Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12351 - 12400 OF 15658 RESULTS

Use of infrared spectroscopy to assess secondary structure of human growth hormone within biodegrable microspheres
Journal of Pharmaceutical Sciences, ISSN: 00223549
Tzung-Horng Yang; Aichun Dong; Jeffrey D. Meyer; OluFunmi Johnson; Cleland; John F. Carpenter
View on Scopus
Thrombopoietin (Tpo) in the fetus and neonate: Tpo concentrations in preterm and term neonates, and organ distribution of Tpo and its receptor (c-mpl) during human fetal development
Early Human Development, ISSN: 03783782
Martha C. Sola; Sandra E. Juul; Meng; Shaily Garg; Paul Sims; Darlene A. Calhoun; J. Benjamin Dame; Robert D. Christensen
View on Scopus
Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases
Brazilian Journal of Medical and Biological Research, ISSN: 1414431X 0100879X
Belizário; Steve Sherwood; Beçak
View on Scopus
Role of baseline parameters in determining indirect pharmacodynamic responses
Journal of Pharmaceutical Sciences, ISSN: 00223549
Yu-Nien Sun; William J. Jusko
View on Scopus
Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease
Liver, ISSN: 01069543
Kenneth J. Hillan; Kelly E. Hagler; Roderick N. M. MacSween; Anne Ryan; Renz; Chiu; Rod K. Ferrier; George L. Bird; Amar P. Dhillon; Linda D. Ferrell; Fong
View on Scopus
Novel peptides selected to bind vascular endothelial growth factor target the receptor-binding site
Biochemistry, ISSN: 00062960
Wayne J. Fairbrother; Hans W. Christinger; Andrea G Cochran; Fuh; Christopher J. Keenan; Quan; Stephanie K. Shriver; Jeffrey Tom; James A. Wells; Cunningham
View on Scopus
Crystal structure of the complex between VEGF and a receptor-blocking peptide
Biochemistry, ISSN: 00062960
Wiesmann; Hans W. Christinger; Andrea G Cochran; Cunningham; Wayne J. Fairbrother; Christopher J. Keenan; Meng; De Vos
View on Scopus
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer
Nature, ISSN: 00280836
Pitti; Scot A. Marsters; David Lawrence; Margaret Roy; Frank C. Kischkel; Patrick Dowd; Arthur Huang; Christopher J. Donahue; Steve Sherwood; Daryl T. Baldwin; Godowski; William I. Wood; Austin L. Gurney; Kenneth J. Hillan; Robert L. Cohen; Goddard; David Botstein; Avi Ashkenazi
View on Scopus
Safety and immunogenicity of HIV recombinant envelope vaccines in HIV- infected infants and children
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, ISSN: 10779450
John S. Lambert; James McNamara; Samuel L. Katz; Terry Fenton; Minhee Kang; Thomas C. VanCott; Robert Livingston; Elizabeth Hawkins; Jack Moye Jr.; William Borkowsky; Daniel Johnson; Ram Yogev; A-M. Duliege; Francis; Anne Gershon; Diane W. Wara; Natasha L. Martin; Myron Levin; George McSherry; Gale Smith
View on Scopus
Crystal structure of the MATa1/MATα2 homeodomain heterodimer in complex with DNA containing an A-tract
Nucleic Acids Research, ISSN: 03051048
Thomas Li; Yisheng Jin; Andrew K. Vershon; Cynthia Wolberger
View on Scopus
Host defense molecule polymorphisms influence the risk for immune- mediated complications in chronic granulomatous disease
Journal of Clinical Investigation, ISSN: 00219738
Charles B. Foster; Thomas Lehrnbecher; Femke Mol; Seth M. Steinberg; David J. Venzon; Thomas J. Walsh; Noack; Julie Rae; Jerry A. Winkelstein; John T. Curnutte; Stephen J. Chanock
View on Scopus
Compendium of excipients for parenteral formulations
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
Powell; Tue H. Nguyen; Baloian
View on Scopus
Probing the importance of second sphere residues in an esterolytic antibody by phage display
Journal of Molecular Biology, ISSN: 00222836
Michelle R. Arkin; James A. Wells
View on Scopus
Triplet energy transfer through the walls of hemicarcerands: Temperature dependence and the role of internal reorganization energy
Journal of the American Chemical Society, ISSN: 00027863
Ileana Place; Angeles Farran; Deshayes; Piotrowiak
View on Scopus
WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Diane Pennica; Todd A. Swanson; James W. Welsh; Margaret Roy; David Lawrence; James Lee; Brush; Lisa A. Taneyhill; Bethanne Deuel; Michael Lew; Colin K. Watanabe; Robert L. Cohen; Mona F. Melhem; Gene G. Finley; Philip Quirke; Goddard; Kenneth J. Hillan; Austin L. Gurney; David Botstein; Arnold J. Levine
View on Scopus
