Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10101 - 10150 OF 15657 RESULTS

A low cost bumping method for flip chip assembly and MEMS integration
IEEE Transactions on Components and Packaging Technologies, ISSN: 15213331
Jianhua Zhang; Changhai Wang; Jun Zeng; Ah Ju Pang
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Netrins and their receptors
Advances in Experimental Medicine and Biology, ISSN: 00652598
Simon W. Moore; Marc Tessier-Lavigne; Timothy E. Kennedy
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A phylogenetic and functional overview of inflammatory caspases and caspase-1-related CARD-only proteins
Biochemical Society Transactions, ISSN: 03005127
Kersse; Vanden Berghe; Lamkanfi; Vandenabeele
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Safety and efficacy of additional courses of rituximab in patients with active rheumatoid arthritis: An open-label extension analysis
Arthritis and Rheumatism, ISSN: 00043591
Edward Keystone; Roy Fleischmann; Paul Emery; Daniel E. Furst; Ronald Van Vollenhoven; Joan Bathon; Maxime Dougados; Andrew Baldassare; Gianfranco Ferraccioli; Andrew Chubick; James Udell; Matthew W. Cravets; Sunil Agarwal; Simon Cooper; Fabio Magrini
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Efalizumab for the treatment of psoriatic arthritis
Journal of Cutaneous Medicine and Surgery, ISSN: 12034754
Kim Papp; Ivor Caro; Hoi M. Leung; Marvin Garovoy; Philip J. Mease
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Advances in Experimental Medicine and Biology: Foreword
Advances in Experimental Medicine and Biology, ISSN: 00652598
Vishva M. Dixit
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The mitotic regulator survivin binds as a monomer to its functional interactor borealin
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Eric Bourhis; Sarah G. Hymowitz; Andrea G Cochran
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Protein requirements for sister telomere association in human cells
EMBO Journal, ISSN: 02614189 14602075
Silvia Canudas; Benjamin R. Houghtaling; Ju Youn Kim; Jasmin N. Dynek; William G. Chang; Susan Smith
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Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
EMBO Journal, ISSN: 02614189 14602075
Brent A. Appleton; Ping Wu; Janice Maloney; Jianping Yin; Wei-Ching Liang; Scott Stawicki; Kyle Mortara; Krista K. Bowman; J. Michael Elliott; William Desmarais; J.Fernando Bazan; Anil Bagri; Marc Tessier-Lavigne; Alexander W. Koch; Yan Wu; Ryan J. Watts; Wiesmann
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AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements
Journal of Experimental Medicine, ISSN: 00221007 00221007
Alexander L. Kovalchuk; Wendy DuBois; Elizabeth Mushinski; Nicole E. McNeil; Carsten Hirt; Chen-Feng Qi; Zhaoyang Li; Siegfried Janz; Tasuku Honjo; Masamichi Muramatsu; Thomas Ried; Timothy W. Behrens; Michael Potter
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Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Ting Wang; Jue Zeng; Craig B. Lowe; Robert G. Sellers; Sofie R. Salama; Min Yang; Shawn M. Burgess; Rainer Brachmann; David Haussler
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Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer
Journal of Clinical Oncology, ISSN: 0732183X
Stephen A. Cannistra; Ursula A. Matulonis; Richard T. Penson; Julie Hambleton; Jakob Dupont; Howard M. Mackey; Jeffrey Douglas; Robert. A. Burger; Deborah Armstrong; Robert Wenham; William McGuire
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IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis
Cell, ISSN: 00928674
Eugene Varfolomeev; John W. Blankenship; Sarah M. Wayson; Anna V. Fedorova; Nobuhiko Kayagaki; Parie Garg; Zobel; Jasmin N. Dynek; Linda O. Elliott; Heidi J. A. Wallweber; Flygare; Wayne J. Fairbrother; Deshayes; Vishva M. Dixit; Domagoj Vucic
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The genomic landscapes of human breast and colorectal cancers
Science, ISSN: 00368075 10959203
