Scientists / Publications

Publications

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DISPLAYING 8601 - 8650 OF 15656 RESULTS

Preclinical absorption, distribution, metabolism, excretion, and pharmacokinetic-pharmacodynamic modelling of N-(4-(3-((3S,4R)-1-ethyl-3- fluoropiperidine-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)-3-fluorophenyl) -2-(4-fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxamide, a novel MET kinase inhibitor
Xenobiotica, ISSN: 00498254 13665928
Bianca M. Liederer; Leonid M. Berezhkovskiy; Brian J. Dean; Victoria Dinkel; Jing Peng; Mark Merchant; Emile G. Plise; Harvey Wong; Xingrong Liu
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cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production
Cell Death and Differentiation, ISSN: 13509047 14765403
Nele Vanlangenakker; Vanden Berghe; Bogaert; Bram Laukens; Zobel; Deshayes; Domagoj Vucic; Fulda; Vandenabeele; Mathieu J.M. Bertrand
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A humanized monoclonal antibody targeting the β7 integrin selectively blocks intestinal homing of T lymphocytes
British Journal of Pharmacology, ISSN: 00071188 14765381
Stefanich; Dimitry Danilenko; Hong Wang; Sharon O'Byrne; Erickson; Thomas R. Gelzleichter; Hajime Hiraragi; Chiu; Ivelja; Surinc Er Jeet; Gadkari; Hwang; Franklin Fuh; Looney; Howell; Albert; Mercedesz Balazs; Refino; Sherman Fong; Suhasini Iyer; Marna Williams
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AVAglio: Phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme
Advances in Therapy, ISSN: 0741238X 18658652
Olivier L. Chinot; De La Motte Rouge; Moore; Zeaiter; Asha Das; Phillips; Zora Modrusan; Timothy Cloughesy
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A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target
GLIA, ISSN: 08941491 10981136
Alexander Schulte; Hauke S. Günther; Phillips; Dirk Kemming; Tobias Martens; Samir Kharbanda; Robert Soriano; Zora Modrusan; Svenja Zapf; Manfred Westphal; Katrin Lamszus
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Compliance with PET acquisition protocols for therapeutic monitoring of erlotinib therapy in an international trial for patients with non-small cell lung cancer
European Journal of Nuclear Medicine and Molecular Imaging, ISSN: 16197070
David S. Binns; Andrea Pirzkall; Wei Yu; Jason Callahan; Linda Mileshkin; Peter Conti; Andrew M. Scott; David Macfarlane; Bernard M. Fine; Rodney Hicks
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In vitro stability and compatibility of tenecteplase in central venous access devices
Hemodialysis International, ISSN: 14927535 15424758
Yvonne Lentz; Michael Joyce; Lam
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DNA markers linked to eastern filbert blight resistance in "Ratoli" hazelnut (Corylus avellana L.)
Tree Genetics and Genomes, ISSN: 16142942 16142950
Sathuvalli; Chen; Mehlenbacher; Smith
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Genetic and molecular analysis of nematode-microbe interactions
Cellular Microbiology, ISSN: 14625814 14625822
Man-Wah Tan; Michael Shapira
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Improving prescribing safety in patients with renal insufficiency in the ambulatory setting: The Drug Renal Alert Pharmacy (DRAP) program
Pharmacotherapy, ISSN: 02770008
Bharati Bhardwaja; Nikki M. Carroll; Marsha A. Raebel; Elizabeth A. Chester; Korner; Bob E. Rocho; David W. Brand; David J. Magid
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International consensus for a definition of disease flare in lupus
Lupus, ISSN: 09612033
Nicolino Ruperto; Hanrahan; Graciela S. Alarcõn; Belmont; Brey; Paul Brunetta; Jill P. Buyon; Costner; Cronin; Dooley; Filocamo; Fiorentino; Fortin; Franks; Gary S. Gilkeson; Ginzler; Gordon; Grossman; Hahn; David A. Isenberg; Kenneth C. Kalunian; Michelle Petri; Sammaritano; Sánchez-Guerrero; Sontheimer; Vibeke Strand; Urowitz; Von Feldt; Werth; Merrill
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Do cilia put brakes on the cell cycle?
