Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 1051 - 1100 OF 15796 RESULTS

January 1, 2023

Prognostic value of severe acute respiratory syndrome coronavirus-2 viral load and antibodies in patients hospitalized with COVID-19

Clinical and Translational Science, ISSN: 17528062 17528054

Rebecca N. Bauer; Anastasia Teterina; Haridha Shivram; Jacqueline McBride; Carrie M. Rosenberger; Fang Cai; Min Bao; Larry Tsai; Oliver Gordon; Ivan T. Lee; Jeffrey J. Wallin; Danielle Porter; Kavita Juneja; Gregory Camus; Ivan O. Rosas; Steffen Wildum

January 1, 2023

Astegolimab or Efmarodocokin Alfa in Patients with Severe COVID-19 Pneumonia: A Randomized, Phase 2 Trial∗

Critical Care Medicine, ISSN: 15300293 00903493

Michael Waters; James A. McKinnell; Andre C. Kalil; Greg S. Martin; Timothy G. Buchman; Wiebke Theess; Xiaoying Yang; Annemarie N. Lekkerkerker; Tracy Staton; Carrie M. Rosenberger; Rajita Pappu; Yehong Wang; Wenhui Zhang; Logan Brooks; Dorothy Cheung; Joshua Galanter; Hubert Chen; Divya Mohan; Melicent Peck

January 1, 2023

Publisher Correction: Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial (Nature Medicine, (2019), 25, 11, (1706-1714), 10.1038/s41591-019-0628-7)

Nature Medicine, ISSN: 1546170X 10788956

Thomas Powles; Mark Kockx; Alejo Rodriguez-Vida; Ignacio Durán; Simon J. Crabb; Michiel S Van Der Heijden; Bernadett Szabados; Albert Font Pous; Gwenaëlle Gravis; Urbano Anido Herranz; Andrew Protheroe; Alain Ravaud; Denis Maillet; Maria Jose Mendez; Cristina Suarez; Mark Linch; Aaron Prendergast; Pieter-Jan van Dam; Diana Stanoeva; Sofie Daelemans; Sanjeev Mariathasan; Joy S. Tea; Kelly Mousa; Romain Banchereau; Daniel Castellano

January 1, 2023

Exploring the Use of a Kinetic pH Calculation to Correct the ACAT Model with a Single Stomach Compartment Setting: Impact of Stomach Setting on Food Effect Prediction for Basic Compounds

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Po-Chang Chiang; Michael J. Dolton; Karthik Nagapudi; Jia Liu

January 1, 2023

Mass spectrometry-based multi-attribute method in protein therapeutics product quality monitoring and quality control

mAbs, ISSN: 19420870 19420862

Feng Yang; Jennifer Zhang; Alexander Buettner; Eva Vosika; Monica Sadek; Zhiqi Hao; Dietmar Reusch; Maximiliane Koenig; Wayman Chan; Anja Bathke; Hilary Pallat; Victor Lundin; Kepert; Patrick Bulau; Galahad Deperalta; Christopher Yu; Richard L Beardsley; Tura Camilli; Reed J. Harris; Stults

January 1, 2023

Combining regulated and constitutive protein expression significantly boosts protein expression by increasing productivity without affecting CHO cell growth

Biotechnology Progress, ISSN: 15206033 87567938

Cynthia Lam; Joe Carver; Domingos Ng; Dejin Zhan; Danming Tang; Thara Kandamkalam; Snedecor; Gavin Barnard; Amy Shen; Shahram Misaghi

January 1, 2023

Shared learning from a physiologically based pharmacokinetic modeling strategy for human pharmacokinetics prediction through retrospective analysis of Genentech compounds

Biopharmaceutics and Drug Disposition, ISSN: 1099081X 01422782

Jialin Mao; Fang Ma; Jesse Yu; Tom De Bruyn; Miaoran Ning; Christine M. Bowman; Yuan Chen

January 1, 2023

Overall survival with first-line atezolizumab in combination with vemurafenib and cobimetinib in BRAFV600 mutation-positive advanced melanoma (IMspire150): second interim analysis of a multicentre, randomised, phase 3 study

