Zora Modrusan
Associate Director, Next Generation Sequencing
17
Years at Genentech
163
Publications
My position at Genentech provides a great opportunity to collaborate with research groups engaged in the validation and development of new therapeutic targets. Working with diverse groups of scientists and having access to cutting edge technology are the key elements that make my job gratifying.
Featured Publication
Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.
Nature Genetics 2015 Jan;47(1):13-21.
Durinck S, Stawiski EW, Pavía-Jiménez A, Modrusan Z, Kapur P, Jaiswal BS, Zhang N, Toffessi-Tcheuyap V, Nguyen TT, Pahuja KB, Chen YJ, Saleem S, Chaudhuri S, Heldens S, Jackson M, Peña-Llopis S, Guillory J, Toy K, Ha C, Harris CJ, Holloman E, Hill HM, Stinson J, Rivers CS, Janakiraman V, Wang W, Kinch LN, Grishin NV, Haverty PM, Chow B, Gehring JS, Reeder J, Pau G, Wu TD, Margulis V, Lotan Y, Sagalowsky A, Pedrosa I, de Sauvage FJ, Brugarolas J, Seshagiri S.
My Focus
I joined the Molecular Biology Department at Genentech in 2004 as a scientist heading a core technology lab that provides microarray support for the entire company. My lab currently focuses on developing and providing a high-throughput methodology for profiling genomes and trascriptomes by Next Generation Sequencing (NGS) technologies. We developed an automated high throughput NGS library generation process that enables the processing of hundreds of DNA/RNA samples. We also support many collaborative research projects focused on large scale cancer genomics. Our latest technology advancement is focused on single cell genomics where we perform highly parallel, genome-wide profiling of thousands of single cells to gain a better understanding of their biological diversity.
Prior to Genentech, I held similar scientist positions and lead the technology development projects on microarrays and gene-based detection assays at Incyte Genomics and ID Biomedical, respectively.
Publications
Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade
Journal for ImmunoTherapy of Cancer,
Romain Banchereau; Avantika S. Chitre; Alexis Scherl; Thomas Wu; Namrata S. Patil; Patricia De Almeida; Edward E. Kadel III; Shravan Madireddi; Amelia Au-Yeung; Chikara Takahashi; Jasmine Chen; Zora Modrusan; Jacqueline McBride; Rhea Nersesian; Ehab A. El-Gabry; Mark D. Robida; Jeffrey Hung; Marcin Kowanetz; Wei Zou; Mark McCleland; Patrick Caplazi; Shadi Toghi Eshgi; Hartmut Koeppen; Priti Hegde; Ira Mellman; Rod Mathews; Thomas Powles; Sanjeev Mariathasan; Jane Grogan; William E. O'Gorman
Cell Reports, ISSN: 22111247
Kimberle Shen; Mike Reichelt; Roxanne Kyauk; Hai Ngu; Yun-An A. Shen; Oded Foreman; Zora Modrusan; Brad A. Friedman; Morgan Sheng; Tracy J. Yuen
eLife, ISSN: 2050084X
Helen Tauc; Imilce A. Rodriguez-Fernandez; Jason Hackney; Michal Pawlak; Tal Ronnen Oron; Jerome Korzelius; Hagar F. Moussa; Subhra Chaudhuri; Zora Modrusan; Bruce A. Edgar; Heinrich Jasper
Cancer Discovery, ISSN: 21598290 21598274
Trang Pham; Thijs Hagenbeek; Ho-June Lee; Jason Li; Christopher M. Rose; Eva Lin; Mamie Yu; Scott E. Martin; Robert Piskol; Jennifer Lacap; Deepak Sampath; Victoria Pham; Zora Modrusan; Jennie Lill; Christiaan Klijn; Shiva Malek; Matthew T. Chang; Anwesha Dey
Clinical Cancer Research, ISSN: 15573265 10780432
Anneleen Daemen; Jonathan E. Cooper; Szymon Myrta; Matthew Wongchenko; Eva Lin; Jason E. Long; Oded Foreman; Zora Modrusan; Jarrod Tremayne; Cecile de la Cruz; Mark Merchant; Scott E. Martin; Yibing Yan; Melissa Junttila
NINJ1 mediates plasma membrane rupture during lytic cell death
Nature, ISSN: 00280836
Nobuhiko Kayagaki; Opher S. Kornfeld; Bettina L. Lee; Irma Stowe; Karen O’Rourke; Qingling Li; Wendy Sandoval; Donghong Yan; Jing Kang; Min Xu; Juan Zhang; Wyne P. Lee; Brent McKenzie; Gözde Ulas; Jian Payandeh; Meron Roose-Girma; Zora Modrusan; Rohit Reja; Meredith Sagolla; Joshua D. Webster; Vicky Cho; T. Daniel Andrews; Lucy X. Morris; Lisa A. Miosge; Christopher C. Goodnow; Edward M. Bertram; Vishva Dixit
Author Correction: High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade (Nature Medicine, (2020), 26, 5, (693-698), 10.1038/s41591-020-0860-1)
