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Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 501 - 550 OF 15971 RESULTS

Entrectinib in ROS1-positive advanced non-small cell lung cancer: the phase 2/3 BFAST trial
Nature Medicine, ISSN: 1546170X 10788956
Solange Peters; Shirish M. Gadgeel; Tony Mok; Ernest Nadal; Saadettin Kilickap; Aurélie Swalduz; Jacques Cadranel; Shunichi Sugawara; Chao-Hua Chiu; Chong-Jen Yu; Mor Moskovitz; Tomohiro Tanaka; Rhea Nersesian; Sarah M. Shagan; Margaret Maclennan; Michael Mathisen; Vijay Bhagawati-Prasad; Cheick Diarra; Zoe June Assaf; Venice Archer; Rafal Dziadziuszko
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Accelerated drug-resistant variant discovery with an enhanced, scalable mutagenic base editor platform
Cell Reports,
Kristel Dorighi; Anqi Zhu; Jean-Philippe Fortin; Jerry Hung-Hao Lo; Jawahar Sudhamsu; Timothy J. Wendorff; Durinck; Marinella G. Callow; Scott A. Foster; Benjamin Haley
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CRISPR activation screens identify the SWI/SNF ATPases as suppressors of ferroptosis
Cell Reports,
Kamakoti P. Bhat; Jinchu Vijay; Caroline K. Vilas; Jyoti Asundi; Jun Zou; Ted Lau; Xiaoyu Cai; Musaddeque Ahmed; Michal Kabza; Julie Weng; Jean-Philippe Fortin; Aaron T. L. Lun; Durinck; Marc Hafner; Michael Costa; Xin Ye
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Development of a First-Generation Stereocontrolled Manufacturing Process of TRPA1 Inhibitor GDC-6599
Organic Process Research and Development, ISSN: 10836160
Allen Y. Hong; Katarzyna A. Piechowicz; Jacob C. Timmerman; Haiming Zhang; Carmela Molinaro; Francis Gosselin
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Optimization of a Novel DEL Hit That Binds in the Cbl-b SH2 Domain and Blocks Substrate Binding
ACS Medicinal Chemistry Letters,
Jun Liang; Michael J. Lambrecht; Teresita L. Arenzana; Samuel Aubert-Nicol; Linda Bao; Broccatelli; Jianping Cai; Celine Eidenschenk; Christine Everett; Thomas Garner; Felix Gruber; Pouyan Haghshenas; Malcolm P. Huestis; Peter L. Hsu; Ponien Kou; Araz Jakalian; Larouche-Gauthier; Jean-Philippe Leclerc; Dennis H. Leung; Aaron Martin; Jeremy Murray; Madeleine S. Prangley; Sascha Rutz; Satoko Kakiuchi-Kiyota; Alexander Lee Satz; Nicholas J. Skelton; Micah Steffek; Daniel Stoffler; Jawahar Sudhamsu; Sophia Tan; Jian Wang; Shouliang Wang; Qiuyue Wang; Timothy J. Wendorff; Moreno Wichert; Arun Yadav; Christine Yu; Xiaojing Wang
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Publisher Correction: Anti-TIGIT antibody improves PD-L1 blockade through myeloid and Treg cells(Nature, 10.1038/s41586-024-07121-9)
Nature, ISSN: 00280836
Xiangnan Guan; Ruozhen Hu; Yoonha Choi; Shyam Srivats; Barzin Y. Nabet; John Silva; Lisa M McGinnis; Robert Hendricks; Katherine Nutsch; Karl L. Banta; Ellen Duong; Alexis D. Dunkle; Patrick Chang; Chia-Jung Han; Stephanie Mittman; Nandini Molden; Pallavi Daggumati; Wendy Connolly; Melissa L. Johnson; Rodriguez-Abreu; Byoung Chul Cho; Antoine Italiano; Ignacio Gil-Bazo; Enriqueta Felip; Ira Mellman; Sanjeev Mariathasan; David S. Shames; Raymond D. Meng; Eugene Y. Chiang; Robert J. Johnston; Namrata S. Patil
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Potency-Enhanced Peptidomimetic VHL Ligands with Improved Oral Bioavailability
Journal of Medicinal Chemistry, ISSN: 00222623
