Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9401 - 9450 OF 15805 RESULTS

Signaling to NF-kappaB: regulation by ubiquitination.
Cold Spring Harbor Perspectives in Biology, ISSN: 19430264
Ingrid E. Wertz; Vishva M. Dixit
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Interplay of dissolution, solubility, and nonsink permeation determines the oral absorption of the hedgehog pathway inhibitor GDC-0449 in dogs: An investigation using preclinical studies and physiologically based pharmacokinetic modeling
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Harvey Wong; Frank-Peter Theil; Yong Cui; James C. Marsters Jr.; S. Cyrus Khojasteh; Laurent Vernillet; Hank La; Xiling Song; Hong Wang; Eric Morinello; Yuzhong Deng; Cornelis E. Hop
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On the influence of protein binding on pharmacological activity of drugs
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Vision-Related Function after Ranibizumab Treatment by Better- or Worse-Seeing Eye. Clinical Trial Results from MARINA and ANCHOR
Ophthalmology, ISSN: 01616420
Neil M. Bressler; Tom S. Chang; Ivan J. Suñer; Jennifer T. Fine; Chantal M. Dolan; James Ward; Tsontcho Ianchulev
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PlGF Blockade Does Not Inhibit Angiogenesis during Primary Tumor Growth
Cell, ISSN: 00928674
Carlos Bais; Xiumin Wu; Jenny Yao; Suya Yang; Yongping Crawford; Krista McCutcheon; Christine Tan; Ganesh Kolumam; Jean-Michel Vernes; Jeffrey Eastham-Anderson; Peter Haughney; Marcin Kowanetz; Thijs Hagenbeek; Ian Kasman; Hani Bou-Reslan; Ross; Nicholas Van Bruggen; Richard A. D. Carano; Yu-Ju Gloria Meng; Hongo; Jean-Philippe Stephan; Masabumi Shibuya; Napoleone Ferrara
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Elusive identities and overlapping phenotypes of proangiogenic myeloid cells in tumors
American Journal of Pathology, ISSN: 15252191 00029440
Seth B. Coffelt; Claire E. Lewis; Luigi Naldini; J. Martin Brown; Napoleone Ferrara; Michele De Palma
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Vibrational spectroscopy and chemometrics to characterize and quantitate trehalose crystallization
Analytical Biochemistry, ISSN: 10960309 00032697
Brian D. Connolly; Thomas W. Patapoff; Y. John Wang; Jamie M. R. Moore; Tim J. Kamerzell
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Ricinus communis agglutinin I leads to rapid down-regulation of VEGFR-2 and endothelial cell apoptosis in tumor blood vessels
American Journal of Pathology, ISSN: 15252191 00029440
Weon-Kyoo You; Ian Kasman; Dana D. Hu-Lowe; Donald M. McDonald
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Functions of type II pneumocyte-derived vascular endothelial growth factor in alveolar structure, acute inflammation, and vascular permeability
American Journal of Pathology, ISSN: 15252191 00029440
Marco Mura; Matthew Binnie; Bing Han; Chengjin Li; Cristiano F. Andrade; Atsushi Shiozaki; Yu Zhang; Napoleone Ferrara; David Hwang; Thomas K. Waddell; Shaf Keshavjee; Mingyao Liu
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Co-expression of ferrochelatase allows for complete heme incorporation into recombinant proteins produced in E. coli
Protein Expression and Purification, ISSN: 10465928
Jawahar Sudhamsu; Mariam Kabir; Michael V. Airola; Bhumit A. Patel; Syun-Ru Yeh; Denis L. Rousseau; Brian R. Crane
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On developing a process for conducting extractable-leachable assessment of components used for storage of biopharmaceuticals
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Aditya A. Wakankar; Y. John Wang; Eleanor Canova-Davis; Stacey Ma; Dieter Schmalzing; Josh Grieco; Terry Milby; Theresa Reynolds; Mazzarella; Ed Hoff; Stephen Gomez; Sheryl Martin-Moe
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Two lab tests help clinicians diagnose and predict ischemic stroke.