The Lancet Oncology, ISSN: 14745488 14702045

Paolo A. Ascierto; Daniil Stroyakovskiy; Helen Gogas; Caroline Robert; Karl Lewis; Svetlana Protsenko; Rodrigo P Pereira; Thomas Eigentler; Piotr Rutkowski; Lev Demidov; Natalia Zhukova; Jacob Schachter; Yibing Yan; Ivor Caro; Christian Hertig; Cloris Xue; Lieke Kusters; Grant A McArthur; Ralf Gutzmer

January 1, 2023

Dose escalation randomised study of efmarodocokin alfa in healthy volunteers and patients with ulcerative colitis

Gut, ISSN: 14683288 00175749

Frank Wagner; John C. Mansfield; Annemarie N. Lekkerkerker; Yehong Wang; Mary E. Keir; Ajit Dash; Brandon Butcher; Brandon Harder; Luz D. Orozco; Jordan S. Mar; Hao Chen; Michael E. Rothenberg

January 1, 2023

From Logic-Respecting Efficacy Estimands to Logic-Ensuring Analysis Principle for Time-to-Event Endpoint in Randomized Clinical Trials with Subgroups

Statistics in Biopharmaceutical Research, ISSN: 19466315

Yi Liu; Miao Yang; Siyoen Kil; Jiang Li; Shoubhik Mondal; Yue Shentu; Hong Tian; Liwei Wang; Godwin Yung

January 1, 2023

ER+, HER2− advanced breast cancer treated with taselisib and fulvestrant: genomic landscape and associated clinical outcomes

Molecular Oncology, ISSN: 18780261 15747891

Jessica W. Chen; William Jacot; Javier Cortés; Ian E. Krop; Susan Dent; Nadia Harbeck; De Laurentiis; Diéras; Young-Hyuck Im; Thomas J. Stout; Frauke Schimmoller; Heidi Savage; Katherine E. Hutchinson; Wilson

January 1, 2023

Activation of the PERK branch of the unfolded protein response during production reduces specific productivity in CHO cells via downregulation of PDGFRa and IRE1a signaling

Biotechnology Progress, ISSN: 87567938

Brian M. Castellano; Danming Tang; Scot A. Marsters; Cynthia Lam; Peter S. Liu; Christopher M. Rose; Wendy N. Sandoval; Avi Ashkenazi; Snedecor; Shahram Misaghi

January 1, 2023

Green Chemistry Articles of Interest to the Pharmaceutical Industry

Organic Process Research and Development, ISSN: 1520586X 10836160

Marian C. Bryan; Charlotte Dalton; Alba Díaz-Rodríguez; Jaika Doerfler; Oliver D. Engl; Alejandro Gimenez Molina; Vanessa Harawa; Christopher B. Kelly; Wei Li; Rachel Munday; Jan Pawlas; Paul Richardson; William J. Smith; Alan Steven; Balaram S. Takale; Jack A. Terrett; Daniel S. Treitler; Mingshuo Zeng

January 1, 2023

Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer

Nature, ISSN: 00280836

Luis A. Rojas; Zachary Sethna; Kevin C. Soares; Cristina Olcese; Nan Pang; Erin Patterson; Jayon Lihm; Nicholas Ceglia; Pablo Guasp; Alexander Chu; Rebecca Yu; Adrienne Kaya Chandra; Theresa Waters; Jennifer Ruan; Masataka Amisaki; Abderezak Zebboudj; Zagaa Odgerel; George Payne; Evelyna Derhovanessian; Felicitas Müller; Ina Rhee; Mahesh Yadav; Anton Dobrin; Michel Sadelain; Marta Łuksza; Noah Cohen; Laura Tang; Olca Basturk; Mithat Gonen; Seth S. Katz; Richard Kinh Do; Andrew S. Epstein; Parisa Momtaz; Wungki Park; Ryan Sugarman; Anna M. Varghese; Elizabeth Won; Avni Desai; Alice C. Wei; Michael I. D’Angelica; T. Peter Kingham; Ira Mellman; Taha Merghoub; Jedd D Wolchok; Ugur Sahin; Özlem Türeci; Benjamin D. Greenbaum; William R. Jarnagin; Jeffrey Drebin; O'Reilly; Vinod P. Balachandran