Nature Medicine, ISSN: 10788956
Kobe Yuen; L-F Liu; Vinita Gupta; Shravan Madireddi; Shilpa Keerthivasan; Congfen Li; Deepali Rishipathak; Patrick Williams; Edward E. Kadel III; Hartmut Koeppen; Ying-Jiun Chen; Zora Modrusan; Jane Grogan; Romain Banchereau; Ning Leng; AnnChristine Thåström; Xiadong Shen; Kenji Hashimoto; Darren Tayama; Michiel S Van Der Heijden; Jonathan E. Rosenberg; David McDermott; Thomas Powles; Priti Hegde; Mahrukh Huseni; Sanjeev Mariathasan
The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models
PLoS ONE,
Arna Katewa; Eric Suto; Jessica Hui; Jose Heredia; Jie Liang; Jason Hackney; Keith Anderson; Tuija Alcantar; Natasha Bacarro; Debra Dunlap; Jeffrey Eastham; Andres Paler Martinez; Xin Rairdan; Zora Modrusan; Wyne P. Lee; Cary Austin; Daniel Lafkas; Nico Ghilardi
Biotechnology Progress, ISSN: 15206033 87567938
Domingos Ng; Michelle Zhou; Dejin Zhan; Shirley Yip; Peggy Ko; Mandy Yim; Zora Modrusan; John Joly; Brad Snedecor; Mike Laird; Amy Shen
Nature Communications, ISSN: 20411723
Aswini Krishnan; Jean Berthelet; Emilie Renaud; Sebastian Rosigkeit; Ute Distler; Eric Stawiski; Jing Wang; Zora Modrusan; Marc Fiedler; Mariann Bienz; Stefan Tenzer; Arno Schad; Wilfried Roth; Bernd Thiede; Somasekar Seshagiri; Thomas J. Musholt; Krishnaraj Rajalingam
Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate
Nature Communications, ISSN: 20411723
Akhilesh Pandey; Eric Stawiski; Steffen Durinck; Harsha Gowda; Leonard Goldstein; Mustafa A. Barbhuiya; Markus S. Schröder; Sreelakshmi K. Sreenivasamurthy; Sun-Whe Kim; Sameer Phalke; Kushal Suryamohan; Kayla Lee; Papia Chakraborty; Vasumathi Kode; Xiaoshan Shi; Aditi Chatterjee; Keshava Datta; Aafaque A. Khan; Tejaswini Subbannayya; Jing Wang; Subhra Chaudhuri; Sanjiv Gupta; Braj Raj Shrivastav; Bijay Jaiswal; Satish S. Poojary; Shushruta Bhunia; Patricia Garcia; Carolina Bizama; Lorena Rosa; Wooil Kwon; Hongbeom Kim; Youngmin Han; Thakur Deen Yadav; Vedam Laxmi Ramprasad; Amitabha Chaudhuri; Zora Modrusan; Juan Carlos Roa; Pramod Kumar Tiwari; Jin-Young Jang; Somasekar Seshagiri
Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients
Nature Communications,
Tharu M. Fernando; Robert Piskol; Russell Bainer; Ethan S. Sokol; Sally E. Trabucco; Qing Zhang; Huong Trinh; Sophia L. Maund; Marc Kschonsak; Subhra Chaudhuri; Zora Modrusan; Tom Januario; Bob Yauch
Osteopontin Links Myeloid Activation and Disease Progression in Systemic Sclerosis
Cell Reports Medicine,
Xia Gao; Jim Jia; Anna Guttman; Daryle DePianto; Katrina B. Morshead; Kai-Hui Sun; Nandhini Ramamoorthi; Jason A. Vander Heiden; Zora Modrusan; Paul J. Wolters; Angelika Jahreis; Joe Arron; Dinesh Khanna; Thiru Ramalingam
Single-cell transcriptome profiling of the kidney glomerulus identifies key cell types and reactions to injury
Journal of the American Society of Nephrology, ISSN: 10466673
Jun-Jae Chung; Leonard Goldstein; Jasmine Chen; Jiyeon Lee; Webster; Meron Roose-Girma; Sharad C. Paudyal; Zora Modrusan; Anwesha Dey; Andrey Shaw
Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPβ in Microglia
Cell, ISSN: 00928674
Ada Ndoja; Rohit Reja; Seung-Hye Lee; Webster; Hai Ngu; Christopher M. Rose; Don Kirkpatrick; Zora Modrusan; Ying-Jiun Jasmine Chen; Debbie Dugger; Vineela Gandham; Luke Xie; Kim Newton; Vishva Dixit
Unstable mechanisms of resistance to inhibitors of escherichia coli lipoprotein signal peptidase
mBio, ISSN: 21612129
Homer Pantua; Elizabeth Skippington; Marie-Gabrielle Braun; Cameron Noland; Jingyu Diao; Yutian Peng; Susan Gloor; Donghong Yan; Jing Kang; Anand Kumar Katakam; Janina Reeder; Georgette Castanedo; Keira Garland; László Kömüves; Meredith Sagolla; Cary Austin; Jeremy Murray; Yiming Xu; Zora Modrusan; Min Xu; Emily Hanan; Sharookh Kapadia
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490
Filip Roudnicky; Jitao David Zhang; Bo Kyoung Kim; Nikhil J. Pandya; Yanjun Lan; Lisa Sach-Peltason; Heloise Ragelle; Pamela Strassburger; Sabine Gruener; Mirjana Lazendic; Sabine Uhles; Franco Revelant; Oliv Eidam; Gregor Sturm; Verena Kueppers; Klaus Christensen; Leonard Goldstein; Manuel Tzouros; Balazs Banfai; Zora Modrusan; Martin Graf; Christoph Patsch; Mark Burcin; Claas A. Meyer; Peter D. Westenskow; Chad A. Cowan
