Donglu Zhang - Senior Fellow, Drug Metabolism and Pharmacokinetics, Drug Discovery

Donglu Zhang

Senior Fellow, Drug Metabolism and Pharmacokinetics, Drug Discovery

Fellow
"Innovation and collaboration drive pharmaceutical breakthroughs."
10
Years at Genentech
2
Awards & Honors

It is a privilege to work at Genentech with highly motivated and talented scientists who transform science, medicine, and society through innovation and deep commitment to patients.

Featured Publication

Industry Perspective on the Pharmacokinetic and ADME Characterization of Heterobifunctional Protein Degraders.

Drug Metab Dispos.

Zhang et al., (2023)

Design and Measurement of Drug Tissue Concentration Asymmetry and Tissue Exposure-Effect (Tissue PK-PD) Evaluation.

J Med Chem.

Zhang et al., (2022)

Intestinal excretion, enteroenteric recirculation and renal tubule recirculation are a under-appreciated pharmacokinetic driver for small molecule drugs.

J Med Chem.

Zhang et al., (2021)

Intestinal Excretion, Intestinal Recirculation, and Renal Tubule Reabsorption Are Underappreciated Mechanisms That Drive the Distribution and Pharmacokinetic Behavior of Small Molecule Drugs.

J Med Chem.

Zhang et al., (2021)

Linker Design Impacts Antibody-Drug Conjugate Pharmacokinetics and Efficacy via Modulating the Stability and Payload Release Efficiency.

Front Pharmacol.

Zhang, d.; Su, d. (2021)

Exposure-effect analysis of antibody-drug conjugates delivering an excess level of payload to tumors.

Drug Metab Dispos, 47:1146.

Zhang et al., (2019)

Tissue concentration asymmetry for novel therapeutic modalities.

Drug Metab Dispos, 47:1122.

Zhang et al., (2019)