Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 6501 - 6550 OF 15796 RESULTS

Genetic variability of VEGF pathway genes in six randomized phase III trials assessing the addition of bevacizumab to standard therapy
Angiogenesis, ISSN: 15737209 09696970
Sanne De Haas; Paul Delmar; Aruna T. Bansal; Matthieu Moisse; David W. Miles; Natasha Leighl; Bernard Escudier; Eric Van Cutsem; Peter Carmeliet; Stefan J. Scherer; Celine Pallaud; Diether Lambrechts
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Type i IFN induces IL-10 production in an IL-27-Independent manner and blocks responsiveness to IFN-γ for production of IL-12 and bacterial killing in mycobacterium tuberculosis-infected macrophages
Journal of Immunology, ISSN: 15506606 00221767
Finlay W. McNab; John Ewbank; Ashleigh Howes; Lucia Moreira-Teixeira; Anna Martirosyan; Nico Ghilardi; Margarida Saraiva; Anne O'Garra
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Hypothesis-independent pathway analysis implicates GABA and Acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma
Human Genetics, ISSN: 14321203 03406717
Jessica Cooke Bailey; Brian L. Yaspan; Louis R. Pasquale; Michael A. Hauser; Jae H. Kang; Stephanie J. Loomis; Murray Brilliant; Donald L. Budenz; Christen; John Fingert; Douglas Gaasterland; Terry Gaasterland; Peter Kraft; Richard K. Lee; Paul R. Lichter; Yutao Liu; Catherine A. McCarty; Sayoko E. Moroi; Julia E. Richards; Tony Realini; Schuman; William K. Scott; Kuldev Singh; Arthur J. Sit; Douglas Vollrath; Gadi Wollstein; Donald J. Zack; Kang Zhang; Brian W. Kunkle; R. Rand Allingham; Robert N. Weinreb; Jonathan L. Haines; Janey L. Wiggs
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GATA-3 dose-dependent checkpoints in early T cell commitment
Journal of Immunology, ISSN: 15506606 00221767
Deirdre D. Scripture-Adams; Sagar S. Damle; Long Li; Koorosh J. Elihu; Shuyang Qin; Alexandra M. Arias; Robert R. Butler; Ameya Champhekar; Jingli A. Zhang; Ellen V. Rothenberg
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Impact of betaine HCl on the absorption of orally administered drugs
Advances in Medicine and Biology,
Marc R. Yago; Joseph A. Ware; Leslie Z. Benet
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Rituximab extended schedule or re-treatment trial for low-tumor burden follicular lymphoma: Eastern cooperative oncology group protocol E4402
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Brad Kahl; Fangxin Hong; Marna Williams; Randy D. Gascoyne; Lynne I. Wagner; John C. Krauss; Thomas M. Habermann; Lode J. Swinnen; Stephen J. Schuster; Christopher G. Peterson; Mark D. Sborov; S. Eric Martin; Matthias Weiss; W. Christopher Ehmann; Sandra J. Horning
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Recommendations from a global cross-company data sharing initiative on the incorporation of recovery phase animals in safety assessment studies to support first-in-human clinical trials
Regulatory Toxicology and Pharmacology, ISSN: 10960295 02732300
Fiona Sewell; Kathryn Chapman; Paul Baldrick; David Brewster; Alan Broadmeadow; Paul Brown; Leigh Ann Burns-Naas; Janet Clarke; Alex Constan; Jessica A. Couch; Oliver Czupalla; Andy Danks; Joseph DeGeorge; Lolke de Haan; Klaudia Hettinger; Marilyn Hill; Matthias Festag; Abby Jacobs; David Jacobson-Kram; Stephan J. Kopytek; Helga Lorenz; Sophia Gry Moesgaard; Emma Moore; Markku Pasanen; Rick Perry; Ian Ragan; Sally Robinson; Petra M. Schmitt; Brian Short; Beatriz Silva Lima; Diane Smith; Sue Sparrow; Yvette van Bekkum; David Jones
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The pharmaceutical development of rhDNase (Dornase Alpha) for the treatment of cystic fibrosis
Mucosal Delivery of Biopharmaceuticals: Biology, Challenges and Strategies,
Steven J. Shire; Thomas M. Scherer
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Structure based design of novel 6,5 heterobicyclic mitogen-activated protein kinase kinase (MEK) inhibitors leading to the discovery of imidazo[1,5-a] pyrazine G-479
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Kirk D. Robarge; Wendy Lee; Eigenbrot; Ultsch; Wiesmann; Robert Heald; Steve Price; Joanne F. M. Hewitt; Philip Jackson; Pascal P. A. Savy; Brenda Burton; Edna F. Choo; Jodie Pang; Jason Boggs; April Yang; Yang Xiao; Matthew Baumgardner
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Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells
Cancer Research, ISSN: 15387445 00085472
Teemu T. Junttila; Ji Li; Jennifer A. Johnston; Maria Hristopoulos; Robyn Clark; Diego Ellerman; Bu-Er Wang; Yijin Li; Mary Mathieu; Guangmin Li; Judy Young; Luis; Gail L. Phillips; Stefanich; Christoph Spiess; Andrew G. Polson; Bryan Irving; Justin M. Scheer; Melissa Junttila; Dennis; Robert F. Kelley; Klara Totpal; Allen Ebens
