Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

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October 1, 2018

Using pH Gradient Dissolution with In-Situ Flux Measurement to Evaluate Bioavailability and DDI for Formulated Poorly Soluble Drug Products

AAPS PharmSciTech, ISSN: 15309932

Jane Li; Konstantin Tsinman; Oksana Tsinman; Larry Wigman

October 1, 2018

Humoral immunity goes hormonal: Studies of mice demonstrate a link between the female hormone estrogen and protection against bacteremia and sepsis through the induction of natural antibodies to eshcerichia coli

Nature Immunology, ISSN: 15292916 15292908

Joseph Chavarria-Smith; Wouter L. W. Hazenbos; Menno van Lookeren Campagne

October 1, 2018

Anatomy and physiology of the digestive tract of drosophila melanogaster

Genetics, ISSN: 19432631 00166731

Irene Miguel-Aliaga; Heinrich Jasper; Bruno Lemaitre

October 1, 2018

Serum periostin as a biomarker in eosinophilic granulomatosis with polyangiitis

PLoS ONE, ISSN: 19326203

Rennie L. Rhee; Cecile Holweg; Kit Wong; David Cuthbertson; Simon Carette; Nader A. Khalidi; Curry L. Koening; Langford; Carol A. McAlear; Paul A. Monach; Larry W. Moreland; Christian Pagnoux; Seo; Specks; Antoine G. Sreih; Steven R. Ytterberg; Peter A. Merkel

October 1, 2018

Pertuzumab plus trastuzumab and chemotherapy for HER2-positive metastatic gastric or gastro-oesophageal junction cancer (JACOB): final analysis of a double-blind, randomised, placebo-controlled phase 3 study

The Lancet Oncology, ISSN: 14745488 14702045

Tabernero; Paulo M. Hoff; Lin Shen; Atsushi Ohtsu; Manish A. Shah; Karen Cheng; Chunyan Song; Haiyan Wu; Jennifer Eng-Wong; Katherine Kim; Yoon-Koo Kang

October 1, 2018

Evaluation of no evidence of progression or active disease (NEPAD) in patients with primary progressive multiple sclerosis in the ORATORIO trial

Annals of Neurology, ISSN: 15318249 03645134

Wolinsky; Montalban; Stephen L. Hauser; Giovannoni; Patrick Vermersch; Corrado Bernasconi; Gurpreet Deol-Bhullar; Hideki Garren; Peter Chin; Belachew; Ludwig Kappos

October 1, 2018

Humoral immunity goes hormonal: Studies of mice demonstrate a link between the female hormone estrogen and protection against bacteremia and sepsis through the induction of natural antibodies to eshcerichia coli

Nature Immunology, ISSN: 15292916 15292908

Joseph Chavarria-Smith; Wouter L. W. Hazenbos; Menno van Lookeren Campagne

October 1, 2018

Ranibizumab Induces Regression of Diabetic Retinopathy in Most Patients at High Risk of Progression to Proliferative Diabetic Retinopathy

Kidney International Reports, ISSN: 24686530

Charles C. Wykoff; David Eichenbaum; Daniel B. Roth; Lauren Hill; Anne E. Fung; Zdenka Haskova

October 1, 2018

Identification of biological axes associated with stage II/III CRC recurrence risk and outcome after adjuvant therapy revealed a T-effector-independent prognostic role for granzyme B

Annals of Oncology, ISSN: 15698041

Meghna Das Thakur; Akshata R. Udyavar; Thomas Sandmann; Li; Bosch; William E. O'Gorman; Li; Amelia Au-Yeung; Chikara Takahashi; Richard Bourgon; Daemen; Priti Hegde; Carlos Bais

October 1, 2018

Molecular correlates differentiate response to atezolizumab (atezo) + bevacizumab (bev) vs sunitinib (sun): Results from a phase III study (IMmotion151) in untreated metastatic renal cell carcinoma (mRCC)

