Scientists / Publications

Publications

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DISPLAYING 801 - 850 OF 15185 RESULTS

Determination of BET Specific Surface Area of Hydrate-Anhydrate Systems Susceptible to Phase Transformation Using Inverse Gas Chromatography
AAPS PharmSciTech,
Minhthi Bui; Karthik Nagapudi; Paroma Chakravarty
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Disease-associated oligodendrocyte responses across neurodegenerative diseases
Cell Reports, ISSN: 22111247
Shristi Pandey; Kimberle Shen; Seung-Hye Lee; Yun-An A. Shen; Yuanyuan Wang; Marcos Otero-Garcia; Natalya Kotova; Stephen T. Vito; Benjamin I. Laufer; Dwight F. Newton; Mitchell G. Rezzonico; Jesse E. Hanson; Joshua S. Kaminker; Christopher J. Bohlen; Tracy J. Yuen; Brad A. Friedman
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Disease-associated oligodendrocyte responses across neurodegenerative diseases
Cell Reports,
Shristi Pandey; Kimberle Shen; Seung-Hye Lee; Yun-An A. Shen; Yuanyuan Wang; Marcos Otero-Garcia; Natalya Kotova; Stephen T. Vito; Benjamin I. Laufer; Dwight F. Newton; Mitchell G. Rezzonico; Jesse E. Hanson; Joshua S. Kaminker; Christopher J. Bohlen; Tracy J. Yuen; Brad A. Friedman
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EHMT2 methyltransferase governs cell identity in the lung and is required for KRAS G12D tumor development and propagation
eLife, ISSN: 2050084X
Ariel Pribluda; Anneleen Daemen; Anthony Lima; Xi Wang; Marc Hafner; Chungkee Poon; Zora Modrusan; Anand K. Katakam; Oded Foreman; Jeffrey Eastham; Jeffrey Hung; Benjamin Haley; Julia T. Garcia; Erica L. Jackson; Melissa Junttila
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Development of Dual Practical Manufacturing Routes to Cognate Pyrrolobenzodiazepine-Based Linker-Drugs
Organic Process Research and Development, ISSN: 1520586X 10836160
Stefan G. Koenig; Remy Angelaud; Christopher M. Crittenden; Kenji Kurita; David J. Russell; Jean-Francois Marcoux; Thomas Matt; Francis Gosselin
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Importance of Green and Sustainable Chemistry in the Chemical Industry
Organic Process Research and Development, ISSN: 1520586X 10836160
Juan Colberg; King Kuok Hii; Stefan G. Koenig
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EHMT2 methyltransferase governs cell identity in the lung and is required for KRAS G12D tumor development and propagation
eLife,
Ariel Pribluda; Anneleen Daemen; Anthony Lima; Xi Wang; Marc Hafner; Chungkee Poon; Zora Modrusan; Anand K. Katakam; Oded Foreman; Jeffrey Eastham; Jeffrey Hung; Benjamin Haley; Julia T. Garcia; Erica L. Jackson; Melissa Junttila
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Single-cell analysis reveals clonally expanded tumor-associated CD57 +CD8 T cells are enriched in the periphery of patients with metastatic urothelial cancer responding to PD-L1 blockade
Journal for ImmunoTherapy of Cancer, ISSN: 20511426
Michael Fehlings; Leesun Kim; Xiangnan Guan; Kobe Yuen; Alireza Tafazzol; Shomyseh Sanjabi; Oliver A. Zill; Deepali Rishipathak; Andrew Wallace; Alessandra Nardin; Siming Ma; Ana Milojkovic; Evan W. Newell; Sanjeev Mariathasan; Mahesh Yadav
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Engineered Cytochrome P450-Catalyzed Oxidative Biaryl Coupling Reaction Provides a Scalable Entry into Arylomycin Antibiotics
Journal of the American Chemical Society, ISSN: 15205126 00027863
Carmela Molinaro; Yukie Kawasaki; George Wanyoike; Taiki Nishioka; Tsuyoshi Yamamoto; Snedecor; Sarah J. Robinson; Francis Gosselin