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Hominoid-specific enzyme GLUD2 promotes growth of IDH1R132Hglioma
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Ruihuan Chen; Merry C. Nishimura; Samir Kharbanda; Franklin V. Peale Jr.; Yuzhong Deng; Anneleen Daemen; William F. Forrest; Mandy Kwong; Maj Hedehus; Georgia Hatzivassiliou; Lori S. Friedman; Phillips
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Determination of trace level genotoxic impurities in small molecule drug substances using conventional headspace gas chromatography with contemporary ionic liquid diluents and electron capture detection
Journal of Chromatography A, ISSN: 18733778 00219673
Tien Ho; Peter M. Yehl; Nik P. Chetwyn; Jin Wang; Jared L. Anderson; Qiqing Zhong
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Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia
Nature, ISSN: 14764687 00280836
Monique Dail; Jason Wong; Jessica Lawrence; Daniel O'Connor; Joy Nakitandwe; Shann-Ching Chen; Jin Xu; Leslie Lee; Keiko Akagi; Qing Li; Jon C. Aster; Warren S. Pear; James R. Downing; Deepak Sampath; Kevin Shannon
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Homeostatic IL-23 receptor signaling limits Th17 response through IL-22-mediated containment of commensal microbiota
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Vincent Feng-Sheng Shih; Jennifer Cox; Noelyn Kljavin; Hart S. Dengler; Mike Reichelt; Pawan Kumar; Linda Rangell; Jay K. Kolls; Laurie Diehl; Wenjun Ouyang; Nico Ghilardi
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Global, regional, and national levels and causes of maternal mortality during 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013
The Lancet, ISSN: 1474547X 01406736
Nicholas Kassebaum; Amelia Bertozzi-Villa; Megan Coggeshall; Katya Shackelford; Caitlyn Steiner; Kyle R. Heuton; Diego Gonzalez-Medina; Ryan M. Barber; Chantal Huynh; Daniel Dicker; Tara Templin; Timothy M. Wolock; Ayse Abbasoglu Ozgoren; Foad Abd-Allah; Semaw F. Abera; Ibrahim Abubakar; Tom Achoki; Ademola Adelekan; Zanfina Ademi; Arsène K. Adou; Josef C. Adsuar; Emilie E. Agardh; Dickens Akena; Deena Alasfoor; Zewdie A. Alemu; Rafael Alfonso-Cristancho; Samia Alhabib; Raghib Ali; Mazin J. Al Kahbouri; Francois Alla; Peter J. Allen; Mohammad Abdulaziz AlMazroa; Ubai Alsharif; Elena Alvarez; Nelson Alvis-Guzman; Adansi A. Amankwaa; Azmeraw T. Amare; Heresh Amini; Walid Ammar; Carl Abelardo T. Antonio; Palwasha Anwari; Johan Arnlov; Valentina S. Arsic Arsenijevic; Al Artaman; Majed Masoud Asad; Rana J. Asghar; Reza Assadi; Lydia S. Atkins; Alaa Badawi; Kalpana Balakrishnan; Arindam Basu; Sanjay Basu; Justin Beardsley; Neeraj Bedi; Tolesa Bekele; Michelle L. Bell; Eduardo Bernabe; Tariku Jibat Beyene; Zulfiqar Bhutta; Aref Bin Abdulhak; Jed D. Blore; Berrak Bora Basara; Dipan Bose; Nicholas J.K. Breitborde; Rosario Cardenas; Carlos A. Castaneda-Orjuela; Ruben Estanislao Castro; Ferran Catala-Lopez; Alanur Cavlin; Jung-Chen Chang; Xuan Che; Costas A. Christophi; Sumeet S. Chugh; Massimo Cirillo; Samantha M. Colquhoun; Christian Kieling; Cyrus Cooper; Iuri Da Costa Leite; Lalit Dandona; Rakhi Dandona; Adrian Davis; Anand Dayama; Louisa Degenhardt; Diego De Leo; Borja Del Pozo-Cruz; Kebede Deribe; Muluken Dessalegn; Gabrielle A. DeVeber; Samath D. Dharmaratne; Uʇur Dilmen; Eric L. Ding; Rob E. Dorrington; Tim R. Driscoll; Sergey P. Ermakov; Alireza Esteghamati; Emerito Jose A. Faraon; Farshad Farzadfar; Manuela Mendonca Felicio; Seyed-Mohammad Fereshtehnejad; Graça Maria Ferreira De Lima; Mohammad H. Forouzanfar; Elisabeth B. França; Lynne Gaffikin; Ketevan Gambashidze; Fortune G. Gankpe; Ana Cristina Garcia; Johanna M. Geleijnse; Katherine B. Gibney; Maurice Giroud; Elizabeth L. Glaser; Ketevan Goginashvili; Philimon Gona; Dinorah González-Castell; Atsushi Goto; Hebe N. Gouda; Harish C. Gugnani; Rahul Gupta; Rajeev Gupta; Nima Hafezi-Nejad; Randah R. Hamadeh; Mouhanad Hammami; Graeme J. Hankey; Hilda L. Harb; Rasmus Havmoeller; Simon Hay; Ileana B. Heredia Pi; Hans W. Hoek; Francis A. Mhimbira; Damian G. Hoy; Abdullatif Husseini; Bulat T. Idrisov; Kaire Innos; Manami Inoue; Kathryn H. Jacobsen; Eiman Jahangir; Sun Ha Jee; Paul N. Jensen; Vivekanand Jha; Guohong Jiang; Jost B. Jonas; Knud Juel; Edmond Kato Kabagambe; Haidong Kan; Karam; Andre Karch; Corine Kakizi Karema; Anil Kaul; Norito Kawakami; Konstantin Kazanjan; Dhruv S. Kazi; Andrew H. Kemp; Andre P. Kengne; Maia Kereselidze; Yousef S. Khader; Shams Eldin A.H. Khalifa; Ejaz A. Khan; Young-Ho Khang; Luke