Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9651 - 9700 OF 15657 RESULTS

January 1, 2009

Targeting the purinome.

Methods in Molecular Biology, ISSN: 19406029

Jeremy Murray; Dirksen Bussiere

January 1, 2009

Therapeutic potential of an anti-CD79b antibody-drug conjugate, anti-CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma

Blood, ISSN: 15280020 00064971

David Dornan; Bennett; Chen; Dennis; Dan L. Eaton; Kristi Elkins; French; MaryAnn Go; Andrew S. Jack; Jagath R. Junutula; Koeppen; Jeffrey Lau; Jacqueline McBride; Andy Rawstron; Xiaoyan Shi; Nancy Yu; Shang-Fan Yu; Peng Yue; Bing Zheng; Allen Ebens; Andrew G. Polson

January 1, 2009

Prediction of the possibility of the secondary peaks of iv bolus drug plasma concentration time curve by the model that directly takes into account the transit time through the organ

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Leonid M. Berezhkovskiy

January 1, 2009

Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe asthma exacerbations in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study

Journal of Allergy and Clinical Immunology, ISSN: 00916749

Tmirah Haselkorn; James E. Fish; Robert S. Zeiger; Stanley J. Szefler; Dave P. Miller; Bradley E. Chipps; F. Estelle R. Simons; Weiss; Sally E. Wenzel; Larry Borish; Eugene R. Bleecker

January 1, 2009

Design and construction of synthetic phage-displayed Fab libraries.

Methods in Molecular Biology, ISSN: 10643745

Jenny Bostrom; Fuh

January 1, 2009

Orphan disease gains second treatment option

Managed Care, ISSN: 10623388

Thomas Morrow

January 1, 2009

Expanded availability of isotope boon to neuroblastoma diagnosis

Managed Care, ISSN: 10623388

Thomas Morrow

January 1, 2009

Transgenic goats are key to antithrombin production

Managed Care, ISSN: 10623388

Thomas Morrow

January 1, 2009

Sensitivity of administrative claims to identify incident cases of lung cancer: A comparison of 3 health plans

Journal of Managed Care Pharmacy, ISSN: 10834087

Scott D. Ramsey; John F. Scoggins; David Blough; Cara L. McDermott; Carolina Reyes

January 1, 2009

A stepwise increase in recombinant human growth hormone dosing during puberty achieves improved pubertal growth: A national cooperative growth study report

Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X

Linda Riddick; Craig Alter; Daniel Aaron Davis; James W. Frane; Barbara M. Lippe; Bert Bakker

January 1, 2009

Viscoelastic characterization of high concentration antibody formulations using quartz crystal microbalance with dissipation monitoring

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Ankit Patel; Bruce A. Kerwin; Sekhar R. Kanapuram

January 1, 2009

Baseline characteristics of patients enrolled in EXCELS: A cohort study

Annals of Allergy, Asthma and Immunology, ISSN: 15344436 10811206

Aidan Long; James E. Fish; Abdelkader Rahmaoui; Mary K. Miller; Mary S. Bradley; Hassan N. Taki; Anthony N. Demeo; Stephen A. Tilles; Stanley J. Szefler

January 1, 2009

Root UV-B sensitive2 acts with root UV-B sensitive1 in a root ultraviolet B-sensing pathway

Plant Physiology, ISSN: 15322548 00320889

Colin D. Leasure; Hongyun Tong; Gigi Yuen; Xuewen Hou; Xuefeng Sun; Zheng-Hui He

January 1, 2009

Prasugrel, new platelet inhibitor, subject of formulary debates.

Managed Care, ISSN: 10623388

Thomas Morrow

January 1, 2009

Assessing medical information needs via an internet-based survey

Drug Information Journal, ISSN: 00928615

Stacey M. Fung; Laura Merriman; Maureen Cawley

January 1, 2009

Identification of circulating neuropilin-1 and dose-dependent elevation following anti-neuropilin-1 antibody administration

mAbs, ISSN: 19420862

Yanmei Lu; Hong Xiang; Peter S. Liu; Raymond K. Tong; Ryan J. Watts; Alexander W. Koch; Wendy N. Sandoval; Lisa A. Damico; Lee Wong Wai; Meng

January 1, 2009

The fate of free radicals in a cellulose based hydrogel: Detection by electron paramagnetic resonance spectroscopy

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Lipika Basumallick; Junyan A. Ji; Nariman Naber; Y. John Wang

