Andy Boswell - Senior Scientist, Preclinical and Translational Pharmacokinetics, Development Sciences

Andy Boswell

Senior Scientist, Preclinical and Translational Pharmacokinetics, Development Sciences

Postdoc Mentor
"I am driven by the opportunity to apply a multidisciplinary approach to drug development in an effort to improve patients’ lives."
10
Years at Genentech
27
Publications
5
Awards & Honors

Since joining Genentech in 2007, I have been responsible for understanding the absorption, metabolism, distribution and excretion of many of our large molecule therapeutics to help ensure that we achieve adequate drug exposure in the appropriate tissue compartments. In the Investigative Pharmacokinetics group, we apply a multidisciplinary approach to characterize the biodistribution of antibodies, including radiochemical, biochemical and molecular imaging techniques. Our group provides support across all therapeutic areas, including neuroscience and ophthalmology for which there are unique challenges in drug delivery and development. In my lab, we strive to provide guidance in designing and selecting the best molecule as well as the appropriate dose and regimen to achieve the pharmacologic exposure needed for efficacy.

Post Doctoral Mentor

My research vision is focused at the interface of chemistry and biology, with particular interest in using radiochemical probes to aid in the design, delivery and development of large molecule therapeutics. I feel extremely fortunate to work in a biotech company with amazing scientific resources and with the ability to participate in a postdoctoral mentoring program. The ability to tackle scientific questions that arise in drug development presents a unique opportunity for a successful postdoctoral research project.

Featured Publication

Enhanced tumor retention of a radiohalogen label for site-specific modification of antibodies.

J Med Chem. 2013 Dec 12;56(23):9418-26.

Boswell CA, Marik J, Elowson MJ, Reyes NA, Ulufatu S, Bumbaca D, Yip V, Mundo EE, Majidy N, Van Hoy M, Goriparthi SN, Trias A, Gill HS, Williams SP, Junutula JR, Fielder PJ, Khawli LA.