Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 3651 - 3700 OF 15805 RESULTS

Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins
eLife, ISSN: 2050084X
Junghyun Lim; Hyunjoo Park; Jason Heisler; Timurs Maculins; Merone Roose-Girma; Min Xu; Brent Mckenzie; Menno Van Lookeren Campagne; Kim Newton; Aditya Murthy
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An IQ Consortium Perspective on The Scientific Committee on Health, Environmental and Emerging Risks Final Opinion on the Need for Nonhuman Primates in Biomedical Research, Production and Testing of Products and Devices (Update 2017)
Toxicologic Pathology, ISSN: 15331601 01926233
Khary Adams; Donna Clemons; Lynn Collura Impelluso; Donna W. Lee; Sean Maguire; Alexis Myers; Christopher Petursson; Robert J. Schulingkamp; Kevin Trouba; Matthew Wright
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Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
Nature Methods, ISSN: 15487105 15487091
Glenn R. Masson; John E. Burke; Natalie G. Ahn; Ganesh Srinivasan Anand; Christoph H. Borchers; Sébastien Brier; George M. Bou-Assaf; John R. Engen; S. Walter Englander; Johan Faber; Rachel Garlish; Patrick Griffin; Michael L. Gross; Miklos Guttman; Yoshitomo Hamuro; Albert J.R. Heck; Damian Houde; Roxana E. Iacob; Thomas J. D. Jørgensen; Igor A. Kaltashov; Judith P. Klinman; Lars Konermann; Petr Man; Leland Mayne; Bruce D. Pascal; Dana Reichmann; J. Mark Skehel; Joost Snijder; Timothy S. Strutzenberg; Eric S. Underbakke; Cornelia Wagner; Thomas E. Wales; Benjamin T. Walters; David D. Weis; Derek J. Wilson; Patrick L. Wintrode; Zhongqi Zhang; Jie Zheng; David C. Schriemer; Kasper D. Rand
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Pirfenidone in patients with idiopathic pulmonary fibrosis and more advanced lung function impairment
Respiratory Medicine, ISSN: 15323064 09546111
Steven D Nathan; Ulrich Costabel; Carlo Albera; Jürgen Behr; Wim Wuyts; Klaus-Uwe Kirchgaessler; John L. Stauffer; Elizabeth A. Morgenthien; Willis Chou; Susan L. Limb; Paul W. Noble
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Atezolizumab in combination with carboplatin plus nab-paclitaxel chemotherapy compared with chemotherapy alone as first-line treatment for metastatic non-squamous non-small-cell lung cancer (IMpower130): a multicentre, randomised, open-label, phase 3 trial
The Lancet Oncology, ISSN: 14745488 14702045
Howard West; Michael McCleod; Maen Hussein; Alessandro Morabito; Achim Rittmeyer; Henry J Conter; Hans-Georg Kopp; Davey B Daniel; Steven McCune; Tarek Mekhail; Alona Zer; Niels Reinmuth; Ahad Sadiq; Alan Sandler; Wei Lin; Tania Ochi Lohmann; Venice Archer; Lijia Wang; Marcin Kowanetz; Federico Cappuzzo
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Polatuzumab vedotin in combination with immunochemotherapy in patients with previously untreated diffuse large B-cell lymphoma: an open-label, non-randomised, phase 1b–2 study
The Lancet Oncology, ISSN: 14745488 14702045
Herve Tilly; Morschhauser; Nancy L. Bartlett; Amitkumar Mehta; Gilles Salles; Corinne Haioun; Javier Munoz; Chen; Kathryn S. Kolibaba; Dan Lu; Mark Yan; Elicia M. Penuel; Jamie Hirata; Calvin Lee; Jeff P. Sharman
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Prognostic risk score for patients with relapsed or refractory chronic lymphocytic leukaemia treated with targeted therapies or chemoimmunotherapy: a retrospective, pooled cohort study with external validations
The Lancet Haematology, ISSN: 23523026
Jacob D Soumerai; Ai Ni; Mohamed Darif; Anil Londhe; Guan Xing; Yong Mun; Neil E Kay; Tait D Shanafelt; Kari G Rabe; John C. Byrd; Chanan-Khan; Richard Furman; Hillmen; Jeffrey Jones; John F. Seymour; Jeff P. Sharman; Lucille Ferrante; Mehrdad Mobasher; Thomas Stark; Vijay Reddy; Lyndah K Dreiling; Pankaj Bhargava; Angela Howes; Danelle F James; Zelenetz