Laura D. Wood; D. Williams Parsons; Siân Jones; Jimmy Lin; Tobias Sjöblom; Rebecca J. Leary; Dong Shen; Simina M. Boca; Thomas Barber; Janine Ptak; Natalie Silliman; Steve Szabo; Zoltan Dezso; Vadim Ustyanksky; Tatiana Nikolskaya; Yuri Nikolsky; Karchin; Paul A. Wilson; Joshua S. Kaminker; Zemin Zhang; Randal Croshaw; Joseph Willis; Dawn Dawson; Michail Shipitsin; James K. V. Willson; Saraswati Sukumar; Kornelia Polyak; Ben H. Park; Charit L. Pethiyagoda; P. V. Krishna Pant; Dennis G. Ballinger; Andrew B. Sparks; James Hartigan; Douglas R. Smith; Erick Suh; Nickolas Papadopoulos; Phillip Buckhaults; Sanford D. Markowitz; Giovanni Parmigiani; Kenneth W. Kinzler; Victor E. Velculescu; Bert Vogelstein
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Extended follow-up of a phase 3 trial in relapsed multiple myeloma: Final time-to-event results of the APEX trial
Blood, ISSN: 00064971 00064971
Paul Richardson; Pieter Sonneveld; Michael Schuster; Irwin; Edward Stadtmauer; Thierry Facon; Jean-Luc Harousseau; Dina Ben-Yehuda; Sagar Lonial; Hartmut Goldschmidt; Donna Reece; Jesus San Miguel; Joan Bladé; Mario Boccadoro; Jamie Cavenagh; Melissa Alsina; S. Vincent Rajkumar; Martha Lacy; Andrzej Jakubowiak; William Dalton; Anthony Boral; Dixie-Lee Esseltine; David P. Schenkein; Anderson
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Preclinical Safety Evaluation of Biological Oncology Drugs
Preclinical Safety Evaluation of Biopharmaceuticals: A Science-Based Approach to Facilitating Clinical Trials,
Theresa Reynolds
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Science and Judgment in Establishing a Safe Starting Dose for First-in-Human Trials of Biopharmaceuticals
Preclinical Safety Evaluation of Biopharmaceuticals: A Science-Based Approach to Facilitating Clinical Trials,
Jennifer Visich; Rafael Ponce
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Adult spinal cord progenitor cells are repelled by netrin-1 in the embryonic and injured adult spinal cord
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Audrey Petit; Drew L. Sellers; Daniel J. Liebl; Marc Tessier-Lavigne; Timothy E. Kennedy; Philip J. Horner
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Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Sripriya Rajaraman; Jinkuk Choi; Peggie Cheung; Veronica Beaudry; Helen Moore; Steven E. Artandi
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Dendritic cell preactivation impairs MHC class II presentation of vaccines and endogenous viral antigens
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Louise J. Young; Nicholas S. Wilson; Petra Schnorrer; Adele Mount; Rachel J. Lundie; Nicole L. La Gruta; Brendan S. Crabb; Abrielle T. Belz; William R. Heath; Jose A. Villadangos
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High-throughput Generation of Synthetic Antibodies from Highly Functional Minimalist Phage-displayed Libraries
Journal of Molecular Biology, ISSN: 00222836
Frederic A. Fellouse; Kaori Esaki; Sara Birtalan; Demetrios Raptis; Vincenzo J. Cancasci; Akiko Koide; Jhurani; Vasser; Wiesmann; Anthony A. Kossiakoff; Shohei Koide; Sachdev S. Sidhu
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Antiangiogenic therapy for cancer: An update
Cancer Journal (United States), ISSN: 15289117 1540336X
Farbod Shojaei; Napoleone Ferrara
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A high-throughput method for detection of protein self-association and second virial coefficient using size-exclusion chromatography through simultaneous measurement of concentration and scattered light intensity
Pharmaceutical Research, ISSN: 07248741 1573904X
Harminder Bajaj; Vikas Sharma; Devendra S. Kalonia
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C is correct
Lab Animal, ISSN: 00937355 15484475
Gail T. Colbern; Lisa Heath
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Improved vision-related function after ranibizumab treatment of neovascular age-related macular degeneration: Results of a randomized clinical trial
Archives of Ophthalmology, ISSN: 00039950 00039950
Tom S. Chang; Neil M. Bressler; Jennifer T. Fine; Chantal M. Dolan; James Ward; Todd R. Klesert
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Applications of microwave-assisted proteomics in biotechnology
Combinatorial Chemistry and High Throughput Screening, ISSN: 13862073
Wendy N. Sandoval; Victoria Pham; Elizabeth S. Ingle; Peter S. Liu; Jennie R. Lill
