Tim Wilson
Distinguished Scientist Development, Oncology Biomarker Development
"It is very exciting to be a contributor to cross-functional, multifaceted teams with the same goal in mind – to bring the best anti-cancer medicines to patients that need them the most."
13
Years at Genentech
48
Publications at Genentech
I joined the Oncology Biomarker Development group at Genentech in 2011, following my postdoctoral research at Massachusetts General Hospital / Harvard Medical School. I was attracted to Genentech as I had a passion to translate pre-clinical research into therapies for biomarker-defined patient populations.
Predictive biomarkers are critical to the vision of precision medicine. My role at Genentech is to develop and test biomarker hypotheses to enable clinical development of experimental medicines in the most appropriate patient populations.
Featured Publication
The Molecular Landscape of High-Risk Early Breast Cancer: Comprehensive Biomarker Analysis of a Phase III Adjuvant Population
npj Breast Cancer 2, Article number: 16022 (2016), doi:10.1038/npjbcancer.2016.22
Timothy R. Wilson, Jianjun Yu, Xuyang Lu, Jill M. Spoerke, Yuanyuan Xiao, Carol O’Brien, Heidi Savage, Ling-Yuh Huw, Wei Zou, Hartmut Koeppen, William F. Forrest, Jane Fridlyand, Ling Fu, Rachel Tam, Erica B. Schleifman, Teiko Sumiyoshi, Luciana Molinero, Garret M. Hampton, Joyce A. O’Shaughnessy and Mark R. Lackner
My Focus
My group focuses on two main areas: (1) to develop and implement robust biomarker strategies that enable clinical development of experimental therapeutics; and (2) to decipher the biomarker landscape of breast cancer to study biomarker prevalence and overlap, as well as to determine any prognostic implications associated with key patient subsets.
Genentech Publications
Genome Medicine, ISSN: 1756994X
Katherine E. Hutchinson; Jessica W. Chen; Heidi Savage; Thomas J. Stout; Frauke Schimmoller; Javier Cortés; Susan Dent; Nadia Harbeck; William Jacot; Ian E. Krop; Sally E. Trabucco; Smruthy Sivakumar; Ethan S. Sokol; Wilson
Clinical Cancer Research, ISSN: 15573265 10780432
Smruthy Sivakumar; Dexter X. Jin; Ruchita Rathod; Jeffrey S. Ross; Lewis C. Cantley; Maurizio Scaltriti; Jessica W. Chen; Katherine E. Hutchinson; Wilson; Ethan S. Sokol; Neil Vasan
Molecular Oncology, ISSN: 18780261 15747891
Jessica W. Chen; William Jacot; Javier Cortés; Ian E. Krop; Susan Dent; Nadia Harbeck; De Laurentiis; Diéras; Young-Hyuck Im; Thomas J. Stout; Frauke Schimmoller; Heidi Savage; Katherine E. Hutchinson; Wilson
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Rocky Diegmiller; Laurent Salphati; Bruno Alicke; Wilson; Thomas J. Stout; Marc Hafner
Clinical Cancer Research,
Geoffrey J. Lindeman; Tharu M. Fernando; Rebecca Bowen; Katarzyna J. Jerzak; Xinni Song; Thomas Decker; Frances Boyle; Steven McCune; Anne Armstrong; Catherine Shannon; Gianfilippo Bertelli; Ching-Wei Chang; Rupal Desai; Kushagra Gupta; Wilson; Aulde Flechais; Aditya Bardia