Hao Wu; Jeremy Murray; Noriko Ishisoko; Alexandra Frommlet; Gauri Deshmukh; Antonio G. DiPasquale; Melinda M. Mulvihill; Donglu Zhang; John Quinn; Robert A. Blake; Wayne J. Fairbrother; Jakob Fuhrmann
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Context-Specific Stress Causes Compartmentalized SARM1 Activation and Local Degeneration in Cortical Neurons
Journal of Neuroscience, ISSN: 02706474
Flora I. Hinz; Carmela Louise M. Villegas; Jasmine Roberts; Heming Yao; Shreya Gaddam; Anton Delwig; Samantha A. Green; Craig Fredrickson; Max Adrian; Raymond Asuncion; Tommy K. Cheung; Margaret Hayne; David Hackos; Christopher M. Rose; David Richmond; Casper C Hoogenraad
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Umpolung Flow Chemistry for the Synthesis of a 3-Oxo-3H-spiro[benzofuran-2,4′-piperidine] Building Block
Journal of Organic Chemistry, ISSN: 00223263
Matthew M. Pompeo; Sean M. Kelly; Frederic St-Jean; Thomas M. Bass; Derek M. Dalton; Daniel Zell; Chong Han; Lauren E. Sirois; Francis Gosselin
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The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity
Cancer immunology research, ISSN: 23266066
Junghyun Lim; Ryan Rodriguez; Katherine Williams; John Silva; Alan G. Gutierrez; Paul Tyler; Faezzah Baharom; Tao Sun; Eva Lin; Scott E. Martin; Brandon D. Kayser; Robert J. Johnston; Ira Mellman; Lélia Delamarre; Nathaniel West; Sören Müller; Yan Qu; Klaus D. Heger
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Challenges and gaps in immunosafety evaluation of therapeutics: An IQ DruSafe survey
Regulatory Toxicology and Pharmacology, ISSN: 10960295 02732300
Mark Collinge; Haley Neff-LaFord; Surekha Akella; Birgit Fogal; Kathryn Fraser; Jacob Jabbour; Kirsty Harper; Curtis Maier; Laurent Malherbe; Nikki Marshall; Gautham K. Rao; Kavita Raman; Hollie Skaggs; Felix Weber; Claudette L. Fuller
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Accelerated Predictive Stability Study of a Pediatric Drug Product for a Supplemental New Drug Application
AAPS PharmSciTech,
Viktoria Rakers; Jin Wang; Dawen Kou
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Clinical Value of Timely Targeted Therapy for Patients With Advanced Non–Small Cell Lung Cancer With Actionable Driver Oncogenes
Oncologist, ISSN: 10837159
Thomas Stricker; Neha Jain; Esprit Ma; Elaine B. Yu; Rongrong Wang; Robert Schuldt; Richard Price; Szado; Jesse Sussell; Sarika Ogale; Victor Lin; Arrowsmith; Slater; Daniel Vaena; Harry Staszewski; Bruno Fang; Lasika Seneviratne; Davey B Daniel
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A randomized, double-blind study of zinpentraxin alfa in patients with myelofibrosis who were previously treated with or ineligible for ruxolitinib: stage 2 of a phase II trial
Haematologica, ISSN: 03906078
Srdan Verstovsek; Moshe Talpaz; Martha Wadleigh; Alessandro Isidori; Peter te Boekhorst; Michael Savona; Prithviraj Bose; Olga Pozdnyakova; Ruben Mesa; Tarec C. El-Galaly; Jennifer O’Sullivan; Katia Gamel; Higgins; Sudhakar Katakam; Boyan Todorov; Kerstin Trunzer; Claire N. Harrison
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Impact of P-gp inhibition on systemic exposure of pralsetinib and dosing considerations
Clinical and Translational Science, ISSN: 17528054
Julia Suchomel; Priya Agarwal; Doreen Anders; Kevin Hughes; Yang Tang; Rucha Sane; Astrid Scalori; Sunil Sharma; Sravanthi Cheeti