Cell Reports, ISSN: 22111247
Karpagam Srinivasan; Brad Friedman; Ainhoa Etxeberria; Melanie Huntley; Marcel van der Brug; Oded Foreman; Jonathan S. Paw; Zora Modrusan; Thomas G. Beach; Geidy E. Serrano; David Hansen
Cancer Research, ISSN: 15387445
Jonathan Harnoss; Adrien Le Thomas; Mike Reichelt; Ofer Guttman; Thomas Wu; Scot Marsters; Anna Shemorry; David Lawrence; David Kan; Ehud Segal; Mark Merchant; Klara Totpal; Lisa Crocker; Kathryn Mesh; Monika Dohse; Margaret Solon; Zora Modrusan; Joachim Rudolph; Hartmut Koeppen; Peter Walter; Avi Ashkenazi
High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade
Nature Medicine,
Kobe C. Yuen; L-F Liu; Vinita Gupta; Shravan Madireddi; Shilpa Keerthivasan; Congfen Li; Deepali Rishipathak; Patrick Williams; Edward E. Kadel III; Hartmut Koeppen; Ying-Jiun Chen; Zora Modrusan; Jane Grogan; Romain Banchereau; Ning Leng; AnnChristine Thåström; Xiadong Shen; Kenji Hashimoto; Darren Tayama; Michiel S Van Der Heijden; Jonathan E. Rosenberg; David McDermott; Thomas Powles; Priti Hegde; Mahrukh Huseni; Sanjeev Mariathasan
Nature, ISSN: 14764687 00280836
Thomas Wu; Shravan Madireddi; Patricia De Almeida; Romain Banchereau; Ying-Jiun J. Chen; Avantika S. Chitre; Eugene Chiang; Hina Iftikhar; William E. O’Gorman; Amelia Au-Yeung; Chikara Takahashi; Leonard Goldstein; Chungkee Poon; Shilpa Keerthivasan; Denise De Almeida Nagata; Xiangnan Du; Hyang-Mi Lee; Karl L. Banta; Sanjeev Mariathasan; Meghna Das Thakur; Mahrukh Huseni; Marcus Ballinger; Ivette Estay; Patrick Caplazi; Zora Modrusan; Lelia Delamarre; Ira Mellman; Richard Bourgon; Jane Grogan
Journal of Neuroscience, ISSN: 15292401 02706474
Bill Meilandt; Hai Ngu; Alvin Gogineni; Guita Lalehzadeh; Seung-Hye Lee; Karpagam Srinivasan; Jose Imperio; Tiffany Wu; Martin Weber; Agatha J. Kruse; Kimberly Stark; Pamela Chan; Mandy Kwong; Zora Modrusan; Brad Friedman; Justin Elstrott; Oded Foreman; Amy Easton; Morgan Sheng; X David V. Hansen
Immunity, ISSN: 10974180 10747613
Yi Zhou; Mingjian Fei; Gu Zhang; Wei-Ching Liang; WeiYu Lin; Yan Wu; Robert Piskol; John Brady; Erin McNamara; Haochu Huang; Juan Zhang; Jaehak Oh; Jaina M. Patel; Diana Jakubiak; Jeff Lau; Beth Blackwood; Daniel D. Bravo; Yongchang Shi; Jianyong Wang; Hong-Ming Hu; Wyne P. Lee; Rajiv Jesudason; Dewakar Sangaraju; Zora Modrusan; Keith Anderson; Soren Warming; Meron Roose-Girma; Minhong Yan
Heterogeneity of Satellite Cells Implicates DELTA1/NOTCH2 Signaling in Self-Renewal
Cell Reports,
Valeria Yartseva; Leonard Goldstein; Julia Rodman; Lance Kates; Mark Z. Chen; Jasmine Chen; Oded Foreman; Chris Siebel; Zora Modrusan; Andrew S. Peterson; Ana Jovičić
Cancer Discovery, ISSN: 21598290
Claudia Dominguez; Sören Müller; Shilpa Keerthivasan; Hartmut Koeppen; Jeffrey Hung; Sarah Gierke; Beatrice Breart; Oded Foreman; Travis Bainbridge; Alessandra Castiglioni; Yasin Senbabaoglu; Zora Modrusan; Yuxin Liang; Melissa Junttila; Christiaan Klijn; Richard Bourgon; Shannon Turley
Cell Reports, ISSN: 22111247
Luz D. Orozco; Hsu-Hsin Chen; Christian Cox; Ken Katschke; Rommel Arceo; Carmina Espiritu; Patrick Caplazi; Sarajane Saturnio Nghiem; Jasmine Chen; Zora Modrusan; Amy Stockwell; Leonard Goldstein; Christine Clarke; Tushar Bhangale; Brian Yaspan; Marion Jeanne; Michael Townsend; Menno van Lookeren Campagne; Jason Hackney
mAbs, ISSN: 19420870 19420862
Yi-Chun Hsiao; Jasmine Chen; Leonard Goldstein; Jia Wu; Zhonghua Lin; Kellen Schneider; Subhra Chaudhuri; Aju Antony; Kanika Bajaj Pahuja; Zora Modrusan; Dhaya Seshasayee; Somasekar Seshagiri; Isidro Hotzel
Nature Genetics, ISSN: 15461718 10614036
Kushal Suryamohan; Sajesh P. Krishnankutty; Joe Guillory; Matthew Jevit; Markus S. Schröder; Meng Wu; Boney Kuriakose; Oommen K. Mathew; Rajadurai C. Perumal; Ivan Koludarov; Leonard Goldstein; Kate Senger; Mandumpala Davis Dixon; Dinesh Velayutham; Derek Vargas; Subhra Chaudhuri; Megha Muraleedharan; Ridhi Goel; Jasmine Chen; Aakrosh Ratan; Peter Liu; Brendan Faherty; Guillermo de la Rosa; Hiroki Shibata; Miriam Baca; Meredith Sagolla; James Ziai; Gus A. Wright; Domagoj Vucic; Sangeetha Mohan; Aju Antony; Jeremy Stinson; Donald S. Kirkpatrick; Rami Hannoush; Steffen Durinck; Zora Modrusan; Eric Stawiski; Kristen Wiley; Terje Raudsepp; R. Manjunatha Kini; Arun Zachariah; Somasekar Seshagiri