Annals of Oncology, ISSN: 15698041

Brian I Rini; Mahrukh Huseni; Michael B. Atkins; David McDermott; Thomas Powles; Bernard Escudier; Romain Banchereau; L-F Liu; Ning Leng; Fan; Doss; Sam C. Nalle; Carroll; Li; Christina Schiff; Marjorie Green; Robert J. Motzer

October 1, 2018

Clinical and analytical validation of an FDA approved comprehensive genomic profiling (CGP) assay incorporating multiple companion diagnostics for targeted and immunotherapies

Annals of Oncology, ISSN: 15698041

Li; James X. Sun; Skoletsky; Milbury; Burns; W-K Yip; Dewal; He; Tuesdell; Peters; Erica Schleifman; Johannes Noé; Jenkins; Elvin; Geoff A. Otto; Doron Lipson; Jeffrey S. Ross; Vincent A. Miller; Doherty; Vietz

October 1, 2018

Dissecting gastric cancer biology and how and when to use immunotherapy

Annals of Oncology, ISSN: 15698041

Meghna Das Thakur; Kwame Okrah; David S. Shames; Priti Hegde; Carlos Bais

October 1, 2018

Safety and tolerability of atezolizumab (atezo) plus bevacizumab (bev) vs sunitinib (sun) in untreated metastatic renal cell carcinoma (mRCC): Pooled analysis of IMmotion150 and IMmotion151

Annals of Oncology, ISSN: 15698041

Cristina Suárez; Toni K. Choueiri; David McDermott; Bernard Escudier; Michael B. Atkins; Thomas Powles; Brian I Rini; Robert J. Motzer; Sumanta Kumar Pal; Lawrence Fong; De Giorgi; Wang; Tarik Khaznadar; Di Nucci; Constanze Kaiser; Darren Tayama; Frede Donskov

October 1, 2018

IMpassion130: Results from a global, randomised, double-blind, phase III study of atezolizumab (atezo) + nab-paclitaxel (nab-P) vs placebo + nab-P in treatment-naive, locally advanced or metastatic triple-negative breast cancer (mTNBC)

Annals of Oncology, ISSN: 15698041

Schmid; Sylvia Adams; Hope S. Rugo; Andreas Schneeweiss; Carlos H. Barrios; Iwata; Diéras; Roberto Hegg; Seock-Ah Im; Wright; Henschel; Luciana L. Molinero; Chui; Roel Funke; Amreen Husain; Eric P. Winer; Loi; Leisha A. Emens

October 1, 2018

IMpower130: Progression-free survival (PFS) and safety analysis from a randomised phase III study of carboplatin + nab-paclitaxel (CnP) with or without atezolizumab (atezo) as first-line (1L) therapy in advanced non-squamous NSCLC

Annals of Oncology, ISSN: 15698041

Federico Cappuzzo; Michael McCleod; Maen Hussein; Alessandro Morabito; Achim Rittmeyer; Henry J Conter; Hans-Georg Kopp; Davey B Daniel; Steven McCune; Tarek Mekhail; Alona Zer; Niels Reinmuth; Ahad Sadiq; Venice Archer; Tania Ochi Lohmann; Lijia Wang; Marcin Kowanetz; Wei Lin; Alan Sandler; Howard West

October 1, 2018

MORPHEUS: A phase Ib/II umbrella study platform evaluating the safety and efficacy of multiple cancer immunotherapy (CIT)-based combinations in different tumour types

Annals of Oncology, ISSN: 15698041

Chau; Haag; Rahma; Teresa Macarulla; Steven McCune; Denise A. Yardley; Benjamin Solomon; Melissa L. Johnson; Vidal; Schmid; Guillem Argiles; Dimick; Sami Mahrus; Abdullah; He; Sayyed; Barak; Bleul; Edward Cha; Alexandra Drakaki

October 1, 2018

Biological features and clinical outcomes in atezolizumab (atezo)-treated patients (pts) with metastatic urothelial cancer (mUC) of the upper vs lower urinary tract (UTUC vs LTUC)

Annals of Oncology, ISSN: 15698041

Matthew D. Galsky; Romain Banchereau; Edward E. Kadel III; Teresa Ramirez-Montagut; Sanjeev Mariathasan; AnnChristine Thåström; Jonathan E. Rosenberg; Thomas Powles; Michiel S Van Der Heijden; Andrea Necchi