January 1, 2023

Tetramer-aided sorting and single-cell RNA sequencing facilitate transcriptional profiling of antigen-specific CD8+ T cells

Translational Oncology, ISSN: 19365233

Kamalakannan Rajasekaran; Xiangnan Guan; Alireza Tafazzol; Habib Hamidi; Martine Darwish; Mahesh Yadav

January 1, 2023

Integrated summary of immunogenicity of polatuzumab vedotin in patients with relapsed or refractory B-cell non-Hodgkin’s lymphoma

Frontiers in Immunology, ISSN: 16643224

Randall Dere; Richard L. Beardsley; Dan Lu; Tong Lu; Grace Ku; Gabriel Man; Van Nguyen; Surinder Kaur

January 1, 2023

Advanced Technologies and Automation in mES Cell Workflow

Methods in Molecular Biology, ISSN: 19406029 10643745

Charles Yu; Roger Caothien; Marques Jackson; Brian Nakao; Anna Pham; Lucinda Tam; Merone Roose-Girma

January 1, 2023

Safety of adjuvant atezolizumab after pneumonectomy/bilobectomy in stage II-IIIA non–small cell lung cancer in the randomized phase III IMpower010 trial

Journal of Thoracic and Cardiovascular Surgery, ISSN: 1097685X 00225223

Jay M. Lee; Eric Vallières; Beiying Ding; Ann Johnson; Jan Bhagwakar; Sanam Rashidi; Qian (Cindy) Zhu; Barbara Gitlitz; Benny Weksler; Kimberly Costas; Nasser Altorki

January 1, 2023

Toward Quantitative Models in Safety Assessment: A Case Study to Show Impact of Dose–Response Inference on hERG Inhibition Models

International Journal of Molecular Sciences, ISSN: 14220067 16616596

Fjodor Melnikov; Lennart T. Anger; Catrin Hasselgren

January 1, 2023

Fostering a High-Functioning Team in Cancer Care Using the 4R Oncology Model: Assessment in a Large Health System and a Blueprint for Other Institutions

JCO Oncology Practice, ISSN: 26881535 26881527

Raymond Liu; Christine B. Weldon; Elizabeth Linehan; Nancy Gordon; Thea Abbe; Marti Hennings; Henie James; Jed Katzel; Chun Ng; Megumi Tomita; Jeffrey B. Velotta; Stephanie Ossowski; Lori C. Sakoda; Sharon Likely Sprague; Anna Dowling; Kimberly Beringer; Arliene Ravelo; Elaine Yu; Julia R. Trosman

January 1, 2023

Relative bioavailability and food effect study of an oral suspension of alectinib in healthy volunteers using venipuncture and capillary microsampling

Clinical and Translational Science, ISSN: 17528062 17528054

Stephanie N. Liu; Priya Agarwal; Katja Heinig; Asim Datye; Carolina Sturm-Pellanda; Andrea Crugnola; Marc Arca; Dale Miles

January 1, 2023

ASIS-Seq: Transgene Insertion Site Mapping by Nanopore Adaptive Sampling

Methods in Molecular Biology, ISSN: 19406029 10643745

Charles Yu; Roger Caothien; Anna Pham; Lucinda Tam; Tuija M. Alcantar; Natasha Bacarro; Juan Reyes; Marques Jackson; Brian Nakao; Merone Roose-Girma

January 1, 2023

MSstatsPTM: Statistical Relative Quantification of Posttranslational Modifications in Bottom-Up Mass Spectrometry-Based Proteomics

Molecular and Cellular Proteomics, ISSN: 15359484 15359476

Devon Kohler; Tsung-Heng Tsai; Erik Verschueren; Ting Huang; Trent Hinkle; Lilian Phu; Meena Choi; Olga Vitek

January 1, 2023

Psychometrics of patient-reported bother from side effects of treatment single-items in industry-sponsored oncology trials