Clinical Cancer Research, ISSN: 15573265 10780432
Geoffrey J. Lindeman; Tharu M. Fernando; Rebecca Bowen; Katarzyna J. Jerzak; Xinni Song; Thomas Decker; Frances Boyle; Steven McCune; Anne Armstrong; Catherine Shannon; Gianfilippo Bertelli; Ching-Wei Chang; Rupal Desai; Kushagra Gupta; Wilson; Aulde Flechais; Aditya Bardia
Molecular Oncology, ISSN: 18780261 15747891
Rafal Dziadziuszko; Tiffany Hung; Kun Wang; Voleak Choeurng; Alexander Drilon; Robert C Doebele; Fabrice Barlesi; Charlie Wu; Lucas Dennis; Skoletsky; Ryan Woodhouse; Meijuan Li; Ching-Wei Chang; Brian Simmons; Todd Riehl; Wilson
Clinical Cancer Research, ISSN: 10780432
George Demetri; Filippo De Braud; Alexander Drilon; Siena; Manish R. Patel; Byoung Chul Cho; Stephen V. Liu; Myung-Ju Ahn; Chao-Hua Chiu; Jessica J. Lin; Koichi Goto; Jeeyun Lee; Lyudmila Bazhenova; Tom John; Marwan Fakih; Sant P. Chawla; Rafal Dziadziuszko; Takashi Seto; Sebastian Heinzmann; Bethany Pitcher; David Chen; Wilson; Christian Rolfo
Clinical Cancer Research, ISSN: 15573265 10780432
George Demetri; Filippo De Braud; Alexander Drilon; Siena; Manish R. Patel; Byoung Chul Cho; Stephen V. Liu; Myung-Ju Ahn; Chao-Hua Chiu; Jessica J. Lin; Koichi Goto; Jeeyun Lee; Lyudmila Bazhenova; Tom John; Marwan Fakih; Sant P. Chawla; Rafal Dziadziuszko; Takashi Seto; Sebastian Heinzmann; Bethany Pitcher; David Chen; Wilson; Christian Rolfo
Pathology International, ISSN: 14401827 13205463
Sophia L. Maund; Ethan S. Sokol; Armande Ang Houle; Jeffrey S. Ross; Wilson
CPT: Pharmacometrics and Systems Pharmacology,
Rocky Diegmiller; Laurent Salphati; Bruno Alicke; Wilson; Thomas J. Stout; Marc Hafner
Molecular Oncology, ISSN: 18780261 15747891
Rafal Dziadziuszko; Tiffany Hung; Kun Wang; Voleak Choeurng; Alexander Drilon; Robert C Doebele; Fabrice Barlesi; Charlie Wu; Lucas Dennis; Skoletsky; Ryan Woodhouse; Meijuan Li; Ching-Wei Chang; Brian Simmons; Todd Riehl; Wilson
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Rocky Diegmiller; Laurent Salphati; Bruno Alicke; Wilson; Thomas J. Stout; Marc Hafner
Thoracic Cancer, ISSN: 17597706
Logan C. Tyler; Anh T. Le; Nan Chen; Hala Nijmeh; Liming Bao; Wilson; David Chen; Brian Simmons; Kristen M. Turner; Dean Perusse; Shailaja Kasibhatla; Jason Christiansen; Arkadiusz Z. Dudek; Robert C Doebele
Thoracic Cancer, ISSN: 17597714 17597706
Logan C. Tyler; Anh T. Le; Nan Chen; Hala Nijmeh; Liming Bao; Wilson; David Chen; Brian Simmons; Kristen M. Turner; Dean Perusse; Shailaja Kasibhatla; Jason Christiansen; Arkadiusz Z. Dudek; Robert C Doebele
npj Precision Oncology, ISSN: 2397768X
Westphalen; Matthew G Krebs; Le Tourneau; Ethan S. Sokol; Sophia L. Maund; Wilson; Jin; Newberg; David Fabrizio; Veronese; Marlene Thomas; Filippo De Braud
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Rafal Dziadziuszko; Matthew G Krebs; Filippo De Braud; Siena; Alexander Drilon; Robert C Doebele; Manish R. Patel; Byoung Chul Cho; Stephen V. Liu; Myung-Ju Ahn; Chao-Hua Chiu; Anna F Farago; Chia-Chi Lin; Karapetis; Yu-Chung Li; Bann-Mo Day; David Chen; Wilson; Fabrice Barlesi