October 1, 2018

Primary efficacy results from B-F1RST, a prospective phase II trial evaluating blood-based tumour mutational burden (bTMB) as a predictive biomarker for atezolizumab (atezo) in 1L non-small cell lung cancer (NSCLC)

Annals of Oncology, ISSN: 15698041

Edward S. Kim; Velcheti; Tarek Mekhail; Leal; Dowell; Tsai; Dakhil; Stella; Shen; Hu; Sarah M. Paul; David S. Shames; Erica Schleifman; David Fabrizio; Yun; Phan; Mark A. Socinski

October 1, 2018

Long-term safety of pirfenidone: Results of the prospective, observational PASSPORT study

ERJ Open Research, ISSN: 23120541

Vincent Cottin; Dirk Koschel; Andreas Günther; Carlo Albera; Arata Azuma; C Magnus Sköld; Sara Tomassetti; Philip Hormel; John L. Stauffer; Indiana Strombom; Klaus-Uwe Kirchgaessler; Toby M. Maher

October 1, 2018

Predictive markers of anti-VEGF and emerging role of angiogenesis inhibitors as immunotherapeutics

Seminars in Cancer Biology, ISSN: 10963650 1044579X

Priti Hegde; Jeffery J. Wallin; Christoph Mancao

October 1, 2018

Efficacy of Ranibizumab in Eyes with Diabetic Macular Edema and Macular Nonperfusion in RIDE and RISE

Ophthalmology, ISSN: 15494713 01616420

Rahul K. Reddy; Dante Joseph Pieramici; Shamika Gune; Avanti Ghanekar; Na Lu; Carlos Quezada-Ruiz; Caroline R. Baumal

October 1, 2018

High Intracellular Seed Train BiP Levels Correlate With Poor Production Culture Performance in CHO Cells

Biotechnology Journal, ISSN: 18607314 18606768

Meg Tung; Danming Tang; Szu-Han Wang; Dejin Zhan; Karen Kiplinger; Shu Pan; Yifeng Jing; Amy Shen; Patrick Ahyow; Snedecor; Martin Gawlitzek; Shahram Misaghi

October 1, 2018

Applying a weight of evidence approach to the evaluation of developmental toxicity of biopharmaceuticals

Regulatory Toxicology and Pharmacology, ISSN: 10960295 02732300

Meredith Rocca; LaRonda L. Morford; Diann Blanset; Wendy Halpern; Joy A. Cavagnaro; Christopher J. Bowman

September 27, 2018

Dual Leucine Zipper Kinase Inhibitors for the Treatment of Neurodegeneration

Journal of Medicinal Chemistry, ISSN: 15204804 00222623

Michael Siu; Arundhati Sengupta Ghosh; Joe Lewcock

September 24, 2018

A phase Ib study to assess the efficacy and safety of vismodegib in combination with ruxolitinib in patients with intermediate- or high-risk myelofibrosis 11 Medical and Health Sciences 1103 Clinical Sciences 11 Medical and Health Sciences 1102 Cardiorespiratory Medicine and Haematology

Journal of Hematology and Oncology, ISSN: 17568722

Stephen Couban; Giulia Benevolo; William Donnellan; Jennifer Cultrera; Steffen Koschmieder; Srdan Verstovsek; Gregory Hooper; Christian Hertig; Tandon; Natalie Dimier; Vikram Malhi; Francesco Passamonti

September 19, 2018

Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mild-to-moderate Alzheimer's disease (BLAZE)

Alzheimer's Research and Therapy, ISSN: 17589193

Stephen Salloway; Lee Honigberg; William Cho; Michael Ward; Michel Friesenhahn; Flavia Brunstein; Angelica Quartino; David Clayton; Deborah L. Mortensen; Tobias Bittner; Carole Ho; Christina Rabe; Stephen P. Schauer; Kristin R. Wildsmith; Reina N. Fuji; Shehnaaz Suliman; Eric M. Reiman; Kewei Chen; Robert Paul