Quality of Life Research, ISSN: 15732649 09629343

Peter C. Trask; Tracy Holt; Timothy Pearman

January 1, 2023

A frequentist approach to dynamic borrowing

Biometrical Journal, ISSN: 03233847

Ruilin Li; Ray S. Lin; Jiangeng Huang; Lu Tian; Jiawen Zhu

January 1, 2023

Mass Spectrometry-Based Tissue Imaging of the Tumor Microenvironment

Methods in Molecular Biology,

Tyler Risom; Patrick Chang; Sandra Rost; James Ziai

January 1, 2023

The role of bacterial membrane vesicles in antibiotic resistance

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Craig R. MacNair; Man-Wah Tan

January 1, 2023

Liposomal Permeation Assay for Droplet-Scale Pharmacokinetic Screening

Journal of Medicinal Chemistry, ISSN: 15204804 00222623

Juan Hu; Alix I Chan; Emel Adaligil; Ivy Kekessie; Mifune Takahashi; Aimin Song; Christian N. Cunningham; Brian M. Paegel

January 1, 2023

Systematic pharmacological analysis of agonistic and antagonistic fibroblast growth factor receptor 1 MAbs reveals a similar unique mode of action

Journal of Biological Chemistry, ISSN: 1083351X 00219258

Jocelyn Chan; Joyce Chan; Lily Shao; Scott Stawicki; Victoria Pham; Robert W. Akita; Marc Hafner; Lisa Crocker; Kebing Yu; James T. Koerber; Gabriele Schaefer; Laetitia Comps-Agrar

January 1, 2023

An Interlaboratory Study to Identify Potential Visible Protein-Like Particle Standards

AAPS PharmSciTech, ISSN: 15309932

Srivalli N. Telikepalli; Michael J. Carrier; Dean C. Ripple; Greg Barnett; Ashwinkumar Bhirde; Donna Bolton; George M. Bou-Assaf; Erica Ferrari; Scott Leigh; Sophia Levitskaya-Seaman; Tim Menzen; Felix Nikels; Anna Riley; Miguel Saggu; Neha Sahni; Eric Vernooij; Klaus Wuchner

January 1, 2023

Effect of Buffer pH and Concentration on the Dissolution Rates of Sodium Indomethacin-Copovidone and Indomethacin-Copovidone Amorphous Solid Dispersions

Molecular Pharmaceutics, ISSN: 15438384

Cheng W. Chiang; Shijia Tang; Chen Mao; Yinshan Chen

January 1, 2023

Risks of Powder Flow Obstruction in Hopper and Bin Discharge in Solid Dosage Form Manufacture should be Predicted Under The Active Stress State

Journal of Pharmaceutical Sciences, ISSN: 00223549

Karthik Salish; Reto Maurer; Chen Mao

January 1, 2023

Comparisons between human and rodent hepatic glutathione S-Transferase activities reveal sex and species differences

Xenobiotica, ISSN: 00498254

Michael J. Doerksen; Denny Seo; Alexander D. Smith; Robert S. Jones; Michael W. H. Coughtrie; Abby C. Collier

January 1, 2023

Estimation of conditional power in the presence of auxiliary data

Statistics in Medicine, ISSN: 02776715

Xin Li; Godwin Yung; Jianchang Lin; Jian Zhu

January 1, 2023

Totality of evidence of the effectiveness of repurposed therapies for COVID-19: Can we use real-world studies alongside randomized controlled trials?

Clinical and Translational Science, ISSN: 17528054

Jaap W. Mandema; Hugh Montgomery; Louis Dron; Shuai Fu; Estelle Russek-Cohen; Christina Bromley; Samer Mouksassi; Amy Lalonde; Aaron Springford; Larry Tsai; Phil Ambery; Doug McNair; Nawab Qizilbash; Stuart Pocock; Névine Zariffa

January 1, 2023

Synthesis of 3-Functionalized 4-Quinolones from Readily Available Anthranilic Acids

Organic Letters, ISSN: 15237060

Lin Deng; Julie A. Deichert; Sierra C. Nguyen; Ian S. Young; Chong Han

January 1, 2023

Divarasib plus cetuximab in KRAS G12C-positive colorectal cancer: a phase 1b trial

