"It’s a privilege to be able to work on problems both intellectually challenging and societally significant."
I joined Genentech in August 2021, when Prescient Design was acquired and incorporated into gRED. My postdoctoral work had been predominantly in RNA structure prediction, and my doctoral work on peptidomimetic design, so I was delighted to start work on biologics, a fairly new topic.
I’ve got a lot to learn!
I think an industry postdoc presents a unique opportunity not available in traditional academic positions: the combination of top-level academic mentorship with a highly resourced environment. It also presents a valuable opportunity to groups like ours: through postdocs, we can pursue basic science projects with significant academic value whose success may accelerate our core projects.
2021 Aug 27;373(6558):1047-1051.
I lead a team of scientists whose focus is biomolecular structure prediction and design. In particular, we complement the sequence-driven design methods from Prescient’s machine learning team: we can fold those sequences, predict their biophysical properties, and use those predictions to filter poor candidates. (Prospectively, we can then learn sequence-level filters to accelerate the design macrocycle further.)