Annals of Oncology, ISSN: 15698041 09237534
Susan Dent; Javier Cortés; Im; Diéras; Nadia Harbeck; Ian E. Krop; Wilson; Na Cui; Frauke Schimmoller; Jerry Y. Hsu; Jing He; De Laurentiis; Sousa; Drullinsky; William Jacot
Clinical Cancer Research, ISSN: 15573265 10780432
Komal Jhaveri; Matthew T. Chang; Dejan Juric; Saura; Valentina Gambardella; Anton Melnyk; Manish R. Patel; Vincent Ribrag; Cynthia X. Ma; Raid Aljumaily; Philippe L. Bedard; Jasgit C. Sachdev; Lara Dunn; Won; John Bond; Surai Jones; Heidi Savage; Maurizio Scaltriti; Wilson; Michael C. Wei; David Hyman
Clinical Cancer Research, ISSN: 15573265 10780432
Patrick Y. Wen; Timothy F. Cloughesy; Alan G. Olivero; Kari M. Morrissey; Wilson; Xuyang Lu; Lars Mueller; Alexandre Coimbra; Benjamin M. Ellingson; Elizabeth Gerstner; Eudocia Q. Lee; Jordi Rodon
Clinical Cancer Research, ISSN: 15573265 10780432
Patrick Y. Wen; Timothy Cloughesy; Alan G. Olivero; Kari M. Morrissey; Wilson; Xuyang Lu; Lars Mueller; Alexandre Coimbra; Benjamin M. Ellingson; Elizabeth Gerstner; Eudocia Q. Lee; Jordi Rodon
The Lancet Oncology, ISSN: 14745488 14702045
Robert C Doebele; Alexander Drilon; Luis Paz-Ares; Siena; Alice T. Shaw; Anna F Farago; Collin M Blakely; Takashi Seto; Byoung Chul Cho; Diego Tosi; Benjamin Besse; Sant P Chawla; Lyudmila Bazhenova; John C. Krauss; Young Kwang Chae; Minal Barve; Ignacio Garrido-Laguna; Stephen V. Liu; Paul Conkling; Tom John; Marwan Fakih; Darren Sigal; Herbert H Loong; Gary L Buchschacher; Pilar Garrido; Jorge Nieva; Conor Steuer; Tobias R Overbeck; Daniel W. Bowles; Elizabeth Fox; Todd Riehl; Edna Chow-Maneval; Brian Simmons; Na Cui; Ann Johnson; Susan Eng; Wilson; George Demetri
The Lancet Oncology, ISSN: 14745488 14702045
Alexander Drilon; Siena; Rafal Dziadziuszko; Fabrice Barlesi; Matthew G Krebs; Alice T. Shaw; Filippo De Braud; Christian Rolfo; Myung-Ju Ahn; Jurgen Wolf; Takashi Seto; Byoung Chul Cho; Manish R. Patel; Chao-Hua Chiu; Tom John; Koichi Goto; Karapetis; Hendrick-Tobias Arkenau; Sang-We Kim; Yuichiro Ohe; Yu-Chung Li; Young Kwang Chae; Christine H Chung; Gregory A Otterson; Haruyasu Murakami; Chia-Chi Lin; Daniel S W Tan; Hans Prenen; Todd Riehl; Edna Chow-Maneval; Brian Simmons; Na Cui; Ann Johnson; Susan Eng; Wilson; Robert C Doebele
Molecular Cancer Therapeutics, ISSN: 15388514 15357163
Heather M. Moore; Heidi Savage; Carol O'Brien; Wei Zhou; Ethan S. Sokol; Michael E. Goldberg; Ciara Metcalfe; Lori S. Friedman; Lackner; Wilson
Science, ISSN: 10959203 00368075
Neil Vasan; Pedram Razavi; Jared L. Johnson; Hong Shao; Hardik Shah; Alesia Antoine; Erik Ladewig; Alexander Gorelick; Ting-Yu Lin; Eneda Toska; Guotai Xu; Abiha Kazmi; Matthew T. Chang; Barry S. Taylor; Maura N. Dickler; Komal Jhaveri; Sarat Chandarlapaty; Raul Rabadan; Ed Reznik; Melissa L. Smith; Robert Sebra; Frauke Schimmoller; Wilson; Lori S. Friedman; Lewis C. Cantley; Maurizio Scaltriti; Baselga