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ISPOR, the FDA, and the Evolving Regulatory Science of Medical Device Products
Value in Health, ISSN: 15244733 10983015
Tyler O'Neill; Rebecca Miksad; Danelle Miller; Lesley Maloney; Ani John; Carolyn Hiller; John Hornberger
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Effect of concomitant dosing with acid-reducing agents and vemurafenib dose on survival in patients with BRAFV600 mutation–positive metastatic melanoma treated with vemurafenib ± cobimetinib
European Journal of Cancer, ISSN: 18790852 09598049
Karl Lewis; Axel Hauschild; James Larkin; Antoni Ribas; Keith Flaherty; McArthur; Brigitte Dréno; Edward McKenna; Qian Zhu; Yong Mun; Paolo A. Ascierto
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Pharmacokinetics of trastuzumab emtansine (T-DM1) as a single agent or in combination with pertuzumab in HER2-positive breast cancer patients with recurrent or locally advanced metastatic breast cancer
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Dan Lu; Chunze Li; Matthew Riggs; Daniel Polhamus; Jonathan French; Priya Agarwal; Shang-Chiung Chen; Shweta Vadhavkar; Patre; Alexander Strasak; Angelica Quartino; Jin Yan Jin; Sandhya Girish
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Assessment of Biopharmaceutical Performance of Supersaturating Formulations of Carbamazepine in Rats Using Physiologically Based Pharmacokinetic Modeling
AAPS PharmSciTech, ISSN: 15309932
Samarth D. Thakore; Poonam Singh Thakur; Ganesh Shete; Rahul Gangwal; Ajit S. Narang; Abhay T. Sangamwar; Arvind Kumar Bansal
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Imaging, Genetic, and Demographic Factors Associated with Conversion to Neovascular Age-Related Macular Degeneration: Secondary Analysis of a Randomized Clinical Trial
JAMA Ophthalmology, ISSN: 21686165
Joelle A. Hallak; Luis De Sisternes; Aaron Osborne; Brian L. Yaspan; Daniel L. Rubin; Theodore Leng
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A 2-Year Observational Study in Patients Suffering from Idiopathic Pulmonary Fibrosis and Treated with Pirfenidone: A French Ancillary Study of PASSPORT
Respiration, ISSN: 14230356 00257931
Stéphane Jouneau; Anne-Sophie Gamez; Julie Traclet; Hilario Nunes; Sylvain Marchand-Adam; Romain Kessler; Dominique Israël-Biet; Raphael Borie; Indiana Strombom; Astrid Scalori; Bruno Crestani; Dominique Valeyre; Vincent Cottin
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Does In Vitro Cytochrome P450 Downregulation Translate to In Vivo Drug-Drug Interactions? Preclinical and Clinical Studies With 13-cis-Retinoic Acid
Clinical and Translational Science, ISSN: 17528062 17528054
Faith Stevison; Mika Kosaka; Jane R. Kenny; Susan C. Wong; Cathryn Hogarth; John K. Amory; Nina Isoherranen
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Interindividual and Regional Variability in Drug Transporter Abundance at the Human Blood–Brain Barrier Measured by Quantitative Targeted Proteomics
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Sarah Billington; Laurent Salphati; Cornelis E. Hop; Xiaoyan Chu; Raymond Evers; Doug Burdette; Christopher Rowbottom; Yurong Lai; Guangqing Xiao; W. Griffith Humphreys; Tot Bui Nguyen; Bhagwat Prasad; Jashvant D. Unadkat
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An Integrated Analysis of Solid Form Change Impact on Solubility and Permeability: Case Study of Oral Exposure in Rats of an RAR Related Orphan Receptor C Inhibitor
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Po-Chang Chiang; Karthik Nagapudi; Jia Liu; James J. Crawford; Jason R. Zbieg; Emile G. Plise; Yuzhong Deng
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Phase II Randomized Trial of Sequential or Concurrent FOLFOXIRI-Bevacizumab Versus FOLFOX-Bevacizumab for Metastatic Colorectal Cancer (STEAM)
Oncologist, ISSN: 1549490X 10837159