Knibbs; Yoshihiro Kokubo; Soewarta Kosen; Barthelemy Kuate Defo; Chanda Kulkarni; Veena S. Kulkarni; G Anil Kumar; Kaushalendra Kumar; Ravi B. Kumar; Gene F. Kwan; Taavi Lai; Ratilal Lalloo; Hilton Lam; Van C. Lansingh; Anders Larsson; Jong-Tae Lee; James Leigh; Mall Leinsalu; Ricky Leung; Xiaohong Li; Yichong Li; Yongmei Li; Juan Liang; Xiaofeng Liang; Stephen Lim; Hsien-Ho Lin; Steven E. Lipshultz; Shiwei Liu; Yang Liu; Belinda K. Lloyd; Stephanie J. London; Paulo A. Lotufo; Jixiang Ma; Stefan Ma; Vasco Manuel Pedro Machado; Nana Kwaku Mainoo; Marek Majdan; Christopher C. Mapoma; Wagner Marcenes; Melvin B. Marzan; Amanda J. Mason-Jones; Man Mohan Mehndiratta; Fabiola Mejia-Rodriguez; Ziad A. Memish; Walter Mendoza; Ted R. Miller; Edward J. Mills; Ali H. Mokdad; Glen L. Mola; Lorenzo Monasta; Jonathan De La Cruz Monis; Julio Cesar Montañez Hernandez; Ami R. Moore; Maziar Moradi-Lakeh; Rintaro Mori; Ulrich O. Mueller; Mitsuru Mukaigawara; Aliya Naheed; Kovin S. Naidoo; Devina Nand; Vinay Nangia; Denis Nash; Chakib Nejjari; Robert G. Nelson; Sudan P. Neupane; Charles R. Newton; Marie Ng; Mark J. Nieuwenhuijsen; Muhammad I. Nisar; Sandra Nolte; Ole F. Norheim; Luke Nyakarahuka; In Hwan Oh; Takayoshi Ohkubo; Bolajoko O. Olusanya; Saad B. Omer; John Nelson Opio; Orish Ebere Orisakwe; Jeyaraj D. Pandian; Christina Papachristou; Jae-Hyun Park; Angel J. Paternina Caicedo; Scott B. Patten; Vinod K. Paul; Boris I. Pavlin; Neil Pearce; David M. Pereira; Konrad Pesudovs; Max Petzold; Dan Poenaru; Guilherme V. Polanczyk; Suzanne Polinder; Dan Pope; Farshad Pourmalek; Dima Qato; Quistberg; Anwar Rafay; Kazem Rahimi; Vafa Rahimi-Movaghar; Sajjad Ur Rahman; Murugesan Raju; Saleem M. Rana; Amany Refaat; Luca Ronfani; Nobhojit Roy; Tania Georgina Sánchez Pimienta; Mohammad Ali Sahraian; Joshua A. Salomon; Uchechukwu Sampson; Itamar S. Santos; Monika Sawhney; Felix Sayinzoga; Ione J.C. Schneider; Austin E. Schumacher; David C. Schwebel; Soraya Seedat; Sadaf G. Sepanlou; Edson E. Servan-Mori; Marina Shakh-Nazarova; Sara Sheikhbahaei; Kenji Shibuya; Hwashin Hyun Shin; Ivy Shiue; Inga D. Sigfusdottir; Donald H. Silberberg; Andrea P. Silva; Jasvinder A. Singh; Vegard Skirbekk; Karen Sliwa; Sergey S. Soshnikov; Luciano A. Sposato; Chandrashekhar T. Sreeramareddy; Konstantinos Stroumpoulis; Lela Sturua; Bryan L. Sykes; Karen M. Tabb; Roberto Tchio Talongwa; Feng Tan; Carolina Maria Teixeira; Eric Yeboah Tenkorang; Abdullah Sulieman Terkawi; Andrew L. Thorne-Lyman; David L. Tirschwell; Charles D.A. Wolfe; Bach X. Tran; Miltiadis K. Tsilimbaris; Uche S. Uchendu; Kingsley N. Ukwaja; Eduardo A. Undurraga; Selen B. Uzun; Andrew J. Vallely; Coen H. Van Gool; Tommi J. Vasankari; Monica S. Vavilala; Narayanaswamy Venketasubramanian; Salvador Villalpando; Francesco S. Violante; Vasiliy Victorovich Vlassov; Theo Vos; Stephen Waller; Haidong Wang; Linhong Wang; XiaoRong Wang; Yanping Wang; Scott Weichenthal; Elisabete Weiderpass; Robert G. Weintraub; Ronny Westerman; James D. Wilkinson; Solomon M. Woldeyohannes; John Q. Wong; Muluemebet Abera Wordofa; Gelin Xu; Yang C. Yang; Yuichiro Yano; Gokalp K. Yentur; Paul Yip; Naohiro Yonemoto; Seok-Jun Yoon; Mustafa Younis; Chuanhua Yu; Kim Yun Jin; Maysaa El Sayed Zaki; Yong Zhao; Yingfeng Zheng; Maigeng Zhou; Jun Zhu; Xiao Nong Zou; Alan D. Lopez; Mohsen Naghavi; Christopher J.L. Murray; Rafael Lozano
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Global, regional, and national levels and causes of maternal mortality during 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013
The Lancet, ISSN: 1474547X 01406736
Nicholas Kassebaum; Amelia Bertozzi-Villa; Megan Coggeshall; Katya Shackelford; Caitlyn Steiner; Kyle R. Heuton; Diego Gonzalez-Medina; Ryan M. Barber; Chantal Huynh; Daniel Dicker; Tara Templin; Timothy M. Wolock; Ayse Abbasoglu Ozgoren; Foad Abd-Allah; Semaw F. Abera; Ibrahim Abubakar; Tom Achoki; Ademola Adelekan; Zanfina Ademi; Arsène K. Adou; Josef C. Adsuar; Emilie E. Agardh; Dickens Akena; Deena Alasfoor; Zewdie A. Alemu; Rafael Alfonso-Cristancho; Samia Alhabib; Raghib Ali; Mazin J. Al Kahbouri; Francois Alla; Peter J. Allen; Mohammad Abdulaziz AlMazroa; Ubai Alsharif; Elena Alvarez; Nelson Alvis-Guzman; Adansi A. Amankwaa; Azmeraw T. Amare; Heresh Amini; Walid Ammar; Carl Abelardo T. Antonio; Palwasha Anwari; Johan Arnlov; Valentina S. Arsic Arsenijevic; Al Artaman; Majed Masoud Asad; Rana J. Asghar; Reza Assadi; Lydia S. Atkins; Alaa Badawi; Kalpana Balakrishnan; Arindam Basu; Sanjay Basu; Justin Beardsley; Neeraj Bedi; Tolesa Bekele; Michelle L. Bell; Eduardo Bernabe; Tariku J. Beyene; Zulfiqar Bhutta; Aref Bin Abdulhak; Jed D. Blore; Berrak Bora