Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 251 - 300 OF 11836 RESULTS

Clinical Rheumatology, ISSN: 14349949 07703198
Vivian P. Bykerk; Ostor; José Alvaro-Gracia; Karel Pavelka; José Andrés Román Ivorra; Michael T. Nurmohamed; Yves Luder; Paris N. M. Sidiropoulos; Jenny Devenport; Jean Sibilia
Clinical Cancer Research, ISSN: 15573265 10780432
Aparna R. Parikh; Fa-Chyi Lee; Linda Yau; Han Koh; James Knost; Edith P. Mitchell; Ivan Bosanac; Nicholas Choong; Frank Scappaticci; Christoph Mancao; Heinz-Josef Lenz
Pharmacokinetics of trastuzumab emtansine (T-DM1) as a single agent or in combination with pertuzumab in HER2-positive breast cancer patients with recurrent or locally advanced metastatic breast cancer
Cancer Chemotherapy and Pharmacology, ISSN: 03445704
Dan Lu; Chunze Li; Matthew Riggs; Daniel Polhamus; Jonathan French; Priya Agarwal; Shang-Chiung Chen; Shweta Vadhavkar; Patre; Alexander Strasak; Angelica Quartino; Jin Yan Jin; Sandhya Girish
Angewandte Chemie - International Edition, ISSN: 15213773 14337851
Seung Wook Kim; Tabitha T. Schempp; Jason Zbieg; Craig Stivala; Michael J. Krische
RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases
Cell Death and Differentiation, ISSN: 13509047
Snahel Patel; Webster; Eugene Varfolomeev; Youngsu Kwon; Jason Cheng; Juan Zhang; Debbie Dugger; Kate Wickliffe; Maltzman; Swathi Sujatha-Bhaskar; Pawan Bir Kohli; Sreema Ramaswamy; Gauri Deshmukh; Bianca Liederer; Rina Fong; Gregory L. Hamilton; Patrick Lupardus; Patrick Caplazi; Wyne P. Lee; Menno van Lookeren Campagne; Adam Johnson; Brent McKenzie; Melissa Junttila; Kim Newton; Domagoj Vucic
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Steven J. McKerrall; Teresa Nguyen; Kwong Wah Lai; Philippe Bergeron; Lunbin Deng; Antonio DiPasquale; Jae Chang; Jun Chen; Tania Chernov-Rogan; David Hackos; Jonathan M. Maher; Dan Ortwine; Jodie Pang; Jian Payandeh; Will Proctor; Shannon Shields; Jennifer Vogt; Pengfei Ji; Wenfeng Liu; Elisa Ballini; Lilia Schumann; Glauco Tarozzo; Girish Bankar; Sultan Chowdhury; Abid Hasan; Johnson; Kuldip Khakh; Sophia Lin; Charles J. Cohen; Christoph Dehnhardt; Brian Safina; Dan Sutherlin
Tetrahedron, ISSN: 14645416 00404020
Chong Han; Sean Kelly; Theresa Cravillion; Scott Savage; Tina Nguyen; Francis Gosselin
Ophthalmology, ISSN: 15494713 01616420
Peter A. Campochiaro; Dennis Marcus; Carl C. Awh; Carl D. Regillo; Anthony Adamis; Vladimir Bantseev; Yawen Chiang; Jason Ehrlich; Signe Erickson; William D. Hanley; Joshua Horvath; Katie F. Maass; Natasha Singh; Fan Tang; Giulio Barteselli
trackr: A Framework for Enhancing Discoverability and Reproducibility of Data Visualizations and Other Artifacts in R
Journal of Computational and Graphical Statistics, ISSN: 10618600
Gabriel Becker; Sara E. Moore; Michael Lawrence
Methods in Molecular Biology, ISSN: 10643745
Amelia Au-Yeung; Chikara Takahashi; Rod Mathews; William E. O'Gorman
Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients
Nature Medicine, ISSN: 10788956
Ryan J. Sullivan; Omid Hamid; Rene Gonzalez; Jeffery R. Infante; Manish R. Patel; F. Stephen Hodi; Karl Lewis; Hussein Tawbi; Genevive Hernandez; Matthew Wongchenko; YiMeng Chang; Louise Roberts; Marcus Ballinger; Yibing Yan; Edward Cha; Patrick Hwu
Correction: First-in-human phase 1 study of the BTK inhibitor GDC-0853 in relapsed or refractory B-cell NHL and CLL (Oncotarget(2018) 9 (13023 -13035) DOI: 10.18632/oncotarget.24310)
Oncotarget,
John C. Byrd; Stephen Smith; Nina D. Wagner-Johnston; Jeff P. Sharman; Andy I. Chen; Ranjana H. Advani; Bradley Augustson; Paula Marlton; Renee Commerford; Kwame Okrah; Lichuan Liu; Elaine Murray; Elicia Penuel; Ashley F. Ward; Ian Flinn
Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors
Journal of Medicinal Chemistry, ISSN: 00222623
Callie Bryan; Joy Drobnick; Alberto Gobbi; Aleksandr Kolesnikov; Yongsheng Chen; Naomi S. Rajapaksa; Chudi Ndubaku; Jianwen Feng; Willy Chang; Ross Francis; Christine Yu; Edna Choo; Kevin DeMent; Yingqing Ran; Le An; Claire Emson; Zhiyu Huang; Swathi Sujatha-Bhaskar; Hans Brightbill; Antonio DiPasquale; Jonathan M. Maher; John Wai; Brent McKenzie; Patrick Lupardus; Ali Zarrin; James Kiefer
Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site
Journal of Biological Chemistry, ISSN: 00219258
Shu Xu; Jashim Uddin; Surajit Banerjee; Kelsey Duggan; Joel Musee; James Kiefer; Kebreab Ghebreselasie; Carol A. Rouzer; Lawrence J. Marnett
Palladium-catalyzed enantioselective decarboxylative allylic alkylation of fully substituted: N -acyl indole-derived enol carbonates
Chemical Science, ISSN: 20416520
Eric J. Alexy; Tyler J. Fulton; Haiming Zhang; Brian M. Stoltz
Palladium-catalyzed α,β-dehydrogenation of acyclic ester equivalents promoted by a novel electron deficient phosphinooxazoline ligand
Tetrahedron, ISSN: 00404020
Tyler J. Fulton; Brenda Wu; Eric J. Alexy; Haiming Zhang; Brian M. Stoltz
Pharmacokinetic and exposure–response analysis of pertuzumab in patients with HER2-positive metastatic gastric or gastroesophageal junction cancer
Cancer Chemotherapy and Pharmacology, ISSN: 03445704
Whitney P. Kirschbrown; Wang; Ihsan Nijem; Atsushi Ohtsu; Paulo M. Hoff; Manish A. Shah; Lin Shen; Yoon-Koo Kang; Maria Alsina; Sandhya Girish; Amit Garg
Prediction of Human Pharmacokinetics of Antibody–Drug Conjugates From Nonclinical Data
Clinical and Translational Science, ISSN: 17528054
Chunze Li; Cindy Zhang; Rong Deng; Douglas Leipold; Dongwei Li; Brandon Latifi; Yuying Gao; Crystal Zhang; Zao Li; Dale Miles; Shang-Chiung Chen; Divya Samineni; Wang; Priya Agarwal; Dan Lu; Saileta Prabhu; Sandhya Girish; Amrita Kamath
Probing interaction of lipid-modified wnt protein and its receptors by ELISA
Methods in Molecular Biology, ISSN: 10643745
Aaron Nile; Rami Hannoush
Safety, clinical activity and biomarker assessments of atezolizumab from a Phase I study in advanced/recurrent ovarian and uterine cancers
Gynecologic Oncology, ISSN: 00908258
Joyce F. Liu; Michael S. Gordon; Jennifer Veneris; Fadi S. Braiteh; Ani Balmanoukian; Joseph Paul Eder; Ana Oaknin; Hamilton; Wang; Indrani Sarkar; Luciana Molinero; Marcella Fasso; Carol E. O'Hear; Yvonne G. Lin; Leisha A. Emens
Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel NaV1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers
Clinical Drug Investigation, ISSN: 11732563
Michael E. Rothenberg; Tagen; Jae H. Chang; Janel Boyce-Rustay; Michel Friesenhahn; David Hackos; Avis Hains; Dan Sutherlin; Michael Ward; William Cho
The safety evaluation of long-acting ocular delivery systems
Drug Discovery Today, ISSN: 13596446
Evan Thackaberry; Florence Lorget; Cindy A. Farman; Vladimir Bantseev
Unequal absorption of radiolabeled and nonradiolabeled drug from the oral dose leads to incorrect estimates of drug absorption and circulating metabolites in a mass balance study
Drug Metabolism Letters, ISSN: 18723128
Ryan Takahashi; Jae H. Chang; Jodie Pang; Xiaorong Liang; Shuguang Ma
A potent and effective suicidal listeria vaccine platform
Infection and Immunity, ISSN: 00199567
William G. Hanson; Erin L. Benanti; Edward E. Lemmens; Weiqun Liu; Justin Skoble; Meredith L. Leong; Chris S. Rae; Marcella Fasso; Dirk Brockstedt; Chen Chen; Daniel A. Portnoy; Thomas W. Dubensky; Peter Lauer