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Optimizing Messenger RNA Analysis Using Ultra-Wide Pore Size Exclusion Chromatography Columns
International Journal of Molecular Sciences, ISSN: 16616596
Valentina D'Atri; Honorine Lardeux; Alexandre Goyon; Mateusz Imiołek; Szabolcs Fekete; Matthew A Lauber; Kelly Zhang; Davy Guillarme
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HER2 Gene Expression Levels Are Predictive and Prognostic in Patients with Metastatic Colorectal Cancer Enrolled in CALGB/SWOG 80405
Journal of Clinical Oncology, ISSN: 0732183X
Francesca Battaglin; Fang-Shu Ou; Xueping Qu; Hochster; Donna Niedzwiecki; Richard M. Goldberg; Robert J. Mayer; Karam Ashouri; Tyler J. Zemla; Charles D. Blanke; Alan P. Venook; Omar Kabbarah; Heinz-Josef Lenz; Federico Innocenti
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Quantitative analysis of bone marrow fibrosis highlights heterogeneity in myelofibrosis and augments histological assessment: An Insight from a phase II clinical study of zinpentraxin alfa
HemaSphere,
Hosuk Ryou; Korsuk Sirinukunwattana; Ruby Wood; Alan Aberdeen; Jens Rittscher; Olga Weinberg; Robert P. Hasserjian; Olga Pozdnyakova; Franklin V. Peale Jr.; Higgins; Pontus Lundberg; Kerstin Trunzer; Claire N. Harrison; Daniel Royston
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Population pharmacokinetics and CD20 binding dynamics for mosunetuzumab in relapsed/refractory B-cell non-Hodgkin lymphoma
Clinical and Translational Science, ISSN: 17528054
Brendan C. Bender; Chi-Chung Li; Mathilde Marchand; Turner; Feifei Li; Shweta Vadhavkar; Wang; Rong Deng; James Lu; Jin Jin; Chunze Li; Shen Yin; Michael C. Wei; Pascal Chanu
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Aqueous humour interleukin-6 and vision outcomes with anti-vascular endothelial growth factor therapy
Eye,
Yasir J. Sepah; Diana V. Do; Marina Mesquida; Bann-Mo Day; Steven Blotner; Rubbia Afridi; Muhammad Sohail Halim; Kyu Hong; Eric Wakshull; Sascha Fauser; Ivaylo Stoilov; Quan Dong Nguyen
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Systematic decoding of cis gene regulation defines context-dependent control of the multi-gene costimulatory receptor locus in human T cells
Nature Genetics, ISSN: 15461718 10614036
Cody T. Mowery; Jacob W. Freimer; Zeyu Chen; Salvador Casaní-Galdón; Jennifer M. Umhoefer; Maya M. Arce; Ketrin Gjoni; Bence Dániel; Katalin D. Sándor; Benjamin G. Gowen; Vinh Q. Nguyen; Dimitre R. Simeonov; Christian M. Garrido; Gemma L. Curie; Ralf L.J. Schmidt; Zachary B. Steinhart; Ansuman T. Satpathy; Katherine S. Pollard; Jacob E. Corn; Bradley E. Bernstein; Chun Jimmie Ye; Alexander Marson
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Implementation of a Three-Way Comparability Assessment for a Bioanalytical Anti-Drug Antibody Method
AAPS Journal,
Rosanna S. Kwok; Ihsan Nijem; Ann Brady; Robert Hendricks
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Adaptive and Innate Immunity Are Key Drivers of Age at Onset of Multiple Sclerosis
Neurology: Genetics,
Elina Misicka; Yunfeng Huang; Stephanie J. Loomis; Nilanjana Sadhu; Fisher; Arie R. Gafson; Heiko Runz; Ellen Tsai; Xiaoming Jia; Ann E. Herman; Paola G. Bronson; Tushar Bhangale; Farren B. Briggs
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Molecular underpinnings of dedifferentiation and aggressiveness in chromophobe renal cell carcinoma