Basara; Dipan Bose; Nicholas J.K. Breitborde; Rosario Cardenas; Carlos A. Castaneda-Orjuela; Ruben Estanislao Castro; Ferran Catala-Lopez; Alanur Cavlin; Jung-Chen Chang; Xuan Che; Costas A. Christophi; Sumeet S. Chugh; Massimo Cirillo; Samantha M. Colquhoun; Christian Kieling; Cyrus Cooper; Iuri Da Costa Leite; Lalit Dandona; Rakhi Dandona; Adrian Davis; Anand Dayama; Louisa Degenhardt; Diego De Leo; Borja Del Pozo-Cruz; Kebede Deribe; Muluken Dessalegn; Gabrielle A. DeVeber; Samath D. Dharmaratne; Uʇur Dilmen; Eric L. Ding; Rob E. Dorrington; Tim R. Driscoll; Sergey P. Ermakov; Alireza Esteghamati; Emerito Jose A. Faraon; Farshad Farzadfar; Manuela Mendonca Felicio; Seyed-Mohammad Fereshtehnejad; Graça Maria Ferreira De Lima; Mohammad H. Forouzanfar; Elisabeth B. França; Lynne Gaffikin; Ketevan Gambashidze; Fortune G. Gankpe; Ana Cristina Garcia; Johanna M. Geleijnse; Katherine B. Gibney; Maurice Giroud; Elizabeth L. Glaser; Ketevan Goginashvili; Philimon Gona; Dinorah González-Castell; Atsushi Goto; Hebe N. Gouda; Harish C. Gugnani; Rahul Gupta; Rajeev Gupta; Nima Hafezi-Nejad; Randah R. Hamadeh; Mouhanad Hammami; Graeme J. Hankey; Hilda L. Harb; Rasmus Havmoeller; Simon Hay; Ileana B. Heredia Pi; Hans W. Hoek; Francis A. Mhimbira; Damian G. Hoy; Abdullatif Husseini; Bulat T. Idrisov; Kaire Innos; Manami Inoue; Kathryn H. Jacobsen; Eiman Jahangir; Sun Ha Jee; Paul N. Jensen; Vivekanand Jha; Guohong Jiang; Jost B. Jonas; Knud Juel; Edmond Kato Kabagambe; Haidong Kan; Karam; Andre Karch; Corine Kakizi Karema; Anil Kaul; Norito Kawakami; Konstantin Kazanjan; Dhruv S. Kazi; Andrew H. Kemp; Andre P. Kengne; Maia Kereselidze; Yousef S. Khader; Shams Eldin A.H. Khalifa; Ejaz A. Khan; Young-Ho Khang; Luke Knibbs; Yoshihiro Kokubo; Soewarta Kosen; Barthelemy Kuate Defo; Chanda Kulkarni; Veena S. Kulkarni; G Anil Kumar; Kaushalendra Kumar; Ravi B. Kumar; Gene F. Kwan; Taavi Lai; Ratilal Lalloo; Hilton Lam; Van C. Lansingh; Anders Larsson; Jong-Tae Lee; James Leigh; Mall Leinsalu; Ricky Leung; Xiaohong Li; Yichong Li; Yongmei Li; Juan Liang; Xiofeng Liang; Stephen Lim; Hsien-Ho Lin; Steven E. Lipshultz; Shiwei Liu; Yang Liu; Belinda K. Lloyd; Stephanie J. London; Paulo A. Lotufo; Jixiang Ma; Stefan Ma; Vasco Manuel Pedro Machado; Nana Kwaku Mainoo; Marek Majdan; Christopher C. Mapoma; Wagner Marcenes; Melvin B. Marzan; Amanda J. Mason-Jones; Man Mohan Mehndiratta; Fabiola Mejia-Rodriguez; Ziad A. Memish; Walter Mendoza; Ted R. Miller; Edward J. Mills; Ali H. Mokdad; Glen L. Mola; Lorenzo Monasta; Jonathan De La Cruz Monis; Julio Cesar Montañez Hernandez; Ami R. Moore; Maziar Moradi-Lakeh; Rintaro Mori; Ulrich O. Mueller; Mitsuru Mukaigawara; Aliya Naheed; Kovin S. Naidoo; Devina Nand; Vinay Nangia; Denis Nash; Chakib Nejjari; Robert G. Nelson; Sudan P. Neupane; Charles R. Newton; Marie Ng; Mark J. Nieuwenhuijsen; Muhammad I. Nisar; Sandra Nolte; Ole F. Norheim; Luke Nyakarahuka; In Hwan Oh; Takayoshi Ohkubo; Bolajoko O. Olusanya; Saad B. Omer; John Nelson Opio; Orish Ebere Orisakwe; Jeyaraj D. Pandian; Christina Papachristou; Jae-Hyun Park; Angel J. Paternina Caicedo; Scott B. Patten; Vinod K. Paul; Boris I. Pavlin; Neil Pearce; David M. Pereira; Konrad Pesudovs; Max Petzold; Dan Poenaru; Guilherme V. Polanczyk; Suzanne Polinder; Dan Pope; Farshad Pourmalek; Dima Qato; Quistberg; Anwar Rafay; Kazem Rahimi; Vafa Rahimi-Movaghar; Sajjad Ur Rahman; Murugesan Raju; Saleem M. Rana; Amany Refaat; Luca Ronfani; Nobhojit Roy; Tania Georgina Sánchez Pimienta; Mohammad Ali Sahraian; Joshua A. Salomon; Uchechukwu Sampson; Itamar S. Santos; Monika Sawhney; Felix Sayinzoga; Ione J.C. Schneider; Austin E. Schumacher; David C. Schwebel; Soraya Seedat; Sadaf G. Sepanlou; Edson E. Servan-Mori; Marina Shakh-Nazarova; Sara Sheikhbahaei; Kenji Shibuya; Hwashin Hyun Shin; Ivy Shiue; Inga D. Sigfusdottir; Donald H. Silberberg; Andrea P. Silva; Jasvinder A. Singh; Vegard Skirbekk; Karen Sliwa; Sergey S. Soshnikov; Luciano A. Sposato; Chandrashekhar T. Sreeramareddy; Konstantinos Stroumpoulis; Lela Sturua; Bryan L. Sykes; Karen M. Tabb; Roberto Tchio Talongwa; Feng Tan; Carolina Maria Teixeira; Eric Yeboah Tenkorang; Abdullah Sulieman Terkawi; Andrew L. Thorne-Lyman; David L. Tirschwell; Charles D.A. Wolfe; Bach X. Tran; Miltiadis K. Tsilimbaris; Uche S. Uchendu; Kingsley N. Ukwaja; Eduardo A. Undurraga; Selen B. Uzun; Andrew J. Vallely; Coen H. Van Gool; Tommi J. Vasankari; Monica S. Vavilala; Narayanaswamy Venketasubramanian; Salvador Villalpando; Francesco S. Violante; Vasiliy Victorovich Vlassov; Theo Vos; Stephen Waller; Haidong Wang; Linhong Wang; XiaoRong Wang; Yanping Wang; Scott Weichenthal; Elisabete Weiderpass; Robert G. Weintraub; Ronny Westerman; James D. Wilkinson; Solomon M. Woldeyohannes; John Q. Wong; Muluemebet Abera Wordofa; Gelin Xu; Yang C. Yang; Yuichiro Yano; Gokalp K. Yentur; Paul Yip; Naohiro Yonemoto; Seok-Jun Yoon; Mustafa Younis; Chuanhua Yu; Kim Yun Jin; Maysaa El Sayed Zaki; Yong Zhao; Yingfeng Zheng; Maigeng Zhou; Jun Zhu; Xiao Nong Zou; Alan D. Lopez; Mohsen Naghavi; Christopher J.L. Murray; Rafael Lozano
