Dan Lu
Senior Principal Scientist Development Modeling & Simulation, Development Sciences
"I aim to deliver the right dose to the right patient by applying modeling and simulation approaches"
13
Years at Genentech
40
Publications at Genentech
I joined Genentech in March of 2009 after 2 years of work at Roche Palo Alto preclinical modeling and simulation group. Since joining Genentech, I have worked on both clinical pharmacology and modeling & simulation aspects to support drug development, mainly in the field of monoclonal antibodies and antibody drug conjugates for cancer treatment.
Featured Publication
Time-to-Event Analysis of Polatuzumab Vedotin-Induced Peripheral Neuropathy to Assist in the Comparison of Clinical Dosing Regimens.
CPT:PSP, CPT Pharmacometrics Syst Pharmacol. 2017 Jun;6(6):401-408.
Lu D, Gillespie WR, Girish S, Agarwal P, Li C, Hirata J, Chu YW, Kagedal M, Leon L, Maiya V, Jin JY.
My Focus
I am focusing on applying the advanced modeling and simulation approaches to support drug development.
Genentech Publications
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Michael Z. Liao; Dan Lu; Kagedal; Dale Miles; Divya Samineni; Stephanie N. Liu; Chunze Li
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Gengbo Liu; Dan Lu; James Lu
Pharmaceutical Research, ISSN: 1573904X 07248741
Dan Lu; Tong Lu; Rong Shi; Leonid Gibiansky; Priya Agarwal; Colby S. Shemesh; Randall Dere; Uzor Ogbu; Jamie Hirata; Pascal Chanu; Sandhya Girish; Jin Yan Jin; Chunze Li; Dale Miles
Leukemia and Lymphoma, ISSN: 10292403 10428194
Tong Lu; Leonid Gibiansky; Xiaobin Li; Chunze Li; Rong Shi; Priya Agarwal; Jamie Hirata; Dale Miles; Pascal Chanu; Sandhya Girish; Jin Yan Jin; Dan Lu
Journal of Clinical Pharmacology, ISSN: 15524604 00912700
Divya Samineni; Hao Ding; Fang Ma; Rong Shi; Dan Lu; Dale Miles; Jialin Mao; Chunze Li; Jin Jin; Matthew Wright; Sandhya Girish; Yuan Chen
Journal of Clinical Pharmacology, ISSN: 15524604 00912700
Chunze Li; Shang-Chiung Chen; Yuan Chen; Sandhya Girish; Matts Kaagedal; Dan Lu; Tong Lu; Divya Samineni; Jin Yan Jin
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Rong Shi; Tong Lu; Grace Ku; Hao Ding; Tomohisa Saito; Leonid Gibiansky; Priya Agarwal; Xiaobin Li; Jin Yan Jin; Sandhya Girish; Dale Miles; Chunze Li; Dan Lu
PLoS Computational Biology, ISSN: 15537358 1553734X
Jennifer L. Wilson; Dan Lu; Nick Corr; Aaron Fullerton; James Lu
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Colby S. Shemesh; Priya Agarwal; Tong Lu; Calvin Lee; Randall Dere; Xiaobin Li; Chunze Li; Jin Yan Jin; Sandhya Girish; Dale Miles; Dan Lu
Leukemia and Lymphoma, ISSN: 10292403 10428194
Rong Deng; Leonid Gibiansky; Tong Lu; Xiaobin Li; Dan Lu; Chunze Li; Sandhya Girish; Jue Wang; Michelle Boyer; Noopur Shankar; Kathryn Humphrey; Kevin J. Freise; Ahmed Hamed Salem; John F. Seymour; Kater; Dale Miles
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Dan Lu; Tong Lu; Leonid Gibiansky; Xiaobin Li; Chunze Li; Priya Agarwal; Colby S. Shemesh; Rong Shi; Randall Dere; Jamie Hirata; Dale Miles; Pascal Chanu; Sandhya Girish; Jin Yan Jin
mAbs, ISSN: 19420870 19420862