JCI insight,
Payal Kapur; Hua Zhong; Daniel Le; Ratna Mukhopadhyay; Jeffrey Miyata; Deyssy Carrillo; Dinesh Rakheja; Satwik Rajaram; Durinck; Zora Modrusan; James Brugarolas
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The inactivation of tolC sensitizes Escherichia coli to perturbations in lipopolysaccharide transport
iScience,
Shawna Zhu; Mary Kate Alexander; Telmo O. Paiva; Kenneth Rachwalski; Anh Miu; Yiming Xu; Vishal A. Verma; Mike Reichelt; Yves F. Dufrêne; Eric D. Brown; Georgina Cox
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Using the Dynamic Well-Stirred Model to Extrapolate Hepatic Clearance of Organic Anion-Transporting Polypeptide Transporter Substrates without Assuming Albumin-Mediated Hepatic Drug Uptake
Drug Metabolism and Disposition,
Zhengyin Yan; Li Ma; Nicky Hwang; Julie Huang; Jane R. Kenny; Cornelis E. Hop
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N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation
Immunity, ISSN: 10747613
Alexander D. Gitlin; Maltzman; Yuzuka Kanno; Klaus D. Heger; Rohit Reja; Alexander F Schubert; Linsey J. Wierciszewski; Homer Pantua; Sharookh B. Kapadia; Seth F. Harris; Webster; Kim Newton; Vishva M. Dixit
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Correction to: FOXO1 is a master regulator of memory programming in CAR T cells (Nature, (2024), 629, 8010, (211-218), 10.1038/s41586-024-07300-8)
Nature, ISSN: 14764687 00280836
Alexander E. Doan; Katherine P. Mueller; Andy Y. Chen; Geoffrey T. Rouin; Yingshi Chen; Bence Dániel; John E. Lattin; Martina Markovska; Brett Mozarsky; Jose Arias-Umana; Robert Y. Hapke; Inyoung Jung; Alice Wang; Peng Xu; Dorota Danuta Klysz; Gabrielle N. Zuern; Malek Mansoor Bashti; Patrick J. Quinn; Zhuang Miao; Katalin D. Sándor; Wenxi Zhang; Gregory M. Chen; Faith Ryu; Meghan T. Logun; Junior W. Hall; Kai Tan; Stephan A. Grupp; Susan E. McClory; Caleb A. Lareau; Joseph A. Fraietta; Elena Sotillo; Ansuman T. Satpathy; Crystal Lee MacKall; Evan W. Weber
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FOXO1 is a master regulator of memory programming in CAR T cells
Nature, ISSN: 14764687 00280836
Alexander E. Doan; Katherine P. Mueller; Andy Y. Chen; Geoffrey T. Rouin; Yingshi Chen; Bence Dániel; John E. Lattin; Martina Markovska; Brett Mozarsky; Jose Arias-Umana; Robert Y. Hapke; Inyoung Jung; Alice Wang; Peng Xu; Dorota Danuta Klysz; Gabrielle N. Zuern; Malek Mansoor Bashti; Patrick J. Quinn; Zhuang Miao; Katalin D. Sándor; Wenxi Zhang; Gregory M. Chen; Faith Ryu; Meghan T. Logun; Junior W. Hall; Kai Tan; Stephan A. Grupp; Susan E. McClory; Caleb A. Lareau; Joseph A. Fraietta; Elena Sotillo; Ansuman T. Satpathy; Crystal Lee MacKall; Evan W. Weber
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Human Pharmacokinetic and CYP3A DDI Prediction of GDC-2394 using PBPK Modeling and Biomarker Assessment
Drug Metabolism and Disposition, ISSN: 00909556
Jesse Yu; Fei Tang; Fang Ma; Susan C. Wong; Jing Wang; Justin Ly; Liuxi Chen; Jialin Mao
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An Integrated Hepatocyte Stability Assay for Simultaneous Metabolic Stability Assessment and Metabolite Profiling
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Christian Leung; Joyce Liu; Katherine Cunico; Kevin Johnson; Zhengyin Yan; Jingwei Cai
