Genentech: Publications

July 29, 2005

Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy

Biochemical and Biophysical Research Communications, ISSN: 0006291X

Napoleone Ferrara; Kenneth J. Hillan; Novotny

July 25, 2005

Quality of care by classification of myocardial infarction. Treatment patterns for ST-segment elevation vs non-ST-segment elevation myocardial infarction

Archives of Internal Medicine, ISSN: 00039926

Matthew T. Roe; Lori Parsons; Charles V. Pollack Jr.; John G. Canto; Hal V. Barron; Nathan R. Every; William J. Rogers; Eric D. Peterson

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July 15, 2005

IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-γ responses if IL-12p70 is available

Journal of Immunology, ISSN: 00221767

Shabaana A. Khader; John E. Pearl; Kaori Sakamoto; Leigh Gilmartin; Guy Bell; Dawn M. Jelley-Gibbs; Nico Ghilardi; Frederic J. De Sauvage; Andrea M. Cooper

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July 15, 2005

EphB2 is a prognostic factor in colorectal cancer

Clinical Cancer Research, ISSN: 10780432

Adrian M. Jubb; Fiona Zhong; Sheila Bheddah; Grabsch; Gretchen D. Frantz; Wolfram Mueller; Kavi; Philip Quirke; Paul G. Polakis; Koeppen

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July 14, 2005

Common mechanisms of nerve and blood vessel wiring

Nature, ISSN: 00280836

Peter Carmeliet; Marc Tessier-Lavigne

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July 13, 2005

Perceptions of positive meaning and vulnerability following breast cancer: Predictors and outcomes among long-term breast cancer survivors

Annals of Behavioral Medicine, ISSN: 08836612

Julienne E. Bower; Beth E. Meyerowitz; Katherine A. Desmond; Coen A. Bernaards; Julia H. Rowland; Patricia A. Ganz

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July 1, 2005

Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab

Journal of the National Cancer Institute, ISSN: 00278874 14602105

William Ince; Adrian M. Jubb; Scott N. Holden; Holmgren; Tobin; Meera Sridhar; Herbert Hurwitz; Fairooz F. Kabbinavar; Novotny; Kenneth J. Hillan; Koeppen

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July 1, 2005

Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab

Journal of the National Cancer Institute, ISSN: 00278874 14602105

William L. Ince; Adrian M. Jubb; Scott N. Holden; Holmgren; Tobin; Meera Sridhar; Herbert Hurwitz; Fairooz F. Kabbinavar; Novotny; Kenneth J. Hillan; Koeppen

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July 1, 2005

Multimodality expression profiling shows SEPT9 to be overexpressed in a wide range of human tumours

Oncogene, ISSN: 09509232

Michael Scott; Paula L. Hyland; Gordon McGregor; Kenneth J. Hillan; S. E. Hilary Russell; Peter A. Hall

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July 1, 2005

Expression profiling the human septin gene family

Journal of Pathology, ISSN: 00223417

Peter A. Hall; Kenneth Jung; Kenneth J. Hillan; S. E. Hilary Russell

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July 1, 2005

Gene polymorphisms and serological markers of patients with active Crohn's disease in a clinical trial of antisense to ICAM-1

Clinical and Experimental Immunology, ISSN: 00099104

Bruce R. Yacyshyn; Schievella; Sewell; Tami

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July 1, 2005

Genentech error proofs its batch records

Quality Progress, ISSN: 0033524X

Robert Bottome; Richard C. H. Chua

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July 1, 2005

Role of efflux pumps and metabolising enzymes in drug delivery

Expert Opinion on Drug Delivery, ISSN: 17425247

Suresh Katragadda; Balasubrahmanyam Budda; Banmeet S. Anand; Ashim K. Mitra

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July 1, 2005

Angiogenesis is required for successful bone induction during distraction osteogenesis

Journal of Bone and Mineral Research, ISSN: 08840431

Tony D. Fang; Ali Salim; Wei Xia; Randall P. Nacamuli; Samira Guccione; Hanjoon M. Song; Richard A. D. Carano; Ellen H. Filvaroff; Mark D. Bednarski; Amato J. Giaccia; Michael T. Longaker

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July 1, 2005

Airway generation-specific differences in the spatial distribution of immune cells and cytokines in allergen-challenged rhesus monkeys

Clinical and Experimental Allergy, ISSN: 09547894

Lisa A. Miller; Stephen D. Hurst; Coffman; Tyler; Stovall; Chou; Lei F. Putney; Gershwin; Edward S. Schelegle; Plopper; Dallas M. Hyde

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July 1, 2005

Vascular endothelial growth factor co-ordinates proper development of lung epithelium and vasculature

Mechanisms of Development, ISSN: 09254773

Liqing Zhao; Ke Wang; Napoleone Ferrara; Thiennu H. Vu

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July 1, 2005

Transcriptional regulatory networks activated by PI3K and ERK transduced growth signals in human glioblastoma cells