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The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotides
Journal of Chromatography A, ISSN: 18733778 00219673
Honorine Lardeux; Alexandre Goyon; Kelly Zhang; Jennifer M Nguyen; Matthew A Lauber; Davy Guillarme; Valentina D'Atri
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Analytical techniques for characterizing diastereomers of phosphorothioated oligonucleotides
Journal of Chromatography A, ISSN: 18733778 00219673
Tao Chen; Shijia Tang; Yige Fu; José G. Napolitano; Kelly Zhang
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The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotides
Journal of Chromatography A, ISSN: 00219673
Honorine Lardeux; Alexandre Goyon; Kelly Zhang; Jennifer M Nguyen; Matthew A Lauber; Davy Guillarme; Valentina D'Atri
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Liquid chromatography coupled with photodiode array and a multivariate curve resolution – Alternating least square algorithm for identification and quantification of co-eluting impurities in pharmaceutical analysis
Journal of Chromatography A, ISSN: 18733778 00219673
Davide Vecchietti; Akira Nishio; Yuichiro Fujita; Takeshi Yoshida; Toshinobu Yanagisawa; Dawen Kou
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Liquid chromatography coupled with photodiode array and a multivariate curve resolution – Alternating least square algorithm for identification and quantification of co-eluting impurities in pharmaceutical analysis
Journal of Chromatography A, ISSN: 00219673
Davide Vecchietti; Akira Nishio; Yuichiro Fujita; Takeshi Yoshida; Toshinobu Yanagisawa; Dawen Kou
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First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors
Clinical Cancer Research, ISSN: 15573265 10780432
Tae Won Kim; Howard A. Burris; Maria J. de Miguel Luken; Pishvaian; Bang; Michael S. Gordon; Ahmad Awada; D. Ross Camidge; F. Stephen Hodi; Grant A. McArthur; Miller; Andrés Cervantes; Laura Q.M. Chow; Alexander M. Lesokhin; Annemie Rutten; Mario Sznol; Deepali Rishipathak; Shang-Chiung Chen; Stefanich; Tony Pourmohamad; Maria Anderson; Jeong Kim; Mahrukh Huseni; Ina Rhee; Siu
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Monitoring multiple quality attributes of a complex Fc-fusion protein during cell culture production processes by mD-LC-MS peptide mapping
Talanta, ISSN: 00399140
Julien Camperi; Sanket Dahotre; Davy Guillarme; Cinzia Stella
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First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors
Clinical Cancer Research, ISSN: 10780432
Tae Won Kim; Howard A. Burris; Maria J. de Miguel Luken; Pishvaian; Bang; Michael S. Gordon; Ahmad Awada; D. Ross Camidge; F. Stephen Hodi; Grant A. McArthur; Miller; Andrés Cervantes; Laura Q.M. Chow; Alexander M. Lesokhin; Annemie Rutten; Mario Sznol; Deepali Rishipathak; Shang-Chiung Chen; Stefanich; Tony Pourmohamad; Maria Anderson; Jeong Kim; Mahrukh Huseni; Ina Rhee; Siu
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Attached Nitrogen Test by 13C-14N Solid-State NMR Spectroscopy for the Structure Determination of Heterocyclic Isomers
Organic Letters, ISSN: 15237052 15237060
Rick W. Dorn; Brendan J. Wall; Sarah B. Ference; Sean R. Norris; Joseph W. Lubach; Aaron J. Rossini; Brett VanVeller
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Immune microenvironment characteristics in multiple myeloma progression from transcriptome profiling
