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Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

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International Journal of Pharmaceutics, ISSN: 18733476 03785173
Joseph A. Ferrar; Ben Sellers; Connie Chan; Dennis Leung
Cell Chemical Biology, ISSN: 24519448 24519456
Foteini Tzakoniati; Hui Xu; Tianbo Li; Natalie Garcia; Christine Kugel; Jian Payandeh; Chris Koth; Edward W. Tate
The complement C5 inhibitor crovalimab in paroxysmal nocturnal hemoglobinuria
Blood,
Alexander Röth; Jun-Ichi Nishimura; Zsolt Nagy; Julia Gaàl-Weisinger; Jens Panse; Sung-Soo Yoon; Miklos Egyed; Satoshi Ichikawa; Yoshikazu Ito; Jin Seok Kim; Haruhiko Ninomiya; Hubert Schrezenmeier; Simona Sica; Kensuke Usuki; Flore Sicre de Fontbrune; Juliette Soret; Alexandre Sostelly; James Higginson; Andreas Dieckmann; Brittany Gentile; Judith Anzures-Cabrera; Kenji Shinomiya; Gregor Jordan; Marta Biedzka-Sarek; Barbara Klughammer; Angelika Jahreis; Christoph Bucher; Régis Peffault de Latour
GCNT1-mediated O-glycosylation of the sialomucin CD43 is a sensitive indicator of notch signaling in activated T cells
Journal of Immunology, ISSN: 00221767
Eric Perkey; Dave Maurice De Sousa; Leolene Carrington; Jooho Chung; Alexander Dils; David Granadier; Ute Koch; Freddy Radtke; Burkhard Ludewig; Bruce R. Blazar; Chris Siebel; Todd V. Brennan; Jeffrey Nolz; Nathalie Labrecque; Ivan Maillard
A First-in-Human Phase I Study to Evaluate the ERK1/2 Inhibitor GDC-0994 in Patients with Advanced Solid Tumors
Clinical Cancer Research, ISSN: 10780432
Andrea Varga; Jean-Charles Soria; Antoine Hollebecque; Patricia M. LoRusso; Bendell; Shih-Min A. Huang; Marie-Claire Wagle; Kwame Okrah; Lichuan Liu; Elaine Murray; Sandra Sanabria; Tagen; Hatem Dokainish; Lars Mueller; Howard A. Burris
Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab
Science, ISSN: 00368075
Lionel Rouge; Nancy Chiang; Micah Steffek; Christine Kugel; Tristan I. Croll; Christine Tam; Alberto Estevez; Chris Arthur; Chris Koth; Claudio Ciferri; Edward Kraft; Jian Payandeh; Gerry Nakamura; JT Koerber; Alexis Rohou
Nature, ISSN: 14764687 00280836
Thomas Wu; Shravan Madireddi; Patricia De Almeida; Romain Banchereau; Ying-Jiun J. Chen; Avantika S. Chitre; Eugene Chiang; Hina Iftikhar; William E. O’Gorman; Amelia Au-Yeung; Chikara Takahashi; Leonard Goldstein; Chungkee Poon; Shilpa Keerthivasan; Denise De Almeida Nagata; Xiangnan Du; Hyang-Mi Lee; Karl L. Banta; Sanjeev Mariathasan; Meghna Das Thakur; Mahrukh Huseni; Marcus Ballinger; Ivette Estay; Patrick Caplazi; Zora Modrusan; Lelia Delamarre; Ira Mellman; Richard Bourgon; Jane Grogan
Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy
Science Translational Medicine,
Maud Mayoux; Andreas Roller; Vesna Pulko; Stefano Sammicheli; Stanford Chen; Eva Sum; Christian Jost; Marieke F. Fransen; Regula B. Buser; Marcin Kowanetz; Karolin Rommel; Ines Matos; Sara Colombetti; Anton Belousov; Vaios Karanikas; Ferry Ossendorp; Priti Hegde; Daniel S. Chen; Pablo Umaña; Mario Perro; Christian Klein; Wei Xu
Cell Stem Cell, ISSN: 18759777 19345909