Nature Medicine, ISSN: 10788956

Jayesh Desai; Guzman Alonso; Se Hyun Kim; Andrés Cervantes; Thomas Karasic; Laura Medina; Einat Shacham-Shmueli; Rasha Cosman; Alejandro Falcon; Eelke Gort; Guren; Erminia Massarelli; Miller; Luis Paz-Ares; Hans Prenen; Alessio Amatu; Chiara Cremolini; Tae Won Kim; Victor Moreno; Sai-Hong I. Ou; Alessandro Passardi; Adrian Sacher; Armando Santoro; Rafal Stec; Susanna Ulahannan; Kathryn Arbour; Patricia M. LoRusso; Jia Luo; Manish R. Patel; Yoonha Choi; Shi; Sandhya Mandlekar; Mark T. Lin; Stephanie Royer-Joo; Julie Chang; Tomi Jun; Neekesh V. Dharia; Jennifer L. Schutzman; Sae-Won Han

January 1, 2023

Balancing Yield, Purity, and Form: Finding the Sweet Spot for the Rework of the First Clinical Batch of Giredestrant (GDC-9545)

Organic Process Research and Development, ISSN: 10836160

Paroma Chakravarty; Jie Xu; Brandon Scott; Sarah J. Robinson; Karthik Nagapudi

January 1, 2023

Alternative therapeutic strategies to treat antibiotic-resistant pathogens

Nature Reviews Microbiology, ISSN: 17401526

Craig R. MacNair; Steven T. Rutherford; Man-Wah Tan

January 1, 2023

Development of a Streamlined Manufacturing Process for the Highly Substituted Quinazoline Core Present in KRAS G12C Inhibitor Divarasib

Organic Process Research and Development, ISSN: 10836160

Johannes Burkhard; Sebastian Herold; Christian Leitner; Haiming Zhang; Remy Angelaud; Qingping Tian; Chong Han; Francis Gosselin

January 1, 2023

Inhaled JAK Inhibitor GDC-0214 Nanoaggregate Powder Exhibits Improved Pharmacokinetic Profile in Rats Compared to the Micronized Form: Benefits of Thin Film Freezing

Molecular Pharmaceutics, ISSN: 15438384

Chaeho Moon; Sawittree Sahakijpijarn; Esther Y. Maier; David R. Taft; Miguel O. Jara; Tuangrat Praphawatvet; Rachana Manandhar; Nivedita Shetty; Joseph W. Lubach; Ajit S. Narang; Karthik Nagapudi; Robert O. Williams

January 1, 2023

Light-Driven Radiochemistry with Fluorine-18, Carbon-11 and Zirconium-89

Angewandte Chemie - International Edition, ISSN: 14337851

Daniel Lin; Laura M. Lechermann; Malcolm P. Huestis; Jan Marik; Jeroen B. I. Sap

January 1, 2023

Pharmacokinetics (PK) of Tiragolumab in First-in-Human Study in Patients with Mixed Solid Tumors (GO30103)

Journal of Clinical Pharmacology, ISSN: 00912700

Garralda; Do Youn Oh; Antoine Italiano; Philippe L. Bedard; Delord; Calvo; Patricia M. LoRusso; Zev A. Wainberg; Andrés Cervantes; Alejo Rodriguez-Vida; Colby S. Shemesh; Rucha Sane; Diana Mendus; Hao Ding; Robert Hendricks; Raymond D. Meng; Byoung Chul Cho; Tae Won Kim; Benjamin Wu

January 1, 2023

Correction to: Advanced Technologies and Automation in mES Cell Workflow (Transgenesis: Methods and Protocols, Methods in Molecular Biology, vol. 2631, https://doi.org/10.1007/978-1-0716-2990-1_7)

Methods in Molecular Biology, ISSN: 10643745

Anna Pham; Roger Caothien; Lucinda Tam; Diego Diaz; Marques Jackson; Brian Nakao; Charles Yu; Merone Roose-Girma

January 1, 2023

A phase I, randomized, ascending-dose study to assess safety, pharmacokinetics, and activity of GDC-8264, a RIP1 inhibitor, in healthy volunteers