September 18, 2018

Subtle Changes in the Levels of BCL-2 Proteins Cause Severe Craniofacial Abnormalities

Cell Reports, ISSN: 22111247

Stephanie Grabow; Andrew J. Kueh; Francine Ke; Hannah K. Vanyai; Bilal N. Sheikh; Michael A. Dengler; William Chiang; Samantha Eccles; Ian M. Smyth; Lynelle K. Jones; Frederic J. De Sauvage; Mark Scott; Lachlan Whitehead; Voss; Andreas Strasser

September 18, 2018

Selective NaV1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain

Cell Reports, ISSN: 22111247

Girish Bankar; Samuel J. Goodchild; Sarah Howard; Karen Nelkenbrecher; Matthew Waldbrook; Michelle Dourado; Noah Shuart; Sophia Lin; Clint Young; Zhiwei Xie; Kuldip Khakh; Elaine Chang; Luis E. Sojo; Andrea Lindgren; Sultan Chowdhury; Shannon M. Decker; Michael Grimwood; Jean-Christophe Andrez; Christoph Dehnhardt; Jodie Pang; Jae H. Chang; Brian S. Safina; Daniel P. Sutherlin; Johnson; David Hackos; C. Lee Robinette; Charles J. Cohen

September 15, 2018

Tumor elastography and its association with collagen and the tumor microenvironment

Clinical Cancer Research, ISSN: 15573265 10780432

Johannes Riegler; Yassin Labyed; Stephen Rosenzweig; Vincent Javinal; Alessandra Castiglioni; Claudia X. Dominguez; Jason E. Long; Qingling Li; Wendy N. Sandoval; Melissa Junttila; Shannon J. Turley; Jill Schartner; Richard A. D. Carano

September 15, 2018

Phase II study of Taselisib (GDC-0032) in combination with fulvestrant in patients with HER2-negative, hormone receptor–positive advanced breast cancer

Clinical Cancer Research, ISSN: 15573265 10780432

Maura N. Dickler; Saura; Donald A. Richards; Ian E. Krop; Andrés Cervantes; Philippe L. Bedard; Manish R. Patel; Pusztai; Oliveira; Alison Cardenas; Na Cui; Wilson; Thomas J. Stout; Michael C. Wei; Jerry Y. Hsu; Baselga

September 13, 2018

Optimized arylomycins are a new class of Gram-negative antibiotics

Nature, ISSN: 14764687 00280836

Peter A. Smith; Michael F. T. Koehler; Hany S. Girgis; Donghong Yan; Yongsheng Chen; Yuan Chen; James J. Crawford; Matthew Durk; Robert I. Higuchi; Jing Kang; Jeremy Murray; Prasuna Paraselli; Summer Park; Wilson Phung; John Quinn; Tucker C. Roberts; Lionel Rouge; Jacob B. Schwarz; Elizabeth Skippington; John Wai; Min Xu; Zhiyong Yu; Hua Zhang; Man-Wah Tan; Christopher E. Heise

September 11, 2018

The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors

Science Signaling, ISSN: 19379145 19450877

Thijs Hagenbeek; Webster; Noelyn Kljavin; Matthew T. Chang; Trang Pham; Ho-June Lee; Christiaan N. Klijn; Allen G. Cai; Klara Totpal; Buvana Ravishankar; Nai-Ying Yang; Da-Hye Lee; Kevin B. Walsh; Georgia Hatzivassiliou; Cecile C. de la Cruz; Stephen Gould; Xiumin Wu; Wyne P. Lee; Shuqun Yang; Zhixiang Zhang; Qingyang Gu; Qunsheng Ji; Erica L. Jackson; Dae-Sik Lim; Anwesha Dey

September 6, 2018

Noncovalent inhibition of C481S Bruton tyrosine kinase by GDC-0853: A new treatment strategy for ibrutinib-resistant CLL

Blood, ISSN: 15280020 00064971

Sean D. Reiff; Elizabeth M. Muhowski; Daphne Guinn; Amy Lehman; Catherine A. Fabian; Carolyn Cheney; Rose Mantel; Lisa Smith; Amy J. Johnson; Wendy B. Young; Adam R. Johnson; Lichuan Liu; John C. Byrd; Jennifer A. Woyach