Breast Cancer Research, ISSN: 1465542X 14655411
Wenlin Yuan; Leonard Goldstein; Steffen Durinck; Jasmine Chen; Thong Tom Nguyen; Noelyn Kljavin; Ethan S. Sokol; Eric Stawiski; Benjamin Haley; James Ziai; Zora Modrusan; Somasekar Seshagiri
Adaptive adipose tissue stromal plasticity in response to cold stress and antibody-based metabolic therapy
Scientific Reports,
Joshua C. Chang; Steffen Durinck; Mark Chen; Nadia Martinez-Martin; Jingli A. Zhang; Isabelle Lehoux; Hong Li; May Lin; Jiansheng Wu; Travis Bainbridge; James A. Ernst; Sree Ranjani Ramani; Sairupa Paduchuri; Lance Kates; Margaret Solon; Matthew B. Buechler; Alessandra Castiglioni; Minh Thai; Beatrice Breart; Zora Modrusan; Andrew S. Peterson; Shannon Turley; Jun Sonoda
Communications Biology, ISSN: 23993642
Leonard Goldstein; Jasmine Chen; Jia Wu; Subhra Chaudhuri; Yi-Chun Hsiao; Kellen Schneider; Kam Hon Hoi; Zhonghua Lin; Steve Guerrero; Bijay Jaiswal; Jeremy Stinson; Aju Antony; Kanika Bajaj; Dhaya Seshasayee; Zora Modrusan; Isidro Hotzel; Somasekar Seshagiri
Nature, ISSN: 14764687 00280836
Kim Newton; Kate Wickliffe; Maltzman; Debbie Dugger; Rohit Reja; Yue Zhang; Meron Roose-Girma; Zora Modrusan; Meredith Sagolla; Webster; Vishva Dixit
Science Translational Medicine, ISSN: 19466242 19466234
Ji Li; Robert Piskol; Ryan Ybarra; Ying-Jiun J. Chen; Jason Li; Dion Slaga; Maria Hristopoulos; Robyn Clark; Zora Modrusan; Klara Totpal; Melissa Junttila; Teemu Junttila
Cell, ISSN: 10974172
Jane Guan; Wei Zhou; Marc Hafner; Robert Blake; Cecile Chalouni; Irene P. Chen; Tom De Bruyn; Jennifer Giltnane; Steven J. Hartman; Amy Heidersbach; Rene Houtman; Ellen Ingalla; Kategaya; Tracy Kleinheinz; Jun Li; Scott E. Martin; Zora Modrusan; Michelle Nannini; Jason Oeh; Savita Ubhayakar; Xiaojing Wang; Ingrid Wertz; Amy Young; Mamie Yu; Deepak Sampath; Jeffrey H. Hager; Lori Friedman; Anneleen Daemen; Ciara Metcalfe
Genes, ISSN: 20734425
Ze Zhang; Danni Luo; Xue Zhong; Jin Huk Choi; Yuanqing Ma; Stacy Wang; Elena Mahrt; Wei Guo; Eric Stawiski; Zora Modrusan; Somasekar Seshagiri; Payal Kapur; Gary C. Hon; James Brugarolas; Tao Wang
Coexpression of inhibitory receptors enriches for activated and functional CD8+ T cells in murine syngeneic tumor models
Cancer immunology research, ISSN: 23266066
Huizhong Xiong; Stephanie Mittman; Ryan Rodriguez; Patricia Pacheco-Sanchez; Marina Moskalenko; Yagai Yang; Justin Elstrott; Alex Ritter; Sören Müller; Dorothee Nickles; Teresita L. Arenzana; Aude-Helene Capietto; Lelia Delamarre; Zora Modrusan; Sascha Rutz; Ira Mellman; Rafael Cubas
eLife, ISSN: 2050084X
Ganapati Hegde; Cecile de la Cruz; Jennifer Giltnane; Lisa Crocker; Avinashnarayan Venkatanarayan; Gabriele Schaefer; Debra Dunlap; Joerg D. Hoeck; Robert Piskol; Florian Gnad; Zora Modrusan; Frederic De Sauvage; Chris Siebel; Erica Jackson
IRF2 transcriptionally induces GSDMD expression for pyroptosis
Science Signaling, ISSN: 19450877
Nobuhiko Kayagaki; Bettina L. Lee; Irma Stowe; Opher S. Kornfeld; Karen O'Rourke; Kathleen M. Mirrashidi; Benjamin Haley; Colin Watanabe; Meron Roose-Girma; Zora Modrusan; Sarah Kummerfeld; Rohit Reja; Yafei Zhang; Vicky Cho; Daniel Andrews; Lucy X. Morris; Christopher C. Goodnow; Edward M. Bertram; Vishva Dixit
Cell Reports, ISSN: 22111247
Denise De Almeida Nagata; Eugene Chiang; Suchit Jhunjhunwala; Patrick Caplazi; Vidhyalakshmi Arumugam; Zora Modrusan; Emily Chan; Mark Merchant; Lingyan Jin; David Arnott; Anthony Romero; Steven Magnuson; Karen Gascoigne; Jane Grogan
PLoS ONE, ISSN: 19326203
Mona Abed; Erik Verschueren; Hanna G. Budayeva; Peter Liu; Don Kirkpatrick; Rohit Reja; Sarah Kummerfeld; Webster; Sarah Gierke; Mike Reichelt; Keith R. Anderson; Robert J (Research) Newman; Meron Roose-Girma; Zora Modrusan; Hazal Pektas; Emin Maltepe; Kim Newton; Vishva Dixit
Science, ISSN: 10959203 00368075