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Pharmacokinetics and retinal distribution of ranibizumab, a humanized antibody fragment directed against VEGF-A, following intravitreal administration in rabbits
Retina, ISSN: 0275004X
Jacques Gaudreault; David T.W. Fei; Joseph Beyer; Anne Ryan; Linda Rangell; Vanessa Shiu; Lisa A. Damico
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Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3
Protein Science, ISSN: 09618368 1469896X
Steven T. Runyon; Yingnan Zhang; Brent A. Appleton; Stephen L. Sazinsky; Ping Wu; Borlan Pan; Wiesmann; Nicholas J. Skelton; Sachdev S. Sidhu
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Small-molecule Ghrelin receptor antagonists improve glucose tolerance, suppress appetite, and promote weight loss
Endocrinology, ISSN: 00137227 00137227
William P. Esler; Joachim Rudolph; Thomas H. Claus; Weifeng Tang; Nicole Barucci; Su-Ellen Brown; William Bullock; Michelle Daly; Lynn DeCarr; Yaxin Li; Lucinda Milardo; David Molstad; Jian Zhu; Stephen J. Gardell; James N. Livingston; Laurel J. Sweet
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Role of transporters in the disposition of the selective phosphodiesterase-4 inhibitor (+)-2-[4-({[2-(benzo[1,3]dioxol-5-yloxy)-pyridine- 3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid in rat and human
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Amit S. Kalgutkar; Bo Feng; Hang T. Nguyen; Kosea S. Frederick; Scott D. Campbell; Heather L. Hatch; Yi-An Bi; Diana C. Kazolias; Ralph E. Davidson; Rouchelle J. Mireles; David B. Duignan; Edna F. Choo; Sabrina X. Zhao
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Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence
Molecular and Cellular Biology, ISSN: 02707306
Emmy W. Verschuren; Kenneth H. Ban; Marilyn A. Masek; Norman L. Lehman; Peter K Jackson
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Transmembrane activator and calcium-modulating cyclophilin ligand interactor mutations in common variable immunodeficiency: Clinical and immunologic outcomes in heterozygotes
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Li Zhang; Lin Radigan; Ulrich Salzer; Timothy W. Behrens; Bodo Grimbacher; George Diaz; James B. Bussel; Charlotte Cunningham-Rundles
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Public opinion and smoke-free laws
Policy, Politics, and Nursing Practice, ISSN: 15271544 15527468
Mary Kay Rayens; Ellen J. Hahn; Ronald E. Langley; Susan Hedgecock; Karen M. Butler; Lisa Greathouse-Maggio
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Disruption of E-Cadherin-Mediated Adhesion Induces a Functionally Distinct Pathway of Dendritic Cell Maturation
Immunity, ISSN: 10747613
Aimin Jiang; Ona Bloom; Satoru Ono; Weiguo Cui; Juli Unternaehrer; Shan Jiang; J. Andrew Whitney; John Connolly; Jacques Banchereau; Ira Mellman
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Targeted mass spectrometric strategy for global mapping of ubiquitination on proteins
Rapid Communications in Mass Spectrometry, ISSN: 09514198 10970231
Sahana Mollah; Ingrid E. Wertz; Qui Phung; David Arnott; Vishva M. Dixit; Jennie R. Lill
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Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Judy Qiju Wu; David V. Hansen; Yanxiang Guo; Michael Zhuo Wang; Wanli Tang; Christopher D. Freel; Jeffrey J. Tung; Peter K Jackson; Sally Kornbluth
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Molecular signatures define two main classes of meningiomas
Molecular Cancer, ISSN: 14764598
Lucia Helena Carvalho; Ivan Smirnov; Gilson S. Baia; Zora Modrusan; Justin S. Smith; Peter Jun; Joseph F. Costello; Michael W. McDermott; Scott R. VandenBerg; Anita Lal
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Functional human antigen-specific T cells produced in vitro using retroviral T cell receptor transfer into hematopoietic progenitors
Journal of Immunology, ISSN: 15506606 00221767
Anja U. Van Lent; Maho Nagasawa; Marleen M. Van Loenen; Remko Schotte; Ton N. M. Schumacher; Mirjam H. M. Heemskerk; Hergen Spits; Nicolas Legrand
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Efficacy and safety of single-agent pertuzumab, a human epidermal receptor dimerization inhibitor, in patients with non-small cell lung cancer