Chunze Li; Cindy Zhang; Zao Li; Divya Samineni; Dan Lu; Wang; Shang-Chiung Chen; Rong Zhang; Priya Agarwal; Bernard M. Fine; Sandhya Girish
Clinical Pharmacokinetics, ISSN: 11791926 03125963
Rong Deng; Leonid Gibiansky; Tong Lu; Priya Agarwal; Hao Ding; Xiaobin Li; Smita Kshirsagar; Dan Lu; Chunze Li; Sandhya Girish; Jue Wang; Michelle Boyer; Kathryn Humphrey; Kevin J. Freise; Ahmed Hamed Salem; John F. Seymour; Kater; Dale Miles
Clinical and Translational Science, ISSN: 17528062 17528054
Chunze Li; Cindy Zhang; Rong Deng; Douglas Leipold; Dongwei Li; Brandon Latifi; Yuying Gao; Crystal Zhang; Zao Li; Dale Miles; Shang-Chiung Chen; Divya Samineni; Wang; Priya Agarwal; Dan Lu; Saileta Prabhu; Sandhya Girish; Amrita Kamath
The Lancet Oncology, ISSN: 14745488 14702045
Herve Tilly; Morschhauser; Nancy L. Bartlett; Amitkumar Mehta; Gilles Salles; Corinne Haioun; Javier Munoz; Chen; Kathryn S. Kolibaba; Dan Lu; Mark Yan; Elicia M. Penuel; Jamie Hirata; Calvin Lee; Jeff P. Sharman
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Dan Lu; Chunze Li; Matthew Riggs; Daniel Polhamus; Jonathan French; Priya Agarwal; Shang-Chiung Chen; Shweta Vadhavkar; Patre; Alexander Strasak; Angelica Quartino; Jin Yan Jin; Sandhya Girish
The Lancet Haematology, ISSN: 23523026
Morschhauser; Ian W. Flinn; Ranjana H. Advani; Laurie H. Sehn; Catherine S. Diefenbach; Kathryn S. Kolibaba; Oliver W. Press; Gilles Salles; Herve Tilly; Chen; Sarit E. Assouline; Bruce D. Cheson; Dreyling; Anton Hagenbeek; Pier Luigi Zinzani; Surai Jones; Ji Cheng; Dan Lu; Elicia M. Penuel; Jamie Hirata; Michael Wenger; Yu-Waye Chu; Jeff P. Sharman
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Kagedal; Divya Samineni; Gillespie; Dan Lu; Bernard M. Fine; Sandhya Girish; Chunze Li; Jin Y. Jin
Journal of Pharmacokinetics and Pharmacodynamics, ISSN: 15738744 1567567X
Kagedal; Leonid Gibiansky; Jian Xu; Xin Wang; Divya Samineni; Shang-Chiung Chen; Dan Lu; Priya Agarwal; Wang; Ola M. Saad; Neelima Koppada; Bernard M. Fine; Jin Y. Jin; Sandhya Girish; Chunze Li
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Chunze Li; Wang; Shang-Chiung Chen; Russell D. Wada; Dan Lu; Xin Wang; Daniel Polhamus; Jonathan French; Shweta Vadhavkar; Alexander Strasak; Melanie Smitt; Amita Joshi; Meghna Samant; Angelica Quartino; Jin Y. Jin; Sandhya Girish
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Dan Lu; Gillespie; Sandhya Girish; Priya Agarwal; Chunze Li; Jamie Hirata; Yu-Waye Chu; Kagedal; Leon; Maiya; Jin Y. Jin
AAPS Journal, ISSN: 15507416
Rui Zhu; Dan Lu; Yu-Waye Chu; Akiko Chai; Michelle Green; Nancy Zhang; Jin Y. Jin
Clinical Cancer Research, ISSN: 15573265 10780432
Ranjana H. Advani; Lebovic; Chen; Mark Brunvand; Andre Goy; Julie E. Chang; Ephraim Hochberg; Sreeni Yalamanchili; Robert S. Kahn; Dan Lu; Priya Agarwal; Randall Dere; Hsin-Ju Hsieh; Surai Jones; Yu-Waye Chu; Bruce D. Cheson
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Dan Lu; Leonid Gibiansky; Priya Agarwal; Randall Dere; Chunze Li; Yu-Waye Chu; Jamie Hirata; Amita Joshi; Jin Y. Jin; Sandhya Girish