View on Scopus
Global, regional, and national levels and causes of maternal mortality during 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013
The Lancet, ISSN: 1474547X 01406736
Nicholas Kassebaum; Amelia Bertozzi-Villa; Megan Coggeshall; Katya Shackelford; Caitlyn Steiner; Kyle R. Heuton; Diego Gonzalez-Medina; Ryan M. Barber; Chantal Huynh; Daniel Dicker; Tara Templin; Timothy M. Wolock; Ayse Abbasoglu Ozgoren; Foad Abd-Allah; Semaw F. Abera; Ibrahim Abubakar; Tom Achoki; Ademola Adelekan; Zanfina Ademi; Arsène K. Adou; Josef C. Adsuar; Emilie E. Agardh; Dickens Akena; Deena Alasfoor; Zewdie A. Alemu; Rafael Alfonso-Cristancho; Samia Alhabib; Raghib Ali; Mazin J. Al Kahbouri; Francois Alla; Peter J. Allen; Mohammad Abdulaziz AlMazroa; Ubai Alsharif; Elena Alvarez; Nelson Alvis-Guzman; Adansi A. Amankwaa; Azmeraw T. Amare; Heresh Amini; Walid Ammar; Carl Abelardo T. Antonio; Palwasha Anwari; Johan Arnlov; Valentina S. Arsic Arsenijevic; Al Artaman; Majed Masoud Asad; Rana J. Asghar; Reza Assadi; Lydia S. Atkins; Alaa Badawi; Kalpana Balakrishnan; Arindam Basu; Sanjay Basu; Justin Beardsley; Neeraj Bedi; Tolesa Bekele; Michelle L. Bell; Eduardo Bernabe; Tariku J. Beyene; Zulfiqar Bhutta; Aref Bin Abdulhak; Jed D. Blore; Berrak Bora Basara; Dipan Bose; Nicholas J.K. Breitborde; Rosario Cardenas; Carlos A. Castaneda-Orjuela; Ruben Estanislao Castro; Ferran Catala-Lopez; Alanur Cavlin; Jung-Chen Chang; Xuan Che; Costas A. Christophi; Sumeet S. Chugh; Massimo Cirillo; Samantha M. Colquhoun; Christian Kieling; Cyrus Cooper; Iuri Da Costa Leite; Lalit Dandona; Rakhi Dandona; Adrian Davis; Anand Dayama; Louisa Degenhardt; Diego De Leo; Borja Del Pozo-Cruz; Kebede Deribe; Muluken Dessalegn; Gabrielle A. DeVeber; Samath D. Dharmaratne; Uʇur Dilmen; Eric L. Ding; Rob E. Dorrington; Tim R. Driscoll; Sergey P. Ermakov; Alireza Esteghamati; Emerito Jose A. Faraon; Farshad Farzadfar; Manuela Mendonca Felicio; Seyed-Mohammad Fereshtehnejad; Graça Maria Ferreira De Lima; Mohammad H. Forouzanfar; Elisabeth B. França; Lynne Gaffikin; Ketevan Gambashidze; Fortune G. Gankpe; Ana Cristina Garcia; Johanna M. Geleijnse; Katherine B. Gibney; Maurice Giroud; Elizabeth L. Glaser; Ketevan Goginashvili; Philimon Gona; Dinorah González-Castell; Atsushi Goto; Hebe N. Gouda; Harish C. Gugnani; Rahul Gupta; Rajeev Gupta; Nima Hafezi-Nejad; Randah R. Hamadeh; Mouhanad Hammami; Graeme J. Hankey; Hilda L. Harb; Rasmus Havmoeller; Simon Hay; Ileana B. Heredia Pi; Hans W. Hoek; Francis A. Mhimbira; Damian G. Hoy; Abdullatif Husseini; Bulat T. Idrisov; Kaire Innos; Manami Inoue; Kathryn H. Jacobsen; Eiman Jahangir; Sun Ha Jee; Paul N. Jensen; Vivekanand Jha; Guohong Jiang; Jost B. Jonas; Knud Juel; Edmond Kato Kabagambe; Haidong Kan; Karam; Andre Karch; Corine Kakizi Karema; Anil Kaul; Norito Kawakami; Konstantin Kazanjan; Dhruv S. Kazi; Andrew H. Kemp; Andre P. Kengne; Maia Kereselidze; Yousef S. Khader; Shams Eldin A.H. Khalifa; Ejaz A. Khan; Young-Ho Khang; Luke Knibbs; Yoshihiro Kokubo; Soewarta Kosen; Barthelemy Kuate Defo; Chanda Kulkarni; Veena S. Kulkarni; G Anil Kumar; Kaushalendra Kumar; Ravi B. Kumar; Gene F. Kwan; Taavi Lai; Ratilal Lalloo; Hilton Lam; Van C. Lansingh; Anders Larsson; Jong-Tae Lee; James Leigh; Mall Leinsalu; Ricky Leung; Xiaohong Li; Yichong Li; Yongmei Li; Juan Liang; Xiaofeng Liang; Stephen Lim; Hsien-Ho Lin; Steven E. Lipshultz; Shiwei Liu; Yang Liu; Belinda K. Lloyd; Stephanie J. London; Paulo A. Lotufo; Jixiang Ma; Stefan Ma; Vasco Manuel Pedro Machado; Nana Kwaku Mainoo; Marek Majdan; Christopher C. Mapoma; Wagner Marcenes; Melvin B. Marzan; Amanda J. Mason-Jones; Man Mohan Mehndiratta; Fabiola Mejia-Rodriguez; Ziad A. Memish; Walter Mendoza; Ted R. Miller; Edward J. Mills; Ali H. Mokdad; Glen L. Mola; Lorenzo Monasta; Jonathan De La Cruz Monis; Julio Cesar Montañez Hernandez; Ami R. Moore; Maziar Moradi-Lakeh; Rintaro Mori; Ulrich O. Mueller; Mitsuru Mukaigawara; Aliya Naheed; Kovin S. Naidoo; Devina Nand; Vinay Nangia; Denis Nash; Chakib Nejjari; Robert G. Nelson; Sudan P. Neupane; Charles R. Newton; Marie Ng; Mark J. Nieuwenhuijsen; Muhammad I. Nisar; Sandra Nolte; Ole F. Norheim; Luke Nyakarahuka; In Hwan Oh; Takayoshi Ohkubo; Bolajoko O. Olusanya; Saad