September 5, 2018

A phase Ib study of pictilisib (GDC-0941) in combination with paclitaxel, with and without bevacizumab or trastuzumab, and with letrozole in advanced breast cancer

Breast Cancer Research, ISSN: 1465542X 14655411

Patrick Schöffski; Sara Cresta; Ingrid A. Mayer; Hans Wildiers; Silvia Damian; Steven Gendreau; Isabelle Rooney; Kari M. Morrissey; Jill M. Spoerke; Vivian W. Ng; Stina M. Singel; Eric P. Winer

September 5, 2018

Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus

Science Translational Medicine, ISSN: 19466242 19466234

Emmanuel Clave; Itauá Leston Araujo; Cécile Alanio; Jacob Bergstedt; Alejandra Urrutia; Silvia Lopez-Lastra; Yan Li; Bruno Charbit; Cameron R. MacPherson; Milena Hasan; Breno Luiz Melo-Lima; Corinne Douay; Noémie Saut; Marine Germain; David-Alexandre Trégouët; Pierre-Emmanuel Morange; Magnus Fontes; James P. Di Santo; Matthew L. Albert; Antoine Toubert; Laurent Abel; Andres Alcover; Hugues Aschard; Kalla Astrom; Philippe Bousso; Pierre Bruhns; Ana Cumano; Caroline Demangel; Ludovic Deriano; James Di Santo; Françoise Dromer; Darragh Duffy; Gérard Eberl; Jost Enninga; Jacques Fellay; Magnus Fontes; Antonio Freitas; Odile Gelpi; Ivo Gomperts-Boneca; Milena Hasan; Serge Hercberg; Olivier Lantz; Claude Leclerc; Hugo Mouquet; Etienne Patin; Sandra Pellegrini; Stanislas Pol; Antonio Rausell; Lars Rogge; Anavaj Sakuntabhai; Olivier Schwartz; Benno Schwikowski; Spencer Shorte; Vassili Soumelis; Frédéric Tangy; Eric Tartour; Antoine Toubert; Mathilde Touvier; Marie-Noëlle Ungeheuer; Lluis Quintana-Murci; Matthew L. Albert

September 5, 2018

Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus

Science Translational Medicine, ISSN: 19466242 19466234

Emmanuel Clave; Itauá Leston Araujo; Cécile Alanio; Jacob Bergstedt; Alejandra Urrutia; Silvia Lopez-Lastra; Yan Li; Bruno Charbit; Cameron R. MacPherson; Milena Hasan; Breno Luiz Melo-Lima; Corinne Douay; Noémie Saut; Marine Germain; David-Alexandre Trégouët; Pierre-Emmanuel Morange; Magnus Fontes; James P. Di Santo; Antoine Toubert; Laurent Abel; Andres Alcover; Hugues Aschard; Kalla Astrom; Philippe Bousso; Pierre Bruhns; Ana Cumano; Caroline Demangel; Ludovic Deriano; James Di Santo; Françoise Dromer; Darragh Duffy; Gérard Eberl; Jost Enninga; Jacques Fellay; Magnus Fontes; Antonio Freitas; Odile Gelpi; Ivo Gomperts-Boneca; Milena Hasan; Serge Hercberg; Olivier Lantz; Claude Leclerc; Hugo Mouquet; Etienne Patin; Sandra Pellegrini; Stanislas Pol; Antonio Rausell; Lars Rogge; Anavaj Sakuntabhai; Olivier Schwartz; Benno Schwikowski; Spencer Shorte; Vassili Soumelis; Frédéric Tangy; Eric Tartour; Antoine Toubert; Mathilde Touvier; Marie-Noëlle Ungeheuer; Lluis Quintana-Murci; Matthew L. Albert

September 4, 2018

Exploration of Pyrrolobenzodiazepine (PBD)-Dimers Containing Disulfide-Based Prodrugs as Payloads for Antibody-Drug Conjugates