The Lancet Oncology, ISSN: 14745488 14702045
Saura; Dominik Hlauschek; Oliveira; Zardavas; Jallitsch-Halper; Lorena de la Peña; Nuciforo; Alberto Ballestrero; Dubsky; Janine M Lombard; Peter Vuylsteke; Carlos A Castaneda; Colleoni; Giuliano Santos Borges; Eva Ciruelos; Monica Fornier; Katalin Boer; Aditya Bardia; Wilson; Thomas J. Stout; Jerry Y. Hsu; Yi Shi; Martine Piccart; Michael Gnant; Baselga; Evandro De Azambuja
Journal of the National Cancer Institute, ISSN: 14602105 00278874
Michail Ignatiadis; Gert G.G.M. Van Den Eynden; Salgado Roberto; Marco Fornili; Yacine Bareche; Christine Desmedt; Rothé; Maetens; David Venet; Esther Holgado; Virginia McNally; Astrid Kiermaier; Heidi Savage; Wilson; Javier Cortés; Andreas Schneeweiss; Karen Willard-Gallo; Elia Biganzoli; Christos Sotiriou
Molecular Cancer Research, ISSN: 15573125 15417786
Wilson; Akshata R. Udyavar; Ching-Wei Chang; Jill M. Spoerke; Junko Aimi; Heidi Savage; Anneleen Daemen; O'Shaughnessy; Richard Bourgon; Lackner
Clinical Cancer Research, ISSN: 15573265 10780432
Maura N. Dickler; Saura; Donald A. Richards; Ian E. Krop; Andrés Cervantes; Philippe L. Bedard; Manish R. Patel; Pusztai; Oliveira; Alison Cardenas; Na Cui; Wilson; Thomas J. Stout; Michael C. Wei; Jerry Y. Hsu; Baselga
Cancer Discovery, ISSN: 21598290 21598274
Dejan Juric; Ian E. Krop; Ramesh K. Ramanathan; Wilson; Joseph A. Ware; Sandra M. Sanabria-Bohorquez; Heidi Savage; Deepak Sampath; Laurent Salphati; Ray Lin; Huan Jin; Hema Parmar; Jerry Y. Hsu; Daniel D. Von Hoff; Baselga
npj Breast Cancer, ISSN: 23744677
Wilson; Yu; Xuyang Lu; Jill M. Spoerke; Yuanyuan Xiao; Carol O’brien; Heidi Savage; Huw; Wei Zou; Koeppen; William F. Forrest; Jane Fridlyand; Ling Fu; Rachel Tam; Erica Schleifman; Teiko Sumiyoshi; Luciana L. Molinero; Garret M. Hampton; O'Shaughnessy; Lackner
Annals of Oncology, ISSN: 15698041 09237534
Baselga; Cortes Castan; De Laurentiis; Diéras; Nadia Harbeck; Hsu; Huan Jin; Frauke Schimmoller; Wilson; Im; William Jacot; Ian E. Krop; Sunil Verma
Annals of Oncology, ISSN: 15698041 09237534
Baselga; Cortes Castan; De Laurentiis; Diéras; Nadia Harbeck; Jerry Y. Hsu; Jin; Frauke Schimmoller; Wilson; Im; William Jacot; Ian E. Krop; Sunil Verma
Annals of Oncology, ISSN: 15698041 09237534
Fumagalli; Wilson; Roberto Salgado; Xuyang Lu; Yu; Carol O'Brien; Kimberly Walter; Huw; Carmen Criscitiello; Laios; Jose; Brown; Rothé; Maetens; Zardavas; Peter Savas; Denis Larsimont; Martine Piccart; Stefan Michiels; Lackner; Christos Sotiriou; Sherene Loi
Nature Communications, ISSN: 20411723
Jill M. Spoerke; Steven Gendreau; Kimberly Walter; Jiaheng Qiu; Wilson; Heidi Savage; Junko Aimi; Mika K. Derynck; Meng Chen; Iris Chan; Lukas Amler; Garret M. Hampton; Stephen Johnston; Ian E. Krop; Schmid; Lackner