B. Omer; John Nelson Opio; Orish Ebere Orisakwe; Jeyaraj D. Pandian; Christina Papachristou; Jae-Hyun Park; Angel J. Paternina Caicedo; Scott B. Patten; Vinod K. Paul; Boris I. Pavlin; Neil Pearce; David M. Pereira; Konrad Pesudovs; Max Petzold; Dan Poenaru; Guilherme V. Polanczyk; Suzanne Polinder; Dan Pope; Farshad Pourmalek; Dima Qato; Quistberg; Anwar Rafay; Kazem Rahimi; Vafa Rahimi-Movaghar; Sajjad Ur Rahman; Murugesan Raju; Saleem M. Rana; Amany Refaat; Luca Ronfani; Nobhojit Roy; Tania Georgina Sánchez Pimienta; Mohammad Ali Sahraian; Joshua A. Salomon; Uchechukwu Sampson; Itamar S. Santos; Monika Sawhney; Felix Sayinzoga; Ione J.C. Schneider; Austin E. Schumacher; David C. Schwebel; Soraya Seedat; Sadaf G. Sepanlou; Edson E. Servan-Mori; Marina Shakh-Nazarova; Sara Sheikhbahaei; Kenji Shibuya; Hwashin Hyun Shin; Ivy Shiue; Inga D. Sigfusdottir; Donald H. Silberberg; Andrea P. Silva; Jasvinder A. Singh; Vegard Skirbekk; Karen Sliwa; Sergey S. Soshnikov; Luciano A. Sposato; Chandrashekhar T. Sreeramareddy; Konstantinos Stroumpoulis; Lela Sturua; Bryan L. Sykes; Karen M. Tabb; Roberto Tchio Talongwa; Feng Tan; Carolina Maria Teixeira; Eric Yeboah Tenkorang; Abdullah Sulieman Terkawi; Andrew L. Thorne-Lyman; David L. Tirschwell; Charles D.A. Wolfe; Bach X. Tran; Miltiadis K. Tsilimbaris; Uche S. Uchendu; Kingsley N. Ukwaja; Eduardo A. Undurraga; Selen B. Uzun; Andrew J. Vallely; Coen H. Van Gool; Tommi J. Vasankari; Monica S. Vavilala; Narayanaswamy Venketasubramanian; Salvador Villalpando; Francesco S. Violante; Vasiliy Victorovich Vlassov; Theo Vos; Stephen Waller; Haidong Wang; Linhong Wang; XiaoRong Wang; Yanping Wang; Scott Weichenthal; Elisabete Weiderpass; Robert G. Weintraub; Ronny Westerman; James D. Wilkinson; Solomon M. Woldeyohannes; John Q. Wong; Muluemebet Abera Wordofa; Gelin Xu; Yang C. Yang; Yuichiro Yano; Gokalp K. Yentur; Paul Yip; Naohiro Yonemoto; Seok-Jun Yoon; Mustafa Younis; Chuanhua Yu; Kim Yun Jin; Maysaa El Sayed Zaki; Yong Zhao; Yingfeng Zheng; Maigeng Zhou; Jun Zhu; Xiao Nong Zou; Alan D. Lopez; Mohsen Naghavi; Christopher J.L. Murray; Rafael Lozano
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Understanding Crohn's disease through genetics
Cell Cycle, ISSN: 15514005 15384101
Aditya Murthy; Menno Van Lookeren Campagne
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Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Lan Wang; Mark S. Stanley; Jason Boggs; Terry Crawford; Brandon Bravo; Anthony M. Giannetti; Seth F. Harris; Steven Magnuson; Jim Nonomiya; Stephen Schmidt; Ping Wu; Weilan Ye; Stephen Gould; Lesley J. Murray; Chudi O. Ndubaku; Huifen Chen
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Detection of residual biocides in antibody drug conjugates for ImmunoPET imaging
Analytical Methods, ISSN: 17599679 17599660
Colin D. Medley; Jason Gruenhagen; Peter M. Yehl; Nik P. Chetwyn
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Structures of neutrophil serine protease 4 reveal an unusual mechanism of substrate recognition by a trypsin-fold protease
Structure, ISSN: 18784186 09692126
S. Jack Lin; Ken Dong; Eigenbrot; Menno Van Lookeren Campagne; Daniel Kirchhofer
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Shining LIGHT on functional promiscuity in the TNF and TNFR superfamilies
Structure, ISSN: 18784186 09692126
Daniel M. Whalen; Sarah G. Hymowitz
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Challenges with overall survival as an endpoint for efficacy assessment in first line metastatic breast cancer randomized controlled clinical trials and the investigation of truncated overall survival as an alternative endpoint
Memo - Magazine of European Medical Oncology, ISSN: 18655076 18655041
Neate; Alexander Strasak; Hans Ulrich Burger; Barbara Tong; Lee D. Kaiser
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Biomarker analyses from a placebo-controlled phase II study evaluating erlotinib±onartuzumab in advanced non-small cell lung cancer: MET expression levels are predictive of patient benefit
Clinical Cancer Research, ISSN: 10780432
Koeppen; Wei Yu; Jiping Zha; Ajay Pandita; Elicia M. Penuel; Linda Rangell; Rajiv Raja; Sankar Mohan; Rajesh Patel; Rupal Desai; Ling Fu; An Do; Vaishali Parab; Xiaoling Xia; Thomas Januario; Sharianne G. Louie; Ellen H. Filvaroff; David S. Shames; Ignacio I. Wistuba; Marina Lipkind; Jenny Huang; Mirella Lazarov; Vanitha Ramakrishnan; Lukas Amler; See Phan; Premal Patel; Amy Peterson; Robert Yauch
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Genetically engineered knock-in and conditional knock-in mouse models of cancer
Cold Spring Harbor Protocols, ISSN: 15596095 19403402