Nature Cell Biology, ISSN: 14657392
Peter K Jackson
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Functional characterization of putative cilia genes by high-content analysis
Molecular Biology of the Cell, ISSN: 10591524 19394586
Cary K. Lai; Nidhi Gupta; Xiaohui Wen; Linda Rangell; Ben Chih; Andrew S. Peterson; J.Fernando Bazan; Li Li; Suzie J. Scales
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NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling
Cell, ISSN: 00928674
Sharon Biton; Avi Ashkenazi
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Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocytespecific deletion of JAK2
Journal of Clinical Investigation, ISSN: 15588238 00219738
Brandon C. Sos; Charles Harris; Sarah M. Nordstrom; Jennifer L. Tran; Mercedesz Balazs; Patrick Caplazi; Maria Febbraio; Milana A. B. Applegate; Kay-Uwe Wagner; Ethan J. Weiss
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Integrated cytogenetic and high-resolution array CGH analysis of genomic alterations associated with MYCN amplification
Cytogenetic and Genome Research, ISSN: 14248581
Ajay Pandita; Bayani; Paderova; Marrano; Graham; Barrett; Prasad; Zielenska; Squire
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BioBeat: ICBE explores biology at the molecular level
Chemical Engineering Progress, ISSN: 03607275
Deshayes
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A humanized monoclonal antibody targeting the β7 integrin selectively blocks intestinal homing of T lymphocytes
British Journal of Pharmacology, ISSN: 00071188 14765381
Stefanich; Dimitry Danilenko; Hong Wang; Sharon O'Byrne; Erickson; Thomas R. Gelzleichter; Hajime Hiraragi; Chiu; Ivelja; Surinc Er Jeet; Gadkari; Hwang; Franklin Fuh; Looney; Howell; Albert; Mercedesz Balazs; Refino; Fong; Suhasini Iyer; Marna Williams
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An observational study of outcomes after initial infused therapy in Medicare patients diagnosed with chronic lymphocytic leukemia
Blood, ISSN: 15280020 00064971
Mark Danese; Robert I. Griffiths; Michelle Gleeson; Sacha Satram-Hoang; Kevin Knopf; Joseph Mikhael; Carolina Reyes
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A MEK inhibitor abrogates myeloproliferative disease in Kras mutant mice
Science Translational Medicine, ISSN: 19466234 19466242
Natalya Lyubynska; Matthew F. Gorman; Jennifer O. Lauchle; Wan Xing Hong; Jon Akutagawa; Kevin Shannon; Benjamin S. Braun
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Advancing translational research
Science, ISSN: 10959203 00368075
Brad Bolon; Bruce Altrock; Stephen W. Barthold; Nicole Baumgarth; David Besselsen; Gregory Boivin; Kelli L. Boyd; Cory Brayton; Robert D. Cardiff; Suzana Couto; Kathryn A. Eaton; Oded Foreman; Stephen M. Griffey; la Perle; Michael D. Lairmore; Chen Liu; David K. Meyerholz; Alexander Yu. Nikitin; Trenton R. Schoeb; Denise Schwahn; Rani Sellers; John P. Sundberg; Ravi Tolwani; Victor E. Valli; M. Christine Zink
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Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activity
Journal of Medicinal Chemistry, ISSN: 00222623 15204804
Brad E Sleebs; Czabotar; Wayne J. Fairbrother; Fairlie; Flygare; David C.S. Huang; Wilhelmus J A Kersten; Michael F. T. Koehler; Guillaume Lessene; Kym N Lowes; John P Parisot; Brian J. Smith; Morey L. Smith; Andrew J. Souers; Ian P Street; Hong Yang; Jonathan B Baell
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FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways
PLoS ONE, ISSN: 19326203
Ai-Luen Wu; Sally Coulter; Christopher Liddle; Anne Wong; Jeffrey Eastham-Anderson; French; Andrew S. Peterson; Junichiro Sonoda
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Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cell
Journal of Medicinal Chemistry, ISSN: 00222623 15204804
Stephanie M. Stanford; Divya Krishnamurthy; Matthew D. Falk; Rossella Messina; Bikash Debnath; Sheng Li; Tong Liu; Roza Kazemi; Russell Dahl; Yantao He; Xiao Yu; Andrew A. Chan; Zhong-Yin Zhang; Amy M. Barrios; Virgil L. Woods Jr.; Nouri Neamati; Nunzio Bottini
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Matrix metalloproteinase-9 predicts pulmonary status declines in α1-antitrypsin deficiency
Respiratory Research, ISSN: 1465993X 14659921
Theodore A. Omachi; Mark D. Eisner; Alexis Rames; Lada Markovtsova; Paul D. Blanc
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Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes
PLoS ONE, ISSN: 19326203