Herbert Hurwitz; Benjamin R. Tan; James A. Reeves; Henry Xiong; Bradley Somer; Heinz-Josef Lenz; Hochster; Frank A. Scappaticci; John F. Palma; Richard Price; John J. Lee; Alan Nicholas; Nicolas Sommer; Bendell
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Phase 1b study of venetoclax-obinutuzumab in previously untreated and relapsed/refractory chronic lymphocytic leukemia
Blood, ISSN: 15280020 00064971
Ian W. Flinn; John G. Gribben; Martin J S Dyer; William G. Wierda; Michael B. Maris; Richard Furman; Hillmen; Kerry A. Rogers; Swaminathan Padmanabhan Iyer; Anne Quillet-Mary; Loic Ysebaert; Harriet S. Walter; Maria Verdugo; Christian Klein; Huang Huang; Yanwen Jiang; Gerard Lozanski; Daniela Soriano Pignataro; Kathryn Humphrey; Mehrdad Mobasher; Thomas J. Kipps
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Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis
Cell Reports, ISSN: 22111247
Hsu; Sébastien Tabariès; Johnson; Sylvia Andrzejewski; Julien Senecal; Camille Lehuédé; Matthew G. Annis; Ma; Sandra Völs; LeeAnn Ramsay; Remi Froment; Anie Monast; Ian R. Watson; Zvi Granot; Jones; Julie St-Pierre; Siegel
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Green Chemistry Articles of Interest to the Pharmaceutical Industry
Organic Process Research and Development, ISSN: 1520586X 10836160
Marie-Gabrielle Braun; Alba Díaz-Rodríguez; Louis Diorazio; Zhongbo Fei; Kenneth Fraunhoffer; John Hayler; Matthew Hickey; Mark McLaws; Paul Richardson; Gheorghe-Doru Roiban; Andrew T. Parsons; Alan Steven; Jack A. Terrett; Timothy White; Jingjun Yin
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Mechanisms of immune-related adverse events associated with immune checkpoint blockade: Using germline genetics to develop a personalized approach
Genome Medicine, ISSN: 1756994X
Zia Khan; Christian Hammer; Ellie Guardino; G. Scott Chandler; Matthew L. Albert
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Atezolizumab plus bevacizumab versus sunitinib in patients with previously untreated metastatic renal cell carcinoma (IMmotion151): a multicentre, open-label, phase 3, randomised controlled trial
The Lancet, ISSN: 1474547X 01406736
Brian I Rini; Thomas Powles; Michael B. Atkins; Bernard Escudier; David McDermott; Cristina Suárez; Sergio Bracarda; Walter M. Stadler; Frede Donskov; Jae-Lyun Lee; Robert E. Hawkins; Alain Ravaud; Boris Alekseev; Michael D. Staehler; Motohide Uemura; Ugo De Giorgi; Begoña Mellado; Camillo Porta; Melichar; Howard Gurney; Jens Bedke; Toni K. Choueiri; Francis Parnis; Tarik Khaznadar; Alpa Thobhani; Shi Li; Elisabeth Piault-Louis; Gretchen D. Frantz; Mahrukh Huseni; Christina Schiff; Marjorie Green; Robert J. Motzer
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Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Mark Zak; Emily J. Hanan; Patrick J. Lupardus; David G. Brown; Colin Robinson; Michael Siu; Joseph P. Lyssikatos; F. Anthony Romero; Guiling Zhao; Terry Kellar; Rohan Mendonca; Nicholas C. Ray; Simon Goodacre; Peter H. Crackett; Neville J. McLean; Christopher A. Hurley; Po-Wai Yuen; Yun-Xing Cheng; Xiongcai Liu; Marya Liimatta; Pawan Bir Kohli; Jim Nonomiya; Gary Salmon; Gerry Buckley; Julia Lloyd; Paul Gibbons; Nico Ghilardi; Jane R. Kenny; Adam R. Johnson
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Potent and selective inhibitors of receptor-interacting protein kinase 1 that lack an aromatic back pocket group
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Gregory L. Hamilton; Huifen Chen; Gauri Deshmukh; Eigenbrot; Rina Fong; Adam R. Johnson; Pawan Bir Kohli; Patrick J. Lupardus; Bianca M. Liederer; Sreemathy Ramaswamy; Haowei Wang; Jian Wang; Zhaowu Xu; Yunliang Zhu; Domagoj Vucic; Snahel Patel
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Atezolizumab plus bevacizumab versus sunitinib in patients with previously untreated metastatic renal cell carcinoma (IMmotion151): a multicentre, open-label, phase 3, randomised controlled trial