Meng He; Mira S. Chaurushiya; Webster; Sarah Kummerfeld; Rohit Reja; Subhra Chaudhuri; Jasmine Chen; Zora Modrusan; Benjamin Haley; Debbie Dugger; Jeff Eastham; Shari Lau; Anwesha Dey; Roger Caothien; Meron Roose-Girma; Kim Newton; Vishva Dixit
Clinical Cancer Research, ISSN: 15573265 10780432
Robert Piskol; Ling-Yuh Huw; Ismail Sergin; Christiaan Kljin; Zora Modrusan; Doris Kim; Noelyn Kljavin; Nga Wan Rachel Tam; Rajesh Patel; Jeremy Burton; Elicia Penuel; Xueping Qu; Hartmut Koeppen; Teiko Sumiyoshi; Frederic De Sauvage; Mark Lackner; Felipe de Sousa e Melo; Omar Kabbarah
An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development
Nature Immunology, ISSN: 15292908
Prachi Bagadia; Xiao Huang; Tian-Tian Liu; Vivek Durai; Gary E. Grajales-Reyes; Maximilian Nitschke; Zora Modrusan; Jeffrey M. Granja; Ansuman T. Satpathy; Carlos G. Briseño; Marco Gargaro; Arifumi Iwata; Sunkyung Kim; Howard Y. Chang; Andrey S. Shaw; Theresa L. Murphy; Kenneth M. Murphy
Cell Death and Differentiation, ISSN: 14765403 13509047
Jason Long; Matthew Wongchenko; Dorothee Nickles; Wei-Jen Chung; Bu-Er Wang; Johannes Riegler; Ji Li; Jeff Eastham; Zora Modrusan; Teemu Junttila; Rick Carano; Oded Foreman; Yibing Yan; Melissa Junttila
Nature Communications, ISSN: 20411723
Hans Brightbill; Eric Suto; Nicole Blaquiere; Nandhini Ramamoorthi; Swathi Sujatha-Bhaskar; Emily Gogol; Georgette Castanedo; Benjamin T. Jackson; Youngsu Kwon; Susan Haller; Justin Lesch; Karin Bents; Christine Everett; Pawan Bir Kohli; Sandra Linge; Laura Christian; Kathy Barrett; Allan Jaochico; Leo Berezhkovskiy; Peter W. Fan; Zora Modrusan; Kelli Veliz; Michael Townsend; Jason DeVoss; Adam Johnson; Robert Godemann; Wyne Lee; Cary Austin; Brent McKenzie; Jason Hackney; James J. Crawford; Steven Staben; Moulay Hicham Alaoui-Ismaili; Lawren Wu; Nico Ghilardi
Ubiquitin ligase COP1 coordinates transcriptional programs that control cell type specification in the developing mouse brain
Proceedings of the National Academy of Sciences of the United States of America,
Kim Newton; Debbie Dugger; Arundhati Sengupta Ghosh; Ronald E. Ferrando; Felix Chu; Janet Tao; Wendy Lam; Susan Haller; Sara Chan; Susan Sa; Debra Dunlap; Jeff Eastham; Hai Ngu; Jeffrey Hung; Dorothy French; Webster; Brad Bolon; Jinfeng Liu; Rohit Reja; Sarah Kummerfeld; Ying-Jiun Chen; Zora Modrusan; Joe Lewcock; Vishva Dixit
Cancer Discovery, ISSN: 21598290 21598274
Tao Wang; Rong Lu; Payal Kapur; Bijay Jaiswal; Raquibul Hannan; Ze Zhang; Ivan Pedrosa; Jason Luke; He Zhang; Leonard Goldstein; Qurratulain Yousuf; Yi-Feng Gu; Tiffani McKenzie; Allison Joyce; Min S. Kim; Xinlei Wang; Danni Luo; Oreoluwa Onabolu; Christina Stevens; Zhiqun Xie; Mingyi Chen; Alexander Filatenkov; Jose Torrealba; Xin Luo; Wenbin Guo; Jingxuan He; Eric Stawiski; Zora Modrusan; Steffen Durinck; Somasekar Seshagiri; James Brugarolas
Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
Christopher P. Denton; Voon H Ong; Shiwen Xu; Haiyin Chen; Zora Modrusan; Robert Lafyatis; Dinesh Khanna; Angelika Jahreis; Jeffrey Siegel; Thierry Sornasse
Nature Chemical Biology, ISSN: 15524469 15524450
Aaron Nile; Felipe de Sousa e Melo; Susmith Mukund; Robert Piskol; Simon Hansen; Lijuan Zhou; Yingnan Zhang; Yue Fu; Emily Gogol; László Kömüves; Zora Modrusan; Stephane Angers; Yvonne Franke; Chris Koth; Wayne Fairbrother; Weiru Wang; Frederic De Sauvage; Rami Hannoush
Clinical Cancer Research, ISSN: 15573265 10780432
Bijay Jaiswal; Steffen Durinck; Eric Stawiski; Peter Yin; Weiru Wang; Eva Lin; John Moffat; Scott Martin; Zora Modrusan; Somasekar Seshagiri
Nature Methods, ISSN: 15487105 15487091
Keith R. Anderson; Maximilian Haeussler; Colin Watanabe; Vasant Janakiraman; Jessica Lund; Zora Modrusan; Jeremy Stinson; Qixin Bei; Andrew Buechler; Charles Yu; Sobha R. Thamminana; Lucinda Tam; Michael-Anne Sowick; Tuija Alcantar; Natasha O'Neil; Jinjie Li; Linda Ta; Lisa Lima; Meron Roose-Girma; Xin Rairdan; Steffen Durinck; Soren Warming
Nature Chemical Biology, ISSN: 15524469 15524450
Aaron Nile; Felipe de Sousa e Melo; Susmith Mukund; Robert Piskol; Simon Hansen; Lijuan Zhou; Yingnan Zhang; Yue Fu; Emily Gogol; László Kömüves; Zora Modrusan; Stephane Angers; Yvonne Franke; Chris Koth; Wayne Fairbrother; Weiru Wang; Frederic De Sauvage; Rami Hannoush