Chinese hamster ovary cells with constitutively expressed sialidase antisense RNA produce recombinant DNase in batch culture with increased sialic acid
Biotechnology and Bioengineering, ISSN: 00063592
Ferrari; Jane Gunson; James A. Lofgren; Lynne Krummen; Warner
View on Scopus
Real-time control of purified product collection during chromatography of recombinant human insulin-like growth factor-I using an on-line assay
Journal of Chromatography A, ISSN: 00219673
Fahrner; Philip M. Lester; Gregory S. Blank; David H. Reifsnyder
View on Scopus
Conformations of thioamide-containing dipeptides: A computational study
Journal of the American Chemical Society, ISSN: 00027863
Dean R. Artis; Mark A. Lipton
View on Scopus
Transfer of a protein binding epitope to a minimal designed peptide
Biopolymers - Peptide Science Section, ISSN: 00063525
Quan; Nicholas J. Skelton; Clark; Jackson; Renz; Chiu; Keating; Beresini; Sherman Fong; Dean R. Artis
View on Scopus
Treatment of indolent lymphoma with fludarabine/mitoxantrone combination: A phase II trial
Hematological Oncology, ISSN: 02780232
Christos Emmanouilides; Peter Rosen; Sara Rasti; Mary Territo; Lori Kunkel
View on Scopus
The specification of sympathetic neurotransmitter phenotype depends on gp130 cytokine receptor signaling
Development (Cambridge), ISSN: 09501991
Markus Geissen; Stefan Heller; Diane Pennica; Uwe Ernsberger; Hermann Rohrer
View on Scopus
Development of V3-loop pseudomonas exotoxin chimeras: Candidate vaccines for human immunodeficiency virus-1
FASEB Journal, ISSN: 08926638
David FitzGerald; Charlotte M. Fryling; Marian McKee; Ann L. Danghcrty; Randall J. Mj-sny
View on Scopus
Acetogenesis does not replace ketogenesis in fasting piglets infused with hexanoate
American Journal of Physiology, ISSN: 00029513
Adams; Jack Odle
View on Scopus
Mucosal administration of a non-toxic pseudomonas exotoxin-gpllo V3 loop chimera elevates gpllO specific IgG and IgA in the serum and saliva of balb/c mice
FASEB Journal, ISSN: 08926638
Daugherty; Suva; Charlotte M. Fryling; David FitzGerald; Mrsny
View on Scopus
Fast Edman cycles with accelerated PTH analysis
Protein Journal, ISSN: 15723887 15734943
William J. Henzel; Jake Tropea; Kishiyama; Wendy Shillinglaw; David Dupont; Steve O'Neil
View on Scopus
Dose-dependence and repeated-dose studies for receptor/gene-mediated pharmacodynamics of methylprednisolone on glucocorticoid receptor down- regulation and tyrosine aminotransferase induction in rat liver
Journal of Pharmacokinetics and Biopharmaceutics, ISSN: 0090466X
Sun; Debra C. DuBois; Richard R. Almon; Nancy A. Pyszczynski; William J. Jusko
View on Scopus
A carboxypeptidase inhibitor markedly improves the potency of tPA in-vivo
Fibrinolysis and Proteolysis, ISSN: 13690191
Refino; Schmitt; Cheryl Pater; Bunting
View on Scopus
7 Ty Mutagenesis
Methods in Microbiology, ISSN: 05809517
David J. Garfinkel; M. Joan Curcio; Victoria Smith
View on Scopus
Dose-dependence and repeated-dose studies for receptor/gene-mediated pharmacodynamics of methylprednisolone on glucocorticoid receptor down- regulation and tyrosine aminotransferase induction in rat liver
Journal of Pharmacokinetics and Biopharmaceutics, ISSN: 0090466X
Yu-Nien Sun; Debra C. DuBois; Richard R. Almon; Nancy A. Pyszczynski; William J. Jusko
View on Scopus
Transfer of a protein binding epitope to a minimal designed peptide
Biopolymers - Peptide Science Section, ISSN: 00063525
Quan; Nicholas J. Skelton; Clark; Jackson; Renz; Chiu; Keating; Beresini; Fong; Dean R. Artis
View on Scopus
Analysis of repeated markers used to predict progression of cancer
Statistics in Medicine, ISSN: 02776715
Birol Emir; Sam Wieand; John Q. Su; Steve Cha
View on Scopus
The Drosophila inhibitor of apoptosis D-IAP1 suppresses cell death induced by the caspase drICE
FEBS Letters, ISSN: 00145793
William J. Kaiser; Domagoj Vucic; Lois K. Miller
View on Scopus
A transient expansion of the native state precedes aggregation of recombinant human interferon-γ
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Brent Kendrick; John F. Carpenter; Cleland; Theodore W. Randolph
View on Scopus
Translocation of human calcitonin in respiratory nasal epithelium is associated with self-assembly in lipid membrane
Biochemistry, ISSN: 00062960