The Lancet, ISSN: 1474547X 01406736
Brian I Rini; Thomas Powles; Michael B. Atkins; Bernard Escudier; David McDermott; Cristina Suárez; Sergio Bracarda; Walter M. Stadler; Frede Donskov; Jae-Lyun Lee; Robert Hawkins; Alain Ravaud; Boris Alekseev; Michael D. Staehler; Motohide Uemura; Ugo De Giorgi; Begoña Mellado; Camillo Porta; Melichar; Howard Gurney; Jens Bedke; Toni K. Choueiri; Francis Parnis; Tarik Khaznadar; Alpa Thobhani; Shi Li; Elisabeth Piault-Louis; Gretchen D. Frantz; Mahrukh Huseni; Christina Schiff; Marjorie Green; Robert J. Motzer
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PTCD1IS required for mitochondrial oxidative-phosphorylation: Possible genetic association with Alzheimer’s disease
Journal of Neuroscience, ISSN: 15292401 02706474
Daniel Fleck; Lilian Phu; Erik Verschueren; Trent Hinkle; Mike Reichelt; Tushar Bhangale; Benjamin Haley; Yuanyuan Wang; Robert R. Graham; Donald S. Kirkpatrick; Morgan Sheng; Baris Bingol
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Real-world treatment patterns and adverse events in metastatic renal cell carcinoma from a large US claims database
BMC Cancer, ISSN: 14712407
Sumanta Kumar Pal; Jun Gong; Shivani K. Mhatre; Shih Wen Lin; Andy Surinach; Sarika Ogale; Rini Vohra; Herschel Wallen; Daniel George
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Obinutuzumab plus chemotherapy followed by obinutuzumab monotherapy is cost-effective vs. rituximab plus chemotherapy followed by rituximab monotherapy for previously untreated follicular lymphoma patients in the United States
Leukemia and Lymphoma, ISSN: 10292403 10428194
Gregory F. Guzauskas; Anthony Masaquel; Per-Olof Thuresson; Keith Dawson; David L. Veenstra
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Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb
Analytical Chemistry, ISSN: 15206882 00032700
Jeffrey W. Hudgens; Elyssia S. Gallagher; Ioannis Karageorgos; Kyle W. Anderson; James J. Filliben; Richard Y.-C. Huang; Guodong Chen; George M. Bou-Assaf; Alfonso Espada; Michael J. Chalmers; Eduardo Harguindey; Hui-Min Zhang; Benjamin T. Walters; Jennifer Zhang; John Venable; Caitlin Steckler; Inhee Park; Ansgar Brock; Xiaojun Lu; Ratnesh Pandey; Arun Chandramohan; Ganesh Srinivasan Anand; Sasidhar N. Nirudodhi; Justin B. Sperry; Jason C. Rouse; James A. Carroll; Kasper D. Rand; Ulrike Leurs; David D. Weis; Mohammed A. Al-Naqshabandi; Tyler S. Hageman; Daniel Deredge; Patrick L. Wintrode; Malvina Papanastasiou; John D. Lambris; Sheng Li; Sarah Urata
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Regio- and Enantioselective Iridium-Catalyzed N-Allylation of Indoles and Related Azoles with Racemic Branched Alkyl-Substituted Allylic Acetates
Angewandte Chemie - International Edition, ISSN: 15213773 14337851
Seung Wook Kim; Tabitha T. Schempp; Jason R. Zbieg; Craig E. Stivala; Michael J. Krische
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Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux
European Respiratory Journal, ISSN: 13993003 09031936
Jeanne-Marie Perotin; James P.R. Schofield; Susan J. Wilson; Jonathan Ward; Joost Brandsma; Fabio Strazzeri; Aruna T. Bansal; Xian Yang; Anthony Rowe; Julie Corfield; Rene Lutter; Dominic E Shaw; Per Bakke; Massimo Caruso; Barbro Dahlén; Stephen J. Fowler; Ildikó Horváth; Peter H. Howarth; Norbert Krug; Paolo Montuschi; Marek Sanak; Thomas Sandström; Kai Sun; Ioannis Pandis; Charles Auffray; Bertrand De Meulder; Diane Lefaudeux Ana R. Sousa; Sven-Erik Dahlen; Ian M. Adcock; Kian Fan Chung; Peter J. Sterk; Paul J. Skipp; John Riley; Jane E. Collins; Donna E. Davies; Ratko Djukanovic; Hassan Ahmed; Banssal; Frédéric Baribaud; Stewart Bates; Elisabeth H. Bel; Jeannette Bigler; Hans Bisgaard; Michael J. Boedigheimer; Klaus Bønnelykke; Paul Brinkman; Enrica Bucchioni; Dominic Burg; Bush; Amphun Chaiboonchoe; Chanez; Chris H. Compton; Arnaldo D'Amico; Veit