Science immunology, ISSN: 24709468
Teresita L. Arenzana; Steve Lianoglou; Akiko Seki; Celine Eidenschenk; Tommy Cheung; Dhaya Seshasayee; Thijs Hagenbeek; Arivazhagan Sambandam; Raj Noubade; Ivan Peng; Justin Lesch; Jason DeVoss; Xiumin Wu; Wyne P. Lee; Patrick Caplazi; Webster; Jinfeng Liu; Victoria Pham; David Arnott; Jennie Lill; Zora Modrusan; Anwesha Dey; Sascha Rutz
PLoS ONE, ISSN: 19326203
Elizabeth A. Germino; Joseph P. Miller; Lauri Diehl; Carter J. Swanson; Steffen Durinck; Zora Modrusan; Jeffrey H. Miner; Andrey Shaw
BMC Medical Genetics, ISSN: 14712350
Viswanathan Mohan; Venkatesan Radha; Thong Tom Nguyen; Eric Stawiski; Kanika Bajaj Pahuja; Leonard Goldstein; Jennifer A. Tom; Ranjit Mohan Anjana; Monica Beltran; Tushar Bhangale; Suresh Jahnavi; Radhakrishnan Chandni; Vijay Gayathri; Paul George; Na Zhang; Sakthivel Murugan; Sameer Phalke; Subhra Chaudhuri; Ravi Gupta; Jingli Zhang; Sam Santhosh; Jeremy Stinson; Zora Modrusan; Vedam Laxmi Ramprasad; Somasekar Seshagiri; Andrew Peterson
eLife, ISSN: 2050084X
Daniel J. Fazakerley; Rima Chaudhuri; Pengyi Yang; Ghassan J. Maghzal; Kristen C. Thomas; James R. Krycer; Sean J. Humphrey; Benjamin L. Parker; Kelsey H. Fisher-Wellman; Christopher C. Meoli; Nolan J. Hoffman; Ciana Diskin; James G. Burchfield; Mark J. Cowley; Warren Kaplan; Zora Modrusan; Ganesh Kolumam; Jean Y. H. Yang; Daniel L. Chen; Samocha-Bonet; Jerry R. Greenfield; Kyle L. Hoehn; Roland Stocker; David E. James
SUV420H2 is an epigenetic regulator of epithelial/ mesenchymal states in pancreatic cancer
Journal of Cell Biology, ISSN: 00219525
Manuel Viotti; Catherine Wilson; Mark McCleland; Hartmut Koeppen; Benjamin Haley; Suchit Jhunjhunwala; Christiaan Klijn; Zora Modrusan; David Arnott; Marie Classon; Daniel Stephan; Ira Mellman
Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models
Cell Reports,
Brad Friedman; Karpagam Srinivasan; Gai Ayalon; Bill Meilandt; Han Lin; Melanie Huntley; Yi Cao; Seung-Hye Lee; Patrick Haddick; Hai Ngu; Zora Modrusan; Jessica L. Larson; Josh Kaminker; Marcel van der Brug; David Hansen
The tumor suppressor BAP1 cooperates with BRAFV600E to promote tumor formation in cutaneous melanoma
Pigment Cell and Melanoma Research, ISSN: 1755148X 17551471
Webster; Trang Pham; Xiumin Wu; Nicolas W. Hughes; Zhongwu Li; Klara Totpal; Ho-June Lee; Philamer C. Calses; Mira S. Chaurushiya; Eric Stawiski; Zora Modrusan; Matthew T. Chang; Christopher Tran; Wyne P. Lee; Sreedevi Chalasani; Jeffrey Hung; Neeraj Sharma; Sara Chan; Kathy Hotzel; Eric Talevich; Alan Shain; Mengshu Xu; Jennie Lill; Vishva Dixit; Boris C. Bastian; Anwesha Dey
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
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Nature Biotechnology, ISSN: 15461696
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Immunology and Cell Biology, ISSN: 08189641
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Clinical Cancer Research, ISSN: 10780432
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Biochemical Journal, ISSN: 02646021
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EMBO Journal, ISSN: 02614189
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Deanna Wilson; Khanhky Phamluong; Li Li; Mei Sun; Tim Cao; Peter Liu; Zora Modrusan; Wendy Sandoval; Linda Rangell; Rick Carano; Andy Peterson; Mark Solloway
GLIA, ISSN: 08941491
Alexander Schulte; Hauke S. Günther; Heidi Phillips; Dirk Kemming; Tobias Martens; Samir Kharbanda; Robert Soriano; Zora Modrusan; Svenja Zapf; Manfred Westphal; Katrin Lamszus
Advances in Therapy, ISSN: 0741238X
Chinot; De La Motte Rouge; Moore; Zeaiter; Asha Das; Heidi Phillips; Zora Modrusan; Timothy Cloughesy
Science Translational Medicine, ISSN: 19466234
Bart Burington; Peng Yue; Lily Shi; Ranjana H. Advani; Jeffrey Lau; Jenille Tan; Susanna Stinson; Jeremy Stinson; Tom Januario; Sven De Vos; Stephen Ansell; Andres Forero-Torres; Grazyna Fedorowicz; Teddy Yang; Kristi Elkins; Changchun Du; Sankar Mohan; Nancy Yu; Zora Modrusan; Somasekar Seshagiri; Shang-Fan Yu; Ajay Pandita; Hartmut Koeppen; Dorothy French; Andy Polson; Rienk Offringa; Nancy Whiting; Allen Ebens; David Dornan