Frontiers in Oncology, ISSN: 2234943X
Jin Wang; Yi Hu; Habib Hamidi; Cedric Dos Santos; Jingyu Zhang; Elizabeth A. Punnoose; Wenjin Li
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The “η-sweet-spot” (ηmax) in liquid-assisted mechanochemistry: polymorph control and the role of a liquid additive as either a catalyst or an inhibitor in resonant acoustic mixing (RAM)
Faraday Discussions, ISSN: 13645498 13596640
Lori Gonnet; Tristan H. Borchers; Cameron B. Lennox; Jogirdas Vainauskas; Yong Teoh; Hatem M. Titi; Christopher J. Barrett; Stefan G. Koenig; Karthik Nagapudi; Tomislav Friščić
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mRNA Display and Its Growing Potential in the Discovery of de Novo Therapeutic Peptide Candidates
ACS Symposium Series, ISSN: 19475918 00976156
Christina Helmling; Christian N. Cunningham
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mRNA Display and Its Growing Potential in the Discovery of de Novo Therapeutic Peptide Candidates
ACS Symposium Series, ISSN: 00976156
Christina Helmling; Christian N. Cunningham
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Preface
ACS Symposium Series, ISSN: 19475918 00976156
Swapnil V. Ghodge; Kaustav Biswas; Andrei A. Golosov
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NMR Spectroscopy for Studying Peptide Conformations and Cell Permeability
ACS Symposium Series, ISSN: 00976156
Kaustav Biswas; Andrei A. Golosov; Emel Adaligil; Wayne J. Fairbrother
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NMR Spectroscopy for Studying Peptide Conformations and Cell Permeability
ACS Symposium Series, ISSN: 19475918 00976156
Kaustav Biswas; Andrei A. Golosov; Emel Adaligil; Wayne J. Fairbrother
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Chiral Amines via Enantioselective π-Allyliridium-C,O-Benzoate-Catalyzed Allylic Alkylation: Student Training via Industrial-Academic Collaboration
Accounts of Chemical Research,
Craig E. Stivala; Jason R. Zbieg; Peng Liu; Michael J. Krische
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VERONICA: Randomized Phase II Study of Fulvestrant and Venetoclax in ER-Positive Metastatic Breast Cancer Post-CDK4/6 Inhibitors - Efficacy, Safety, and Biomarker Results
Clinical Cancer Research,
Geoffrey J. Lindeman; Tharu M. Fernando; Rebecca Bowen; Katarzyna J. Jerzak; Xinni Song; Thomas Decker; Frances Boyle; Steven McCune; Anne Armstrong; Catherine Shannon; Gianfilippo Bertelli; Ching-Wei Chang; Rupal Desai; Kushagra Gupta; Wilson; Aulde Flechais; Aditya Bardia
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Chiral Amines via Enantioselective π-Allyliridium-C,O-Benzoate-Catalyzed Allylic Alkylation: Student Training via Industrial-Academic Collaboration
Accounts of Chemical Research, ISSN: 15204898
Craig E. Stivala; Jason R. Zbieg; Peng Liu; Michael J. Krische
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Chiral Amines via Enantioselective π-Allyliridium- C, O-Benzoate-Catalyzed Allylic Alkylation: Student Training via Industrial-Academic Collaboration
Accounts of Chemical Research, ISSN: 15204898 00014842
Craig E. Stivala; Jason R. Zbieg; Peng Liu; Michael J. Krische
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Untreated bleeds in people with hemophilia A in a noninterventional study and intrapatient comparison after initiating emicizumab in HAVEN 1–3
Research and Practice in Thrombosis and Haemostasis, ISSN: 24750379