January 1, 2009

A tumor sorting protocol that enables enrichment of pancreatic adenocarcinoma cells and facilitation of genetic analyses

Journal of Molecular Diagnostics, ISSN: 15251578

Zachary Boyd; Rajiv Raja; Stephanie Johnson; Eberhard; Lackner

January 1, 2009

Growth response, near-adult height, and patterns of growth and puberty in patients with Noonan syndrome treated with growth hormone

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X

Alicia A. Romano; Ken Dana; Bert Bakker; Daniel Aaron Davis; Joanne Julius Hunold; Joan R. Jacobs; Barbara M. Lippe

January 1, 2009

Using empirical phase diagrams to understand the role of intramolecular dynamics in immunoglobulin G stability

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Joshua D. Ramsey; Michelle L. Gill; Tim J. Kamerzell; E. Shane Price; Sangeeta B. Joshi; Steven M. Bishop; Cynthia N. Oliver; C. Russell Middaugh

January 1, 2009

Absence of neuromyelitis optica igg antibody in an active relapsing-remitting multiple sclerosis population

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, ISSN: 15365166 10708022

Craig H. Smith; Waubant; Annette Langer-Gould

January 1, 2009

On the prediction of hepatic clearance using the diluted plasma in metabolic stability assay

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Leonid M. Berezhkovskiy; S. Cyrus Khojasteh; Jason S Halladay; Cornelis E. Hop

January 1, 2009

Relative weight at ages 10 and 16 years and risk of endometriosis: A case-control analysis

Human Reproduction, ISSN: 14602350 02681161

Christina M. Nagle; Tanya A. Bell; David M. Purdie; Susan A. Treloar; Olsen; Grover; Adèle C. Green

January 1, 2009

Predicting asthma control using patient attitudes toward medical care: The REACT score

Annals of Allergy, Asthma and Immunology, ISSN: 15344436 10811206

Craig A. Jones; Bruce G. Bender; Tmirah Haselkorn; James E. Fish; David R. Mink; Stephen P. Peters; Weiss

January 1, 2009

Improving antibody binding affinity and specificity for therapeutic development.

Methods in Molecular Biology, ISSN: 10643745

Jenny Bostrom; Chingwei V. Lee; Lauric Haber; Fuh

January 1, 2009

Determination of mean residence time of drug in plasma and the influence of the initial drug elimination and distribution on the calculation of pharmacokinetic parameters

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Leonid M. Berezhkovskiy

January 1, 2009

Compatibility of a protein topical gel with wound dressings

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Junyan A. Ji; Oleg V. Borisov; Erika Ingham; Victor Ling; Y. John Wang

January 1, 2009

Applying the CONSORT and STROBE Statements to Evaluate the Reporting Quality of Neovascular Age-related Macular Degeneration Studies

Ophthalmology, ISSN: 01616420

Anne E. Fung; Ram Palanki; Sophie J. Bakri; Eric E. Depperschmidt; Andrea Gibson

January 1, 2009

Consideration of the linear concentration increase of the unbound drug fraction in plasma

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Leonid M. Berezhkovskiy

January 1, 2009

Anion exchange chromatography provides a robust, predictable process to ensure viral safety of biotechnology products

Biotechnology and Bioengineering, ISSN: 00063592 10970290

Daniel M. Strauss; Gorrell; Magdalena Plancarte; Gregory S. Blank; Qi Chen; Bin Yang

January 1, 2009

Slow growth induces heat-shock resistance in normal and respiratory-deficient yeast

Molecular Biology of the Cell, ISSN: 10591524

Charles Lu; Matthew J. Brauer; David Botstein

January 1, 2009

Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP21

Biochemical Journal, ISSN: 02646021 14708728

John W. Blankenship; Eugene Varfolomeev; Tatiana Goncharov; Anna V. Fedorova; Donald S. Kirkpatrick; Anita Izrael-Tomasevic; Lilian Phu; David Arnott; Mariam Aghajan; Zobel; J.Fernando Bazan; Wayne J. Fairbrother; Deshayes; Domagoj Vucic

January 1, 2009

Coordinated concentration changes of transcripts and metabolites in Saccharomyces cerevisiae

PLoS Computational Biology, ISSN: 1553734X 15537358

Patrick H. Bradley; Matthew J. Brauer; Joshua D. Rabinowitz; Olga G. Troyanskaya

January 1, 2009

Sparse combinatorial inference with an application in cancer biology

Bioinformatics, ISSN: 13674803 14602059

Sach Mukherjee; Steven Pelech; Richard M. Neve; Wen-Lin Kuo; Safiyyah Ziyad; Paul T. Spellman; Joe W. Gray; Terence P. Speed

January 1, 2009

Twenty-four well plate miniature bioreactor system as a scale-down model for cell culture process development

Biotechnology and Bioengineering, ISSN: 00063592 10970290

Aaron Chen; Rajesh Chitta; David Chang; Ashraf Amanullah

January 1, 2009

Erythropoietin dosing in children with chronic kidney disease: Based on body size or on hemoglobin deficit?