J. Erpenbeck; Damijan Erzen; Klaus Fichtner; Neil Fitch; Louise J. Fleming; Formaggio; Frey; Martina Gahlemann; Thomas Geiser; Guo; Simone Hashimoto; John Haughney; Gunilla Hedlin; Pieter-Paul Hekking; Tim Higenbottam; Hohlfeld; Cecile Holweg; James; Richard Knowles; Alan J. Knox; Diane Lefaudeux; Matthew J. Loza; Sarah Masefield; John Matthews; Mazein; Andrea Meiser; Roelinde Middelveld; Montse Miralpeix; Nadia Mores; Clare S. Murray; Jacek Musial; David Myles; Laurie Pahus; Stelios Pavlidis; Pippa Powell; Praticò; M. Puig Valls; Navin Rao; Amanda Roberts; Graham Roberts; Wolfgang Seibold; Selby; Ralf Sigmund; Florian Singer; Bob Thornton; Wim van Aalderen; van Geest; Jorgen Vestbo; Nadja Vissing; Ariane H. Wagener; Scott Wagers; Zsoka Weiszhart; Craig E. Wheelock; Antonios O. Aliprantis; David Allen; Alving; Philipp Badorrek; David Balgoma; Stéphane Ballereau; Clair Barber; Manohara Batuwitage; An Bautmans; Alun Bedding; Annelie F. Behndig; Jorge Beleta; Ann Berglind; Alix Berton; Grazyna Bochenek; Armin Braun; Davide Campagna; Leon Carayannopoulos; Casaulta; Romanas Chaleckis; Timothy Davison; Jorge De Alba; Inge De Lepeleire; Tamara Dekker; Ingrid Delin; Patrick Dennison; Annemiek Dijkhuis; Paul Dodson; Aleksandra Draper; Kerry Dyson; Jessica Edwards; El Hadjam; Ray Emma; Magnus Ericsson; Cornelia Faulenbach; Breda Flood; Gabriella Galffy; Hactor Gallart; Garissi; Julaiha Gent; Maria Gerhardsson De Verdier; David Gibeon; Cristina Gomez; Kerry Gove; Neil Gozzard; Guillmant-Farry; Elisabeth Henriksson; Lorraine Hewitt; Uruj Hoda; Richard Hu; Sile Hu; Xugang Hu; Elizabeth Jeyasingham; Johnson; Jullian; Juliette Kamphuis; Erika J. Kennington; Dyson Kerry; Gove Kerry; Matthias Klüglich; Hugo Knobel; Johan Kolmert; Jon Konradsen; Maxim Kots; Kosmas Kretsos; Linn Krueger; Scott Kuo; Maciej Kupczyk; Bart N. Lambrecht; Ann-Sofie Lantz; Christopher Larminie; Lars X. Larsson; Latzin; Nikos Lazarinis; Nathanaël Lemonnier; Saeeda Lone-Latif; Lowe; Alexander Manta; Lisa Marouzet; Martin; Caroline Mathon; McEvoy; Sally Meah; Andrew Menzies-Gow; Leanne Metcalf; Maria Mikus; Philip Monk; Shama Naz; Katja Nething; Ben Nicholas; Ulf Nihlen; Peter Nilsson; Robert Niven; Björn Nordlund; Nsubuga; Jörgen östling; Antonio Pacino; Susanna Palkonen; Johann Pellet; Giorgio Pennazza; Anne Petrén; Sandy Pink; Pison; Anthony Postle; Malayka Rahman-Amin; Lara Ravanetti; Emma Ray; Reinke Stacey; Leanne Reynolds; Kathrin Riemann; Martine Robberechts; Rocha; Christos Rossios; Russell; Michael Rutgers; Giuseppe Santini; Marco Santoninco; Mansoor Saqi; Corinna Schoelch; Scott; Sehgal; Marcus Sjödin; Barbara Smids; Caroline Smith; Jessica Smith; Katherine Smith; Päivi Söderman; Sogbessan; Spycher; Doroteya Staykova; Stephan; Stokholm; Karin Strandberg; Sunther; Szentkereszty Marton; Lilla Tamasi; Kamran Tariq; John-Olof Thörngren; Jonathan Thorsen; Salvatore Valente; Marianne van de Pol; Cornelis M. Van Drunen; Jonathan van Eyll; Jenny Versnel; Anton Vink; Christophe Von Garnier; Vyas; Frans Wald; Samantha Walker; Kristiane Wetzel; Coen Wiegman; Siân Williams; Elizabeth Yeyasingham; Wen Yu; Wilhelm Zetterquist; Zolkipli; Aeilko H. Zwinderman; Prins; Visintin; Evans; Puhl; Buzermaniene; Val Hudson; Bond; de Boer; Widdershoven; David Supple; Dominique Hamerlijnck; Negus; Sergison; Onstein; MacNee; Bernardini; Louis Bont; Wecksell
View on Scopus
Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux
European Respiratory Journal, ISSN: 13993003 09031936