Clinical and Translational Science, ISSN: 17528054

Nicholas Steven Jones; Smita Kshirsagar; Vishnu Mohanan; Vidya Ramakrishnan; Di Nucci; Ling Ma; Jialin Mao; Hao Ding; Sha Klabunde; Domagoj Vucic; Lin Pan; Annemarie N. Lekkerkerker; Yuan Chen; Michael E. Rothenberg

January 1, 2023

Utilizing PK and PD Biomarkers to Guide the First-in-Human Starting Dose Selection of MTBT1466A: A Novel Humanized Monoclonal Anti-TGFβ3 Antibody for the Treatment of Fibrotic Diseases

Journal of Pharmaceutical Sciences, ISSN: 00223549

Rajbharan Yadav; Siddharth Sukumaran; Jeff Lutman; Mayur S. Mitra; Wendy Halpern; Tianhe Sun; A F. Setiadi; Margaret Neighbors; X Rebecca Sheng; Victor Yip; Shen; Chang Liu; Lyrialle Han; Ayse Meric Ovacik; Yan Wu; Sara Glickstein; Rebecca Kunder; Joseph R. Arron; Lin Pan; Amrita Kamath; Stefanich

January 1, 2023

Author Correction: The power of genetic diversity in genome-wide association studies of lipids (Nature, (2021), 600, 7890, (675-679), 10.1038/s41586-021-04064-3)