Rezaul Karim; Craig Meyers; Claude Backendorf; Kristina Ludigs; Rienk Offringa; Gert-Jan B. van Ommen; Cornelis J. M. Melief; Sjoerd H. van der Burg; Judith M. Boer
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Effects of anti-VEGF on predicted antibody biodistribution: Roles of vascular volume, interstitial volume, and blood flow
PLoS ONE, ISSN: 19326203
C. Andrew Boswell; Gregory Z. Ferl; Eduardo E. Mundo; Daniela Bumbaca; Michelle G. Schweiger; Frank-Peter Theil; Fielder; Leslie A. Khawli
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CD40 pathway activation status predicts response to CD40 therapy in diffuse large B cell lymphoma
Science Translational Medicine, ISSN: 19466234 19466242
Bart Burington; Peng Yue; Xiaoyan Shi; Ranjana H. Advani; Jeffrey Lau; Jenille Tan; Susanna Y. Stinson; Stinson; Thomas Januario; Sven De Vos; Stephen Ansell; Andres Forero; Grazyna Fedorowicz; Teddy T. C. Yang; Kristi Elkins; Du; Sankar Mohan; Nancy Yu; Zora Modrusan; Somasekar Seshagiri; Shang-Fan Yu; Ajay Pandita; Koeppen; French; Andrew G. Polson; Rienk Offringa; Nancy Whiting; Allen Ebens; David Dornan
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Remote functionalisation via sodium alkylamidozincate intermediates: Access to unusual fluorenone and pyridyl ketone reactivity patterns
Chemical Communications, ISSN: 1364548X 13597345
James J. Crawford; Ben J. Fleming; Kennedy; Charles T. O’Hara; Samantha A. Orr
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Navitoclax enhances the efficacy of taxanes in non-small cell lung cancer models
Clinical Cancer Research, ISSN: 10780432 15573265
Nguyen Tan; Mehnaz Malek; Jiping Zha; Peng Yue; Robert Kassees; Berry; Wayne J. Fairbrother; Deepak Sampath; Lisa D. Belmont
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Identification of isomerization and racemization of aspartate in the Asp-Asp motifs of a therapeutic protein
Analytical Biochemistry, ISSN: 10960309 00032697
Jennifer Zhang; Holly Yip; Viswanatham Katta
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Effect of CC chemokine receptor 2 CCR2 blockade on serum C-reactive protein in individuals at atherosclerotic risk and with a single nucleotide polymorphism of the monocyte chemoattractant protein-1 promoter region
American Journal of Cardiology, ISSN: 00029149
Jim Gilbert; Julie Lekstrom-Himes; Debra Donaldson; Yih Lee; Mingxiu Hu; Jing Xu; Tim Wyant; Michael Davidson
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Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells
Cancer Research, ISSN: 00085472 15387445
Yong-Yu Liu; Gauri A. Patwardhan; Kaustubh Bhinge; Vineet Gupta; Xin Gu; S. Michal Jazwinski
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Remote functionalisation via sodium alkylamidozincate intermediates: Access to unusual fluorenone and pyridyl ketone reactivity patterns
Chemical Communications, ISSN: 1364548X 13597345
James J. Crawford; Ben J. Fleming; Alan R. Kennedy; Charles T. O’Hara; Samantha A. Orr
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Mitochondrial reactive oxygen species drive proinflammatory cytokine production
Journal of Experimental Medicine, ISSN: 00221007 15409538
Naik; Vishva M. Dixit
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Impact of β2 integrin deficiency on mouse natural killer cell development and function
Blood, ISSN: 15280020 00064971
Karine Crozat; Celine Eidenschenk; Baptiste N. Jaeger; Philippe Krebs; Sophie Guia; Bruce Beutler; Eric Vivier; Sophie Ugolini
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Development of a multi-product leached protein A assay for bioprocess samples containing recombinant human monoclonal antibodies
Journal of Immunological Methods, ISSN: 00221759
Diya Ren; Maria R. Darlucio; Judy H. Chou
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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7
Nature, ISSN: 00280836 14764687
Ingrid E. Wertz; Saritha Kusam; Cynthia Lam; Toru Okamoto; Wendy N. Sandoval; Daniel J Anderson; Elizabeth Helgason; James A. Ernst; Mike Eby; Jinfeng Liu; Lisa D. Belmont; Joshua S. Kaminker; Karen M. O'Rourke; Kanan Pujara; Pawan Bir Kohli; Adam R. Johnson; Mark L. Chiu; Jennie R. Lill; Peter K Jackson; Wayne J. Fairbrother; Somasekar Seshagiri; Mary J. C. Ludlam; Kevin G. Leong; Erin C. Dueber; Heather Maecker; David C.S. Huang; Vishva M. Dixit
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Dense mapping of IL18 shows no association in SLE
Human Molecular Genetics, ISSN: 09646906 14602083