Managed Care, ISSN: 10623388
Thomas Morrow
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Asthma and the prospective risk of anaphylactic shock and other allergy diagnoses in a large integrated health care delivery system
Annals of Allergy, Asthma and Immunology, ISSN: 15344436 10811206
Carlos Iribarren; Irina V. Tolstykh; Mary K. Miller; Mark D. Eisner
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An automated method for nonparametric kinetic analysis of clinical DCE-MRI data: Application to glioblastoma treated with bevacizumab
Magnetic Resonance in Medicine, ISSN: 15222594 07403194
Gregory Z. Ferl; Lu Xu; Michel Friesenhahn; Lisa J. Bernstein; Daniel P. Barboriak; Ruediger E. Port
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Manipulation of host cell death pathways during microbial infections
Cell Host and Microbe, ISSN: 19346069 19313128
Lamkanfi; Vishva M. Dixit
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Vessel imaging with viable tumor analysis for quantification of tumor angiogenesis
Magnetic Resonance in Medicine, ISSN: 15222594 07403194
Sharon E. Ungersma; Glenn Pacheco; Calvin Ho; Sharon Fong Yee; Ross; Nicholas Van Bruggen; Franklin V. Peale Jr.; Ross; Richard A. D. Carano
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Ranibizumab for Macular Edema following Branch Retinal Vein Occlusion. Six-Month Primary End Point Results of a Phase III Study
Ophthalmology, ISSN: 01616420
Peter A. Campochiaro; Jeffrey S. Heier; Leonard Feiner; Sarah Gray; Namrata Saroj; Amy Chen Rundle; Wendy Yee Murahashi; Roman G. Rubio
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Early menstrual characteristics associated with subsequent diagnosis of endometriosis
American Journal of Obstetrics and Gynecology, ISSN: 00029378
Susan A. Treloar; Tanya A. Bell; Christina M. Nagle; David M. Purdie; Adèle C. Green
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Ranibizumab for Macular Edema following Central Retinal Vein Occlusion. Six-Month Primary End Point Results of a Phase III Study
Ophthalmology, ISSN: 01616420
David M. Brown; Peter A. Campochiaro; Rishi Singh; Zhengrong Li; Sarah Gray; Namrata Saroj; Amy Chen Rundle; Roman G. Rubio; Wendy Yee Murahashi
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Incidence of New Choroidal Neovascularization in Fellow Eyes of Patients Treated in the MARINA and ANCHOR Trials
American Journal of Ophthalmology, ISSN: 00029394
Irene Barbazetto; Namrata Saroj; Howard Shapiro; Pamela Wong; Allen C. Ho; K. Bailey Freund
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O-fucose modulates notch-controlled blood lineage commitment
American Journal of Pathology, ISSN: 15252191 00029440
Quanjian Yan; David Yao; Lebing L. Wei; Yuanshuai Huang; Jay Myers; Lihua Zhang; Wei Xin; Jeongsup Shim; Yunfang Man; Bronislawa Petryniak; Stanton Gerson; John Lowe; Lan Zhou
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The chemical toolbox for monitoring protein fatty acylation and prenylation
Nature Chemical Biology, ISSN: 15524469 15524450
Rami N. Hannoush; Jinglucy Sun
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Molecular dynamics simulations of hydrotropic solubilization and self-aggregation of nicotinamide
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Yong Cui; Chenyue Xing; Yingqing Ran
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Vascular endothelial growth factor and age-related macular degeneration: From basic science to therapy
Nature Medicine, ISSN: 1546170X 10788956
Napoleone Ferrara
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Noncompartmental kinetic analysis of DCE-MRI data from malignant tumors: Application to glioblastoma treated with bevacizumab
Magnetic Resonance in Medicine, ISSN: 15222594 07403194
Ruediger E. Port; Lisa J. Bernstein; Daniel P. Barboriak; Lu Xu; Timothy P.L. Roberts; Nicholas Van Bruggen
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RTM3, which controls long-distance movement of potyviruses, is a member of a new plant gene family encoding a meprin and TRAF homology domain-containing protein
Plant Physiology, ISSN: 15322548 00320889
Patrick Cosson; Luc Sofer; Quang Hien Le; Valérie Léger; Valérie Schurdi-Levraud; Steven A. Whitham; Miki L. Yamamoto; Suresh Gopalan; Olivier le Gall; Thierry Candresse; James C. Carrington; Frédéric Revers
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Characterization of a nutrient feed precipitate from an E. coli fermentation process.
Biotechnology Progress, ISSN: 15206033
Lauren Speciner; Erin Mallon; Susan Leung; Mike Laird; Osigwe Esue
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Anti-CD22-MCC-DM1: An antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma
Leukemia, ISSN: 14765551 08876924
Andrew G. Polson; Marna Williams; Gray; Reina N. Fuji; Kirsten Achilles Poon; Jacqueline McBride; Helga Raab; Thomas Januario; MaryAnn Go; Jeffrey Lau; Shang-Fan Yu; Du; Franklin Fuh; Christine Tan; Yan Wu; Wei-Ching Liang; Saileta Prabhu; Jean-Philippe Stephan; Hongo; Randall Dere; Rong Deng; Cullen; Ruth De Tute; Bennett; Andy Rawstron; Andrew S. Jack; Allen Ebens
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Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency
Nature Genetics, ISSN: 15461718 10614036
Ricardo C. Ferreira; Qiang Pan-Hammarström; Robert R. Graham; Vesela Gateva; Gumersindo Fontán; Annette T. Lee; Ward Ortmann; Elena Urcelay; Miguel Fernández-Arquero; Concepción Núñez; Gudmundur Jorgensen; Björn R. Ludviksson; Sinikka Koskinen; Katri Haimila; Hilary F. Clark; Lars Klareskog; Peter K. Gregersen; Timothy W. Behrens; Lennart Hammarström
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Treatment outcomes by tumor histology in eastern cooperative group study E4599 of bevacizumab with paclitaxel/carboplatin for advanced non-small cell lung cancer
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Alan Sandler; Jing Yi; Suzanne Dahlberg; Margaret M. Kolb; Lisa I. Wang; Julie Hambleton; Joan H. Schiller; David H. Johnson
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Monoclonal antibody purification using cationic polyelectrolytes: an alternative to column chromatography.
