Robby Weimer - Executive Director and Senior Principal Scientist, Biomedical Imaging

Robby Weimer

Executive Director and Senior Principal Scientist, Biomedical Imaging

Postdoc Mentor
"The beauty of optical imaging is the breadth of instrumentation and reporters that have been developed to enable visualization of structures from the cm to sub-micron range in vivo."
Years at Genentech
Publications at Genentech
Awards & Honors

I joined Genentech in 2006, and have been impressed with its collaborative environment, world-class science and continued focus on clinical questions. My lab collaborates across the research and early clinical development organizations. Our goal is to develop and implement imaging-based technologies to enable in vivo studies of disease biology and potential therapeutic approaches.

Postdoctoral Mentor

The postdoctoral program at Genentech provides a unique and exciting training opportunity. I am interested in understanding the mechanisms that regulate the stability of neuronal synaptic connections in vivo. Postdoctoral projects within my lab are focused on understand cell intrinsic and extrinsic pathways that influence the stability of these connections both in naive and disease paradigms. We rely on morphological and functional 2-photon in vivo imaging paradigms in combination with molecular genetic manipulations to study the interplay between neurons and glia in regulating synaptic connectivity.

Featured Publication

A Death Receptor 6-Amyloid Precursor Protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer’s disease-related patholophysiology in murine models.

J. Neurosci. 2014 34(19): 6425-6437.

Kallop, D., Meilandt, W., Gogineni, A., Easley-Neal, C., Wu, T., Jubb, A.M., Yaylaoglu, M., Mehrdad, S., Tessier-Lavigne, M., Scearce-Leive, K. and Weimer, R.M