Amy Rappaport; Leisa Johnson
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Stable-isotope-labeled histone peptide library for histone post-translational modification and variant quantification by mass spectrometry
Molecular and Cellular Proteomics, ISSN: 15359484 15359476
Shu Lin; Samuel Wein; Michelle Gonzales-Cope; Gabriel L. Otte; Zuo-Fei Yuan; Leila Afjehi-Sadat; Tobias Maile; Shelley L. Berger; John Rush; Jennie R. Lill; David Arnott; Benjamin A. Garcia
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Rapid UHPLC-HRMS peptide mapping for monoclonal antibodies
American Pharmaceutical Review, ISSN: 10998012
Nisana Andersen; Lisa Vampola; Rashmi Jain; Melissa Alvarez; Scott Chamberlain; Amy Hilderbrand
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Trastuzumab emtansine in human epidermal growth factor receptor 2-positive metastatic breast cancer: An integrated safety analysis
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Diéras; Nadia Harbeck; G. Thomas Budd; Joel K. Greenson; Ellie Guardino; Meghna Samant; Nataliya Chernyukhin; Melanie Smitt; Ian E. Krop
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Framework selection can influence pharmacokinetics of a humanized therapeutic antibody through differences in molecule charge
mAbs, ISSN: 19420870 19420862
Bing Li; Devin B. Tesar; C. Andrew Boswell; Hendry S. Cahaya; Anne Wong; Jianhuan Zhang; Meng; Eigenbrot; Homer Pantua; Jingyu Diao; Sharookh B. Kapadia; Rong Deng; Robert F. Kelley
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Assessing the discordance rate between local and central HER2 testing in women with locally determined HER2-negative breast cancer
Cancer, ISSN: 10970142 0008543X
Peter A. Kaufman; Kenneth J. Bloom; Howard A. Burris; Julie Gralow; Musa Mayer; Pegram; Hope S. Rugo; Sandra M. Swain; Denise A. Yardley; Miu Chau; Deepa Lalla; Bongin Yoo; Melissa Brammer; Charles L. Vogel
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Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity
Blood, ISSN: 15280020 00064971
Catalina Lee-Chang; Monica Bodogai; Kanako Moritoh; Purevdorj Baljinnyam Olkhanud; Andrew C. Chan; Michael Croft; Julie A. Mattison; Peter Johannes Holst; Ronald E. Gress; Luigi G. Ferrucci; Frances T. Hakim; Arya Biragyn
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Whole genome sequencing and analysis of plant growth promoting bacteria isolated from the rhizosphere of plantation crops coconut, cocoa and arecanut
PLoS ONE, ISSN: 19326203
Alka Gupta; Murali Gopal; George Thomas; Vinu Manikandan; John Gajewski; George Thomas; Somasekar Seshagiri; Stephan C. Schuster; Preeti Rajesh; Ravi Gupta
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Accurate analysis of boronic pinacol esters using low residual silanol silica based reversed phase HPLC
Journal of Liquid Chromatography and Related Technologies, ISSN: 1520572X 10826076
Archana Kumar; Tania Ng; Sushant Malhotra; Jason Gruenhagen; Larry Wigman
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Relationships between computer-extracted mammographic texture pattern features and BRCA1/2 mutation status: A cross-sectional study
Breast Cancer Research, ISSN: 1465542X 14655411
Gretchen L. Gierach; Hui Li; Jennifer T. Loud; Mark H. Greene; Catherine K. Chow; Li Lan; Sheila A. Prindiville; Jennifer Eng-Wong; Peter W. Soballe; Claudia Giambartolomei; Phuong L. Mai; Claudia E. Galbo; Kathryn Nichols; Kathleen A. Calzone; Olufunmilayo I. Olopade; Mitchell H. Gail; Maryellen L. Giger
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Similar prevalence of low-abundance drug-resistant variants in treatment-naive patients with genotype 1a and 1b hepatitis C virus infections as determined by ultradeep pyrosequencing
PLoS ONE, ISSN: 19326203
Severine Margeridon-Thermet; Sophie Le Pogam; Lewyn Li; Tommy F. Liu; Nancy Shulman; Robert W. Shafer; Nájera
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Gtpbp2 is required for BMP signaling and mesoderm patterning in Xenopus embryos
Developmental Biology, ISSN: 1095564X 00121606
Arif Kirmizitas; William Q. Gillis; Haitao Zhu; Gerald H. Thomsen
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Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Peter Dragovich; Benjamin P. Fauber; Jason Boggs; Jinhua Chen; Laura B. Corson; Charles Z. Ding; Eigenbrot; Hongxiu Ge; Anthony M. Giannetti; Thomas Hunsaker; Sharada Labadie; Chiho Li; Yichin Liu; Yingchun Liu; Shuguang Ma; Shiva Malek; David Peterson; Keith Pitts; Hans E. Purkey; Kirk D. Robarge; Laurent Salphati; Steve Sideris; Ultsch; Erica Vanderporten; Jing Wang; Binqing Wei; Qing Xu; Ivana Yen; Qin Yue; Huihui Zhang; Xuying Zhang; Aihe Zhou