Jeanne-Marie Perotin; James P.R. Schofield; Susan J. Wilson; Jonathan Ward; Joost Brandsma; Fabio Strazzeri; Aruna T. Bansal; Xian Yang; Anthony Rowe; Julie Corfield; Rene Lutter; Dominick E. Shaw; Per Bakke; Massimo Caruso; Barbro Dahlén; Stephen J. Fowler; Ildikó Horváth; Peter H. Howarth; Norbert Krug; Paolo Montuschi; Marek Sanak; Thomas Sandström; Kai Sun; Ioannis Pandis; Charles Auffray; Bertrand De Meulder; Diane Lefaudeux Ana R. Sousa; Sven-Erik Dahlen; Ian M. Adcock; Kian Fan Chung; Peter J. Sterk; Paul J. Skipp; John Riley; Jane E. Collins; Donna E. Davies; Ratko Djukanovic; Hassan Ahmed; Banssal; Frédéric Baribaud; Stewart Bates; Elisabeth H. Bel; Jeannette Bigler; Hans Bisgaard; Michael J. Boedigheimer; Klaus Bønnelykke; Paul Brinkman; Enrica Bucchioni; Dominic Burg; Bush; Amphun Chaiboonchoe; Chanez; Chris H. Compton; Arnaldo D'Amico; Veit J. Erpenbeck; Damijan Erzen; Klaus Fichtner; Neil Fitch; Louise J. Fleming; Formaggio; Frey; Martina Gahlemann; Thomas Geiser; Guo; Hashimoto; John Haughney; Gunilla Hedlin; Pieter-Paul Hekking; Tim Higenbottam; Hohlfeld; Cecile Holweg; James; Richard Knowles; Alan J. Knox; Diane Lefaudeux; Matthew J. Loza; Sarah Masefield; Matthews; Mazein; Andrea Meiser; Roelinde Middelveld; Montse Miralpeix; Nadia Mores; Clare S. Murray; Jacek Musial; David Myles; Laurie Pahus; Stelios Pavlidis; Pippa Powell; Praticò; M. Puig Valls; Rao; Amanda Roberts; Graham Roberts; Wolfgang Seibold; Selby; Ralf Sigmund; Florian Singer; Bob Thornton; Wim van Aalderen; van Geest; Jorgen Vestbo; Nadja Vissing; Ariane H. Wagener; Scott Wagers; Zsoka Weiszhart; Craig E. Wheelock; Antonios O. Aliprantis; David Allen; Alving; Philipp Badorrek; David Balgoma; Stéphane Ballereau; Clair Barber; Manohara Batuwitage; An Bautmans; Alun Bedding; Annelie F. Behndig; Jorge Beleta; Ann Berglind; Alix Berton; Grazyna Bochenek; Armin Braun; Davide Campagna; Leon Carayannopoulos; Casaulta; Romanas Chaleckis; Timothy Davison; Jorge De Alba; Inge De Lepeleire; Tamara Dekker; Ingrid Delin; Patrick Dennison; Annemiek Dijkhuis; Paul Dodson; Aleksandra Draper; Kerry Dyson; Jessica Edwards; El Hadjam; Ray Emma; Magnus Ericsson; Cornelia Faulenbach; Breda Flood; Gabriella Galffy; Hactor Gallart; Garissi; Julaiha Gent; Maria Gerhardsson De Verdier; David Gibeon; Cristina Gomez; Kerry Gove; Neil Gozzard; Guillmant-Farry; Elisabeth Henriksson; Lorraine Hewitt; Uruj Hoda; Richard Hu; Sile Hu; Xugang Hu; Elizabeth Jeyasingham; Johnson; Jullian; Juliette Kamphuis; Erika J. Kennington; Dyson Kerry; Gove Kerry; Matthias Klüglich; Hugo Knobel; Johan Kolmert; Jon Konradsen; Maxim Kots; Kosmas Kretsos; Linn Krueger; Kuo; Maciej Kupczyk; Bart N. Lambrecht; Ann-Sofie Lantz; Christopher Larminie; Lars X. Larsson; Latzin; Nikos Lazarinis; Nathanaël Lemonnier; Saeeda Lone-Latif; Lowe; Alexander Manta; Lisa Marouzet; Martin; Caroline Mathon; McEvoy; Sally Meah; Andrew Menzies-Gow; Leanne Metcalf; Maria Mikus; Philip Monk; Shama Naz; Katja Nething; Ben Nicholas; Ulf Nihlen; Peter Nilsson; Robert Niven; Björn Nordlund; Nsubuga; Jörgen östling; Antonio Pacino; Susanna Palkonen; Johann Pellet; Giorgio Pennazza; Anne Petrén; Sandy Pink; Pison; Anthony Postle; Malayka Rahman-Amin; Lara Ravanetti; Emma Ray; Reinke Stacey; Leanne Reynolds; Kathrin Riemann; Martine Robberechts; Rocha; Christos Rossios; Russell; Michael Rutgers; Giuseppe Santini; Marco Santoninco; Mansoor Saqi; Corinna Schoelch; Scott; Sehgal; Marcus Sjödin; Barbara Smids; Caroline Smith; Jessica Smith; Katherine Smith; Päivi Söderman; Sogbessan; Spycher; Doroteya Staykova; Stephan; Stokholm; Karin Strandberg; Sunther; Szentkereszty Marton; Lilla Tamasi; Kamran Tariq; John-Olof Thörngren; Jonathan Thorsen; Salvatore Valente; Marianne van de Pol; Cornelis M. Van Drunen; Jonathan van Eyll; Jenny Versnel; Anton Vink; Christophe Von Garnier; Vyas; Frans Wald; Samantha Walker; Kristiane Wetzel; Coen Wiegman; Siân Williams; Elizabeth Yeyasingham; Wen Yu; Wilhelm Zetterquist; Zolkipli; Aeilko H. Zwinderman; Prins; Visintin; Evans; Puhl; Buzermaniene; Val Hudson; Bond; de Boer; Widdershoven; David Supple; Dominique Hamerlijnck; Negus; Sergison; Onstein; MacNee; Bernardini; Louis Bont; Wecksell
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Predicting Human Infection Risk: Do Rodent Host Resistance Models Add Value?