Michael U. Callaghan; Elina Asikanius; Michaela Lehle; Johannes Oldenburg; Johnny N. Mahlangu; Marianne Uguen; Sammy Chebon; Kruse-Jarres; Jiménez-Yuste; Midori Shima; Peter C. Trask; Kempton; Craig Kessler; Gallia Levy; Flora Peyvandi
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VERONICA: Randomized Phase II Study of Fulvestrant and Venetoclax in ER-Positive Metastatic Breast Cancer Post-CDK4/6 Inhibitors - Efficacy, Safety, and Biomarker Results
Clinical Cancer Research, ISSN: 15573265 10780432
Geoffrey J. Lindeman; Tharu M. Fernando; Rebecca Bowen; Katarzyna J. Jerzak; Xinni Song; Thomas Decker; Frances Boyle; Steven McCune; Anne Armstrong; Catherine Shannon; Gianfilippo Bertelli; Ching-Wei Chang; Rupal Desai; Kushagra Gupta; Wilson; Aulde Flechais; Aditya Bardia
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Pharmacokinetics and Exposure-Response Analysis of Venetoclax + Obinutuzumab in Chronic Lymphocytic Leukemia: Phase 1b Study and Phase 3 CLL14 Trial
Advances in Therapy, ISSN: 18658652 0741238X
Divya Samineni; Leonid Gibiansky; Wang; Shweta Vadhavkar; Richa Rajwanshi; Tandon; Arijit Sinha; Othman Al-Sawaf; Kirsten Fischer; Michael Hallek; Ahmed Hamed Salem; Chunze Li; Dale Miles
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Omalizumab treatment reduces asthma exacerbations regardless of airway bronchodilator reversibility
Journal of Allergy and Clinical Immunology: In Practice, ISSN: 22132198
Samuel DeLeon; Franco Barsanti; Cécile T.J. Holweg; Bongin Yoo; Blaine Creasy; Michael E. Wechsler
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Pharmacokinetics and Exposure-Response Analysis of Venetoclax + Obinutuzumab in Chronic Lymphocytic Leukemia: Phase 1b Study and Phase 3 CLL14 Trial
Advances in Therapy, ISSN: 18658652 0741238X
Divya Samineni; Leonid Gibiansky; Bei Wang; Shweta Vadhavkar; Richa Rajwanshi; Tandon; Arijit Sinha; Othman Al-Sawaf; Kirsten Fischer; Michael Hallek; Ahmed Hamed Salem; Chunze Li; Dale Miles
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Erratum to Gene Set Enrichment Analyses Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy. Am J Ophthalmol 2022;233:111-123 (American Journal of Ophthalmology (2022) 233 (111–123), (S0002939421003366), (10.1016/j.ajo.2021.06.014))
American Journal of Ophthalmology, ISSN: 18791891 00029394
Lucia Sobrin; Gayatri Susarla; Lynn K. Stanwyck; John M. Rouhana; Ashley Li; Samuela Pollack; Robert P. Igo; Richard A. Jensen; Xiaohui Li; Maggie C.Y. Ng; Albert V Smith; Jane Z. Kuo; Kent D. Taylor; Barry I. Freedman; Donald W. Bowden; Alan Penman; Ching J. Chen; Jamie E. Craig; Sharon G. Adler; Emily Y. Chew; Mary Frances Cotch; Brian L. Yaspan; Paul Mitchell; Jie Jin Wang; Barbara E.K. Klein; Tien Y. Wong; Jerome I. Rotter; Kathryn Burdon; Sudha K. Iyengar; Ayellet V. Segrè
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Applications of Model-Based Meta-Analysis in Drug Development
Pharmaceutical Research, ISSN: 1573904X 07248741
Phyllis Chan; Kirill Peskov; Xuyang Song
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Comment on A Implication of baseline levels and early changes of C-reactive protein for subsequent clinical outcomes of patients with rheumatoid arthritis treated with tocilizumab'
Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
Attila Pethoe-Schramm; Jenny Devenport; William Reiss
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Application of Empirical Scalars to Enable Early Prediction of Human Hepatic Clearance Using in Vitro-In Vivo Extrapolation in Drug Discovery: An Evaluation of 173 Drugs
