Nicholas Agard - Senior Principal Scientist, Antibody Engineering

Nicholas Agard

Senior Principal Scientist, Antibody Engineering

Postdoc Mentor
Years at Genentech
Publications at Genentech
Awards & Honors

I joined Genentech as a Scientist in 2016 following academic training in biological chemistry and protein engineering and five years in industry focused on the directed evolution of therapeutic enzymes. I was instantly attracted to the rigorous scientific focus, collaborative atmosphere, and the abundant creativity of my prospective (now current) colleagues, along with the ability to translate scientific findings to actual human medicines. In the department of Antibody Engineering my group focuses on the development of complex biologics and bioconjugates to enable targeted biology that isn’t addressable in other ways.

Postdoctoral Mentor

I’m always excited to mentor post docs at Genentech. The unique environment here offers postdocs the opportunity to contribute to basic science while being immersed in both foundational and translational research. I find that collaborating with the next generation of scientists helps to ground me in fundamental elements of biochemistry while exploring emerging approaches in biotherapeutic discovery. Together this allows us to answer important questions about approaches

Featured Publication

Antibody targeting of E3 ubiquitin ligases for receptor degradation

Nature, 610, 182-189 (2022)

AMarei, H; Tsai, W. T.; Kee, S.;….Agard, NJ;* de Sousa e Melo, F*
*Co-corresponding authors