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Joachim Rudolph - Senior Principal Scientist, Discovery Chemistry

Joachim Rudolph

Senior Principal Scientist, Discovery Chemistry

Postdoc Mentor
14
Years at Genentech
34
Publications
7
Awards & Honors

I joined Genentech in 2007 with 10 years of prior industry experience in the US and Germany.

I did my doctoral studies in organic chemistry at the Max-Planck Institute in Mülheim, Germany, in the group of Manfred Reetz, followed by a post-doctoral stay at The Scripps Research Institute in the laboratory of K. Barry Sharpless. My pharmaceutical industry career began in 1997 at Bayer in Germany and continued in the Bayer Pharmaceutical Research Center in West Haven, Connecticut until 2007.

At Genentech, I have been a chemistry team leader and project leader for multiple small-molecule discovery programs, with a focus in the area of oncology and a growing involvement in early discovery programs and new modalities.

Postdoctoral Mentor

I enjoy working with young scientists with an interest in interdisciplinary research and a drive to venture into the unknown. Genentech offers endless opportunities for collaboration and a fantastic environment to make important discoveries happen.

Featured Publication

Emerging Trends in Cancer Drug Discovery—From Drugging the “Undruggable” to Overcoming Resistance

Cancer Discov 2021, 11 (4), 815–821

Rudolph, J.; Settleman, J.; Malek, S.

Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5-Fluoro-4-(3H)-quinazolinone Aryl Urea pan-RAF Kinase Inhibitor

J Med Chem 2021, 64 (7), 3940–3955.

Huestis, M. P.; Cruz, D. D.; DiPasquale, A. G.; Durk, M. R.; Eigenbrot, C.; Gibbons, P.; Gobbi, A.; Hunsaker, T. L.; La, H.; Leung, D. H.; Liu, W.; Malek, S.; Merchant, M.; Moffat, J. G.; Muli, C. S.; Orr, C. J.; Parr, B. T.; Shanahan, F.; Sneeringer, C. J.; Wang, W.; Yen, I.; Yin, J.; Siu, M.; Rudolph, J.