Teemu Junttila
Principal Scientist, Translational Oncology
15
Years at Genentech
18
Publications
I joined Genentech in 2006, initially as a post doctoral fellow. I transitioned to leading a research team in 2010. What attracted me to Genentech the most, and still does, is the unique opportunity to be involved in a drug discovery project from concept all the way to clinical development. The immediate proximity between discovery scientists and clinical scientists allows for unique synergy - my research can be rapidly guided by clinical signals without delay, which I find extremely motivating and rewarding. My role is to lead large molecule biology research that translates new antibody engineering technologies into oncology therapeutics. Currently, we are focusing on bispecific antibodies that can be used to redirect T cells to attack tumors.
Featured Publication
Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing.
Cancer Cell. 2017 Mar 13;31(3):383-395.
Li J, Stagg NJ, Johnston J, Harris MJ, Menzies SA, DiCara D, Clark V, Hristopoulos M, Cook R, Slaga D, Nakamura R, McCarty L, Sukumaran S, Luis E, Ye Z, Wu TD, Sumiyoshi T, Danilenko D, Lee GY, Totpal K, Ellerman D, Hötzel I, James JR, Junttila TT.
Publications
Target arm affinities determine preclinical efficacy and safety of anti-HER2/CD3 bispecific antibody
JCI insight, ISSN: 23793708
Karin Staflin; Christina L. Zuch de Zafra; Leah Schutt; Vanessa Clark; Fiona Zhong; Maria Hristopoulos; Robyn Clark; Ji Li; Mary Mathieu; Xiaocheng Chen; Jennifer Johnston; Justin Low; Ryan Ybarra; Dion Slaga; Jihong Yang; Ayse Meric Ovacik; Noel Dybdal; Klara Totpal; Melissa Junttila; Diego Ellerman; Genee Lee; Mark Dennis; Rodney Prell; Teemu Junttila
Science Translational Medicine, ISSN: 19466242 19466234
Ji Li; Robert Piskol; Ryan Ybarra; Ying-Jiun J. Chen; Jason Li; Dion Slaga; Maria Hristopoulos; Robyn Clark; Zora Modrusan; Klara Totpal; Melissa Junttila; Teemu Junttila
Cell Death and Differentiation, ISSN: 14765403 13509047
Jason Long; Matthew Wongchenko; Dorothee Nickles; Wei-Jen Chung; Bu-Er Wang; Johannes Riegler; Ji Li; Jeff Eastham; Zora Modrusan; Teemu Junttila; Rick Carano; Oded Foreman; Yibing Yan; Melissa Junttila
Clinical Cancer Research, ISSN: 15573265 10780432
Ji Li; Ryan Ybarra; Judy Mak; Aurelie Herault; Patricia De Almeida; Alfonso Arrazate; James Ziai; Klara Totpal; Melissa Junttila; Kevin B. Walsh; Teemu Junttila
Science Translational Medicine, ISSN: 19466242 19466234
Dion Slaga; Diego Ellerman; Twyla Lombana; Rajesh Vij; Ji Li; Maria Hristopoulos; Robyn Clark; Jennifer Johnston; Amy Shelton; Elaine Mai; Kapil Gadkar; Amy A. Lo; James T. Koerber; Klara Totpal; Prell; Genee Lee; Christoph Spiess; Teemu Junttila
Molecular Cancer Therapeutics, ISSN: 15388514 15357163
Danielle Mandikian; Nene Takahashi; Amy A. Lo; Ji Li; Jeff Eastham; Dion Slaga; Jason Ho; Maria Hristopoulos; Robyn Clark; Klara Totpal; Kedan Lin; Sean B. Joseph; Mark Dennis; Saileta Prabhu; Teemu Junttila; Andy Boswell