Pediatric Nephrology, ISSN: 0931041X

Ruediger E. Port; Otto Mehls

January 1, 2009

Computational prediction of the functional effects of amino acid substitutions in signal peptides using a model-based approach

Human Mutation, ISSN: 10597794

Lawrence S. Hon; Yan Zhang; Joshua S. Kaminker; Zemin Zhang

January 1, 2009

Lipoxin A4 and serum amyloid a differentially modulate phospholipase D in human fibroblast-like synoviocytes

European Journal of Inflammation, ISSN: 1721727X

Sodin-Semrl; Antico; Mikus; Lakota; Varga; Fiore

January 1, 2009

VEGF inhibition: Insights from preclinical and clinical studies

Cell and Tissue Research, ISSN: 0302766X

Yongping Crawford; Napoleone Ferrara

January 1, 2009

Improved vision-related function after ranibizumab vs photodynamic therapy: A randomized clinical trial

Archives of Ophthalmology, ISSN: 00039950 15383601

Neil M. Bressler; Tom S. Chang; Jennifer T. Fine; Chantal M. Dolan; James Ward

January 1, 2009

Polar localization of virulence-related Esx-1 secretion in mycobacteria

PLoS Pathogens, ISSN: 15537366 15537374

Fredric Carlsson; Shilpa A. Joshi; Linda Rangell; Eric J. Brown

January 1, 2009

Mechanism, function and regulation of microtubule-dependent microtubule amplification in mitosis

Molecules and Cells, ISSN: 10168478

Hui Zhu; Kayleen Fang; Guowei Fang

January 1, 2009

Ion-specific modulation of protein interactions: Anion-induced, reversible oligomerization of a fusion protein

Protein Science, ISSN: 09618368 1469896X

Yatin Gokarn; R. Matthew Fesinmeyer; Atul Saluja; Shawn Cao; Jane Dankberg; Andrew Goetze; Richard L. Remmele Jr.; Linda O. Narhi; David N. Brems

January 1, 2009

Quality by design: The next phase

BioProcess International, ISSN: 15426319

Mire-Sluis; Mark Schenerman; Rohin Mhatre; Siddharth Advant; John Dougherty; Steven Kozlowski; Wassim Nashabeh; Lorna McLeod

January 1, 2009

Fucosyltransferase IV and VII-directed selectin ligand function determines long-term survival in experimental tuberculosis

Immunobiology, ISSN: 01712985

Stefan Ehlers; Tanja Schreiber; Annette Dunzendorfer; John Lowe; Christoph Hölscher

January 1, 2009

Panitumumab monotherapy in patients with metastatic colorectal cancer and cetuximab infusion reactions: A series of four case reports

Clinical Colorectal Cancer, ISSN: 15330028

Alan Langerak; George River; Edith Mitchell; Puneet Cheema; Mona Shing

January 1, 2009

Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells

Nature Immunology, ISSN: 15292908 15292916

Tom Cupedo; Natasha K Crellin; Natalie Papazian; Elwin J. Rombouts; Kees Weijer; Jane L. Grogan; Willem E. Fibbe; Jan J. Cornelissen; Hergen Spits

January 1, 2009

Applying simulation tools to evaluate and minimize operating costs of biotech manufacturing facilities

American Pharmaceutical Outsourcing, ISSN: 15296318

Frank Menkel; Rick Johnston; Arden Yang

January 1, 2009

In vivo activity of novel capecitabine regimens alone and with bevacizumab and oxaliplatin in colorectal cancer xenograft models

Molecular Cancer Therapeutics, ISSN: 15357163

Kenneth Kolinsky; Shen; Yu-E. Zhang; Joseph Kohles; Ute Dugan; Zioncheck; David Heimbrook; Kathryn Packman; Higgins

January 1, 2009

Industrialization of mAb production technology: The bioprocessing industry at a crossroads

mAbs, ISSN: 19420862

Kelley

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