"My inspiration comes from the enthusiasm and dedication of my team and collaborators. I am extremely proud to be part of this rewarding endeavor and excited to see our current early stage drug discovery research & technology development projects come to fruition."
I decided to pursue a career at Genentech as it presented the opportunity to join a world-leading research environment.
As the leader of the Proteomics and Biological Resources department, I am involved in many projects encompassing a variety of disciplines and cutting-edge drug discovery research topics. In addition to these collaborations, I also have the opportunity to initiate novel biochemical and mass spectrometric technology development projects.
Science. 2012 Sep 21;337(6101):1541-6. Epub 2012 Aug 9.
My main role is to direct the activities of the Proteomics & Biological Resource Department at Genentech. On the research side within my own sub-lab our current technological development projects include novel PTM site mapping protocols, methods for the identification of proteolysis substrates related to various disease states, chemo-proteomic workflows and the development of bioinformatic tools too allow us to stream line our data analysis & presentation. We are also involved with developing methods using the PTMscan technology licensed from Cell Signaling Technologies to unravel low level signaling pathways to aid in understand cellular signaling events in addition to crafting our own workflows and novel in house designed reagents to give us a competitive advantage in proteome related drug discovery efforts.