Neil McCarthy; Elisa Manieri; Elaine E. Storm; Assieh Saadatpour; Adrienne M. Luoma; Varun N. Kapoor; Shariq Madha; Liam T. Gaynor; Christian Cox; Shilpa Keerthivasan; Kai Wucherpfennig; Guo-Cheng Yuan; Frederic De Sauvage; Shannon Turley; Ramesh A. Shivdasani
Molecular Cell, ISSN: 10974164 10972765
Lilian Phu; Christopher M. Rose; Joy S. Tea; Christopher E. Wall; Erik Verschueren; Tommy K Cheung; Don Kirkpatrick; Baris Bingol
Molecular Cell, ISSN: 10974164 10972765
Kurt M. Reichermeier; Ronny Straube; Justin M. Reitsma; Michael J. Sweredoski; Christopher M. Rose; Annie Moradian; Willem den Besten; Trent Hinkle; Erik Verschueren; Georg Petzold; Nicolas H. Thomä; Ingrid Wertz; Raymond J. Deshaies; Don Kirkpatrick
Structure, ISSN: 18784186 09692126
David Migl; Marc Kschonsak; Chris Arthur; Yadana Khin; Stephen C. Harrison; Claudio Ciferri; Yoana Dimitrova
Journal of Experimental Medicine, ISSN: 15409538 00221007
Mary Keir; Tangsheng Yi; Timothy T. Lu; Nico Ghilardi
Journal of Rheumatology, ISSN: 0315162X
Charles G. Peterfy; Joel M. Kremer; William F. Rigby; Nora G. Singer; Christine Birchwood; Darcy Gill; William Reiss; Jinglan Pei; Margaret Michalska
PDA Journal of Pharmaceutical Science and Technology, ISSN: 19482124
Robert Ovadia; Philippe Lam; Vassia Tegoulia; Yuh-Fun Maa
PDA Journal of Pharmaceutical Science and Technology, ISSN: 19482124
Paul Wu; Taymar Hartman; Louise Almond; Jennitte Stevens; John Thrift; Juhi Ojha; Christina Alves; David Shaw; Mike Laird; Robyn Emmins; Yuan Zhu; Ren Liu; Zhimei Du; Rolf Koehler; Thomas Jostock; Karin Anderson; Chris Campbell; Howard Clarke
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Po-Chang Chiang; Karthik Nagapudi; Michael J. Dolton; Jia Liu
Journal of Nuclear Medicine, ISSN: 15355667
Eric Berg; Herman Gill; Jan Marik; Annie Ogasawara; Simon P. Williams; Guus van Dongen; Daniëlle Vugts; Simon R. Cherry; Alice F. Tarantal
Cold Spring Harbor Perspectives in Medicine, ISSN: 21571422
Kim Newton
AAPS Journal, ISSN: 15507416
Herman Gill; Richard Seipert; Vincent M. Carroll; Alexandra Gouasmat; Jian Yin; Annie Ogasawara; Isabella de Jong; Minh Michael Phan; Xiangdan Wang; Jihong Yang; Ohad Ilovich; Jan Marik; Simon P. Williams
Cell Death and Disease, ISSN: 20414889
Loretta Dorstyn; Denis Tvorogov; Shiva Malek; Nirmal Robinson
Proceedings of the IEEE Southwest Symposium on Image Analysis and Interpretation,
Omid Bazgir; Kai Barck; Rick Carano; Robby Weimer; Luke Xie
Pharmaceutical Research, ISSN: 1573904X 07248741
Phyllis Chan; Jiajie Yu; Leslie Chinn; Marita Prohn; Jan Huisman; Brett Matzuka; William D. Hanley; Katie Tuckwell; Angelica Quartino
Clinical Cancer Research, ISSN: 10780432
Melody A. Cobleigh; Denise A. Yardley; Adam Brufsky; Hope S. Rugo; Sandra M. Swain; Peter A. Kaufman; Debasish Tripathy; Sara A. Hurvitz; O'Shaughnessy; Ginny Mason; Vince Antao; Haocheng Li; Laura Chu; Mohammad Jahanzeb
American Journal of Respiratory and Critical Care Medicine, ISSN: 15354970 1073449X
