Chin H. Lee; Julie Rae; Balazs Toth; Nandhini Ramamoorthi; Jason Hackney; Alberto Berman; Nemanja Damjanov; Dmytro Fedkov; Slawomir Jeka; Leslie Chinn; Michael Townsend; Alyssa M. Morimoto; Mark C. Genovese
PDA Journal of Pharmaceutical Science and Technology, ISSN: 19482124
Wen-Li Chung; Jian Yin; Steven Messick; Miguel Saggu; Kate Tschudi; Ann Marie Woys; Rod Rahimi; Marianne Azarias; Connie Kong; Bruce Kabakoff
Analytical Chemistry, ISSN: 15206882 00032700
Delia Li; Adam Farchone; Qing Zhu; Frank Macchi; Donald Walker; David Michels; Feng Yang
Biochemical Society Transactions, ISSN: 14708752
Daniel Kirchhofer; Dan Burdick; Nicholas Skelton; Yingnan Zhang; Mark Ultsch
Journal of Biotechnology, ISSN: 18734863 01681656
Salina Louie; Jayanthi Lakkyreddy; Brian M. Castellano; Benjamin Haley; Anh Nguyen Dang; Cynthia Lam; Danming Tang; Steven E. Lang; Brad Snedecor; Shahram Misaghi