Donglu Zhang
Senior Fellow, Drug Metabolism & Pharmacokinetics, Drug Discovery
Fellow
"Innovation and collaboration drive pharmaceutical breakthroughs."
10
Years at Genentech
2
Awards & Honors
It is a privilege to work at Genentech with highly motivated and talented scientists who transform science, medicine, and society through innovation and deep commitment to patients.
Featured Publication
Industry Perspective on the Pharmacokinetic and ADME Characterization of Heterobifunctional Protein Degraders.
Drug Metab Dispos.
Design and Measurement of Drug Tissue Concentration Asymmetry and Tissue Exposure-Effect (Tissue PK-PD) Evaluation.
J Med Chem.
Intestinal excretion, enteroenteric recirculation and renal tubule recirculation are a under-appreciated pharmacokinetic driver for small molecule drugs.
J Med Chem.
Intestinal Excretion, Intestinal Recirculation, and Renal Tubule Reabsorption Are Underappreciated Mechanisms That Drive the Distribution and Pharmacokinetic Behavior of Small Molecule Drugs.
J Med Chem.
Linker Design Impacts Antibody-Drug Conjugate Pharmacokinetics and Efficacy via Modulating the Stability and Payload Release Efficiency.
Front Pharmacol.
Exposure-effect analysis of antibody-drug conjugates delivering an excess level of payload to tumors.
Drug Metab Dispos, 47:1146.
Tissue concentration asymmetry for novel therapeutic modalities.
Drug Metab Dispos, 47:1122.