Biotechnology Progress, ISSN: 15206033
Thanmaya Peram; Paul McDonald; Jayme N. Carter-Franklin; Fahrner
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Effect of temperature, pH, dissolved oxygen, and hydrolysate on the formation of triple light chain antibodies in cell culture.
Biotechnology Progress, ISSN: 15206033
Natalia Gomez; Jun Ouyang; Mary D. H. Nguyen; Abigail R Vinson; Andy Lin; Inn H. Yuk
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Structure of the Complex between HER2 and an Antibody Paratope Formed by Side Chains from Tryptophan and Serine
Journal of Molecular Biology, ISSN: 00222836
Robert D. Fisher; Ultsch; Andreas Lingel; Gabriele Schaefer; Lily Shao; Sara Birtalan; Sachdev S. Sidhu; Eigenbrot
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Randomized, double-masked, sham-controlled trial of ranibizumab for neovascular age-related macular degeneration: PIER study year 2
American Journal of Ophthalmology, ISSN: 00029394
Prema Abraham; Huibin Yue; Laura J. Wilson
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On the possibility of self-induction of drug protein binding
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Questions about coverage accompany new fully implantable hearing system
Managed Care, ISSN: 10623388
Thomas Morrow
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Molecular biomarker analyses using circulating tumor cells
PLoS ONE, ISSN: 19326203
Elizabeth A. Punnoose; Siminder Atwal; Jill M. Spoerke; Heidi Savage; Ajay Pandita; Ru-Fang Yeh; Andrea Pirzkall; Bernard M. Fine; Lukas Amler; Daniel S. Chen; Lackner
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Cell biology redux.
Molecular Biology of the Cell, ISSN: 19394586
Ira Mellman
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Molecular mechanisms of regulatory T cell development and suppressive function
Progress in Molecular Biology and Translational Science, ISSN: 18771173
Kim
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Surface expression of precursor N-cadherin promotes tumor cell invasion
Neoplasia (United States), ISSN: 14765586 15228002
Deborah Maret; Eugenia Gruzglin; Mohamad Seyed Sadr; Vincent Siu; Shan; Alexander W. Koch; Nabil G. Seidah; Rolando F. del Maestro; David R. Colman
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Standardizing rodent trimming and embedding guidelines for histology: Improving efficiency in the laboratory
Journal of Histotechnology, ISSN: 01478885
Monika Larson; Taylor; Marjie Van Hoy
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Factors affecting the viscosity in high concentration solutions of different monoclonal antibodies
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Sandeep Yadav; Steven J. Shire; Devendra S. Kalonia
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Semi-automated protein binding methodology using equilibrium dialysis and a novel mixed-matrix cassette approach
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Emile G. Plise; Daniel Tran; Laurent Salphati
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Pharmaceutical medical information contact centers: Results of three benchmarking surveys
Drug Information Journal, ISSN: 00928615
Pete Guillot; Stacey M. Fung
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Foreword
Separation Science and Technology, ISSN: 15205754 01496395
James M. van Alstine; Philip M. Lester
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Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture
PLoS Computational Biology, ISSN: 15537358 1553734X
Ju Han; Hang Chang; Orsi Giricz; Genee Y. Lee; Frederick L. Baehner; Joe W. Gray; Mina J. Bissell; Paraic A. Kenny; Bahram Parvin
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Robust preparation of novel imidazo[5,1-b][1,3,4]oxadiazoles
Organic and Biomolecular Chemistry, ISSN: 14770520
Tuan P. Tran; Nandini C. Patel; Brian Samas; Jacob B. Schwarz
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Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17
Journal of Experimental Medicine, ISSN: 00221007 15409538
Melba Muñoz; Markus Heimesaat; Kerstin Danker; Daniela Struck; Uwe Lohmann; Rita Plickert; Stefan Bereswill; André Fischer; Ildikò Rita Dunay; Kerstin Wolk; Christoph Loddenkemper; Hans-Willi Krell; Claude Libert; Leif R. Lund; Oliver Frey; Christoph Hölscher; Yoichiro Iwakura; Nico Ghilardi; Wenjun Ouyang; Thomas Kamradt; Robert Sabat; Oliver Liesenfeld
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Interlaced size exclusion liquid chromatography of monoclonal antibodies
Journal of Chromatography A, ISSN: 00219673
Dell Farnan; G. Tony Moreno; Stults; Andreas Becker; Guillaume Tremintin; Mark van Gils
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Improving therapeutic efficacy of a complement receptor by structure-based affinity maturation
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Bing Li; Hongkang Xi; Laurie Diehl; Wyne P. Lee; Lizette Sturgeon; Jason Chinn; Laura DeForge; Robert F. Kelley; Wiesmann; Menno Van Lookeren Campagne; Sachdev S. Sidhu
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