M. Christiane Schmidt; Barbara Rothen-Rutishauser; Beate Rist; Annette Beck-Sickinger; Heidi Wunderli-Allenspach; Rubas; Wolfgang Sadée; Hans P. Merkle
View on Scopus
Crystal structure of the NK1 fragment of human hepatocyte growth factor at 2.0 Å resolution
Structure, ISSN: 09692126
Ultsch; Lokker; Godowski; De Vos
View on Scopus
Metabolic consequences of 5-year growth hormone (GH) therapy in children treated with GH for idiopathic short stature
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Saenger; Kenneth M. Attie; Dimartino-Nardi; Hintz; Frahm; James W. Frane; Ann J. Johanson; Joyce Baptista; Joyce Kuntze; Robert M. Blizzard; Cara; Chernausek; Geffner; Gertner; Hopwood; Kaplan; Barbara M. Lippe; Plotnick; Alan D. Rogol
View on Scopus
Changes in thyroid hormone levels during growth hormone therapy in initially euthyroid patients: Lack of need for thyroxine supplementation
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
David T. Wyatt; Gesundheit; Barry M. Sherman
View on Scopus
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway: Requirement for Flk-1/KDR activation
Journal of Biological Chemistry, ISSN: 00219258
Hans-Peter Gerber; Amy E. McMurtrey; Joe Kowalski; Minhong Yan; Keyt; Vishva M. Dixit; Napoleone Ferrara
View on Scopus
PSTPIP 2, a second tyrosine phosphorylated, cytoskeletal-associated protein that binds a PEST-type protein-tyrosine phosphatase
Journal of Biological Chemistry, ISSN: 00219258
Yan Wu; Dowbenko; Lasky
View on Scopus
Protein targeting in the analysis of learning and memory: A potential alternative to gene targeting
Experimental Brain Research, ISSN: 00144819
Gerlai; Simon P. Williams; Cairns; Nicholas Van Bruggen; Paul Moran; Shih; Caras; Hans Sauer; Phillips; Winslow
View on Scopus
Corticotropin regulates vascular endothelial growth factor expression in human fetal adrenal cortical cells
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Jan L. Shifren; Sam Mesiano; Robert N. Taylor; Napoleone Ferrara; Robert B. Jaffe
View on Scopus
Blunted thrombopoietin response to interferon alfa-induced thrombocytopenia during treatment for hepatitis C
Hepatology, ISSN: 02709139
Markus Peck-Radosavljevic; Martina Wichlas; Johann Pidlich; Paul Sims; Meng; Johannes Zacherl; Shaily Garg; Christian Datz; Alfred Gangl; Peter Ferenci
View on Scopus
Characterization of two patched receptors for the vertebrate hedgehog protein family
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
David Carpenter; Donna Stone; Brush; Anne Ryan; Armanini; Gretchen D. Frantz; Rosenthal; Frederic J. De Sauvage
View on Scopus
Nuclear integration of glucocorticoid receptor and nuclear factor-κB signaling by CREB-binding protein and steroid receptor coactivator-1
Journal of Biological Chemistry, ISSN: 00219258
Kelly-Ann Sheppard; Kathleen M. Phelps; Amy J. Williams; Dimitris Thanos; Christopher K. Glass; Michael G. Rosenfeld; Mary E. Gerritsen; Tucker Collins
View on Scopus
Homologous up-regulation of KDR/Flk-1 receptor expression by vascular endothelial growth factor in vitro
Journal of Biological Chemistry, ISSN: 00219258
Shen; David Y. Lee; Hans-Peter Gerber; Keyt; Napoleone Ferrara; Zioncheck
View on Scopus
Caspase-14 is a novel developmentally regulated protease
Journal of Biological Chemistry, ISSN: 00219258
Shimin Hu; Scott J. Snipas; Claudius Vincenz; Guy S. Salvesen; Vishva M. Dixit
View on Scopus
Spray-drying performance of a bench-top spray dryer for protein aerosol powder preparation
Biotechnology and Bioengineering, ISSN: 00063592
Maa; Phuong-Anh Nguyen; Kin Sit; Chung C. Hsu
View on Scopus
Scythe: A novel reaper-binding apoptotic regulator
EMBO Journal, ISSN: 02614189
Kenneth Thress; William J. Henzel; Wendy Shillinglaw; Sally Kornbluth
View on Scopus
Expression of novel potassium channels in the chick basilar papilla
Hearing Research, ISSN: 03785955
Karen Mason; Franklin V. Peale Jr.; Jennifer S. Stone; Edwin W Rubel; Bothwell
View on Scopus
A His19 to Ala mutant of melanoma growth-stimulating activity is a partial antagonist of the CXCR2 receptor
Journal of Immunology, ISSN: 00221767
Deborah L. Baly; Richard Horuk; Yansura; Laura C. Simmons; Wayne J. Fairbrother; Claire Kotts; Wirth; Beth Gillece-Castro; Toy; Joseph Hesselgesser; David E. Allison
View on Scopus
© 2025 Genentech, Inc. All rights reserved. This site is intended for US residents only.