Nature, ISSN: 00280836

Sarah E. Graham; Shoa L. Clarke; Kuan-Han H. Wu; Stavroula Kanoni; Greg J. M. Zajac; Shweta Ramdas; Ida Surakka; Ioanna Ntalla; Sailaja Vedantam; Thomas W. Winkler; Adam E. Locke; Eirini Marouli; Mi Yeong Hwang; Sohee Han; Akira Narita; Ananyo Choudhury; Amy R Bentley; Kenneth Ekoru; Anurag Verma; Bhavi Trivedi; Hilary C. Martin; Karen A. Hunt; Qin Hui; Derek Klarin; Xiang Zhu; Gudmar Thorleifsson; Anna Helgadottir; Daniel Gudbjartsson; Hilma Holm; Isleifur Olafsson; Masato Akiyama; Saori Sakaue; Chikashi Terao; Masahiro Kanai; Wei Zhou; Ben M. Brumpton; Humaira Rasheed; Sanni E. Ruotsalainen; Aki S. Havulinna; Yogasudha Veturi; QiPing Feng; Elisabeth A. Rosenthal; Todd Lingren; Jennifer Allen Pacheco; Sarah A. Pendergrass; Jeff Haessler; Franco Giulianini; Yuki Bradford; Jason E. Miller; Archie Campbell; Kuang Lin; Iona Y Millwood; George Hindy; Asif Rasheed; Jessica D Faul; Wei Zhao; David R Weir; Constance Turman; Hongyan Huang; Mariaelisa Graff; Anubha Mahajan; Michael R. Brown; Weihua Zhang; Ketian Yu; Ellen Schmidt; Anita Pandit; Stefan Gustafsson; Xianyong Yin; Jian’an Luan; Jing Hua Zhao; Fumihiko Matsuda; Hye-Mi Jang; Kyungheon Yoon; Carolina Medina-Gomez; Achilleas Pitsillides; Jouke-Jan Hottenga; Gonneke Willemsen; Andrew R Wood; Yingji Ji; Zishan Gao; Simon Haworth; Ruth E. Mitchell; Jin-Fang Chai; Mette Aadahl; Jie Yao; Ani Manichaikul; Helen R Warren; Julia Ramirez; Jette Bork-Jensen; Line L. Kårhus; Anuj Goel; Maria Sabater-Lleal; Raymond Noordam; Carlo Sidore; Edoardo Fiorillo; Aaron F. McDaid; Pedro Marques-Vidal; Matthias Wielscher; Stella Trompet; Naveed Sattar; Line T. Møllehave; Betina Thuesen; Matthias Munz; Lingyao Zeng; Jianfeng Huang; Bin Yang; Alaitz Poveda; Azra Kurbasic; Claudia Lamina; Lukas Forer; Markus Scholz; Tessel E. Galesloot; Jonathan P. Bradfield; E. Warwick Daw; Joseph M. Zmuda; Jonathan S. Mitchell; Christian Fuchsberger; Henry Christensen; Jennifer A Brody; Mary F. Feitosa; Mary K. Wojczynski; Michael Preuss; Massimo Mangino; Paraskevi Christofidou; Niek Verweij; Jan W. Benjamins; Jorgen Engmann; Rachel L. Kember; Roderick Slieker; Ken Sin Lo; Nuno R. Zilhao; Phuong Le; Marcus E. Kleber; Graciela E Delgado; Shaofeng Huo; Daisuke D. Ikeda; Hiroyuki Iha; Jian Yang; Jun Liu; Hampton L Leonard; Jonathan Marten; Börge Schmidt; Marina Arendt; Laura J. Smyth; Marisa Cañadas-Garre; Chaolong Wang; Masahiro Nakatochi; Andrew K. Wong; Nina Hutri-Kähönen; Xueling Sim; Rui Xia; Alicia Huerta-Chagoya; Juan Carlos Fernandez-Lopez; Valeriya Lyssenko; Meraj Ahmed; Anne U. Jackson; Noha A Yousri; Marguerite R. Irvin; Christopher Oldmeadow; Han-Na Kim; Seungho Ryu; Paul R H J Timmers; Liubov Arbeeva; Rajkumar Dorajoo; Leslie A. Lange; Xiaoran Chai; Gauri Prasad; Laura Lorés-Motta; Marc Pauper; Jirong Long; Xiaohui Li; Elizabeth Theusch; Fumihiko Takeuchi; Cassandra N Spracklen; Anu Loukola; Sailalitha Bollepalli; Sophie C. Warner; Ya Xing Wang; Wen B. Wei; Teresa Nutile; Daniela Ruggiero; Yun Ju Sung; Yi-Jen Hung; Shufeng Chen; Fangchao Liu; Jingyun Yang; Katherine A. Kentistou; Mathias M. Gorski; Marco Brumat; Karina Meidtner; Lawrence F. Bielak; Jennifer A Smith; Prashantha Hebbar; Aliki-Eleni Farmaki; Edith Hofer; Maoxuan Lin; Chao Xue; Jifeng Zhang; Maria Pina Concas; Simona Vaccargiu; Peter J. Van Der Most; Nina Pitkänen; Brian E. Cade; Jiwon Lee; Sander W. van der Laan; Kumaraswamy Naidu Chitrala; Stefan Weiss; Martina E. Zimmermann; Jong-Young Lee; Hyeok Sun Choi; Maria Nethander; Sandra Freitag-Wolf; Lorraine Southam; N. William Rayner; Carol A Wang; Shih-Yi Lin; Jun-Sing Wang; Christian Couture; Leo-Pekka Lyytikäinen; Kjell Nikus; Gabriel Cuellar-Partida; Henrik Vestergaard; Bertha Hildalgo; Olga Giannakopoulou; Qiuyin Cai; Morgan O. Obura; Jessica Van Setten; Xiaoyin Li; Karen