Molecular Pharmaceutics, ISSN: 15438392 15438384

Zhonghua Pei; Chunjiao Chen; Jinhua Chen; Josefa Dela Cruz-Chuh; Reginald Delarosa; Yuzhong Deng; Aimee Fourie-O'Donohue; Isabel Figueroa; Jun Guo; Weiwei Jin; S. Cyrus Khojasteh; Katherine R. Kozak; Brandon Latifi; James Lee; Guangmin Li; Eva Lin; Liling Liu; Jiawei Lu; Scott E. Martin; Carl Ng; Trung Nguyen; Rachana Ohri; Gail L. Phillips; Thomas H. Pillow; Rebecca K. Rowntree; Nicola J. Stagg; David Stokoe; Sheila Ulufatu; Vishal A. Verma; John Wai; Jing Wang; Keyang Xu; Zijin Xu; Hui Yao; Shang-Fan Yu; Donglu Zhang; Peter Dragovich

September 4, 2018

Pan-Cancer Metabolic Signature Predicts Co-Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High-Mesenchymal Cell State

Cell Metabolism, ISSN: 19327420 15504131

Anneleen Daemen; Bonnie Liu; Kyung Song; Mandy Kwong; Min Gao; Rebecca Hong; Michelle Nannini; David Peterson; Bianca M. Liederer; Cecile C. de la Cruz; Dewakar Sangaraju; Allan Jaochico; Xiaofeng Zhao; Wendy N. Sandoval; Thomas Hunsaker; Ron Firestein; Sheerin Latham; Deepak Sampath; Marie Evangelista; Georgia Hatzivassiliou

September 2, 2018

MAPPs for the identification of immunogenic hotspots of biotherapeutics; an overview of the technology and its application to the biopharmaceutical arena

Expert Review of Proteomics, ISSN: 17448387 14789450

Quarmby; Qui Phung; Jennie R. Lill

September 1, 2018

Long-term survival follow-up of atezolizumab in combination with platinum-based doublet chemotherapy in patients with advanced non–small-cell lung cancer

European Journal of Cancer, ISSN: 18790852 09598049

Stephen V. Liu; D. Ross Camidge; Scott Gettinger; Giuseppe Giaccone; Rebecca S. Heist; F. Stephen Hodi; Neal E. Ready; Wei Zhang; Jeffery J. Wallin; Roel Funke; Waterkamp; Paul Foster; Koho Iizuka; John D. Powderly

September 1, 2018

Safety and clinical activity of atezolizumab monotherapy in metastatic non-small-cell lung cancer: final results from a phase I study

European Journal of Cancer, ISSN: 18790852 09598049

Leora Horn; Scott Gettinger; Michael S. Gordon; Roy S. Herbst; Leena Gandhi; Enriqueta Felip; Lecia V. Sequist; David Spigel; Scott J. Antonia; Ani Balmanoukian; Philippe A. Cassier; Bo Liu; Marcin Kowanetz; Carol E. O'Hear; Marcella Fassò; William Grossman; Alan Sandler; Jean-Charles Soria

September 1, 2018

Considerations from the innovation and quality induction working group in response to drug-drug interaction guidances from regulatory agencies: Focus on CYP3A4 mRNA in vitro response thresholds, variability, and clinical relevances

Drug Metabolism and Disposition, ISSN: 1521009X 00909556

Jane R. Kenny; Diane Ramsden; David Buckley; Shannon Dallas; Conrad Fung; Michael A. Mohutsky; Heidi J. Einolf; Liangfu Chen; Joshua G. DeKeyser; Maria Fitzgerald; Theunis C Goosen; Amy Siu; Robert L. Walsky; George Zhang; Donald J. Tweedie; Niresh Hariparsad

September 1, 2018

Analytical Validation of a Hybrid Capture–Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA

Journal of Molecular Diagnostics, ISSN: 19437811 15251578

Travis A. Clark; Jon H. Chung; Mark Kennedy; Jason D. Hughes; Niru Chennagiri; Daniel S. Lieber; Bernard Fendler; Lauren Young; Mandy Zhao; Michael Coyne; Virginia Breese; Geneva Young; Amy Donahue; Dean Pavlick; Alyssa Tsiros; Timothy Brennan; Shan Zhong; Tariq Mughal; Mark Bailey; Jie He; Steven Roels; Garrett M Frampton; Jill M. Spoerke; Steven Gendreau; Lackner; Erica Schleifman; Peters; Jeffrey S. Ross; Siraj M. Ali; Vincent A. Miller; Jeffrey P. Gregg; Phillip J. Stephens; Allison Welsh; Geoff A. Otto; Doron Lipson

September 1, 2018

Zinc finger protein 521 regulates early hematopoiesis through cell-extrinsic mechanisms in the bone marrow microenvironment

Molecular and Cellular Biology, ISSN: 10985549 02707306

Courtney J. Fleenor; Tessa Arends; Hong Lei; Josefine Ahsberg; Kazuki Okuyama; Jacob Kuruvilla; Susana Cristobal; Jennifer L. Rabe; Ahwan Pandey; Thomas Danhorn; Desiree Straign; Joaquin M. Espinosa; Søren Warming; Eric Pietras; Mikael Sigvardsson; Hagman

September 1, 2018

EGFL7 enhances surface expression of integrin α 5 β 1 to promote angiogenesis in malignant brain tumors

EMBO Molecular Medicine, ISSN: 17574684 17574676

Nevenka Dudvarski Stanković; Frank Bicker; Stefanie Keller; David T.W. Jones; Patrick N Harter; Arne Kienzle; Clarissa Gillmann; Philipp Arnold; Anna Golebiewska; Olivier Keunen; Alf Giese; von Deimling; Tobias Bäuerle; Simone P Niclou; Michel Mittelbronn; Weilan Ye; Stefan M. Pfister; Mirko HH Schmidt

September 1, 2018

MicroRNA–mRNA regulatory networks underlying chronic mucus hypersecretion in COPD

European Respiratory Journal, ISSN: 13993003 09031936

Hataitip Tasena; Alen Faiz; Timens; Jacobien Noordhoek; Machteld N. Hylkema; Reinoud Gosens; Pieter S. Hiemstra; Avrum Spira; Dirkje S. Postma; Tew; Michele A. Grimbaldeston; van den Berge; Irene H. Heijink; Brandsma

September 1, 2018

Effect of cell culture medium additives on color and acidic charge variants of a monoclonal antibody

Biotechnology Progress, ISSN: 15206033 87567938

Natarajan Vijayasankaran; Sharat Varma; Yi Yang; Steven Meier; Robert Kiss

September 1, 2018

An empirical approach leveraging tumorgrafts to dissect the tumor microenvironment in renal cell carcinoma identifies missing link to prognostic inflammatory factors

Cancer Discovery, ISSN: 21598290 21598274

Tao Wang; Rong Lu; Payal Kapur; Bijay S. Jaiswal; Raquibul Hannan; Ze Zhang; Ivan Pedrosa; Jason Luke; He Zhang; Leonard D. Goldstein; Qurratulain Yousuf; Yi-Feng Gu; Tiffani McKenzie; Allison Joyce; Min S. Kim; Xinlei Wang; Danni Luo; Oreoluwa Onabolu; Christina Stevens; Zhiqun Xie; Mingyi Chen; Alexander Filatenkov; Jose Torrealba; Xin Luo; Wenbin Guo; Jingxuan He; Eric Stawiski; Zora Modrusan; Durinck; Somasekar Seshagiri; James Brugarolas

September 1, 2018

Progress in understanding slow inactivation speeds up

Journal of General Physiology, ISSN: 15407748 00221295

Jian Payandeh

September 1, 2018

An introduced crop plant is driving diversification of the virulent bacterial pathogen Erwinia tracheiphila

mBio, ISSN: 21507511 21612129

Lori R. Shapiro; Joseph N. Paulson; Brian J. Arnold; Erin D. Scully; Olga Zhaxybayeva; Naomi E. Pierce; Jorge Rocha; Vanja Klepac-Ceraj; Kristina Holton; Roberto Kolter

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