Sandra G. Guerra; David L. Morris; Vesela Gateva; Robert R. Graham; Timothy J. Vyse; Deborah S. Cunninghame Graham
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Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production
PLoS Genetics, ISSN: 15537390 15537404
Sharon A. Chung; Kimberly E. Taylor; Robert R. Graham; Joanne Nititham; Annette T. Lee; Ward Ortmann; Chaim O. Jacob; Marta E. Alarcón-Riquelme; Betty P. Tsao; John B. Harley; Patrick M. Gaffney; Kathy L. Moser; Michelle Petri; F. Yesim Demirci; M. Ilyas Kamboh; Manzi; Peter K. Gregersen; Carl D. Langefeld; Timothy W. Behrens; Criswell
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DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression
Neuro-Oncology, ISSN: 15228517 15235866
Shichun Zheng; E. Andres Houseman; Zachary Morrison; Margaret R. Wrensch; Joseph S. Patoka; Christian Ramos; Daphne A. Haas-Kogan; Sean McBride; Carmen J. Marsit; Brock C. Christensen; Heather H. Nelson; David Stokoe; Joseph L. Wiemels; Susan Chang; Michael D. Prados; Tarik Tihan; Scott R. VandenBerg; Karl T. Kelsey; Mitchel S. Berger; John K. Wiencke
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The minimum L2 distance estimator for Poisson mixture models
Journal of Statistical Planning and Inference, ISSN: 03783758
Ian R. Harris; Shuyi Shen
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Challenges in developing bioanalytical assays for characterization of antibody-drug conjugates
Bioanalysis, ISSN: 17576180 17576199
Jean-Philippe Stephan; Katherine R. Kozak; Wai Lee T. Wong
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American college of rheumatology/European league against rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials
Arthritis and Rheumatism, ISSN: 00043591 15290131
David T. Felson; Josef S. Smolen; George Wells; Bin Zhang; Lilian H.D. Van Tuyl; Julia Funovits; Daniel Aletaha; Allaart; Joan Bathon; Stefano Bombardieri; Peter Brooks; Andrew Brown; Marco Matucci-Cerinic; Hyon Choi; Bernard Combe; Maarten De Wit; Maxime Dougados; Paul Emery; Daniel E. Furst; Juan Gomez-Reino; Gillian Hawker; Edward Keystone; Dinesh Khanna; John Kirwan; Tore K. Kvien; Robert Landewé; Joachim Listing; Kaleb Michaud; Emilio Martin-Mola; Pamela Montie; Theodore Pincus; Pamela Richards; Jeffrey N. Siegel; Lee S. Simon; Tuulikki Sokka; Vibeke Strand; Peter Tugwell; Alan Tyndall; Desirée Van Der Heijde; Suzan Verstappen; Barbara White; Frederick Wolfe; Angela Zink; Maarten Boers
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Characteristics of patients losing vision after 2 years of monthly dosing in the phase III ranibizumab clinical trials
Ophthalmology, ISSN: 01616420
Philip J. Rosenfeld; Howard Shapiro; Lisa Tuomi; Mary Webster; Julee Elledge; Barbara A. Blodi
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An antibody-drug conjugate targeting the endothelin B receptor for the treatment of melanoma
Clinical Cancer Research, ISSN: 10780432 15573265
Jyoti Asundi; Chae Reed; Jennifer Arca; Krista McCutcheon; Ron Ferrando; Suzanna Clark; Luis; Janet Y. Tien; Ron Firestein; Paul G. Polakis
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Myocardial infarction and cerebrovascular accident in patients with retinal vein occlusion
Archives of Ophthalmology, ISSN: 00039950 15383601
Winifred Werther; Laura Chu; Nancy Holekamp; Diana V. Do; Roman G. Rubio
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Prioritizing "psychological" consequences for disaster preparedness and response: A framework for addressing the emotional, behavioral, and cognitive effects of patient surge in large-scale disasters
Disaster Medicine and Public Health Preparedness, ISSN: 19357893 1938744X
Lisa S. Meredith; David P. Eisenman; Terri Tanielian; Stephanie L. Taylor; Ricardo Basurto-Davila; James L. Zazzali; Dickson Diamond; Barbara Cienfuegos; Sandra Shields
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Bioanalytical approaches to quantify "total" and "free" therapeutic antibodies and their targets: Technical challenges and PK/PD applications over the course of drug development
AAPS Journal, ISSN: 15507416
Jean W. Lee; Marian Kelley; Lindsay King; Yang; Hossein Salimi-Moosavi; Meina Tao Tang; Jian-Feng Lu; John Kamerud; Ago Ahene; Heather Myler; Cindy Rogers
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Single-use technology roundtable
American Pharmaceutical Review, ISSN: 10998012
Lindsay Leveen; Jonathan Royce; Maik W. Jornitz; Michael LaBreck; Juliette Schick; Rick Stock; Nick Warne; Helene Pora; Peter Lambert
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