Journal of Immunology, ISSN: 00221767
David Choy; Barmak Modrek; Alexander Abbas; Sarah Kummerfeld; Hilary Clark; Lawren Wu; Grazyna Fedorowicz; Zora Modrusan; John V. Fahy; Prescott G. Woodruff; Joe Arron
BMC Medical Genomics, ISSN: 17558794
Serban Nacu; Wenlin Yuan; Zhengyan Kan; Deepali Bhatt; Celina Rivers; Jeremy Stinson; Brock Peters; Zora Modrusan; Kenneth Jung; Somasekar Seshagiri; Thomas Wu
Cancer Research, ISSN: 00085472
Peter Dijkgraaf; Bruno Alicke; Lasse Weinmann; Tom Januario; Kristina West; Zora Modrusan; Dan Burdick; Rich Goldsmith; Kirk Robarge; Dan Sutherlin; Suzie Scales; Stephen Gould; Bob Yauch; Frederic De Sauvage
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Marcin Kowanetz; Xiumin Wu; John Lee; Martha Tan; Thijs Hagenbeek; Xueping Qu; Lanlan Yu; Jed Ross; Nina Korsisaari; Tim Cao; Hani Bou-Reslan; Dara Kallop; Robby Weimer; Mary Ludlam; Josh Kaminker; Zora Modrusan; Nick Van Bruggen; Frank Peale; Rick Carano; Gloria Meng; Napoleone Ferrara
Inflammatory Bowel Diseases, ISSN: 10780998
Colin L. Noble; Alexander Abbas; Charles W. Lees; Jennine Cornelius; Karen Toy; Zora Modrusan; Hilary Clark; Ian D. Arnott; Ian D. Penman; Jack Satsangi; Lauri Diehl
Nature, ISSN: 00280836
Zhengyan Kan; Bijay Jaiswal; Jeremy Stinson; Vasant Janakiraman; Deepali Bhatt; Howard Stern; Peng Yue; Pete Haverty; Richard Bourgon; Jianbiao Zheng; Martin Moorhead; Subhra Chaudhuri; Lynn P. Tomsho; Brock Peters; Kanan Pujara; Shaun Cordes; David Davis; Victoria E. H. Carlton; Wenlin Yuan; Li Li; Weiru Wang; Charles Eigenbrot; Josh Kaminker; David Eberhard; Paul Waring; Stephan C. Schuster; Zora Modrusan; Zhen Zhang; David Stokoe; Frederic De Sauvage; Malek Faham; Somasekar Seshagiri
Nature, ISSN: 00280836
William Lee; Zhaoshi Jiang; Jinfeng Liu; Pete Haverty; Ying Guan; Jeremy Stinson; Peng Yue; Yan Zhang; Krishna P. Pant; Deepali Bhatt; Connie Ha; Stephanie Johnson; Michael I. Kennemer; Sankar Mohan; Igor Nazarenko; Colin Watanabe; Andrew B. Sparks; David Shames; Robert Gentleman; Frederic De Sauvage; Howard Stern; Ajay Pandita; Dennis G. Ballinger; Radoje Drmanac; Zora Modrusan; Somasekar Seshagiri; Zhen Zhang
Cancer Cell, ISSN: 15356108
Ruihuan Chen; Merry Nishimura; Stephanie Bumbaca; Samir Kharbanda; Bill Forrest; Ian Kasman; Joan Greve; Robert Soriano; Laurie Appling; Celina Rivers; Zora Modrusan; Serban Nacu; Steve Guerrero; Kyle Edgar; Jeffrey Wallin; Katrin Lamszus; Manfred Westphal; Susanne Heim; C. David James; Scott R. VandenBerg; Joseph F. Costello; Scott Moorefield; Cynthia J. Cowdrey; Michael D. Prados; Heidi Phillips
Cancer Cell, ISSN: 15356108
Bijay Jaiswal; Vasant Janakiraman; Noelyn Kljavin; Subhra Chaudhuri; Howard Stern; Weiru Wang; Zhengyan Kan; Hashem A. Dbouk; Brock Peters; Paul Waring; Trisha Dela Vega; Denise M. Kenski; Krista Bowman; Maria Lorenzo; Hong Li; Jiansheng Wu; Zora Modrusan; Jeremy Stinson; Mike Eby; Peng Yue; Josh Kaminker; Frederic De Sauvage; Jonathan M. Backer; Somasekar Seshagiri
Molecular Cancer Research, ISSN: 15417786
Eva Lin; Li Li; Ying Guan; Robert Soriano; Celina Rivers; Sankar Mohan; Ajay Pandita; Jerry (Zhijun) Tang; Zora Modrusan
BMC Medical Genomics, ISSN: 17558794
Grazyna Fedorowicz; Steve Guerrero; Thomas Wu; Zora Modrusan
Molecular Cancer Research, ISSN: 15417786
Barmak Modrek; Lin Ge; Ajay Pandita; Eva Lin; Sankar Mohan; Peng Yue; Steve Guerrero; William M. Lin; Thinh Pham; Zora Modrusan; Somasekar Seshagiri; Howard Stern; Paul Waring; Levi A. Garraway; John Chant; David Stokoe; Guy Cavet
PLoS ONE, ISSN: 19326203
Alexander Abbas; Kristen Wolslegel; Dhaya Seshasayee; Zora Modrusan; Hilary Clark
Cancer Research, ISSN: 00085472
Klaus Hoeflich; Sylvia Herter; Janet Tien; Kok Leong Wong; Leanne Ross; Jocelyn Chan; Carol O'Brien; Zora Modrusan; Somasekar Seshagiri; Mark Lackner; Howard Stern; Edna Choo; Lesley Murray; Lori Friedman; Marcia Belvin
Cancer Cell, ISSN: 15356108
Yongping Crawford; Ian Kasman; Lanlan Yu; Cuiling Zhong; Xiumin Wu; Zora Modrusan; Josh Kaminker; Napoleone Ferrara
Molecular Cancer Therapeutics, ISSN: 15357163
