Andrew Chan - Senior Vice President, Research Biology

Andrew Chan

Senior Vice President, Research Biology

Postdoc Mentor
"Innovation requires an open mind and continued challenging of current paradigms. Discovery requires action based on innovation."
16
Years at Genentech
42
Publications
9
Awards & Honors

I joined Genentech in 2001 as senior director of immunology and antibody engineering, was named vice president and senior vice president of Research- Immunology in 2003 and 2007, respectively. In 2010, I was appointed senior vice president- Research Biology and oversee our research opportunities.

Genentech is one of the few places in the world where scientists have the ability to study basic biology, make new biological or technological discoveries, identify the pathogenic mechanisms driving human disease, discover new therapies and shepherd these therapies to launch and thereafter impact patients’ lives.

Postdoctoral Mentor

Postdoctoral training and mentorship is an essential part of a scientific career. It provides essential training and scientific experience for the mentee and an opportunity for the mentor to continue learning about new scientific paradigms and train the next generations of scientists.

Featured Publication

Regulation of T-cell receptor internalization by DENND1B in TH2 cells and allergic diseases.

Cell. 164:141-155, 2016.

Yang, CW, Hojer, CD, Zhou, M, Wu, X, Wuster, A, Lee, WP, Yaspan, BL and Chan, AC.

In this study, we demonstrate how a recently identified gene associated with the development of childhood asthma is due to a novel dysregulated mechanism that controls the internalization rate of the T-cell antigen receptor in TH2 cells following allergen challenge.