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Robert Jones; Christian Leung; Jae H. Chang; Suzanne Brown; Ning Liu; Zhengyin Yan; Jane R. Kenny; Broccatelli
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Safety and efficacy of mosunetuzumab, a bispecific antibody, in patients with relapsed or refractory follicular lymphoma: a single-arm, multicentre, phase 2 study
The Lancet Oncology, ISSN: 14702045
Lihua E. Budde; Laurie H. Sehn; Matthew Matasar; Stephen J. Schuster; Sarit E. Assouline; Pratyush Giri; Kuruvilla; Miguel Canales; Sascha Dietrich; Keith Fay; Matthew Ku; Loretta J. Nastoupil; Chan Yoon Cheah; Michael C. Wei; Shen Yin; Chi-Chung Li; Huang Huang; Antonia Kwan; Elicia M. Penuel; Nancy L. Bartlett
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Untreated bleeds in people with hemophilia A in a noninterventional study and intrapatient comparison after initiating emicizumab in HAVEN 1–3
Research and Practice in Thrombosis and Haemostasis,
Michael U. Callaghan; Elina Asikanius; Michaela Lehle; Johannes Oldenburg; Johnny N. Mahlangu; Marianne Uguen; Sammy Chebon; Kruse-Jarres; Jiménez-Yuste; Midori Shima; Peter C. Trask; Kempton; Craig Kessler; Gallia Levy; Flora Peyvandi
View on Scopus
A Phase II Study of Ziv-Aflibercept in Patients With Advanced Extrapancreatic Neuroendocrine Tumors
Pancreas, ISSN: 15364828 08853177
Kimberly Perez; Matthew H. Kulke; Nora K. Horick; Eileen Regan; Christopher Graham; Samantha Scheutz; Danielle Stonely; Peter C. Enzinger; Charles Fuchs; Jill N. Allen; Andrea C. Enzinger; Jeffrey W. Clark; Jennifer A. Chan
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Single-cell analysis reveals clonally expanded tumor-associated CD57+ CD8 T cells are enriched in the periphery of patients with metastatic urothelial cancer responding to PD-L1 blockade
Journal for ImmunoTherapy of Cancer, ISSN: 20511426
Michael Fehlings; Leesun Kim; Xiangnan Guan; Kobe Yuen; Alireza Tafazzol; Shomyseh Sanjabi; Oliver A. Zill; Deepali Rishipathak; Andrew Wallace; Alessandra Nardin; Siming Ma; Ana Milojkovic; Evan W. Newell; Sanjeev Mariathasan; Mahesh Yadav
View on Scopus
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment
Nature Genetics, ISSN: 15461718 10614036
William L. Hwang; Karthik A. Jagadeesh; Jimmy A. Guo; Hannah I. Hoffman; Payman Yadollahpour; Jason Reeves; Rahul Mohan; Eugene Drokhlyansky; Nicholas Van Wittenberghe; Orr Ashenberg; Samouil L. Farhi; Denis Schapiro; Prajan Divakar; Eric M. Miller; Daniel R. Zollinger; George Eng; Jason M. Schenkel; Jennifer Su; Carina Shiau; Patrick Yu; William A. Freed-Pastor; Domenic Abbondanza; Arnav Mehta; Joshua Gould; Conner Lambden; Caroline B. M. Porter; Alexander Tsankov; Danielle Dionne; Julia Waldman; Michael S. Cuoco; Lan Nguyen; Toni M. Delorey; Devan Phillips; Jaimie L. Barth; Marina Kem; Clifton Rodrigues; Debora Ciprani; Jorge Roldan; Piotr Zelga; Vjola Jorgji; Jonathan Chen; Zackery Ely; Daniel Zhao; Kit Fuhrman; Robin Fropf; Joseph M. Beechem; Jay S. Loeffler; Ryan; Colin D. Weekes; Cristina R. Ferrone; Motaz Qadan; Martin J. Aryee; Rakesh K. Jain; Donna S. Neuberg; Jennifer Y. Wo; Theodore S. Hong; Ramnik J. Xavier; Andrew J. Aguirre; Orit Rozenblatt-Rosen; Mari Mino-Kenudson; Carlos Fernandez-del Castillo; Andrew S. Liss; David T. Ting; Tyler Jacks; Aviv Regev
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Author Correction: LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding (Nature Biotechnology, (2021), 39, 12, (1556-1562), 10.1038/s41587-021-00966-9)