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Cutting edge: RIPK1 kinase inactive mice are viable and protected from TNF-Induced necroptosis in vivo
Journal of Immunology, ISSN: 15506606 00221767
Apostolos Polykratis; Nicole Hermance; Matija Zelic; Justine Roderick; Chun Kim; Trieu-My Van; Thomas H. Lee; Francis K.M. Chan; Manolis Pasparakis; Michelle A. Kelliher
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Reduction in lipophilicity improved the solubility, plasma-protein binding, and permeability of tertiary sulfonamide RORc inverse agonists
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Benjamin P. Fauber; Olivier René; Gladys De Leon Boenig; Brenda Burton; Yuzhong Deng; Celine Eidenschenk; Christine Everett; Alberto Gobbi; Sarah G. Hymowitz; Adam R. Johnson; Hank La; Marya Liimatta; Peter Lockey; Maxine Norman; Wenjun Ouyang; Weiru Wang; Harvey Wong
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Characterization of asparagine 330 deamidation in an Fc-fragment of IgG1 using cation exchange chromatography and peptide mapping
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, ISSN: 1873376X 15700232
Taylor Zhang; Jennifer Hu; Amanda L. Pace; Wong; Y. John Wang; Kao
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Randomized phase Ib/II trial of rilotumumab or ganitumab with panitumumab versus panitumumab alone in patients with wild-type KRAS metastatic colorectal cancer
Clinical Cancer Research, ISSN: 15573265 10780432
Eric Van Cutsem; Cathy Eng; Elzbieta Nowara; Anna Swieboda-Sadlej; Niall C. Tebbutt; Edith Mitchell; Irina Davidenko; Joe Stephenson; Elena Elez; Hans Prenen; Hongjie Deng; Rui Tang; Ian McCaffery; Kelly S. Oliner; Lisa Chen; Jennifer Gansert; Elwyn Loh; Dominic Smethurst; Tabernero
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Lymph node fibroblastic reticular cell transplants show robust therapeutic efficacy in high-mortality murine sepsis
Science Translational Medicine, ISSN: 19466242 19466234
Anne L. Fletcher; Jessica S. Elman; Jillian L. Astarita; Ryan Murray; Nima Saeidi; Joshua D'Rozario; Konstantin Knoblich; Flavian D. Brown; Frank A Schildberg; Janice M. Nieves; Tracy S. P. Heng; Richard L. Boyd; Shannon J. Turley; Biju Parekkadan
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Temperature dependence of the complexation mechanism of celecoxib and hydroxyl-β-cyclodextrin in aqueous solution
Pharmaceutics, ISSN: 19994923
Po-Chang Chiang; Yue Shi; Yong Cui
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Structurally diverse MDM2-p53 antagonists act as modulators of MDR-1 function in neuroblastoma
British Journal of Cancer, ISSN: 15321827 00070920
Lindi Chen; Zhao; Halliday; Berry; Raphaël F. Rousseau; Steven A. Middleton; Gwen L. Nichols; Del Bello; Piergentili; David R. Newell; John Lunec; Deborah A. Tweddle
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A phase IIa dose-finding and safety study of first-line pertuzumab in combination with trastuzumab, capecitabine and cisplatin in patients with HER2-positive advanced gastric cancer
British Journal of Cancer, ISSN: 15321827 00070920
Yoon-Koo Kang; Rha; Tassone; Barriuso; Ron Yu; Szado; Amit Garg; Bang
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Drug resistance via feedback activation of stat3 in oncogene-addicted cancer cells
Cancer Cell, ISSN: 18783686 15356108
Ho-June Lee; Guanglei Zhuang; Yi Cao; Pan Du; Hyo-Jin Kim; Jeffrey Settleman
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MBASED: Allele-specific expression detection in cancer tissues and cell lines
Genome Biology, ISSN: 1474760X 14747596
Oleg Mayba; Houston N. Gilbert; Jinfeng Liu; Matthias Peter; Suchit Jhunjhunwala; Zhaoshi Jiang; Colin K. Watanabe; Zemin Zhang
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Dimerization of the kinase ARAF promotes MAPK pathway activation and cell migration
Science Signaling, ISSN: 19379145 19450877
Juliane Mooz; Tripat Kaur Oberoi-Khanuja; Gregory S. Harms; Weiru Wang; Bijay S. Jaiswal; Somasekar Seshagiri; Ritva Tikkanen; Krishnaraj Rajalingam
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Analytical strategies for genotoxic impurities in the pharmaceutical industry
American Pharmaceutical Review, ISSN: 10998012
Venkatramani; Mohammad Al-Sayah
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Investigation of excipient compatibility and associated degradations for the formulation development of a small molecule pharmaceutical compound
American Pharmaceutical Review, ISSN: 10998012
Jane Li; Hong Lin; Christine Gu; Priscilla Mantik; Stefanie Gee; Peter M. Yehl
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