Toxicological Sciences, ISSN: 10960929 10966080
Kai Connie Wu; Yu Zhong; Jonathan M. Maher
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A Flexible Approach for Context-Dependent Assessment of Quantitative Systems Pharmacology Models
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Ramanujan; Jason R. Chan; Christina M. Friedrich; Craig J. Thalhauser
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Convergent genetic aberrations in murine and human t lineage acute lymphoblastic leukemias
PLoS Genetics, ISSN: 15537404 15537390
Benjamin J. Huang; Anica M. Wandler; Lauren K. Meyer; Monique Dail; Anneleen Daemen; Deepak Sampath; Qing Li; Xinyue Wang; Jasmine C. Y. Wong; Joy Nakitandwe; James R. Downing; Jinghui Zhang; Barry S. Taylor; Kevin Shannon
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Massive antibody discovery used to probe structure–function relationships of the essential outer membrane protein lptd
eLife, ISSN: 2050084X
Kelly M. Storek; Joyce Chan; Rajesh Vij; Nancy Y. Chiang; Zhonghua Lin; Jack Bevers; Christopher M. Koth; Jean-Michel Vernes; Y. Gloria Meng; Jianping Yin; Heidi J. A. Wallweber; Olivier Dalmas; Stephanie K. Shriver; Christine Tam; Kellen Schneider; Dhaya Seshasayee; Nakamura; Peter A. Smith; Jian Payandeh; James T. Koerber; Laetitia Comps-Agrar; Steven T. Rutherford
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Coexpression of inhibitory receptors enriches for activated and functional CD8+ T cells in murine syngeneic tumor models
Cancer immunology research, ISSN: 23266074 23266066
Huizhong Xiong; Stephanie Mittman; Ryan Rodriguez; Patricia Pacheco-Sanchez; Marina Moskalenko; Yagai Yang; Justin Elstrott; Alex T. Ritter; Sören Müller; Dorothee Nickles; Teresita L. Arenzana; Aude-Hélène Capietto; Lélia Delamarre; Zora Modrusan; Sascha Rutz; Ira Mellman; Rafael Cubas
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In vivo assessment of antibody-dependent enhancement of influenza B infection
Toxicological Sciences, ISSN: 10960929 10966080
Gautham K. Rao; Prell; Steven T. Laing; Stefanie C M Burleson; Allen Nguyen; Jacqueline McBride; Crystal Zhang; Daniel Sheinson; Wendy Halpern
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Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients
Nature Medicine, ISSN: 1546170X 10788956
Ryan J. Sullivan; Omid Hamid; Rene Gonzalez; Jeffery R. Infante; Manish R. Patel; F. Stephen Hodi; Karl Lewis; Hussein Tawbi; Genevive Hernandez; Matthew Wongchenko; YiMeng Chang; Louise Roberts; Ballinger; Yibing Yan; Edward Cha; Patrick Hwu
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Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients
Nature Medicine, ISSN: 1546170X 10788956
Ryan J. Sullivan; Omid Hamid; Rene Gonzalez; Jeffery R. Infante; Manish R. Patel; F. Stephen Hodi; Karl Lewis; Hussein Tawbi; Genevive Hernandez; Matthew Wongchenko; YiMeng Chang; Louise Roberts; Ballinger; Yibing Yan; Edward Cha; Patrick Hwu
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Effects of concomitant glucocorticoids in TOZURA, a common-framework study programme of subcutaneous tocilizumab in rheumatoid arthritis
Rheumatology, ISSN: 14620332 14620324
Ernest Choy; Roberto Caporali; Ricardo Xavier; Bruno Fautrel; Raimón Sanmarti; Bao; Jenny Devenport; Attila Pethö-Schramm
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Genomic features of exceptional response in vemurafenib cobimetinib–treated patients with BRAFV600-mutated metastatic melanoma
Clinical Cancer Research, ISSN: 15573265 10780432
Yibing Yan; Matthew Wongchenko; Caroline Robert; James Larkin; Paolo A. Ascierto; Brigitte Dréno; Michele Maio; Claus Garbe; Paul B. Chapman; Jeffrey A. Sosman; Zhen Shi; Koeppen; Jessie Hsu; Ilsung Chang; Ivor Caro; Isabelle Rooney; McArthur; Antoni Ribas
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Phase I study of the indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor navoximod (GDC-0919) administered with PD-L1 inhibitor (atezolizumab) in advanced solid tumors
Clinical Cancer Research, ISSN: 15573265 10780432