Schwander; Natalie Terzikhan; Jae Hun Shin; Rebecca D. Jackson; Alex Reiner; Lisa W. Martin; Zhengming Chen; Liming Li; Heather M. Highland; Kristin L. Young; Takahisa Kawaguchi; Joachim Thiery; Joshua C. Bis; Girish Nadkarni; Lenore J. Launer; Huaixing Li; Michael A. Nalls; Olli T. Raitakari; Sahoko Ichihara; Sarah H. Wild; Christopher P. Nelson; Harry Campbell; Susanne Jäger; Toru Nabika; Fahd Al-Mulla; Harri Niinikoski; Peter S. Braund; Ivana Kolcic; Peter Kovacs; Tota Giardoglou; Tomohiro Katsuya; Konain Fatima Bhatti; Dominique P V de Kleijn; Gert J de Borst; Eung Kweon Kim; Hieab H. H. Adams; M Arfan Ikram; Xiaofeng Zhu; Folkert W Asselbergs; Adriaan O. Kraaijeveld; Joline Beulens; Xiao-Ou Shu; Loukianos S. Rallidis; Oluf Pedersen; Torben Hansen; Paul Mitchell; Alex W. Hewitt; Mika Kähönen; Louis Perusse; Claude Bouchard; Anke Tönjes; Yii-Der Ida Chen; Craig E. Pennell; Trevor A Mori; Wolfgang Lieb; Andre Franke; Claes Ohlsson; Dan Mellström; Yoon Shin Cho; Hyejin Lee; Jian-Min Yuan; Woon-Puay Koh; Sang Youl Rhee; Jeong-Taek Woo; Iris M. Heid; Klaus J. Stark; Henry Völzke; Georg Homuth; Michele K Evans; Alan B Zonderman; Ozren Polasek; Gerard Pasterkamp; Imo E. Hoefer; Susan Redline; Katja Pahkala; Albertine J Oldehinkel; Harold Snieder; Ginevra Biino; Reinhold Schmidt; Helena Schmidt; Y. Eugene Chen; Stefania Bandinelli; George Dedoussis; Thangavel Alphonse Thanaraj; Sharon L. R. Kardia; Norihiro Kato; Matthias B Schulze; Giorgia Girotto; Bettina Jung; Carsten A. Böger; Peter K Joshi; David A. Bennett; Philip L. De Jager; Xiangfeng Lu; Vasiliki Mamakou; Morris Brown; Mark J. Caulfield; Patricia B Munroe; Xiuqing Guo; Marina Ciullo; Jost B Jonas; Nilesh J. Samani; Jaakko Kaprio; Päivi Pajukanta; Linda S. Adair; Sonny Augustin Bechayda; H. Janaka de Silva; Ananda R. Wickremasinghe; Ronald M. Krauss; Jer-Yuarn Wu; Wei Zheng; Anneke I. den Hollander; Dwaipayan Bharadwaj; Adolfo Correa; James G. Wilson; Lars Lind; Chew-Kiat Heng; Amanda E. Nelson; Yvonne M. Golightly; James F Wilson; Brenda Penninx; Hyung-Lae Kim; John Attia; Rodney J. Scott; Rao; Donna K. Arnett; Steven C Hunt; Mark Walker; Heikki A. Koistinen; Giriraj Ratan Chandak; Chittaranjan S Yajnik; Josep M. Mercader; Teresa Tusié-Luna; Carlos A. Aguilar-Salinas; Clicerio Gonzalez Villalpando; Lorena Orozco; Myriam Fornage; E-Shyong Tai; Rob M. van Dam; Terho Lehtimäki; Nish Chaturvedi; Mitsuhiro Yokota; Jianjun Liu; Dermot F. Reilly; Amy J. McKnight; Frank Kee; Karl-Heinz Jöckel; Mark I. McCarthy; Colin Palmer; Veronique Vitart; Caroline Hayward; Eleanor Simonsick; Cornelia M. van Duijn; Fan Lu; Jia Qu; Haretsugu Hishigaki; Xu Lin; Winfried März; Esteban J. Parra; Miguel Cruz; Vilmundur Gudnason; Jean-Claude Tardif; Guillaume Lettre; Leen M. T Hart; Petra J M Elders; Scott M. Damrauer; Meena Kumari; Mika Kivimaki; Pim van der Harst; Tim D. Spector; Ruth J. F. Loos; Michael A. Province; Bruce M. Psaty; Ivan Brandslund; Peter P Pramstaller; Kaare Christensen; Samuli Ripatti; Elisabeth Widén; Hakon Hakonarson; Struan F.A. Grant; Lambertus A. 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Synthesis of a Highly Functionalized Quinazoline Organozinc toward KRAS G12C Inhibitor Divarasib (GDC-6036), Enabled through Continuous Flow Chemistry

Organic Process Research and Development, ISSN: 10836160

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Single-Agent Divarasib (GDC-6036) in Solid Tumors with a KRAS G12C Mutation.

New England Journal of Medicine, ISSN: 00284793

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Molecular residual disease detection in resected, muscle-invasive urothelial cancer with a tissue-based comprehensive genomic profiling–informed personalized monitoring assay

Frontiers in Oncology,

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