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Chunze Li; Wang; Dan Lu; Jin Y. Jin; Yuying Gao; Kiyoshi Matsunaga; Yuriko Igawa; Ihsan Nijem; Michael W. Lu; Alexander Strasak; Nataliya Chernyukhin; Sandhya Girish
Breast Cancer Research, ISSN: 1465542X 14655411
Ian E. Krop; Shanu Modi; Patricia M. LoRusso; Pegram; Ellie Guardino; Betsy Althaus; Dan Lu; Alexander Strasak; Anthony Elias
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Dan Lu; Tong Lu; Mark Stroh; Richard A. Graham; Priya Agarwal; Luna Musib; Chi-Chung Li; Bert L. Lum; Amita Joshi
Pharmaceutical Research, ISSN: 1573904X 07248741
Dan Lu; Jin Y. Jin; Sandhya Girish; Priya Agarwal; Dongwei Li; Saileta Prabhu; Randall Dere; Ola M. Saad; Denise Nazzal; Neelima Koppada; Ramanujan; Chee Ng
The Lancet Oncology, ISSN: 14745488 14702045
Palanca-Wessels; Myron S. Czuczman; Gilles Salles; Sarit E. Assouline; Laurie H. Sehn; Ian Flinn; Manish R. Patel; Randeep Sangha; Anton Hagenbeek; Ranjana H. Advani; Herve Tilly; Olivier Casasnovas; Oliver W. Press; Sreeni Yalamanchili; Robert S. Kahn; Randall Dere; Dan Lu; Surai Jones; Cheryl L. Jones; Yu-Waye Chu; Morschhauser
Clinical Pharmacokinetics, ISSN: 11791926 03125963
Yuan Chen; Divya Samineni; Sophie Mukadam; Harvey Wong; Shen; Dan Lu; Sandhya Girish; Cornelis E. Hop; Jin Y. Jin; Chunze Li
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Dan Lu; Sandhya Girish; Yuying Gao; Wang; Joo-Hee Yi; Ellie Guardino; Meghna Samant; Melody A. Cobleigh; Mothaffar F. Rimawi; Pier Franco Conte; Jin Y. Jin
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Dan Lu; Amita Joshi; Li; Nancy Zhang; Melanie Ren; Yuying Gao; Russell D. Wada; Jin Y. Jin
Clinical Pharmacokinetics, ISSN: 03125963 11791926
Dan Lu; Amita Joshi; Wang; Steve Olsen; Joo-Hee Yi; Ian E. Krop; Howard A. Burris; Sandhya Girish
Bioanalysis, ISSN: 17576180 17576199
Dan Lu; Srikumar Sahasranaman; Yi Zhang; Sandhya Girish
Current Drug Metabolism, ISSN: 13892002 18755453
Dan Lu; Howard A. Burris; Wang; E. Claire Dees; Javier Cortés; Amita Joshi; Manish Gupta; Joo-Hee Yi; Yu-Waye Chu; Ted Shih; Liang Fang; Sandhya Girish
Cancer Chemotherapy and Pharmacology, ISSN: 03445704 14320843
Sandhya Girish; Manish Gupta; Wang; Dan Lu; Ian E. Krop; Charles L. Vogel; Howard A. Burris; Patricia M. LoRusso; Joo-Hee Yi; Ola M. Saad; Barbara Tong; Yu-Waye Chu; Scott N. Holden; Amita Joshi
Cancer Chemotherapy and Pharmacology, ISSN: 03445704 14320843
Amrita Kamath; Dan Lu; Priyanka Gupta; Denise Jin; Hong Xiang; Anne Wong; Cecilia Leddy; Lisa Crocker; Gabriele Schaefer; Mark X. Sliwkowski; Lisa A. Damico
Cancer Chemotherapy and Pharmacology, ISSN: 03445704 14320843
Amrita Kamath; Dan Lu; Priyanka Gupta; Denise Jin; Yan Xin; Ann Brady; Jean-Philippe Stephan; Hao Li; Janet Y. Tien; Jing Qing; Lisa A. Damico
Clinical Pharmacokinetics, ISSN: 03125963 11791926
Shuang Bai; Karin Jorga; Yan Xin; Denise Jin; Zheng; Lisa A. Damico; Manish Gupta; Meina Tao Tang; David E. Allison; Dan Lu; Yi Zhang; Amita Joshi; Mark J. Dresser
Therapeutic Delivery, ISSN: 20415990 20416008
Saileta Prabhu; C. Andrew Boswell; Douglas Leipold; Leslie A. Khawli; Dongwei Li; Dan Lu; Frank-Peter Theil; Amita Joshi; Bert L. Lum
Education
- Ohio State University, Ph.D. – 2006