"Life is a journey filled with inspirations. I feel myself inspired every day at Genentech."
I joined Genentech in the summer of 2020. Prior to that, I was a faculty member at UCSD, starting as an Assistant Professor and promoted to Associate Professor with tenure. I made this career shift because I believe that Genentech is a very unique place that fosters both cutting-edge scientific research and ground-breaking therapies for patients. My role at Genentech is to lead a group focusing on dissecting tissue and tumor immune microenvironment, striving to identify novel therapeutic targets and the underlying mechanisms.
I have been very fortunate to have highly talented postdocs in my lab since I started my career as an independent investigator. Genentech offers a world-class postdoc program providing an exceptional environment for postdocs to reach their full potential. I feel privileged to be part of this program. It is a very rewarding experience.
Immunity 54:903-15, 2021.
Nat Rev Endocrinol. 2020 Feb;16(2):81-90
Cell Metabolism 2019. 39: 457-474.
Cell Reports 2019. 27:3629-3645.
My group is interested in understanding how immune cells shape tissue microenvironment. We apply tools of mouse genetics, single cell genomic and imaging techniques to dissect the crosstalk between immune cells and tissue parenchymal cells or tumor cells.
We aim to identify tissue-specific factors that regulate the migration, distribution and function of immune cells and the dynamic interactions between immune cells and non-immune cells under physiological and pathophysiological conditions.