An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development
Nature Immunology, ISSN: 15292908
Prachi Bagadia; Xiao Huang; Tian-Tian Liu; Vivek Durai; Gary E. Grajales-Reyes; Maximilian Nitschke; Zora Modrusan; Jeffrey M. Granja; Ansuman T. Satpathy; Carlos G. Briseño; Marco Gargaro; Arifumi Iwata; Sunkyung Kim; Howard Y. Chang; Andrey S. Shaw; Theresa L. Murphy; Kenneth M. Murphy
CHAPTER 11: Duocarmycin-PBD Dimers as Antibody-Drug Conjugate (ADC) Payloads
RSC Drug Discovery Series, ISSN: 20413203
Thomas Pillow; Moana Tercel
Cell Reports, ISSN: 22111247
Tiffany Wu; Borislav Dejanovic; Vineela Gandham; Alvin Gogineni; Rose Edmonds; Stephen Schauer; Karpagam Srinivasan; Melanie Huntley; Yuanyuan Wang; Tzu-Ming Wang; Maj Hedehus; Kai Barck; Maya Stark; Hai Ngu; Oded Foreman; Bill Meilandt; Justin Elstrott; Michael C. Chang; David Hansen; Rick Carano; Morgan Sheng; Jesse Hanson
Design and Evaluation of Highly Selective Human Immunoproteasome Inhibitors Reveal a Compensatory Process That Preserves Immune Cell Viability
Journal of Medicinal Chemistry, ISSN: 00222623
Ena Ladi; Christine Everett; Craig Stivala; Blake Daniels; Matthew Durk; Seth Harris; Malcolm Huestis; Hans Purkey; Steven Staben; Martin Augustin; Michael Blaesse; Stefan Steinbacher; Celine Eidenschenk; Rajita Pappu; Mike Siu
Impact of depth of response on survival in patients treated with cobimetinib ± vemurafenib: pooled analysis of BRIM-2, BRIM-3, BRIM-7 and coBRIM
British Journal of Cancer, ISSN: 00070920
Karl Lewis; James Larkin; Antoni Ribas; Keith Flaherty; Grant A. McArthur; Paolo A. Ascierto; Brigitte Dréno; Yibing Yan; Matthew Wongchenko; Edward McKenna; Qian Zhu; Yong Mun; Axel Hauschild
Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes
Cell Reports,
Myles J. Lewis; Michael R. Barnes; Blighe; Katriona Goldmann; Sharmila Rana; Jason Hackney; Nandhini Ramamoorthi; Christopher R. John; David S. Watson; Sarah Kummerfeld; Rebecca Hands; Sudeh Riahi; Vidalba Rocher-Ros; Felice Rivellese; Frances Humby; Stephen Kelly; Michele Bombardieri; Nora Ng; Maria Dicicco; Désirée Van Der Heijde; Robert Landewé; Annette H. M. Van Der Helm-van Mil; Alberto Cauli; McInnes; Christopher D. Buckley; Ernest Choy; Taylor; Michael Townsend; Costantino Pitzalis
The Lancet Oncology, ISSN: 14745488 14702045
Saura; Dominik Hlauschek; Oliveira; Zardavas; Jallitsch-Halper; Lorena de la Peña; Nuciforo; Alberto Ballestrero; Dubsky; Janine M Lombard; Peter Vuylsteke; Carlos A Castaneda; Colleoni; Giuliano Santos Borges; Eva Ciruelos; Monica Fornier; Katalin Boer; Aditya Bardia; Tim Wilson; Thomas J. Stout; Jerry Hsu; Yi Shi; Martine Piccart; Michael Gnant; José Baselga; Evandro de Azambuja
Investigational New Drugs, ISSN: 15730646 01676997
Shahneen Sandhu; Catriona McNeil; Patricia M. LoRusso; Manish R. Patel; Omar Kabbarah; Chunze Li; Sandra Sanabria; W. Michael Flanagan; Ru-Fang Yeh; Flavia Brunstein; Denise Nazzal; Rodney Hicks; Lemahieu; Raymond Meng; Omid Hamid; Jeffery R. Infante
Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging
JCI insight,
Denise P. Muñoz; Steven M. Yannone; Anneleen Daemen; Yu Sun; Funda Vakar-Lopez; Misako Kawahara; Adam M. Freund; Francis Rodier; Jennifer D. Wu; Pierre-Yves Desprez; David H. Raulet; Peter S. Nelson; Laura J. van’t Veer; Judith Campisi; Jean-Philippe Coppé
Toward a Consensus on Applying Quantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper
Clinical Pharmacology and Therapeutics, ISSN: 00099236