Richard J. Allen; Beatriz Guillen-Guio; Justin M. Oldham; Shwu-Fan Ma; Amy Stockwell; Megan L. Paynton; Luke M. Kraven; Ma'en Obeidat; Xuan Li; Michael Ng; Rebecca Braybrooke; Maria Molina-Molina; Brian D. Hobbs; Rachel K. Putman; Phuwanat Sakornsakolpat; Helen L. Booth; William A. Fahy; Simon P. Hart; Mike R. Hill; Nik Hirani; Richard B. Hubbard; Robin J. McAnulty; Ann B. Millar; Vidyia Navaratnam; Eunice Oballa; Helen Parfrey; Gauri Saini; Moira K.B. Whyte; Yingze Zhang; Naftali Kaminski; Ayodeji Adegunsoye; Mary E. Strek; Margaret Neighbors; X Rebecca Sheng; Gunnar Gudmundsson; Vilmundur Gudnason; Hiroto Hatabu; David J. Lederer; Ani W Manichaikul; John Newell; George T. O'Connor; Victor E. Ortega; Hanfei Xu; Tasha E. Fingerlin; Yohan Bossé; Ke Hao; Philippe Joubert; David C. Nickle; Don D. Sin; Timens; Dominic Furniss; Andrew P. Morris; Krina T. Zondervan; Ian P. Hall; Ian Sayers; Martin Tobin; Toby; Michael H. Cho; Gary M. Hunninghake; David A. Schwartz; Brian Yaspan; Philip L. Molyneaux; Carlos Flore
Science, ISSN: 10959203 00368075
Nikit Kumar; Chris Arthur; Claudio Ciferri; Marissa Matsumoto
Journal of Neuroscience, ISSN: 15292401 02706474
Bill Meilandt; Hai Ngu; Alvin Gogineni; Guita Lalehzadeh; Seung-Hye Lee; Karpagam Srinivasan; Jose Imperio; Tiffany Wu; Martin Weber; Agatha J. Kruse; Kimberly Stark; Pamela Chan; Mandy Kwong; Zora Modrusan; Brad Friedman; Justin Elstrott; Oded Foreman; Amy Easton; Morgan Sheng; X David V. Hansen
ACS Chemical Biology, ISSN: 15548937 15548929
Dan Burdick; Nicholas Skelton; Mark Ultsch; Maureen Beresini; Charles Eigenbrot; Wei Li; Yingnan Zhang; Huy Quoc Nguyen; Monica Beltran; John Quinn; Daniel Kirchhofer
Immunity, ISSN: 10974180 10747613
Yi Zhou; Mingjian Fei; Gu Zhang; Wei-Ching Liang; WeiYu Lin; Yan Wu; Robert Piskol; John Brady; Erin McNamara; Haochu Huang; Juan Zhang; Jaehak Oh; Jaina M. Patel; Diana Jakubiak; Jeff Lau; Beth Blackwood; Daniel D. Bravo; Yongchang Shi; Jianyong Wang; Hong-Ming Hu; Wyne P. Lee; Rajiv Jesudason; Dewakar Sangaraju; Zora Modrusan; Keith Anderson; Soren Warming; Meron Roose-Girma; Minhong Yan
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Peter Dragovich; Pragya Adhikari; Robert Blake; Nicole Blaquiere; Jinhua Chen; Yun-Xing Cheng; Willem den Besten; Jinping Han; Steven J. Hartman; Jintang He; Mingtao He; Ellen Rei Ingalla; Amrita Kamath; Tracy Kleinheinz; Tommy Lai; Douglas Leipold; Chun Sing Li; Qi Liu; Jiawei Lu; Ying Lu; Fanwei Meng; Lingyao Meng; Carl Ng; Kaishan Peng; Gail D. Lewis Phillips; Thomas Pillow; Rebecca K. Rowntree; Jack D. Sadowsky; Deepak Sampath; Leanna Staben; Steven Staben; John Wai; Kunpeng Wan; Xinxin Wang; Binqing Wei; Ingrid Wertz; Jianfeng Xin; Keyang Xu; Hui Yao; Richard Zang; Donglu Zhang; Hao Zhou; Yongxin Zhao
Respiratory Research, ISSN: 1465993X 14659921
Colin H. Holtze; Elizabeth A. Freiheit; Susan L. Limb; John L. Stauffer; Karina Raimundo; Wayne T. Pan; Kevin R. Flaherty; Hyun J. Kim
Heterogeneity of Satellite Cells Implicates DELTA1/NOTCH2 Signaling in Self-Renewal
Cell Reports,
Valeria Yartseva; Leonard Goldstein; Julia Rodman; Lance Kates; Mark Z. Chen; Jasmine Chen; Oded Foreman; Chris Siebel; Zora Modrusan; Andrew S. Peterson; Ana Jovičić
Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma
Journal of Clinical Investigation,