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A Minimal PBPK/PD Model with Expansion-Enhanced Target-Mediated Drug Disposition to Support a First-in-Human Clinical Study Design for a FLT3L-Fc Molecule
Pharmaceutics,
Iraj Hosseini; Brett Fleisher; Jennifer A. Getz; Jérémie Decalf; Mandy Kwong; Meric A. Ovacik; Travis W. Bainbridge; Christine Moussion; Gautham K. Rao; Kapil Gadkar; Amrita Kamath; Ramanujan
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Alternative Splicing Is a Major Factor Shaping Transcriptome Diversity in Mild and Severe Chronic Obstructive Pulmonary Disease
American Journal of Respiratory Cell and Molecular Biology,
Dmitry Khalenkow; Brandsma; Timens; David F. Choy; Michele A. Grimbaldeston; Carrie M. Rosenberger; Dirk-Jan Slebos; Kerstjens; Alen Faiz; Gerard H. Koppelman; Nawijn; van den Berge; Victor Guryev
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Deep Learning Approaches for Detecting of Nascent Geographic Atrophy in Age-Related Macular Degeneration
Ophthalmology Science,
Heming Yao; Zhichao Wu; Simon S. Gao; Robyn H. Guymer; Verena Steffen; Hao Chen; Mohsen Hejrati; Miao Zhang
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Rationale and Design of VOYAGER: Long-term Outcomes of Faricimab and Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration and Diabetic Macular Edema in Clinical Practice
Ophthalmology Science, ISSN: 26669145
Robyn Heather Guymer; Clare C. Bailey; Voraporn Chaikitmongkol; Usha Chakravarthy; Varun S. Chaudhary; Robert Patrick Finger; Roberto Gallego-Pinazo; Adrian Koh Hock Chuan; Susuxnu Ishida; Monica Lóvestam-Adrian; Mariacristina Parravano; José Domingo Luna; Steffen Schmitz-Valckenberg; Veeral S. Sheth; Éric H. Souied; Gloria C. Chi; Frank Gilberg; Carl G.O. Glittenberg; Stefan Scheidl; Monica Bengus
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Graph-pMHC: graph neural network approach to MHC class II peptide presentation and antibody immunogenicity
Briefings in bioinformatics, ISSN: 14675463
William John Thrift; Jason Perera; Sivan Cohen; Nicolas Lounsbury; Hem R. Gurung; Christopher M. Rose; Jieming Chen; Suchit Jhunjhunwala; Kai Liu
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Patient Experience Survey of Anti-Vascular Endothelial Growth Factor Treatment for Neovascular Age-Related Macular Degeneration and Diabetic Macular Edema
Ophthalmic Research, ISSN: 14230259 00303747
Nancy M. Holekamp; Brittany Gentile; Audrey Giocanti-Aurégan; Alfredo García-Layana; Tunde Peto; Francesco Viola; Peter J. Kertes; Mirela Mirt; Aachal Kotecha; Jérémy Lambert; Hannah B. Lewis; Gloria C. Chi
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Six-year follow-up and subgroup analyses of a phase 2 trial of venetoclax for del(17p) chronic lymphocytic leukemia
Blood advances, ISSN: 24739529
Stephan Stilgenbauer; Eugen Tausch; Andrew W. Roberts; Matthew S. Davids; Barbara Eichhorst; Michael Hallek; Hillmen; Christof Schneider; Johannes Schetelig; Sebastian Böttcher; Kater; Yanwen Jiang; Michelle Boyer; Relja Popovic; Majd T. Ghanim; Michael Moran; Wendy J. Sinai; Xifeng Wang; Nabanita Mukherjee; Brenda Chyla; William G. Wierda; John F. Seymour
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TRBC1-targeting antibody–drug conjugates for the treatment of T cell cancers
Nature, ISSN: 14764687 00280836