mAbs, ISSN: 19420870 19420862
Ayse Meric Ovacik; Ji Li; Marie Lemper; Dimitry Danilenko; Nicola Stagg; Mary Mathieu; Diego Ellerman; Vinita Gupta; Navdeep Kalia; Trung Nguy; Vicki Plaks; Clarissa David Johnson; Weiru Wang; Jochen Brumm; Bernard Fine; Teemu Junttila; Kedan Lin; Paul Carter; Saileta Prabhu; Christoph Spiess; Amrita Kamath
mAbs, ISSN: 19420870
Sanket Patke; Ji Li; Peiyin Wang; Dion Slaga; Jennifer Johnston; Sunil Bhakta; Siler Panowski; Laura Sun; Teemu Junttila; Justin Scheer; Diego Ellerman
Cancer Cell, ISSN: 18783686
Ji Li; Nicola Stagg; Jennifer Johnston; Michael J. Harris; Sam A. Menzies; Danielle DiCara; Vanessa Clark; Maria Hristopoulos; Ryan Cook; Dion Slaga; Rin Nakamura; Luke McCarty; Sid Sukumaran; Elizabeth Luis; Zhengmao Ye; Thomas D. Wu; Teiko Sumiyoshi; Dimitry Danilenko; Genee Lee; Klara Totpal; Diego Ellerman; Isidro Hotzel; John R. James; Teemu Junttila
mAbs, ISSN: 19420870
Michael Dillon; Yiyuan Yin; Jianhui Zhou; Luke McCarty; Diego Ellerman; Dion Slaga; Teemu Junttila; Guanghui Han; Wendy Sandoval; Meric A. Ovacik; Kedan Lin; Zhilan Hu; Amy Shen; Jacob E. Corn; Christoph Spiess; Paul Carter
Science Translational Medicine, ISSN: 19466242
Laura Sun; Diego Ellerman; Mary Mathieu; Maria Hristopoulos; Xiaocheng Chen; Yijin Li; Xiaojie Yan; Robyn Clark; Art Reyes; Eric Stefanich; Elaine Mai; Judy Young; Clarissa Johnson; Mahrukh Huseni; Grace Wang; Yvonne Chen; Peiyin Wang; Hong Wang; Noel Dybdal; Wayne Chu; Nicholas Chiorazzi; Justin Scheer; Teemu Junttila; Klara Totpal; Mark Dennis; Allen Ebens
Cancer immunology research, ISSN: 23266074
Scot Liu; Cecile Chalouni; Judy Young; Teemu Junttila; Mark Sliwkowski; John B. Lowe (Path)
Cancer Research, ISSN: 15387445
Teemu Junttila; Ji Li; Jennifer Johnston; Maria Hristopoulos; Robyn Clark; Diego Ellerman; Bu-Er Wang; Yijin Li; Mary Mathieu; Ginny (Guangmin) Li; Judy Young; Elizabeth Luis; Gail Phillips; Eric Stefanich; Christoph Spiess; Andy Polson; Bryan Irving; Justin Scheer; Melissa Junttila; Mark Dennis; Robert Kelley; Klara Totpal; Allen Ebens
Cancer Cell, ISSN: 15356108
Teemu Junttila; Rob Akita; Kathryn Parsons-Reponte; Carter Fields; Gail Phillips; Lori Friedman; Deepak Sampath; Mark Sliwkowski
Breast Cancer Research and Treatment, ISSN: 01676806
Teemu Junttila; Ginny (Guangmin) Li; Kathryn Parsons-Reponte; Gail Phillips; Mark Sliwkowski
Duodecim; lääketieteellinen aikakauskirja, ISSN: 00127183
Teemu Junttila; Minna Tanner; Jorma Isola
Cancer Research, ISSN: 00085472
Teemu Junttila; Kathryn Parsons-Reponte; Christine Olsson; Yanmei Lu; Yan Xin; Julie Theriault; Lisa Crocker; Ollie Pabonan; Tomasz Baginski; Gloria Meng; Klara Totpal; Robert Kelley; Mark Sliwkowski
Cancer Cell, ISSN: 15356108
Teemu Junttila; Rob Akita; Kathryn Parsons-Reponte; Carter Fields; Gail Phillips; Lori Friedman; Deepak Sampath; Mark Sliwkowski
Education
- University of Turku, Finland , PhD in Medical Biochemistry – 2005