Emilie Bousquet Mur; Sara Bernardo; Laura Papon; Maicol Mancini; Eric Fabbrizio; Marion Goussard; Irene Ferrer; Anais Giry; Xavier Quantin; Jean-Louis Pujol; Olivier Calvayrac; Herwig P. Moll; Yaël Glasson; Nelly Pirot; Andrei Turtoi; Marta Cañamero; Kwok-Kin Wong; Yarden; Emilio Casanova; Jean-Charles Soria; Jacques Colinge; Chris Siebel; Julien Mazieres; Gilles Favre; Luis Paz-Ares; Antonio Maraver
Nature Structural and Molecular Biology, ISSN: 15459985 15459993
Annette M. Vogl; Lilian Phu; Raquel Becerra; Sebastian A. Giusti; Erik Verschueren; Trent Hinkle; Martín D. Bordenave; Max Adrian; Amy Heidersbach; Patricio Yankilevich; Fernando D. Stefani; Wolfgang Wurst; Casper C Hoogenraad; Don Kirkpatrick; Damian Refojo; Morgan Sheng
Cancer Discovery, ISSN: 21598290
Claudia Dominguez; Sören Müller; Shilpa Keerthivasan; Hartmut Koeppen; Jeffrey Hung; Sarah Gierke; Beatrice Breart; Oded Foreman; Travis Bainbridge; Alessandra Castiglioni; Yasin Senbabaoglu; Zora Modrusan; Yuxin Liang; Melissa Junttila; Christiaan Klijn; Richard Bourgon; Shannon Turley
Clinical Cancer Research, ISSN: 15573265 10780432
Katherine E. Hutchinson; Susan E. Yost; Ching-Wei Chang; Radia Johnson; Adrian R. Carr; Paul R. McAdam; Daniel L Halligan; Chun-Chieh Chang; Daniel Schmolze; Jackson Liang; Yuan Yuan
Brain, ISSN: 14602156
Kaj Blennow; Chun Chen; Claudia Cicognola; Kristin Wildsmith; Paul T. Manser; Sandra M Sanabria Bohorquez; Zhentao Zhang; Boer Xie; Junmin Peng; Oskar Hansson; Hlin Kvartsberg; Erik Portelius; Henrik Zetterberg; Tammaryn Lashley; Gunnar Brinkmalm; Geoffrey A. Kerchner; Robby Weimer; Keqiang Ye; Kina Höglund
Nature Medicine, ISSN: 1546170X 10788956
Katherine S Ruth; Felix R Day; Jessica Tyrrell; Deborah J Thompson; Andrew R Wood; Anubha Mahajan; Robin N Beaumont; Laura Wittemans; Susan Martin; Alexander S. Busch; A. Mesut Erzurumluoglu; Benjamin Hollis; Tracy A. O’Mara; Mark McCarthy; Claudia Langenberg; Douglas F. Easton; Nicholas J Wareham; Stephen Burgess; Anna Murray; Ken K. Ong; Timothy M. Frayling; John R. Perry
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Aaron G. Bart; Ryan Takahashi; Gina Wang; Emily E. Scott
Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1–2 trials
The Lancet Oncology, ISSN: 14702045
Robert C Doebele; Alexander Drilon; Luis Paz-Ares; Siena; Alice T. Shaw; Anna F Farago; Collin M Blakely; Takashi Seto; Byung Chul Cho; Diego Tosi; Benjamin Besse; Sant P Chawla; Lyudmila Bazhenova; John C Krauss; Young K Chae; Minal Barve; Ignacio Garrido-Laguna; Stephen V. Liu; Paul Conkling; Thomas John; Marwan Fakih; Darren Sigal; Herbert H Loong; Gary L Buchschacher; Pilar Garrido; Jorge Nieva; Conor Steuer; Tobias R Overbeck; Daniel W. Bowles; Elizabeth Fox; Todd Riehl; Edna Chow-Maneval; Brian Simmons; Na Cui; Ann Johnson; Susan Eng; Tim Wilson; George Demetri
Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1–2 trials
The Lancet Oncology, ISSN: 14702045
Alexander Drilon; Siena; Rafal Dziadziuszko; Fabrice Barlesi; Matthew G Krebs; Alice T. Shaw; Filippo de Braud; Christian Rolfo; Myung-Ju Ahn; Jurgen Wolf; Takashi Seto; Byoung Chul Cho; Manish R. Patel; Chao-Hua Chiu; Tom John; Koichi Goto; Karapetis; Hendrick-Tobias Arkenau; Sang-We Kim; Yuichiro Ohe; Yu-Chung Li; Young K Chae; Christine H Chung; Gregory A Otterson; Haruyasu Murakami; Chia-Chi Lin; Daniel S W Tan; Hans Prenen; Todd Riehl; Edna Chow-Maneval; Brian Simmons; Na Cui; Ann Johnson; Susan Eng; Tim Wilson; Robert C Doebele