Journal of Computer Science and Technology, ISSN: 10009000

Matthias Peter; Zhi-Ping Weng; Ulla Hansen

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July 1, 2005

Pharmacokinetic-pharmacodynamic-efficacy analysis of efalizumab in patients with moderate to severe psoriasis

Pharmaceutical Research, ISSN: 07248741 1573904X

Chee Ng; Amita Joshi; Russell L Dedrick; Marvin Garovoy; Bauer

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July 1, 2005

Population pharmacokinetics of rituximab (anti-CD20 monoclonal antibody) in rheumatoid arthritis patients during a phase II clinical trial

Journal of Clinical Pharmacology, ISSN: 00912700

Chee Ng; Rene Bruno; Dan Combs; Brian E. Davies

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July 1, 2005

Vertebrate GLD2 poly(A) polymerases in the germline and the brain

RNA, ISSN: 13558382

Labib Rouhana; Liaoteng Wang; Natascha Buter; Eun Kwak Jae; Craig A. Schiltz; Gonzalez; Ann E. Kelley; Charles F. Landry; Marvin Wickens

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June 30, 2005

A method to estimate the variance of an endpoint from an on-going blinded trial

Statistics in Medicine, ISSN: 02776715

Biao Xing; Jitendra Ganju

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June 17, 2005

Performance of a membrane adsorber for trace impurity removal in biotechnology manufacturing

Journal of Chromatography A, ISSN: 00219673

Michael Phillips; Jason Cormier; Jennifer Ferrence; Chris Dowd; Robert Kiss; Herbert Lutz; Jeffrey Carter

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June 15, 2005

Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase

EMBO Journal, ISSN: 02614189

Rongsheng Jin; Jagath R. Junutula; Hugo T. Matern; Karen E. Ervin; Richard H. Scheller; Axel T. Brünger

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June 15, 2005

Positive and negative regulation of the IL-27 receptor during lymphoid cell activation

Journal of Immunology, ISSN: 00221767

Alejandro V. Villarino; Joseph Larkin III; Christiaan J. M. Saris; Andrew J. Caton; Sophie Lucas; Wong; Frederic J. De Sauvage; Christopher A. Hunter

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June 1, 2005

Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region

Development (Cambridge), ISSN: 09501991

Maxime Bouchard; David Grote; Sarah E. Craven; Qiong Sun; Peter Steinlein; Meinrad Busslinger

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June 1, 2005

Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib

Journal of the National Cancer Institute, ISSN: 00278874 14602105

Daphne A. Haas-Kogan; Michael D. Prados; Tarik Tihan; Eberhard; Nannette Jelluma; Nils D. Arvold; Rachel Baumber; Kathleen R. Lamborn; Ami Kapadia; Mary Malec; Mitchel S. Berger; David Stokoe

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June 1, 2005

Racial differences in reperfusion therapy use in patients hospitalized with myocardial infarction: A regional phenomenon

American Heart Journal, ISSN: 00028703

Saif S. Rathore; Paul D. Frederick; Nathan R. Every; Hal V. Barron; Harlan M. Krumholz

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June 1, 2005

Estimating heterogeneity in random effects models for longitudinal data

Biometrical Journal, ISSN: 03233847

Annabelle Lemenuel-Diot; Mallet; Laveille; Rene Bruno

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June 1, 2005

Tumor immunity via homeostatic T cell proliferation: Mechanistic aspects and clinical perspectives

Springer Seminars in Immunopathology, ISSN: 03444325

Roberto Baccala; Rosana Gonzalez-Quintial; Wolfgang Dummer; Argyrios N. Theofilopoulos

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June 1, 2005

Immune response in silico (IRIS): Immune-specific genes identified from a compendium of microarray expression data

Genes and Immunity, ISSN: 14664879

Abbas Alexander; Daryl T. Baldwin; Yan Ma; Wenjun Ouyang; Austin L. Gurney; Flavius Martin; Sherman Fong; Menno Van Lookeren Campagne; Godowski; P. Mickey Williams; Andrew A. Chan; Hilary F. Clark

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June 1, 2005

Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering

Immunity, ISSN: 10747613

Sofia Z. Raptis; Steven D. Shapiro; Pamela M. Simmons; Alec M. Cheng; Christine T.N. Pham

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June 1, 2005

Immune response in silico (IRIS): Immune-specific genes identified from a compendium of microarray expression data

Genes and Immunity, ISSN: 14664879

Abbas Alexander; Daryl T. Baldwin; Yan Ma; Wenjun Ouyang; Austin L. Gurney; Flavius Martin; Fong; Menno Van Lookeren Campagne; Godowski; P. Mickey Williams; Andrew A. Chan; Hilary F. Clark

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May 27, 2005

Multiplexed serum measurement of IgG, IgA, IgM, and IgE antibody responses to therapeutic biologicals