Yonglei Shang; Yifan Mao; Jennifer Batson; Suzie Scales; Gail Phillips; Mark Lackner; Klara Totpal; Simon Williams; Jihong Yang; Jerry (Zhijun) Tang; Zora Modrusan; Christine Tan; Wei-Ching Liang; Siao Tsai; Alex Vanderbilt; Kenji Kozuka; Klaus Hoeflich; Janet Tien; Sarajane Ross; Congfen Li; Hoon Lee Sang; An Song; Yan Wu; Daniel Stephan; Avi Ashkenazi; Jiping Zha
Gut, ISSN: 00175749
Colin L. Noble; Alexander Abbas; Jennine Cornelius; Charles W. Lees; Gwo-Tzer Ho; Karen Toy; Zora Modrusan; Pal; Zhong; Chalasani; Hilary Clark; Ian D. Arnott; Ian D. Penman; Jack Satsangi; Lauri Diehl
Clinical Cancer Research, ISSN: 10780432
Sherry X. Yang; Seth M. Steinberg; Dat Nguyen; Thomas Wu; Zora Modrusan; Sandra M. Swain
Cancer Research, ISSN: 00085472
Carol O'Brien; Guy Cavet; Ajay Pandita; Xiaolan Hu; Lauren Haydu; Sankar Mohan; Karen Toy; Celina Rivers; Zora Modrusan; Lukas Amler; Mark Lackner
Oncogene, ISSN: 09509232
Hauke S. Günther; Nils-Ole Schmidt; Heidi Phillips; Dirk Kemming; Samir Kharbanda; Robert Soriano; Zora Modrusan; Meissner; Manfred Westphal; Katrin Lamszus
Journal of Immunology, ISSN: 00221767
Ken Flanagan; Zora Modrusan; Jennine Cornelius; Arvind Chavali; Ian Kasman; László Kömüves; Lian Mo; Lauri Diehl
Nature Medicine, ISSN: 10788956
Yan Zheng; Patricia Valdez; Dimitry Danilenko; Yan Ling Hu; Susan M. Sa; Qian Gong; Alexander Abbas; Zora Modrusan; Nico Ghilardi; Frederic De Sauvage; Wenjun Ouyang
Molecular Cancer, ISSN: 14764598
Lucia Helena Carvalho; Ivan Smirnov; Gilson S. Baia; Zora Modrusan; Justin S. Smith; Peter Jun; Joseph F. Costello; Michael W. McDermott; Scott R. VandenBerg; Anita Lal
Differentiation, ISSN: 03014681
Xi-De Wang; Bu-Er Wang; Robert Soriano; Jiping Zha; Zhen Zhang; Zora Modrusan; Gerald R. Cunha; Wei-Qiang Gao
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Liliana Soroceanu; Samir Kharbanda; Ruihuan Chen; Robert Soriano; Kenneth D. Aldape; Anjan Misra; Jiping Zha; Bill Forrest; Janice M. Nigro; Zora Modrusan; Burt G. Feuerstein; Heidi Phillips
Journal of Immunology, ISSN: 00221767
Susan M. Sa; Patricia Valdez; Jiansheng Wu; Kenneth Jung; Fiona Zhong; Linda Hall; Ian Kasman; Jane Winer; Zora Modrusan; Dimitry Danilenko; Wenjun Ouyang
International Journal of Oncology, ISSN: 10196439
Klaus Hoeflich; Mike Eby; Bill Forrest; Daniel Gray; Janet Tien; Howard Stern; Lesley Murray; David Davis; Zora Modrusan; Somasekar Seshagiri
Cancer Cell, ISSN: 15356108
Heidi Phillips; Samir Kharbanda; Ruihuan Chen; Bill Forrest; Robert Soriano; Thomas Wu; Anjan Misra; Janice M. Nigro; Howard Colman; Liliana Soroceanu; P. Mickey Williams; Zora Modrusan; Burt G. Feuerstein; Kenneth D. Aldape
Developmental Biology, ISSN: 00121606
Xi-De Wang; Ching Ching Leow; Jiping Zha; Jerry (Zhijun) Tang; Zora Modrusan; Freddy Radtke; Michel Aguet; Frederic De Sauvage; Wei-Qiang Gao
Clinical Cancer Research, ISSN: 10780432
Bob Yauch; Tom Januario; David Eberhard; Guy Cavet; Wenjing Zhu; Ling Fu; Thinh Pham; Robert Soriano; Jeremy Stinson; Somasekar Seshagiri; Zora Modrusan; Chin-Yu Lin; Vince O'Neill; Lukas Amler
Nature Methods, ISSN: 15487091
Shawn C. Baker; Steven R. Bauer; Richard P. Beyer; James D. Brenton; Bud Bromley; John Burrill; Helen Causton; Michael P. Conley; Rosalie Elespuru; Michael Fero; Carole Foy; James Fuscoe; Xiaolian Gao; David Lee Gerhold; Patrick Gilles; Federico Goodsaid; Xu Guo; Joe Hackett; Richard D. Hockett; Pranvera Ikonomi; Rafael A. Irizarry; Ernest S. Kawasaki; Tamma Kaysser-Kranich; Kathleen Kerr; Gretchen Kiser; Walter H. Koch; Kathy Y. Lee; Chunmei Liu; Z. Lewis Liu; Anne Lucas; Chitra F. Manohar; Garry Miyada; Zora Modrusan; Helen Parkes; Raj K. Puri; Laura Reid; Thomas B. Ryder; Marc Salit; Raymond R. Samaha; Uwe Scherf; Timothy J. Sendera; Robert A. Setterquist; Leming Shi; Richard Shippy; Jesus V. Soriano; Elizabeth A. Wagar; Janet A. Warrington; Mickey P. Williams; Frederike Wilmer; Mike Wilson; Paul K. Wolber; Xiaoning Wu; Renata Zadro
Education
- ID Biomedical, Vancouver, BC., Postdoctoral Fellow – 1997
- University of British Columbia, Vancouver, BC., Botany Department, Ph.D. – 1995
- University of Zagreb, Zagreb, Croatia, Cell Biology, M. Sc. – 1988
- University of Zagreb, Zagreb, Croatia, Experimental Biology, B. Sc. – 1986