Tushar D. Nichakawade; Jiaxin Ge; Brian J. Mog; Bum Seok Lee; Alex Pearlman; Michael S. Hwang; Sarah R. DiNapoli; Nicolas Wyhs; Nikita Marcou; Stephanie Glavaris; Maximilian F. Konig; Sandra B. Gabelli; Evangeline Watson; Cole Sterling; Nina D. Wagner-Johnston; Sima Rozati; Lode J. Swinnen; Ephraim Fuchs; Drew M. Pardoll; Kathy Gabrielson; Nickolas Papadopoulos; Chetan Bettegowda; Kenneth W. Kinzler; Shibin Zhou; Surojit Sur; Bert Vogelstein; Suman Paul
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Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
Molecular Cell, ISSN: 10974164 10972765
Jerry Li; Nicholas Purser; Joanna Liwocha; Daniel C. Scott; Holly A. Byers; Barbara Steigenberger; Spencer Hill; Ishita Tripathi-Giesgen; Trent Hinkle; Fynn M. Hansen; J. Rajan Prabu; Senthil K. Radhakrishnan; Donald S. Kirkpatrick; Kurt M. Reichermeier; Brenda A. Schulman; Gary Kleiger
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Genome-wide characterization of circulating metabolic biomarkers
Nature, ISSN: 14764687 00280836
Minna Karjalainen; Savita Karthikeyan; Clare Oliver-Williams; Eeva Sliz; Elias Allara; Wing Tung Fung; Praveen Surendran; Weihua Zhang; Pekka Jousilahti; Kati Kristiansson; Veikko Salomaa; Matt Goodwin; David A. Hughes; Mike Boehnke; Lilian Fernandes Silva; Xianyong Yin; Anubha Mahajan; Matt J. Neville; Natalie van Zuydam; Renée de Mutsert; Ruifang Li-Gao; Dennis Mook-Kanamori; Ayse Demirkan; Jun Liu; Raymond Noordam; Stella Trompet; Zhengming Chen; Christiana Kartsonaki; Liming Li; Kuang Lin; Fiona A. Hagenbeek; Jouke-Jan Hottenga; René Pool; M Arfan Ikram; Joyce B.J. Van Meurs; Toomas Haller; Yuri Milaneschi; Mika Kähönen; Pashupati P. Mishra; Peter K Joshi; Erin Macdonald-Dunlop; Massimo Mangino; Jonas Zierer; Ilhan E. Acar; Carel Hoyng; Yara T. E. Lechanteur; Lude Franke; Alexander Kurilshikov; Alexandra Zhernakova; Marian Beekman; Erik van den Akker; Ivana Kolcic; Ozren Polasek; Igor Rudan; Christian Gieger; Melanie Waldenberger; Folkert W Asselbergs; Caroline Hayward; Jingyuan Fu; Anneke I. den Hollander; Cristina Menni; Tim D. Spector; James F. Wilson; Terho Lehtimäki; Olli T. Raitakari; Brenda Penninx; Tõnu Esko; Robin G. Walters; J Wouter Jukema; Naveed Sattar; Mohsen Ghanbari; Ko Willems van Dijk; Fredrik Karpe; Mark I. McCarthy; Markku Laakso; Marjo-Riitta Jarvelin; Nicholas J. Timpson; Markus Perola; Jaspal S Kooner; John C Chambers; Cornelia M. van Duijn; P. Eline Slagboom; Dorret I. Boomsma; John Danesh; Mika Ala-Korpela; Adam S. Butterworth; Johannes Kettunen
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Clinical pharmacology strategies to accelerate the development of polatuzumab vedotin and summary of key findings
Advanced Drug Delivery Reviews, ISSN: 0169409X
Michael Z. Liao; Dan Lu; Tong Lu; Leonid Gibiansky; Rong Deng; Divya Samineni; Randall Dere; Andy Lin; Jamie Hirata; Shen; Donglu Zhang; Dongwei Li; Chunze Li; Dale Miles
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Platinum ineligibility and survival outcomes in patients with advanced urothelial carcinoma receiving first-line treatment
Journal of the National Cancer Institute, ISSN: 00278874
Shilpa Gupta; Alexander Andreev-Drakhlin; Otto Fajardo; Marcella Fassò; Jorge A. Garcia; Christopher Wee; Carsten Schröder
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Comparative genomics incorporating translocation renal cell carcinoma mouse model reveals molecular mechanisms of tumorigenesis
