"Every day, I find inspiration working with teams passionate about the science and ultimately its translation into life-changing therapies for patients."
As a chemistry graduate student I visited and aspired to come work at Genentech and contribute to the mission of developing innovative medicines to help address unmet medical needs. My background research was around utilization of mass spectrometry for the structural characterization and quantitation of complex biological macromolecules such as glycosoaminoglycans.
After earning my Ph.D. in Chemistry, I joined Genentech in 2005 as an Associate Scientist to support the bioanalysis of our antibody-drug conjugate (ADC) programs. It has been a great opportunity to be pioneering in our field, and within our group applying both small and large molecule bioanalytical mass spectrometry to a breadth of programs.
I am grateful to be working in an organization with access to cutting edge instrumentation, smart, committed colleagues, and a collaborative, science-driven culture. Every day, I find inspiration working with teams passionate about the science and ultimately its translation into life-changing therapies for patients. Certainly some of the most motivating and rewarding experiences for me working at Genentech are actually seeing and hearing from patients who have benefited from these efforts.
My group is interested in the design of LC-MS based bioanalytical strategies for the characterization of antibody-drug conjugates (ADCs) and other biotherapeutics. We focus on the development, evaluation, and implementation of bioanalytical LC-MS methods to characterize ADC biopharmaceuticals, quantify therapeutic antibody and drug levels, as well as characterize catabolites in a variety of biological matrices.