I started at Genentech in 1999 in what was then the Bioorganic Chemistry Department. I was attracted to Genentech based primarily on the people that were here, their enthusiasm for science, and the opportunity to work closely with world-class biologists. Since that time I have enjoyed the experience of working in many therapeutic areas (cardiovascular, oncology, immunology, and neuroscience) and on many different target classes including kinases, proteases, integrins, and ion-channels. In each project there have always been new and interesting challenges to overcome that has kept me curious about and engaged in the science of drug discovery.
J. Med. Chem. 2011, 54:7579.
I am currently the research and development project leader of a new and exciting Pain target. Mutations in this ion channel have profound effects on pain.
The chance to participate in such an exciting area of science while being focused on a serious unmet medical need has been motivating.