Journal of Clinical Investigation, ISSN: 00219738
Gopinath Prakasam; Akhilesh Mishra; Alana Christie; Jeffrey Miyata; Deyssy Carrillo; Vanina Toffessi Tcheuyap; Hui Ye; Quyen N. Do; Yunguan Wang; Oscar Reig Torras; Ramesh Butti; Hua Zhong; Jeffrey Gagan; Kevin B. Jones; Thomas J. Carroll; Zora Modrusan; Durinck; Mai-Carmen Requena-Komuro; Noelle S. Williams; Ivan Pedrosa; Tao Wang; Dinesh Rakheja; Payal Kapur; James Brugarolas
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2023 White Paper on Recent Issues in Bioanalysis: ISR for ADA Assays, the Rise of dPCR vs qPCR, International Reference Standards for Vaccine Assays, Anti-AAV TAb Post-Dose Assessment, NanoString Validation, ELISpot as Gold Standard (Part 3 - Recommendations on Gene Therapy, Cell Therapy, Vaccines Immunogenicity & Technologies; Biotherapeutics Immunogenicity & Risk Assessment; ADA/NAb Assay/Reporting Harmonization)
Bioanalysis,
Johanna Mora; Rachel Palmer; Leslie Wagner; Bonnie Wu; Michael A. Partridge; Meena; Ivo Sonderegger; John Smeraglia; Nicoletta Bivi; Naveen Dakappagari; Sandra Diebold; Fabio Garofolo; Grimaldi; Warren Kalina; John Kamerud; Sumit Kar; Jean-Claude Marshall; Christian Mayer; Andrew Melton; Keith D. Merdek; Katrina Nolan; Serge Picard; Weiping Shao; Jessica Seitzer; Yoichi Tanaka; Omar Tounekti; Adam Vigil; Karl Walravens; Joshua Xu; Weifeng Xu; Yuanxin Xu; Lin Yang; Liang Zhu; Verthelyi; Robert J Kubiak; Kelly Coble; Swati Gupta; Mohsen Rajabi Abhari; Susan Richards; Yuan Song; Martin Ullmann; Boris Calderon; Isabelle Cludts; George R. Gunn; Shalini Gupta; Akiko Ishii-Watabe; Mohanraj Manangeeswaran; Kimberly Maxfield; Fred McCush; Christine O'Day; Kate Peng; Johann Poetzl; Michele Rasamoelisolo; Ola M. Saad; Kara Scheibner; Sophie Shubow; Sam Song; Seth Thacker
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Differential depletion of GluN2A induces heterogeneous schizophrenia-related phenotypes in mice
EBioMedicine,
Yi Lu; Longyu Mu; Justin Elstrott; Chaoying Fu; Cailu Sun; Tonghui Su; Xiaofan Ma; Jia Yan; Hong Jiang; Jesse E. Hanson; Yang Geng; Yelin Chen
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AviTrap: A novel solution to achieve complete biotinylation
PLoS ONE,
Cheng Lu; Jack Bevers; Tulika Tyagi; Hao To; May Lin; Shu Ti; Gerry Nakamura; WeiYu Lin; Yongmei Chen; Yan Wu; Hong Li; Jiansheng Wu; Feng Wang
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Exploring the Impact of Hepatic Impairment on Pralsetinib Pharmacokinetics
Pharmaceutics,
Kit Wun Kathy Cheung; Yang Tang; Doreen Anders; Barata; Astrid Scalori; Priya Agarwal; Rucha Sane; Sravanthi Cheeti
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Atezolizumab plus bevacizumab in advanced Merkel cell carcinoma: A prospective study
Oral Oncology, ISSN: 13688375
L. Guimaraes de Sousa; Liu; Bhosale; Altan; Darbonne; Katja Schulze; Shannon Dervin; Cindy Yun; Armeen Mahvash; Anuj Verma; Andrew Futreal; Swati Gite; E. Parra Cuentas; Cho; Ignacio I. Wistuba; Yao; Scott E. Woodman; Daniel M. Halperin; Ferrarotto
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Simulation-based evaluation of personalized dosing approaches for anti-FGFR/KLB bispecific antibody fazpilodemab
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Kenta Yoshida; Victor Poon; Ajit Dash; Rebecca Kunder; Leslie Wei Chinn; Matts Kågedal
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