Clinical Cancer Research, ISSN: 10780432
Roy S. Herbst; Angela M. Davies; Ronald B. Natale; Thao P. Dang; Joan H. Schiller; Linda L. Garland; Vincent A. Miller; David Mendelson; Annick D. Van Den Abbeele; Yulia Melenevsky; Daniel J. De Vries; Eberhard; Benjamin Lyons; Stuart G. Lutzker; Bruce E. Johnson
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Impact of Delay in Door-to-Needle Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction
American Journal of Cardiology, ISSN: 00029149
Robert L. McNamara; Jeph Herrin; Yongfei Wang; Jeptha P. Curtis; Elizabeth H. Bradley; David J. Magid; Saif S. Rathore; Brahmajee K. Nallamothu; Eric D. Peterson; Martha Blaney; Paul D. Frederick; Harlan M. Krumholz
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The inhibitor of apoptosis proteins as therapeutic targets in cancer
Clinical Cancer Research, ISSN: 10780432
Domagoj Vucic; Wayne J. Fairbrother
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Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide
Nature, ISSN: 14764687 00280836
Roberto Lande; Josh Gregorio; Valeria Facchinetti; Bithi Chatterjee; Yi-Hong Wang; Bernhard Homey; Wei Cao; Yui-Hsi Wang; Bing Su; Frank Nestle; Tomasz Zal; Ira Mellman; Jens-Michael Schröder; Yong-Jun Liu; Michel Gilliet
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Human thymus regeneration and T cell reconstitution
Seminars in Immunology, ISSN: 10445323
Nicolas Legrand; Wendy Dontje; Anja U. Van Lent; Hergen Spits; Bianca Blom
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Applications of multivariate data analysis in biotech processing
BioPharm International, ISSN: 1542166X
Rob Johnson; Oliver Yu; Alime Ozlem Kirdar; Alagappan Annamalai; Sanjeev Ahuja; Kripa Ram; Anurag S. Rathore
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Proteome analysis of antibody-producing CHO cell lines with different metabolic profiles
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Deborah E. Pascoe; David Arnott; Eleftherios T. Papoutsakis; William M. Miller; Dana C. Andersen
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Impact of nonignorable coarsening on Bayesian inference
Biostatistics, ISSN: 14654644 14684357
Jiameng Zhang; Daniel F. Heitjan
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Alpha-v integrins as therapeutic targets in oncology
Cancer Investigation, ISSN: 07357907 15324192
Jeffrey A. Nemeth; Marian T. Nakada; Mohit Trikha; Zhihui Lang; Michael S. Gordon; Gordon C. Jayson; Robert Corringham; Uma Prabhakar; Hugh M. Davis; Robert A. Beckman
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Pharmacokinetics and pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-amino-3{4- [2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4- methylpentanamide, a potent and selective inhibitor of tumor necrosis factor α-converting enzyme in rodents, dogs, chimpanzees, and humans
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Mingxin Qian; Bai; Bernice Brogdon; Jing-Tao Wu; Rui-Qin Liu; Maryanne B. Covington; Kris Vaddi; Robert C. Newton; Michael J. Fossler; C. Edwin Garner; Yuzhong Deng; Thomas Maduskuie; James Trzaskos; James J.-W. Duan; Carl P. Decicco; David D. Christ
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Amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer
Clinical Cancer Research, ISSN: 10780432
Yinghui Guan; Wen-Lin Kuo; Jackie L. Stilwell; Hirokuni Takano; Anna V. Lapuk; Jane Fridlyand; Jian-Hua Mao; Mamie Yu; Melinda A. Miller; Jennifer L. Santos; Steve E. Kalloger; Joseph W. Carlson; David G. Ginzinger; Susan E. Celniker; Gordon B. Mills; David G. Huntsman; Joe W. Gray
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Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis
Genes and Development, ISSN: 08909369 15495477
Bruno Larrivee; Catarina Freitas; Marc Trombe; Xiang Lv; Benjamin DeLafarge; Li Yuan; Karine Bouvrée; Christiane Bréant; Raquel del Toro; Nicolas Bréchot; Stéphane Germain; Françoise Bono; Frédérique Dol; Filip Claes; Christian Fischer; Monica Autiero; Jean-Léon Thomas; Peter Carmeliet; Marc Tessier-Lavigne; Anne Eichmann
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