International standards for the analysis of quality-of-life and patient-reported outcome endpoints in cancer randomised controlled trials: recommendations of the SISAQOL Consortium
The Lancet Oncology, ISSN: 14702045
Corneel Coens; Madeline Pe; Amylou Dueck; Jeff A. Sloan; Ethan Basch; Melanie Calvert; Alicyn Campbell; Charles S. Cleeland; Kim Cocks; Laurence Collette; Nancy Devlin; Lien Dorme; Hans-Henning Flechtner; Carolyn C. Gotay; Ingolf Griebsch; Mogens Groenvold; Madeleine King; Paul G Kluetz; Michael Koller; Daniel C Malone; Francesca Martinelli; Sandra A Mitchell; Jammbe Musoro; Daniel O'Connor; Kathy Oliver; Elisabeth Piault-Louis; Martine Piccart; Chantal Quinten; Jaap C Reijneveld; Christoph Schürmann; Ashley Wilder Smith; Katherine M Soltys; Martin J. B. Taphoorn; Galina Velikova; Andrew Bottomley
Pharmaceutical Research, ISSN: 1573904X 07248741
Phyllis Chan; Jiajie Yu; Leslie Chinn; Marita Prohn; Jan Huisman; Brett Matzuka; William D. Hanley; Katie Tuckwell; Angelica Quartino
Pharmacology Research and Perspectives, ISSN: 20521707
Khaled Sarsour; Senam Beckley-Kartey; Simone Melega; Adefowope Odueyungbo; Petra Kirchner; Natasha Khalife; Joanne Bangs
Genome-wide analysis of differential gene expression and splicing in excitatory neurons and interneuron subtypes
Journal of Neuroscience, ISSN: 02706474
Melanie Huntley; Karpagam Srinivasan; Brad Friedman; Tzu-Ming Wang; Ada X. Yee; Yuanyuan Wang; Josh Kaminker; Morgan Sheng; David Hansen; Jesse E. Hanson
Cell Reports, ISSN: 22111247
Luz D. Orozco; Hsu-Hsin Chen; Christian Cox; Ken Katschke; Rommel Arceo; Carmina Espiritu; Patrick Caplazi; Sarajane Saturnio Nghiem; Jasmine Chen; Zora Modrusan; Amy Stockwell; Leonard Goldstein; Christine Clarke; Tushar Bhangale; Brian Yaspan; Marion Jeanne; Michael Townsend; Menno van Lookeren Campagne; Jason Hackney
Alzheimer's Research and Therapy, ISSN: 17589193
Yoshida; Anita Moein; Tobias Bittner; Ostrowitzki; Helen Lin; Lee Honigberg; Jin Y. Jin; Angelica Quartino
Analytical Chemistry, ISSN: 15206882 00032700
Hae-Min Park; Valerie J. Winton; Jared J. Drader; Sheri Manalili Wheeler; Greg Lazar; Neil L Kelleher; Yichin Liu; John C. Tran; Philip D. Compton
Clinical Cancer Research, ISSN: 15573265 10780432
David E. Gerber; Jeffrey R. Infante; Michael S. Gordon; Sarah B. Goldberg; Miguel Martín; Enriqueta Felip; Maria Martinez Garcia; Joan H. Schiller; David Spigel; Julie Cordova; Valerie Westcott; Wang; David Shames; YJ Choi; Robert S. Kahn; Randy Dere; Divya Samineni; Jian Xu; Kedan Lin; Katie Wood; Stephanie Joo; Lemahieu; Schuth; Vaze; Daniel Maslyar; Eric Humke; Howard A. Burris
Cell Reports, ISSN: 22111247
Jesse E. Hanson; Keran Ma; Justin Elstrott; Martin Weber; Sandrine Saillet; Abdullah S. Khan; Jeffrey Simms; Benjamin Liu; Thomas A. Kim; Gui-Qiu Yu; Yelin Chen; Tzu-Ming Wang; Zhiyu Jiang; Bianca Liederer; Gauri Deshmukh; Hilda Solanoy; Connie Chan; Ben Sellers; Matthew Volgraf; Jacob Schwarz; David Hackos; Robby Weimer; Morgan Sheng; T. Michael Gill; Kimberly Scearce-Levie; Jorge J. Palop