Nature Biotechnology, ISSN: 15461696 10870156
Kerstin U. Ludwig; Ricarda M. Schmithausen; David Li; Max L. Jacobs; Ronja Hollstein; Katja Blumenstock; Jana Liebing; Mikołaj Słabicki; Amir Ben-Shmuel; Ofir Israeli; Shay Weiss; Thomas S. Ebert; Nir Paran; Wibke Rüdiger; Gero Wilbring; David Feldman; Bärbel Lippke; Nina Ishorst; Lara M. Hochfeld; Eva C. Beins; Ines H. Kaltheuner; Maximilian Schmitz; Aliona Wöhler; Manuel Döhla; Esther Sib; Marius Jentzsch; Eva-Maria C. Moench; Jacob D. Borrajo; Jonathan Strecker; Julia Reinhardt; Brian Cleary; Matthias Geyer; Michael Hölzel; Rhiannon Macrae; Markus M. Nöthen; Per Hoffmann; Martin Exner; Aviv Regev; Feng Zhang; Jonathan L. Schmid-Burgk
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Patient Preference and Treatment Satisfaction with a Port Delivery System for Ranibizumab vs Intravitreal Injections in Patients with Neovascular Age-Related Macular Degeneration: A Randomized Clinical Trial
JAMA Ophthalmology, ISSN: 21686173 21686165
Margaret A. Chang; Audrey Kapre; Derrick Kaufman; David Kardatzke; Melvin D. Rabena; Shienal Patel; Ashwini Bobbala; Shamika Gune; Anne Fung; Gene Wallenstein
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Effects of inhaled JAK inhibitor GDC-4379 on exhaled nitric oxide and peripheral biomarkers of inflammation
Pulmonary Pharmacology and Therapeutics, ISSN: 15229629 10945539
Hubert Chen; Rebecca Kunder; Yixuan Zou; Tracy Staton; Rui Zhu; Joshua Galanter; Hallam Gugelmann; Ryan Owen; Michele A. Grimbaldeston; Joanna K. Chang; Matthew Durk; Avi Eliahu; Mark S. Wilson; David F. Choy; Maria E. Wilson; Melissa Black; Marjan Doppen; Stacey Kung; Karen Oldfield; Jenny Sparks; Beasley; Irene Braithwaite
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Safety and efficacy of mosunetuzumab, a bispecific antibody, in patients with relapsed or refractory follicular lymphoma: a single-arm, multicentre, phase 2 study
The Lancet Oncology, ISSN: 14745488 14702045
Lihua E. Budde; Laurie H. Sehn; Matthew Matasar; Stephen J. Schuster; Sarit E. Assouline; Pratyush Giri; Kuruvilla; Miguel Canales; Sascha Dietrich; Keith Fay; Matthew Ku; Loretta J. Nastoupil; Chan Yoon Cheah; Michael C. Wei; Shen Yin; Chi-Chung Li; Huang Huang; Antonia Kwan; Elicia M. Penuel; Nancy L. Bartlett
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Brief Report: Safety and Antitumor Activity of Alectinib Plus Atezolizumab From a Phase 1b Study in Advanced ALK-Positive NSCLC
JTO Clinical and Research Reports, ISSN: 26663643
Dong-Wan Kim; Shirish M. Gadgeel; Scott Gettinger; Gregory J. Riely; Geoffrey R. Oxnard; Tarek Mekhail; Schmid; Afshin Dowlati; Rebecca S. Heist; Antoinette J. Wozniak; Jatinder Singh; Edward Cha; Spahn; Sai-Hong Ignatius Ou
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Macular neovascularization lesion type and vision outcomes in neovascular age-related macular degeneration: post hoc analysis of HARBOR
Graefe's Archive for Clinical and Experimental Ophthalmology, ISSN: 1435702X 0721832X
K. Bailey Freund; Giovanni Staurenghi; Jesse J. Jung; Sandrine A. Zweifel; Mariano Cozzi; Lauren Hill; Steven Blotner; Min Tsuboi; Shamika Gune
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Identification of Agitation-Induced Unfolding Events Causing Aggregation of Monoclonal Antibodies Using Hydrogen Exchange-Mass Spectrometry
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Chamalee L. D Gamage; David D. Weis; Benjamin T. Walters
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