Ciara Metcalfe - Senior Principal Scientist, Translational Oncology, Research Biology

Ciara Metcalfe

Senior Principal Scientist, Translational Oncology, Research Biology

Postdoc Mentor
"Cells are truly amazing, profoundly elegant biological machines – it is such a privilege and a joy to be enabled to tackle the biological mysteries that are most meaningful to human health."
Years at Genentech
Publications at Genentech
Awards & Honors

I began my scientific training at the University of the Witwatersrand in Johannesburg, South Africa, followed by graduate research at the MRC Laboratory of Molecular Biology at the University of Cambridge, UK. I came to Genentech as a Postdoctoral Fellow in 2010, and then gained valuable experience as a Scientist in Genentech’s Oncology Biomarker Department. I joined the Translational Oncology department to lead my own research group in 2015.

I was drawn to Genentech because of its reputation for top-class, creative and innovative science. I choose to stay because of the unique opportunity that Genentech provides to turn that top-class science into transformational medicines for patients.

Postdoctoral Mentor

I loved and deeply value my time as Postdoctoral Fellow at Genentech – I learned a tremendous amount as part of an energized, engaged, and high functioning community. I am really looking forward to providing that same opportunity to trainee scientists who are inspired to make new discoveries around meaningful biological questions.

Featured Publication

Lgr5+ stem cells are indispensable for radiation-induced intestinal regeneration.

Cell Stem Cell. 2014 Feb 6;14(2):149-59.

Metcalfe C, Kljavin NM, Ybarra R, de Sauvage FJ.