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Schmid; Sarah Pinder; Duncan Wheatley; Jane Macaskill; Charles Zammit; Jennifer Hu; Robert Price; Nigel Bundred; Sirwan Hadad; Alice Shia; Shah-Jalal Sarker; Louise Lim; Patrycja Gazinska; Natalie Woodman; Darren Korbie; Matt Trau; Paul Mainwaring; Steven Gendreau; Lackner; Mika K. Derynck; Wilson; Hannah Butler; Gemma Earl; Parker; Arnie Purushotham; Alastair Thompson
Annals of Oncology, ISSN: 15698041 09237534
Diéras; Mario Campone; Denise A. Yardley; Romieu; Vicente Valero; Isakoff; Koeppen; Wilson; Yuanyuan Xiao; David S. Shames; Mocci; Meng Chen; Schmid
Breast Cancer Research and Treatment, ISSN: 15737217 01676806
Wilson; Yuanyuan Xiao; Jill M. Spoerke; Jane Fridlyand; Koeppen; Eloisa Fuentes; Huw; Ilma Abbas; Arjan Gower; Erica Schleifman; Rupal Desai; Ling Fu; Teiko Sumiyoshi; Joyce A. O’Shaughnessy; Garret M. Hampton; Lackner
Cancer Research, ISSN: 15387445 00085472
Debasish Raha; Wilson; Jing Peng; David Peterson; Peng Yue; Marie Evangelista; Catherine Wilson; Mark Merchant; Jeffrey Settleman
Cancer Research, ISSN: 15387445 00085472
Debasish Raha; Wilson; Jing Peng; David Peterson; Peng Yue; Marie Evangelista; Catherine Wilson; Mark Merchant; Jeffrey Settleman
PLoS ONE, ISSN: 19326203
Erica Schleifman; Rupal Desai; Jill M. Spoerke; Yuanyuan Xiao; Cheryl Wong; Ilma Abbas; Carol O'Brien; Rajesh Patel; Teiko Sumiyoshi; Ling Fu; Rachel Tam; Koeppen; Wilson; Rajiv Raja; Garret M. Hampton; Lackner
Genes and Cancer, ISSN: 19476027 19476019
Kyle A. Edgar; Lisa Crocker; Eric Cheng; Marie-Claire Wagle; Matthew Wongchenko; Yibing Yan; Wilson; Nicholas A. Dompe; Richard M. Neve; Marcia Belvin; Deepak Sampath; Lori S. Friedman; Jeffery J. Wallin
Breast Cancer Research and Treatment, ISSN: 15737217 01676806
Arthur; Turnbull; Renshaw; Keys; Thomas; Wilson; Lackner; Sims; Dixon
PLoS ONE, ISSN: 19326203
David S. Shames; Juliet Carbon; Kimberly Walter; Adrian M. Jubb; Cleopatra Kozlowski; Thomas Januario; An Do; Ling Fu; Yuanyuan Xiao; Rajiv Raja; Brittany Jiang; Ashi Malekafzali; Howard M. Stern; Jeffrey Settleman; Wilson; Garret M. Hampton; Robert Yauch; Andrea Pirzkall; Lukas Amler
Nature, ISSN: 00280836 14764687
Wilson; Jane Fridlyand; Yibing Yan; Elicia M. Penuel; Luciana Burton; Emily Chan; Jing Peng; Eva Lin; Wang; Jeffrey A. Sosman; Antoni Ribas; Jiang Li; John Moffat; Daniel P. Sutherlin; Koeppen; Mark Merchant; Richard M. Neve; Jeffrey Settleman
Growth Factors, ISSN: 08977194 10292292
Kristy J. Wilson; Christopher Mill; Sydney Lambert; Jennifer Buchman; Wilson; Victor Hernandez-Gordillo; Richard M. Gallo; Laura M.C. Ades; Jeffrey E. Settleman; David J. Riese II
Future Oncology, ISSN: 17448301 14796694
Lackner; Wilson; Jeffrey Settleman
Cancer Cell, ISSN: 18783686 15356108
Wilson; Diana Y. Lee; Berry; David S. Shames; Jeffrey Settleman
Education
- Genentech, Postdoctoral Fellow – 2011
- Massachusetts General Hospital/Harvard Medical School, Postdoctoral Fellow – 2010
- Queen’s University, Belfast, Postdoctoral Fellow – 2008
- Queen’s University, Belfast, Ph.D. in Cancer Biology – 2005
- University of Ulster, B.Sc. in Applied Biochemical Sciences – 2002