Medical Professionals / Our Medicines & Products

Medicines and Products

Prescribing Information

Medication Guide

Healthcare Provider Letter

Safety Data Sheets

Alecensa® (alectinib)

Healthcare Provider Letters:

Important Drug Warning - December 2021

Safety Data Sheets:

ALECENSA Capsules 150 mg

Avastin® (bevacizumab)

Healthcare Provider Letters:

Important Drug Warning - August 2024 Important Drug Warning: Necrotizing Fasciitis - Apr 2013 Warning for Counterfeit Product Labeled as Avastin in the United States Feb 2012 Important Change to Avastin® label for treatment of metastatic breast cancer - Nov 2011 Important New Safety Information in Women Receiving AVASTIN - Oct 2011 Intraocular Inflammatory Reactions - Dec 2008 Microangiopathic Hemolytic Anemia (MAHA) - July 2008 Tracheoesophageal (TE) Fistula - April 2007 Cases of RPLS in Patients Receiving AVASTIN - Sept 2006 VEGF antibodies for the treatment of retinopathy of prematurity - Aug 2006

Safety Data Sheets:

AVASTIN Vials 100 mg/4 ml AVASTIN Vials 400 mg/16 ml

Columvi® (glofitamab-gxbm)

Healthcare Provider Letters:

Important Drug Warning - January 2026

Safety Data Sheets:

COLUMVI Vials 2.5 mg/2.5ml COLUMVI Vials 10 mg/10ml

Cotellic® (cobimetinib)

Safety Data Sheets:

COTELLIC Tablets 20 mg

Erivedge® (vismodegib)

Healthcare Provider Letters:

Important Drug Warning - November 2016 Serious Risk with Use of Erivedge (vismodegib) Capsules: Premature Epiphyseal Fusion - June 2016 Extension of Pregnancy Prevention Duration for Women of Childbearing Potential and Waiting Periods for Blood Donations and Lactation in Patients taking ERIVEDGE (vismodegib) capsule - February 2016

Safety Data Sheets:

ERIVEDGE Capsules 150 mg

Gazyva® (obinutuzumab)

Healthcare Provider Letters:

Gazyva TM (obinutuzumab) Important Drug Warning: Thrombocytopenia - Feb 2014

Safety Data Sheets:

GAZYVA Vials 1000 mg/40ml

Herceptin® (trastuzumab)

Healthcare Provider Letters:

440mg Vials and Herceptin BWFI Diluent - June 2008 Updated Cardiotoxicity Information - Aug 2005 Fatal Embryo-Fetal Toxicity due to Herceptin Exposure During Pregnancy

Safety Data Sheets:

HERCEPTIN Vials 150 mg

Herceptin Hylecta™ (trastuzumab and hyaluronidase-oysk)

Safety Data Sheets:

HERCEPTIN HYLECTA Vials 600 mg/5 ml

Itovebi™ (inavolisib)

Healthcare Provider Letters:

Important Drug Warning - March 2025

Safety Data Sheets:

ITOVEBI Tablets 3 mg ITOVEBI Tablets 9 mg

Kadcyla® (ado-trastuzumab emtansine)

Healthcare Provider Letters:

Kadcyla Important Safety Warning: Hemorrhage, Nov 2013 KADCYLA (ado-trastuzumab emtansine) error on the carton - May 2013

Safety Data Sheets:

KADCYLA 2% aqueous solution KADCYLA Vials 160 mg KADCYLA Vials 100 mg KADCYLA(R) Lyophilized Powder in Vials (100 mg) KADCYLA(R) Lyophilized Powder in Vials (160 mg) KADCYLA(R) Solution

Lunsumio® (mosunetuzumab-axgb)

Safety Data Sheets:

LUNSUMIO Vials 30 mg/30 ml LUNSUMIO Vials 1 mg/1 ml

Lunsumio Velo™ (mosunetuzumab-axgb)

Perjeta® (pertuzumab)

Safety Data Sheets:

PERJETA Vials 420 mg/14 ml

Phesgo® (pertuzumab, trastuzumab, and hyaluronidase-zzxf)

Safety Data Sheets:

PHESGO Vials 600/600mg/10ml PHESGO Vials 1200/600mg/15ml PHESGO™ (pertuzumab, trastuzumab & hyaluronidase-zzxf) Injection (60 mg/ml, 60 mg/ml) PHESGO™ (pertuzumab, trastuzumab & hyaluronidase-zzxf) Injection (80 mg/ml, 40 mg/ml)

Polivy® (polatuzumab vedotin-piiq)

Healthcare Provider Letters:

Important Drug Warning - September 2025

Safety Data Sheets:

POLIVY Vials 140 mg POLIVY Vials 30 mg

Rituxan® (rituximab [Oncology])

Healthcare Provider Letters:

Rituxan® (rituximab) Label: Hepatitis B Reactivation, October 2013 Important Drug Warning: Updated Safety Information - Dec 2006 Important Drug Warning: New Safety Information - Sept 2008 Important Drug Warning: Updated Safety Information - Oct 2009

Safety Data Sheets:

RITUXAN Vials 100 mg/10 ml RITUXAN Vials 500 mg/50 ml

Rituxan Hycela® (rituximab and hyaluronidase human)

Safety Data Sheets:

RITUXAN HYCELA (TM) Vials 1600 mg/13.4 ml RITUXAN HYCELA (TM) Vials 1400 mg/11.7 ml

Rozlytrek® (entrectinib)

Safety Data Sheets:

ROZLYTREK(TM) Capsules 100 mg ROZLYTREK(TM) Capsules 200 mg ROZLYTREK(R) Oral Pellets 50 mg

Tecentriq® (atezolizumab)

Healthcare Provider Letters:

Important Drug Warning - August 2024 Important Prescribing Information - November 2022 Important Prescribing Information - August 2021 Important Prescribing Information - May 2021 Important Prescribing Information - March 2021 Follow Up Important Prescribing Information - March 2021 Important Drug Warning - August 2018 Important Prescribing Information - June 2018 Important Drug Warning - July 2017

Safety Data Sheets:

TECENTRIQ® Vials 840 mg/14 ml TECENTRIQ® Vials 1200 mg/20 ml

Tecentriq Hybreza™ (atezolizumab and hyaluronidase-tqjs)

Safety Data Sheets:

TECENTRIQ HYBREZA™ Vials 1875 mg/15 ml

Venclexta® (venetoclax)

Safety Data Sheets:

VENCLEXTA(R) Tablets (10, 50 and 100 mg)

Zelboraf® (vemurafenib)

Healthcare Provider Letters:

Important Drug Warning - June 2017 Important Drug Warning - March 2014 Important Drug Warning - August 2013

Safety Data Sheets:

ZELBORAF(R) Tablets 240 mg

Actemra® (tocilizumab)

Healthcare Provider Letters:

Important Drug Warning - November 2024 Important Prescribing Information - Temporary Supply Shortage Actemra 20 mg/mL Concentrate for Solution for Infusion (IV) September 2021 Apr 2020 - Shipping short-dated Actemra (tocilizumab) 400 mg/20 mL vial for IV with dark blue cap Important Drug Warning - 2019 IMPORTANT SAFETY INFORMATION Regarding ACTEMRA® (tocilizumab) REMS, October 2013 Actemra for RA and SJIA - June 2011 Actemra for RA and SJIA - Oct 2012

Safety Data Sheets:

ACTEMRA SC Autoinjector 162 mg/0.9 ml ACTEMRA Vials 80 mg/4ml ACTEMRA SC Prefilled Syringes 162 mg/0.9 ml ACTEMRA Vials 200 mg/10 ml ACTEMRA Vials 400 mg/20 ml

Esbriet® (pirfenidone)

Healthcare Provider Letters:

Important Drug Warning - August 2019

Safety Data Sheets:

ESBRIET Tablets 267 mg ESBRIET Tablets 801 mg ESBRIET Capsules 267 mg

Lucentis® (ranibizumab injection)

Healthcare Provider Letters:

New Warnings and Precautions: Retinal Vasculitis with or without Occlusion – March 2024 Counterfeit Product - November 2018 Important Drug Notification: Intraocular Inﬂammatory Reactions After Intravitreal Injection - Dec 2008 SAILOR with AMD - Jan 2007 Safety Risk with Intravitreal Use of VEGF - Aug 2006

Safety Data Sheets:

LUCENTIS PFS 0.5 mg/0.05ml LUCENTIS PFS 0.3 mg/0.05 ml

Rituxan® (rituximab [Immunology])

Healthcare Provider Letters:

Rituxan® (rituximab) Label: Hepatitis B Reactivation, October 2013 Rituxan and PML - Oct 2009 Rituxan and RA - Sept 2008 Rituxan and the treatment of SLE - Dec 2006

Safety Data Sheets:

RITUXAN Vials 100 mg/10 ml RITUXAN Vials 500 mg/50 ml

Susvimo® (ranibizumab injection)

Healthcare Provider Letters:

Important Drug Warning - October 2025 Important Prescribing Information - March 2025

Safety Data Sheets:

SUSVIMO Vials 10 mg/0.1 ml

Vabysmo® (faricimab-svoa)

Healthcare Provider Letters:

Important Drug Warning – November 2023

Safety Data Sheets:

VABYSMO Vials/PFS 6 mg/0.05 ml

Xolair® (omalizumab)

Healthcare Provider Letters:

June 2021 - Important Prescribing Information April 2020 - Important Prescribing Information: Self-administration during the COVID-19 pandemic

Safety Data Sheets:

XOLAIR(R) PFS 150mg/ml XOLAIR(R) PFS 75mg/0.5ml XOLAIR(R) Vials (150 mg) XOLAIR(R) PFS 300mg/2ml

Nutropin AQ® ((somatropin) injection for subcutaneous use)

Safety Data Sheets:

NUTROPIN Cartridges 5 mg/2ml NUTROPIN Cartridges 10 mg/2ml NUTROPIN Cartridges 20 mg/2ml

Activase® (alteplase)

Healthcare Provider Letters:

Important Prescribing Information - November 2024 Stopper Dislodgement - How to reduce the risk of stopper dislodgement and leakage when using 100-mg vials

Safety Data Sheets:

ACTIVASE Vials 50 mg ACTIVASE Vials 100 mg

Enspryng® (satralizumab-mwge)

Safety Data Sheets:

ENSPRYNG SC PFS 120 mg/ml

Evrysdi® (risdiplam)

Healthcare Provider Letters:

Information Regarding Potential Leakage of Evrysdi (risdiplam) 0.75 mg/mL NDC 50242-175-07 Solution from Bottles Delivered to Patients

Safety Data Sheets:

EVRYSDI Powder for Oral Solution 60 mg EVRYSDI (Risdiplam) 0.75 mg/ml

Ocrevus® (ocrelizumab)

Healthcare Provider Letters:

Important Drug Warning - August 2025

Safety Data Sheets:

OCREVUS Vials 300 mg/10ml

Ocrevus Zunovo® (ocrelizumab and hyaluronidase-ocsq)

Healthcare Provider Letters:

Important Drug Warning - August 2025

Safety Data Sheets:

OCREVUS ZUNOVO Vials 920 mg/23 ml

CellCept® (mycophenolate mofetil)

Healthcare Provider Letters:

Important Drug Warning - September 2025 Correction of labeling provided with CellCept® Intravenous and CellCept® Oral Suspension - May 2015 Important Changes in the CellCept® Prescribing Information - June 2008 Mycophenolate REMS (Risk Evaluation and Mitigation Strategy) - 2012 Reports of Pure Red Cell Aplasia - Aug 2009 Pregnancy Notice - 2010 Pharmacists: Important New Dispensing Information - Jan 2009 Introduction of a CellCept Medication Guide - Jan 2009 Important Changes in the CellCept® Prescribing Information - Oct 2007

Safety Data Sheets:

CELLCEPT Capsules 250 mg CELLCEPT Tablets 500 mg CELLCEPT Oral Suspension 200 mg/ml CELLCEPT Vials 500 mg CELLCEPT Powder for suspension 200 mg/ml

Pulmozyme® (dornase alfa)

Safety Data Sheets:

PULMOZYME Ampoules 2,5 mg/2,5ml Pulmozyme(R) Inhalation Solution (2.5 mg)

Tamiflu® (oseltamivir phosphate)

Healthcare Provider Letters:

Tamiflu Dear Pharmacist Letter Removal of Dosing Dispenser-Aug 2013 Important Prescribing Information for Patients Under 1 - Jan 2013

Safety Data Sheets:

TAMIFLU(R) Capsules 30 mg TAMIFLU(R) Capsules 45 mg TAMIFLU(R) Capsules 75 mg TAMIFLU(R) Powder for Susp. 30 mg/5ml TAMIFLU(R) Suspension 6 mg/ml

Xofluza® (baloxavir marboxil)

Healthcare Provider Letters:

Important Prescribing Information - October 2019

Safety Data Sheets:

XOFLUZA(TM) Granules for Oral Susp. 2 mg/ml XOFLUZA(TM) Reconst. Oral Susp. 2 mg/ml XOFLUZA(TM) Tablets 40 mg XOFLUZA(TM) Tablets 80 mg

Cathflo Activase® (alteplase)

Healthcare Provider Letters:

Important Drug Warning - May 2024 Important Drug Information: New rubber stoppers now available - Dec 2014 Important Drug Information: Filtering Instructions for Pharmacists - Mar 2013

Safety Data Sheets:

CATHFLO ACTIVASE Vials 2mg

Floodlight™ (MS)

Hemlibra® (emicizumab-kxwh)

Safety Data Sheets:

HEMLIBRA Vials 30 mg/1 ml HEMLIBRA Vials 60 mg/0.4ml HEMLIBRA Vials 105 mg/0.7ml HEMLIBRA Vials 150 mg/ml HEMLIBRA Vials 12mg/0.4ml HEMLIBRA Vials 300 mg/2ml

PiaSky® (crovalimab-akkz)

Safety Data Sheets:

PIASKY Vials 340 mg/2 ml

TNKase® (tenecteplase)

Healthcare Provider Letters:

Recall of Triad Group Alcohol Prep Products Due to Potential Microbial Contamination - Jan 2011

Safety Data Sheets:

TNKASE(R) Vials 50 mg

Access to Investigational Medicines
We're committed to a fair and impartial evaluation of each request for access to our investigational medicines.
Genentech iMedConnect
Scientific and clinical information for U.S. Healthcare Providers.
Find Open Clinical Trials
Search clinicaltrials.gov to find out if a trial exists for a specific medicine for a particular disease.

Attention: This page may not render properly. The browser you are using, Internet Explorer 10, is no longer supported.

Medicines and Products

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Safety Data Sheets:

Safety Data Sheets:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Safety Data Sheets:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Safety Data Sheets:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

Safety Data Sheets:

Safety Data Sheets:

Healthcare Provider Letters:

Safety Data Sheets:

You Might Also Be Interested In