Bhagwat Prasad; Brahim Achour; Per Artursson; Marcel Hop; Yurong Lai; Philip C. Smith; Jill Barber; Jacek R. Wisniewski; Spellman; Yasuo Uchida; Michael A. Zientek; Jashvant D. Unadkat; Amin Rostami-Hodjegan
Respiration, ISSN: 14230356 00257931
Stéphane Jouneau; Anne-Sophie Gamez; Julie Traclet; Hilario Nunes; Sylvain Marchand-Adam; Romain Kessler; Dominique Israël-Biet; Raphael Borie; Indiana Strombom; Astrid Scalori; Bruno Crestani; Dominique Valeyre; Vincent Cottin
Biochimie, ISSN: 61831638 03009084
Andrew Ah Young; S. Y. Lin; Gerhardy; Menno van Lookeren Campagne; Daniel Kirchhofer
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Po-Chang Chiang; Karthik Nagapudi; Jia Liu; James Crawford; Jason Zbieg; Emile Plise; Yuzhong Deng
Nature Immunology, ISSN: 15292916 15292908
Christian Neumann; Jonas Blume; Urmi Roy; Peggy P. Teh; Ajithkumar Vasanthakumar; Alexander Beller; Yang Liao; Frederik Heinrich; Teresita L. Arenzana; Jason Hackney; Celine Eidenschenk; Eric J. C. Gálvez; Christina Stehle; Gitta A. Heinz; Patrick Maschmeyer; Tom Sidwell; Yifang Hu; Derk Amsen; Chiara Romagnani; Hyun-Dong Chang; Andrey Kruglov; Mir-Farzin Mashreghi; Wei Shi; Till Strowig; Sascha Rutz; Axel Kallies; Alexander Scheffold
Thorax, ISSN: 14683296 00406376
John Busby; Cecile Holweg; Akiko Chai; Peter Bradding; Fang Cai; Rekha Chaudhuri; Adel Mansur; James Lordan; John Matthews; Andrew Menzies-Gow; Robert Niven; Tracy Staton; Liam G Heaney
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Kai Zheng; Yan Chen; John Wang; Laura Zheng; Matthew Hutchinson; Josefine Persson; Junyan Ji
JAMA Oncology, ISSN: 23742445 23742437
Sylvia Adams; Luciana Molinero
Oncologist, ISSN: 1549490X 10837159
Carolina Reyes; Nicole M. Engel-Nitz; Stacey Dacosta Byfield; Arliene Mangalindan; Sarika Ogale; Tim Bancroft; Amy Anderson; May Chen; Matthew Matasar
Oncologist, ISSN: 1549490X 10837159
Carolina Reyes; Nicole M. Engel-Nitz; Stacey Dacosta Byfield; Arliene Mangalindan; Sarika Ogale; Tim Bancroft; Amy Anderson; May Chen; Matthew Matasar
Protein and Peptide Letters, ISSN: 18755305 09298665
Natalie K. Garcia; Galahad Deperalta; Aaron T. Wecksler
Journal of Immunology, ISSN: 15506606 00221767
Vladimir Ramirez Carrozzi; Neko Ota; Arivazhagan Sambandam; Kit Wong; Jason Hackney; Nadia Martinez-Martin; Wenjun Ouyang; Rajita Pappu
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Mark Zak; Emily Hanan; Patrick Lupardus; David G. Brown; Colin Robinson; Mike Siu; Joe Lyssikatos; Anthony Romero; Guiling Zhao; Terry Kellar II; Rohan Mendonca; Nicholas C. Ray; Simon Goodacre; Peter H. Crackett; Neville J. McLean; Christopher A. Hurley; Po-Wai Yuen; Yun-Xing Cheng; Xiongcai Liu; Marya Liimatta; Pawan Bir Kohli; Jim Nonomiya; Gary Salmon; Gerry Buckley; Julia Lloyd; Paul Gibbons; Nico Ghilardi; Jane Kenny; Adam Johnson
Clinical and Translational Science, ISSN: 17528062 17528054
Faith Stevison; Mika Kosaka; Jane Kenny; Susan Wong; Cathryn Hogarth; John K. Amory; Nina Isoherranen
Xenobiotica, ISSN: 13665928 00498254
Timothy W. Chow; Matthew Wright; Marcel Hop; Harvey Wong
European Journal of Medical Genetics, ISSN: 18780849 17697212
Babylakshmi Muthusamy; Thong Tom Nguyen; Aravind K. Bandari; Salah Basheer; Lakshmi Dhevi N. Selvan; Deepshikha Chandel; Jesna Manoj; Srimonta Gayen; Somasekar Seshagiri; Satish Chandra Girimaji; Akhilesh Pandey
Imaging, Genetic, and Demographic Factors Associated with Conversion to Neovascular Age-Related Macular Degeneration: Secondary Analysis of a Randomized Clinical Trial
JAMA Ophthalmology, ISSN: 21686165
Joelle A. Hallak; Luis De Sisternes; Aaron Osborne; Brian Yaspan; Daniel L. Rubin; Theodore Leng