Immunological Investigations, ISSN: 08820139

Krista McCutcheon; Edward O'Hara; David T.W. Fei

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May 20, 2005

Evaluation of different primary recovery methods for E. coli-derived recombinant human growth hormone and compatibility with further down-stream purification

Biotechnology and Bioengineering, ISSN: 00063592

Josefine Persson; Dana C. Andersen; Philip M. Lester

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May 20, 2005

Molecular recognition by a binary code

Journal of Molecular Biology, ISSN: 00222836

Frederic A. Fellouse; Bing Li; Deanne M. Compaan; Andrew A. Peden; Sarah G. Hymowitz; Sachdev S. Sidhu

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May 15, 2005

An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin

Cancer Research, ISSN: 00085472

Richard W. Tothill; Adam Kowalczyk; Danny Rischin; Alex Bousioutas; Izhak Haviv; Ryan K. Van Laar; Waring; John Zalcberg; Robyn Ward; Andrew V. Biankin; Robert L. Sutherland; Susan M. Henshall; Kwun Fong; Jonathan R. Pollack; David D.L. Bowtell; Andrew J. Holloway

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May 13, 2005

Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis

Journal of Biological Chemistry, ISSN: 00219258

Darcie Sharp; David Lawrence; Avi Ashkenazi

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May 6, 2005

A structure-based database of antibody variable domain diversity

Journal of Molecular Biology, ISSN: 00222836

Christopher J. Bond; Wiesmann; James C. Marsters Jr.; Sachdev S. Sidhu

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May 1, 2005

Tissue distribution and receptor-mediated clearance of anti-CD11a antibody in mice

Drug Metabolism and Disposition, ISSN: 00909556

Greg P. Coffey; Judy Fox; Susanne Pippig; Susan Palmieri; Barbara Reitz; Michelle Gonzales; Anahid Bakshi; Josette Padilla-Eagar; Fielder

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May 1, 2005

Novel brain wiring functions for classical morphogens: A role as graded positional cues in axon guidance

Development (Cambridge), ISSN: 09501991

Frédéric Charron; Marc Tessier-Lavigne

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May 1, 2005

A novel E3 ubiquitin ligase TRAC-1 positively regulates T cell activation

Journal of Immunology, ISSN: 00221767

Haoran Zhao; Connie C. Li; Jorge Pardo; Peter C. Chu; Charlene X. Liao; Jianing Huang; John G. Dong; Xiulan Zhou; Qi Huang; Betty Huang; Mark K. Bennett; Susan M. Molineaux; Henry Lu; Sarkiz Daniel-Issakani; Donald G. Payan; Esteban S. Masuda

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May 1, 2005

A monoclonal antibody that inhibits mouse tissue factor function [7]

Journal of Thrombosis and Haemostasis, ISSN: 15387933 15387836

Daniel Kirchhofer; Paul Moran; Sherron L. Bullens; Franklin V. Peale Jr.; Bunting

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May 1, 2005

GMAP: A genomic mapping and alignment program for mRNA and EST sequences

Bioinformatics, ISSN: 13674803

Thomas D Wu; Colin K. Watanabe

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May 1, 2005

Disulfide locked variants of factor VIIa with a restricted β-strand conformation have enhanced enzymatic activity

Protein Science, ISSN: 09618368

Henry R. Maun; Eigenbrot; Helga Raab; David Arnott; Lilian Phu; Sherron L. Bullens; Lazarus

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May 1, 2005

PAK4 mediates morphological changes through the regulation of GEF-H1

Journal of Cell Science, ISSN: 00219533

Marinella G. Callow; Sergey Zozulya; Mikhail L. Gishizky; Bahija Jallal; Tod Smeal

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May 1, 2005

Synthetic lethality of retinoblastoma mutant cells in the Drosophila eye by mutation of a novel peptidyl prolyl isomerase gene

Genetics, ISSN: 00166731

Kyle A. Edgar; Marcia Belvin; Annette L. Parks; Kellie Whittaker; Matt B. Mahoney; Monique Nicoll; Christopher C. Park; Christopher G. Winter; Feng Chen; Kim Lickteig; Ferhad Ahmad; Hanife Esengil; Matthew V. Lorenzi; Amanda Norton; Brent A. Rupnow; Laleh Shayesteh; Mariano Tabios; Lynn M. Young; Pamela M. Carroll; Casey Kopczynski; Greg D. Plowman; Lori S. Friedman; Helen L. Francis-Lang

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May 1, 2005

Tenecteplase in the treatment of thrombosed hemodialysis grafts

CardioVascular and Interventional Radiology, ISSN: 01741551

Abigail Falk; Kathy Harbour

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April 26, 2005

Comparison of the global structure and dynamics of native and unmodified tRNAval

Biochemistry, ISSN: 00062960

Annaleen Vermeulen; Scott A. McCallum; Arthur Pardi

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April 25, 2005