Kyung Hae Jung; Patricia M. LoRusso; Howard A. Burris; Michael S. Gordon; Bang; Matthew D. Hellmann; Andrés Cervantes; Maria Ochoa de Olza; Aurélien Marabelle; F. Stephen Hodi; Myung-Ju Ahn; Leisha A. Emens; Fabrice Barlesi; Omid Hamid; Calvo; David McDermott; Hatem Soliman; Ina Rhee; Ray Lin; Tony Pourmohamad; Julia Suchomel; Amy Tsuhako; Kari M. Morrissey; Sami Mahrus; Roland Morley; Andrea Pirzkall; S. Lindsey Davis
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A phase 1, randomized, single-ascending-dose study to investigate the safety, tolerability, and pharmacokinetics of DSTA4637S, an anti-staphylococcus aureus thiomab antibody-antibiotic conjugate, in healthy volunteers
Antimicrobial Agents and Chemotherapy, ISSN: 10986596 00664804
Melicent Peck; Michael E. Rothenberg; Rong Deng; Nicholas Lewin-Koh; Gaohong She; Amrita Kamath; Montserrat Carrasco-Triguero; Ola M. Saad; Aide Castro; Lisa Teufel; Daniel S. Dickerson; Marisa Leonardelli; Jorge A. Tavel
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Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial
The Lancet Oncology, ISSN: 14745488 14702045
Cathy Eng; Kim; Bendell; Guillem Argiles; Niall C. Tebbutt; Maria Di Bartolomeo; Alfredo Falcone; Marwan Fakih; Alberto Sobrero; Yibing Yan; Ilsung Chang; Anne Uyei; Louise Roberts; Fortunato Ciardiello; Ahn; Jamil Asselah; Badarinath; Baijal; Begbie; Berry; Jean-Luc Canon; Carbone; Andrés Cervantes; Cha; Chang; Chaudhry; Chmielowska; Cho; Chu; Couture; Jennifer Cultrera; David Cunningham; Eric Van Cutsem; Cuyle; Davies; Dowden; Dvorkin; Vinod Ganju; Garcia; Kerr; Kim; King; Kortmansky; Kozloff; Lam; Lee; Lee; Lesperance; Luppi; Ma; Evaristo Maiello; Mandanas; John Marshall; Marx; Mullamitha; Nechaeva; Park; Pavlakis; Ponce; Potemski; Sherif Raouf; James A. Reeves; Neil H. Segal; Siena; Smolin; Streb; Strickland; Szutowicz-Zielinska; Tabernero; Tan; Valera; Van den Eynde; Vergauwe; Vickers; Womack; Wroblewska; Young
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Efficacy, safety, and pharmacokinetics of emicizumab prophylaxis given every 4 weeks in people with haemophilia A (HAVEN 4): a multicentre, open-label, non-randomised phase 3 study
The Lancet Haematology, ISSN: 23523026
Steven W Pipe; Midori Shima; Michaela Lehle; Amy Shapiro; Sammy Chebon; Katsuyuki Fukutake; Nigel S. Key; Agnès Portron; Christophe Schmitt; Maria Podolak-Dawidziak; Nives Selak Bienz; Cedric Hermans; Avrita Campinha-Bacote; Anna Kiialainen; Kathelijne Peerlinck; Gallia Levy; Jiménez-Yuste
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Pharmacokinetic and exploratory exposure–response analysis of pertuzumab in patients with operable HER2-positive early breast cancer in the APHINITY study
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Whitney P. Kirschbrown; Kagedal; Wang; Lars Lindbom; Adam Knott; Rachelle Mack; Sharareh Monemi; Ihsan Nijem; Sandhya Girish; Christie Freeman; Fumagalli; Robin McConnell; Guy Jerusalem; Chris Twelves; José Baselga; Gunter Von Minckwitz; José Bines; Amit Garg
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Concerns Regarding Phase 1b Clinical Trial of Atezolizumab Plus Nab-Paclitaxel for Metastatic Breast Cancer - In Reply
JAMA Oncology, ISSN: 23742445 23742437
Sylvia Adams; Luciana L. Molinero
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Influence of genetic copy number variants of the human GLUT3 glucose transporter gene SLC2A3 on protein expression, glycolysis and rheumatoid arthritis risk: A genetic replication study
Molecular Genetics and Metabolism Reports, ISSN: 22144269
Kim R. Simpfendorfer; Wentian Li; Andrew Shih; Hongxiu Wen; Harini P. Kothari; Edward A. Einsidler; Arthur Wuster; Julie Hunkapiller; Timothy W. Behrens; Robert R. Graham; Michael J. Townsend; Doron M. Behar; Rui Hu; Elliott Greenspan; Peter K. Gregersen
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Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients
Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
Frances Humby; Myles J. Lewis; Nandhini Ramamoorthi; Jason A. Hackney; Michael R. Barnes; Michele Bombardieri; A F. Setiadi; Stephen Kelly; Fabiola Bene; Maria Dicicco; Sudeh Riahi; Vidalba Rocher; Nora Ng; Ilias Lazarou; Rebecca Hands; Desirée Van Der Heijde; Robert Landewé; Annette H. M. Van Der Helm-van Mil; Alberto Cauli; McInnes; Christopher D. Buckley; Ernest Choy; Taylor; Michael J. Townsend; Costantino Pitzalis
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